2.Renin Assay: Part 1. Study on Plasma Renin Activity in Various Diseases.
Korean Circulation Journal 1973;3(1):19-31
1. Present study was made to observe the plasma renin activity in the patients of benign essential hypertension, malignant hypertension, acute or chronic glomerulonephritis, liver cirrhosis with or without ascites, congestive heart failure, and massive bleeding due to various causes. 2. It was found that the substance with constrictive action on the rat colon had the hypertensive action. 3. The normotensive group showed the renin activity of 1.81+/-1.18ng/ml. 4. Benign hypertension group showed the level of 3.14+/-3.27 ng/ml which was the significantly elevated level compared to the normal group. 5. Malignant hypertensive group showed 8.47+/-9.48 ng/ml, which was not only the apparently elevated value than that of normal group, but also showed significant difference from that of benign essential hypertension. 6. The levels of 5.6+/-2.88 ng/ml and 27.5+/-12.36 ng/ml in chronic and acute glomerulonephritis respectively showed the significantly elevated level than the normal group, and the difference between the acute and chronic glomerulonephritis was also found to be significant. 7. The hepatic cirrhosis with or without ascites showed the level of 3.77+/-2.83 ng/ml and 0.80+/-0. ng/ml respectively. The value of the former was the significantly elevated compared with the normal group, and the later was lowered. 8. The level of 11.11+/-4.12 ng/ml was significantly elevated compared to that of normal group in congestive heart failure. 9. It is suggested that the renin activity assumes to be changed to the kind and the phase of the diseases and according to present data of elevated renin activity in essential hypertension, renin may play a secondary role in essential hypertension rather than to be a primary.
Animals
;
Ascites
;
Colon
;
Glomerulonephritis
;
Heart Failure
;
Hemorrhage
;
Humans
;
Hypertension
;
Hypertension, Malignant
;
Liver Cirrhosis
;
Plasma*
;
Rats
;
Renin*
3.Schwannoma of the Adrenal Gland: A case report.
Yong Chan CHUN ; Sun Hee SUNG ; Chan Il PARK
Korean Journal of Pathology 1993;27(4):424-426
Retroperitoneum is often the site of occurrence of schwannoma, but reports on schwanoma of the adrenal gland is exceptional and only 4 cases have been documented in the literature. This report is to add one such case occurred in a 53 year-old male who had anorexia, nausea and indigestion for one month. Whole body bone scan and abdominal CT scan revealed a 10 cm sized solid mass at upper pole of the left kidney. Under the impression of renal cell carcinoma, an operation was performed. The tumor was well encapsulated and appeared not to involve the kidney. The cut surfaces were light yellow and seemed to be composed of several hard lobules with areas of mucoid, cystic and calcific changes. No adrenal gland was identified grossly. But microscopically, the tumor was found to be partly surrounded by a small portion of adrenal cortical tissue. Histologically the tumor was a typical schwannoma with Verocay bodies, although modified in some extents by mucoid degeneration, cystic change, hyaline change and focal calcification. It is worthwhile to remember that the retroperitoneal schwannoma commonly had a huge size, sometimes involving the adjacent structures.
Male
;
Humans
4.Clinical observation on juvenile theumatoid arthritis.
Journal of the Korean Pediatric Society 1991;34(8):1123-1131
No abstract available.
Arthritis*
;
Arthritis, Juvenile
5.A Clinical and Histopathologic Study of Epidermal Cysts.
Annals of Dermatology 1994;6(2):157-161
BACKGROUND: Epidermal cysts are the most common of all cysts. OBJECTIVE: The purpose of this paper is to report the clinical and histopathologic features of epidermal cysts. METHODS: We reviewed the clinical and histopathologic features of 205 cases that were diagnosed with epidermal cysts at the department of dermatology in Anam Hospital of Korea University for 11 years, from January 1983 to December 1993. RESULTS: 1. Of the 3,400 cases of skin biopsy specimens, 205 cases were epidermal cysts(6%). There were 141 male cases (68.8%) and 64 female cases (32.2%). The ratio of male to female was 1:0.45. 2. Most patients with epidermal cysts belonged to age ranging from 20 to 59 with the highest incidence in the 3rd decade. 3. The site of predilection of the epidermal cysts were face 94(45.9%), trunk 37(18.0%), neck 23(11.2%), leg 21(10.2%), arm 19(9.3%),scalp 7(3.4%), scrotum 2(1.0%), and vagina 2(1.0%). 4. Histopathologically, 61 cases (29.3%) were ruptured. The most common cystic wall change was acanthosis followed by atrophy, hyperplasia, hypergranulosis, parakeratotis, basalioma-like change, squamous eddies, dyskeratosis. The most common cystic content was keratinous material followed by parakeratotic cells, pigment, bacterial colony, RBC, inflammatory cells, hair shaft, calcification, trichilemmal keratinization, pilomatricoma-like change. The most common stromal change was giant cells followed by fibrosis, granulation tissue formation,vessel proliferation, pigment. CONCLUSION: According to our results, which agree with those of Chung, the epidermal cysts occur as a disease particular to young men, especially on the face. Histopathologically, when an epidermal cyst ruptures and the contents of the cyst are released into the dermis, a considerable foreign body reaction with numerous multinucleated giant cells results.
