No abstract available.
Bacillus* ; Humans ; Urinary Bladder Neoplasms* ; Urinary Bladder*

No abstract available.
Hepatitis B Surface Antigens* ; Interferons* ; Lymphocytes*

Herniated intervertebral disc(HIVD) of the lumbar spine has been known to be relatively uncommon in the teenager and frequently be associated with trauma. However, with the changing life style and increasing sports activities, and most of all, with the advent of new imaging modalities, the incidence seems to be increasing gradually. In order to define the characteristic pattern of HIVD of teenager in the era of MRI, and to clarify the associated lesions, such as apophyseal ring fractures, authors performed this retrospective study in 55 teenager patients with HIVD(77 discs), in which MRI was used as main diagnostic modality. The following results were obtained 1) The incidence of the HIVD in teenager was 9.6%(55 patients) of total HIVD patients(575 patients) for 4 years from December 1989 to December 1993. 2) According to MRI findings, HIVD of the teenager could be classified into 3 distinct patterns; simple HIVD, lumbar apophyseal ring fracture(LARF), and vertebral rim lesion. 3) In simple HIVD, as for the MRI classification, protruded type was most frequent type and there was no sequestered type 4) In LARF, the incidence was 14.4% of teenager's HIVD and posterocephalad margin of L5 was the most common site of involvement. 5) Exophytic bony protrusion from the posterior margin of vertebral body, which we called vertebral rim lesion, could be defined on MR sagittal view in 6 cases.
Adolescent ; Classification ; Humans ; Incidence ; Intervertebral Disc ; Life Style ; Magnetic Resonance Imaging ; Retrospective Studies ; Spine ; Sports

20 cases of study group whose follow-up period is over 6 months among 22 cases of bladder tumors treated with doxorubicin instillation following TUR during the period from December, 1981 through December, 1983 were compared with 30 cases of controlled group whose follow-up period is over 6 months among 32 cases of bladder tumors treated with thio-tepa instillation following TUR during the period from January, 1978 through June, 1981. Following result were obtained. 1. Recurrence rate In TUR + doxorubicin, 25%, In TUR+thio-tepa,30% 2. Interval between TUR & the first recurrence: In TUR + doxorubicin, average 9 months, In TUR + thio-tepa, average 8.1 months 3. Complication: In TUR + doxorubicin, painful urination in 2 cases(10%), In TUR + thio-tepa, hematuria, dysuria, painful urination, and urethral stricture in 8 cases(26.7%).
Doxorubicin* ; Dysuria ; Follow-Up Studies ; Hematuria ; Recurrence ; Thiotepa* ; Urethral Stricture ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urination

We have performed percutaneous extraction of renal and upper ureter stones in 54 cases with use of the Storz percutaneous universal nephroscope(26Fr). With the patient under general anesthesia, a percutaneous tract was dilated up to 24Fr and the stone was immediately removed at one session. A variety of grasping and fragmentation techniques under fluoroscopic and endoscopic control were used to extract stones. Overall success rate was 65%. With increasing proficiency from accumulation of experience, rate of stone extraction has been increasing from 40% early in the series to 83% in the most recent cases. The advantage of this technique is that only 1 to 2cm skin incision is required to remove the stone with minimal postoperative morbidity, rapid convalescence, and sooner return to work. We conclude that percutaneous nephrolithotripsy appears to be an appropriate alternative to an open operation in most patients with symptomatic urolithiasis.
Anesthesia, General ; Convalescence ; Hand Strength ; Humans ; Return to Work ; Skin ; Ureter ; Urinary Calculi ; Urolithiasis

Study group consists of 30 cases whose follow-up period is over 6 months among 32 cases of bladder tumors treated with thio-TEPA instillation following TUR during the period from January, 1978 through June, 1981. Control group consists of 25 cases whose follow-up period is over 6 months among 33 cases of bladder tumors treated by TUR only during the period from January, 1971 through December, 1977. Following results were obtained: 1. Recurrence rate: In study group, 30% In control group, 64% 2. Interval between TUR & the first recurrence: In study group, average 8.1 months In control group, average 7.1 months 3. Number of tumors at first recurrence: In study group: 89%: under 2 11%: over 3 In control group: 25%: under 2 75%: over 3
Follow-Up Studies ; Recurrence ; Thiotepa* ; Urinary Bladder Neoplasms* ; Urinary Bladder*

