No abstract available.

No abstract available.
Aged* ; Humans ; Nursing Homes* ; Nursing*

No abstract available.
Chromosome Aberrations* ; Ethylene Oxide* ; Lymphocytes* ; Transferases*

OBJECTIVE: We investigated the expression of uPA and uPAR in eutopic endometrium of advanced stage endometriosis and control patients. METHODS: The 33 endometriosis patients and 32 controls were enrolled. Endometrial samples were obtained from 65 premenopausal women aged 29~44 years, undergoing laparoscopic surgery or hysterectomy for non-malignant lesions. Sufficient samples were collected from 33 patients with endometriosis stage III and IV and 32 controls without endometriosis confirmed by laparoscopic surgery. The mRNA expression of uPA and uPAR from eutopic endometrium were analyzed by RT-QC PCR. RESULTS: The mRNAs of uPA and uPAR were expressed in eutopic endometrium from endometriosis and normal controls throughout the menstrual cycle. Uterine endometrium from women with endometriosis expresses significantly (p<0.05) higher levels of u-PA mRNA than endometrium from normal women without endometriosis in the proliferative phase. There were no significant differences in expression of uPAR in eutopic endometrium between controls and endometriosis patients. CONCLUSION: These results suggest that eutopic endometrium from endometriosis patients may be more invasive and prone to peritoneal implantation because of greater u-PA mRNA expression than endometrium from women without endometriosis. Thus, increased proteolytic activity may be one etiology for the invasive properties of the endometrium resulting in the development of endometriosis.
Endometriosis* ; Endometrium* ; Female ; Humans ; Hysterectomy ; Laparoscopy ; Menstrual Cycle ; Polymerase Chain Reaction ; Proteolysis ; RNA, Messenger* ; Urokinase-Type Plasminogen Activator

OBJECTIVE: We investigated the expression of TSP-1 and -2 in eutopic endometrium of advanced endometriosis and control patients. METHODS: The 33 endometriosis patients and 32 controls were enrolled. Endometrial samples were obtained from 65 premenopausal women aged 29-44 years, undergoing laparoscopic surgery or hysterectomy for non-malignant lesions. Sufficient samples were collected from 33 patients with endometriosis stage III and IV and 32 controls without endometriosis confirmed by laparoscopic surgery. The mRNA expression from eutopic endometrium for TSP-1 and -2 were analyzed by RT-QC PCR. RESULTS: The mRNAs of TSP-1 and -2 were expressed in eutopic endometrium from endometriosis and normal controls throughout the menstrual cycle. There were no significant differences in expression of TSP-1 and TSP-2 in eutopic endometrium between controls and endometriosis patients. CONCLUSION: Our results indicated that TSP-1 and -2 had no crucial role compared to other molecules in the regulation of angiogenesis. These findings also suggest that dysregulation of other angiogenic regulators would be concerned in pathophysiologic role in endometriosis development.
Endometriosis* ; Endometrium ; Female ; Humans ; Hysterectomy ; Laparoscopy ; Menstrual Cycle ; Polymerase Chain Reaction ; RNA, Messenger* ; Thrombospondin 1 ; Thrombospondins

A uremic patient on hemodialysis, who had concurrent cardiomyopathy showed intense myocardial uptake of (99m)Tc-methylene diphosphonate (MDP). The presumed cause of Uptake in the myocardium is metastatic calcification due to hypercalcemia secondary to the renal failure. However, supplementary mechanism caused by cardiomyopathy should be considered. We describe a case with bone tracer uptake in the myocardium in the absence of infarction in a patient with chronic renal failure,
Cardiomyopathies* ; Humans ; Hypercalcemia ; Infarction ; Kidney Failure, Chronic* ; Myocardium ; Renal Dialysis ; Renal Insufficiency ; Technetium Tc 99m Medronate*

No abstract available.
Glomerular Filtration Rate* ; Kidney*

A case of anencephaly associatied with twin pregnancy that delivered by primary lo-wer flap transverse cesarean section at 35-weeks of gestation is presented with brief revi-ew of literatures.
Anencephaly* ; Cesarean Section ; Female ; Humans ; Pregnancy ; Pregnancy, Twin*

The diagnostic work-up of renal mass should be carried out in an accurate, rapid, noninvasive and cost effective way. We retrospectively analyzed the diagnostic accuracy of ultrasonography, computerized tomography and renal angiography in 33 patients with renal mass from July 1984 to June 1987. The results were as follows : 1. The sex distribution of renal masses were 22 cases in male and 11 cases in female, and mean age of male patients were 43.8 years and female were 44.3 years. 2. The most common presenting symptom was flank pain in 28 cases(82.4%) and 17 cases (50.0%) presented with painless gross hematuria and one patient had no symptom. 3. Diagnostic accuracy of ultrasonography, computerized tomography and renal angiography of 27 cases of renal mass, were 70.6%, 83,3% and 63.3%, respectively. 4. Among 33 cases of renal mass, operation was done in 27 cases and 7 cases were misdiagnosed. 5. Therefore, we think that current uroradiologic studies are not sufficiently accurate in the diagnosis of renal mass and that exploration should be done whenever the diagnosis of renal mass is equivocal by radiologic study.
Angiography ; Diagnosis ; Female ; Flank Pain ; Hematuria ; Humans ; Male ; Retrospective Studies ; Sex Distribution ; Ultrasonography

The diagnostic work-up of renal mass should be carried out in an accurate, rapid, noninvasive and cost effective way. We retrospectively analyzed the diagnostic accuracy of ultrasonography, computerized tomography and renal angiography in 33 patients with renal mass from July 1984 to June 1987. The results were as follows : 1. The sex distribution of renal masses were 22 cases in male and 11 cases in female, and mean age of male patients were 43.8 years and female were 44.3 years. 2. The most common presenting symptom was flank pain in 28 cases(82.4%) and 17 cases (50.0%) presented with painless gross hematuria and one patient had no symptom. 3. Diagnostic accuracy of ultrasonography, computerized tomography and renal angiography of 27 cases of renal mass, were 70.6%, 83,3% and 63.3%, respectively. 4. Among 33 cases of renal mass, operation was done in 27 cases and 7 cases were misdiagnosed. 5. Therefore, we think that current uroradiologic studies are not sufficiently accurate in the diagnosis of renal mass and that exploration should be done whenever the diagnosis of renal mass is equivocal by radiologic study.
Angiography ; Diagnosis ; Female ; Flank Pain ; Hematuria ; Humans ; Male ; Retrospective Studies ; Sex Distribution ; Ultrasonography