Arm
;
Atrophy
;
Biopsy
;
Dermatology
;
Dermis
;
Epidermal Cyst*
;
Female
;
Fibrosis
;
Foreign-Body Reaction
;
Giant Cells
;
Granulation Tissue
;
Hair
;
Humans
;
Hyperplasia
;
Incidence
;
Korea
;
Leg
;
Male
;
Neck
;
Rupture
;
Scrotum
;
Skin
;
Vagina
6.A Case of Epidermolysis Bullosa Simplex ( Dowling - Meara Type ).
Korean Journal of Dermatology 1994;32(4):735-739
The Dowling-Meara type of epidermolysis bullosa simplex(EBS) is genetic disease that is transmitted as an autosomal dominant trait and is charscterized clinically by pherpetiform clustering of blisters and palmo-plantar keratoderma. The disease usually presents at with or in early infancy. Although serious and hemorrhagic Wers may occur on any part of the body, the lesions heal without scaning in general. The disease shows a tendency to improve by progressian of age and it usually follows a relatively benign course. Microecopically, there are intraepidermal bli.ter s forming as a result of cytolysis of basal cells. In addition, the is a highly characteristic clumping of tonofilaments of keratinocytes in the lower epidermis, which is not seen in any other form of EBS. We report a case of Dowling-Meara type of EBS that is first destribed in Korean medical literatures.
Blister
;
Epidermis
;
Epidermolysis Bullosa Simplex*
;
Epidermolysis Bullosa*
;
Intermediate Filaments
;
Keratinocytes
7.The fetal acidemia, assessed by the biophysical profile.
Korean Journal of Obstetrics and Gynecology 1993;36(7):1882-1892
No abstract available.
8.A clinical study of bloody nipple discharge.
Journal of the Korean Surgical Society 1993;44(6):809-813
No abstract available.
Nipples*
9.A Randomized Double - Blind Clinical Trial of 2,000cc vs. 4,000cc Preparation with Balanced Lavage Solution (Golytely) for Colonoscopy.
Chan Wook PARK ; Moon Sung LEE ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):369-378
To determine the most effective and tolerable method of preparation with Golytely for colonoscopy, 141 consecutive cases were randomly allocated to drink either 2,000cc(74 cases, Group I) or 4,000cc(67 cases, Group 2), with infusion rate of 1,000cc/h. The reaults were as follows. 1) The rates of effective colonic clearance in group 1 and group 2 was 94.6% and 94.0%, respectively. There is no significance difference between two groups. 2) There was no significant difference in the ingested volume until the first bowel movement and the time required for rectal efflunt to be clear between two groups. 3) Patient acceptance was higher in group 1 than in group 2. 4) Side effects were less noticed in group 1 than group 2, and incraased in body weight (average 0.8 kg) after ingestion of Golytely was observed only in group 2.
Body Weight
;
Colon
;
Colonoscopy*
;
Eating
;
Humans
;
Therapeutic Irrigation*
10.Endoscopic Prosthesis in Malignant Stricture.
Moon Sung LEE ; Chan Wook PARK ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):363-367
Non-operative palliative treatment for malignant colonic obstruction can sometimes be accomplished by the insertion of anorectal tube, endoscopic balloon dilation or endoscopic laser therapy. But these methods have some disadvantages, such as limitaation of activity, need of repetitive treatment and high-risk of perforation. Endoscopic prosthesis is generally accepted as a safe, effective palliative treatment for malignant esophageal stricture, because this method has no above disadvantages. Neverthless, there is only a few experence with endoecopic prosthesis in malignant colorectal stricture over the world. We report two cases which were safely, effectively performed endoscopic prosthesis in palliative treatment for their malignant rectal strictures.
Colon
;
Constriction, Pathologic*
;
Esophageal Stenosis
;
Laser Therapy
;
Palliative Care
;
Prostheses and Implants*