OBJECT: Pre-ALL is a very rare preteukemic state, which percedes acute lymphocytic leukemia, while MDS(pre-ANLL), usually the well-known type of preleukemic state, precedes acute non-lymphocytic leukemia. Initially it shows transient pancytopenia without any evidence of leukemia in bone marrow findings, followed by acute lymphocytic leukemia after recovery from pancytopenia of a short period within weeks or months. We report a case with pre-ALL in childhood. CASE: A 15-month-old male baby was admitted with the complaints of fever and cough for 5 days and pallor for 2 weeks prior to admission. On admission, CBC showed pancytopenia without any evidence of leukemia, which was recovered spontaneously in a short period, and then was followed by acute lymphocytic leukemia of CALLA negative, early pre-B cell type. During antileukemic chemotherapy, he had suffered from severe bacterial infections and was finally died of sepsis 8 months after first admission. CONCLUSION: We report a case of pre-ALL in childhood, which was preceded by CALLA negative, early pre-B cell ALL, with a review of the literatures, briefly.
Bacterial Infections ; Bone Marrow ; Cough ; Drug Therapy ; Fever ; Humans ; Infant ; Leukemia ; Male ; Pallor ; Pancytopenia ; Precursor Cell Lymphoblastic Leukemia-Lymphoma* ; Precursor Cells, B-Lymphoid ; Sepsis

Sarcoidosis is a disease of unknown cause characterized by the presence of noncaseating granulomatous inflammation. Because the lungs and thoracic lymph nodes are almost always involved, most patients report acute or insidious respiratory problems. Although pulmonary manifestations are usually the major clinical concern in sarcoidosis, extrapulmonary involvement is common. We report a case of sarcoidosis of the axillary lymph nodes with no evidence of lung alteration.
Humans ; Inflammation ; Lung ; Lymph Nodes* ; Sarcoidosis*

No abstract available.
Wernicke Encephalopathy*

We investigated a correlation of serum prostate specific antigen(PSA) and preoperative prostatic volume measured by transrectal ultrasonography (TRUS) in 66 patients with pathologically con- firmed benign prostatic hyperplasia (BPH), as aids in the early detection of prostate cancer and in the improvement of specificity in BPH. The preoperative serum PSA value was also measured in 18 patients with pathologically confirmed prostate cancer and 15 men without prostatic disease as normal control using Tandem-R PSA radioimmunometric assay. There was a highly significant correlation between natural logarithm transformed PSA(In PSA) and non-transformed prostatic volume by linear regression analysis(r=0.6668, p<0.0001). Given above data, we determined a volume adjusted 95th percentile upper confidence limit for n PSA as an appropriate cutoff between normal and abnormal PSA value, according to prostatic volume in BPH. In the patients with BPH and prostate cancer, sensitivity, specificity, diagnostic accuracy and positive predictive value were 94%, 72%, 68% and 48%, respectively. A statistical results by the volume-adjusted cutoff for in PSA was similar to that at 10 ng/ml as cutoff for PSA value. Above 40ml in prostatic volume, however, a false positive rate was decreased in inverse proportion to prostatic volume in BPH. In summary, the prostatic volume must be considered in BPH patients with elevated serum PSA value, negative digital rectal examination and negative TRUS of prostate. And when the volume adjusted PSA cutoff is clinically applied to BPH patients for the early detection of prostate cancer, we thought that the false positive rate can be decreased in BPH patients.
Diagnosis* ; Digital Rectal Examination ; Humans ; Linear Models ; Male ; Prostate* ; Prostatic Diseases ; Prostatic Hyperplasia* ; Prostatic Neoplasms ; Sensitivity and Specificity ; Ultrasonography*

Color Doppler ultrasonography was performed in 41 patients with the acute onset of scrotal pain. of the 32 cases of 33 inflammatory diseases (epididymitis n=19, epididymo-orchitis n=12, orchitis n=1) color Doppler image demonstrated increased epididymal or testicular flow. Color Doppler ultrasonography correctly predicted the need for surgery in 5 of 9 operated patients and correctly predicted the outcome in all 32 nonoperated patients. In the two cases of 3 detorsions which were evident in color Doppler ultrasonography was incorrectly diagnosed with testis scintigraphy. Color Doppler ultrasonography is more effective than testis scintigraphy. Results show that color Doppler ultrasonography helps accurately correlate anatomy and perfusion in real time and may prove to be the definitive imaging technique for the diagnostic evaluation of the acute scrotum.
Humans ; Male ; Orchitis ; Perfusion ; Radionuclide Imaging ; Scrotum* ; Testis ; Ultrasonography, Doppler, Color*

No abstract available.
Trichotillomania*

Purpose: The aim of this study was to conduct research on the pre- treatment prognostic factors that may influence the continuation or cessation of adrenergic alpha-antagonist (alpha-blocker) in benign prostatic hyperplasic (BPH) patients. Materials and Methods: 56 patients who were responsive to alpha-blocker, and returned for follow-up for more than 5 months, were evaluated. The patients in whom the therapeutic effect persisted for more than 8 and for less than 4 weeks after cessation of alpha-blocker were designated as groups 1 (29 patients) and 2 (27 patients), respectively. An evaluation between the groups, based on age, prostate specific antigen (PSA), total prostate volume (TPV), transition zone volume (TZV), transition zone index (TZI), International Prostate Symptom Score (I-PSS), quality of life (QoL index), peak flow rate (Qmax), residual urine, and the duration of treatment, was conduct. All parameters were initially checked before medication. Results: This study showed that younger age, lower PSA level, smaller volume of residual urine and higher Qmax were useful indicators on the persistency of the therapeutic effect. However, TPV, TZV, TZI, I-PSS, QoL index and the duration of treatment did not affect the outcome. Conclusions: It was concluded that age, PSA, Qmax and residual urine measured before medication were useful pre-treatment prognostic factors in the prediction of the persistency of the therapeutic effect after cessation of alpha-blockers.
Adrenergic alpha-Antagonists* ; Follow-Up Studies ; Humans ; Lower Urinary Tract Symptoms* ; Prognosis ; Prostate ; Prostate-Specific Antigen ; Prostatic Hyperplasia* ; Quality of Life ; Recurrence*

A retroperitoneal lymphangioma is a rare tumor, most commonly affecting the neck or axillary area. We report a case of a 60-year-old man, with left flank pain, who had a retroperitoneal cavernous lymphangioma, with hemorrhagic complication. The diagnosis was made after complete excision of the tumor, followed by pathologic documentation.
Diagnosis ; Flank Pain ; Humans ; Lymphangioma* ; Middle Aged ; Neck ; Retroperitoneal Space*

No abstract available.
Brain Injuries* ; Brain* ; Dentate Gyrus*

No abstract available.
Candidiasis* ; Fluconazole*