The main problems of transurethral prostatectomy were intraoperative blood loss and absorption or irrigating fluid. The reduced serum sodium concentration and osmolality. regarded as cause of TURP syndrome. was caused by dilution by several liters of irrigating fluid. Early recognition. while surgery is being performed is important to prevent development of hypovolemia. especially in the aged group. From January 1990 to June 1990. prospective study for the determination of the amount of irrigating fluid absorbed by use of plasma sorbitol concentration, serum electrolytes change and other related factors was undertaken in 30 patients undergoing TURP with manufactured URIONE solution (sorbitol 2.7 gm+mannitol 0.54 gm/100 ml distilled water) as irrigating fluid. An accurate measurement of plasma sorbitol concentration absorbed was obtained by Beutler`s enzymatic sorbitol analysis. Statistical evaluation of all data obtained was made using the `t-test` with significance at 0.1 percent or less. Mean plasma sorbitol concentration absorbed, blood loss. absorbed irrigating fluid volume were 474.2+/-344.3 mg/1.216 ml and 554.3+/-300.2 ml, respectively. A statistically significant positive interrelationship was found among absorbed plasma sorbitol concentration, serum sodium change and absorbed irrigating fluid volume (p<0.001). Also significant correlations could be obtained between absorbed irrigating fluid volume and serum sodium change (p<0.001).
Absorption ; Electrolytes ; Humans ; Hypovolemia ; Osmolar Concentration ; Plasma* ; Prospective Studies ; Sodium ; Sorbitol* ; Transurethral Resection of Prostate*

Patients with advanced urothelial tumors that relapse or persist following conventional therapy have poor prognosis. Management of the patients with recurrent local or disseminated urothelial tumors presents a difficult clinical problems. In 1985 Sternberg et al reported 71% of significant tumor regression and 50% of complete clinical remission with M-VAC (methotrexate, vinblastine, doxorubicin and Cisplatin) combination chemotherapy for treatment of advanced urothelial transitional cell carcinomas. Herein, we have experienced 13 cases of M-VAC combination chemotherapy in advanced urothelial tumors. Complete and partial remission was in achieved 46.2 per cent of the patients clinically, while 15.4 percent had a minor response and 38.4 per cent had progression with median survivals of 11.5, 8.5 and 7.4 months. Toxicity was significant. 15.4 per cent of the patients having experienced nadir sepsis, 30.8 per cent mucositis and 7.6 per cent cardiac toxicity. Median cycle length varied from 31.6 to 41.7 days for the first and 5th cycle respectively. This regimen has been efficacious in selected patients with advanced urothelial tumors.
Carcinoma, Transitional Cell ; Doxorubicin* ; Drug Therapy, Combination ; Humans ; Mucositis ; Prognosis ; Recurrence ; Sepsis ; Vinblastine*

No abstract available.

Intravesical Bacillus Calmette-Guerin(BCG) Has been shown to be effective therapy and prophylaxis against recurrent tumor in patients with superficial bladder cancer(stages O and A), including carcinoma in situ. Tice-Chicago strain bacillus Calmette-Guerin was used to treat superficial transitional cell carcinoma of the bladder in 26 patients between July, 1985 and March, 1988. A variety of different BCG treatment regimens have been used that vary in intensity. In general, treatment results have been more favorable with intensive regimens. However, the toxicity also has been substantially greater with intensive regimens. The optimal regimen has yet to be determined. Our treatment regimen of 120mg. Tice-Chicago strain BCG weekly for 6 weeks and then monthly for 3 months was well tolerated. 20 patients had a complete response and 6 patients had a tumor recurrence at 21 months mean follow-up, resulting in 77% of response rate. Side effects during or shortly after treatment were minor and self- limiting in the majority of patients(fever, bladder irritability and hematuria). This experience supports the efficacy of bacillus Calmette-Guerin as a cost-effective, well- tolerated treatment modality for patients with superficial transitional cell carcinoma of the bladder.
Bacillus ; Carcinoma in Situ ; Carcinoma, Transitional Cell* ; Follow-Up Studies ; Humans ; Mycobacterium bovis ; Recurrence ; Urinary Bladder Neoplasms ; Urinary Bladder*