No abstract available.
Granuloma, Pyogenic* ; Port-Wine Stain*

No abstract available.
Humans ; Inpatients*

The conversion of the ankylosed hip to a total hip arthroplasty may be indicated if a fused hip causes low back pain, pain in the ispilateral knee, or a fibrous ankylosis is painful. Fifteen hips converted to total hip arthroplasty between Aug., 1982 and Jul., 1988 have been reviewed one to seven years after operation and the results are as follows:1. Among the 15 hips, 8 cases confirmed as fibrous ankylosis and 7 cases confirmed as bony ankylosis. 2. The causes of ankylosis is as follow tuberculous arthritis(4 cases), secondary osteoarthritis due to pyogenic hip(4 cases), rheumatoid arthritis(4 cases), post-traumatic arthritis secondary to central fracture-dislocation of hip(2 cases), and ankylosing spondylitis(1 cases). 3. The duration of immobility of the involved hip ranged from two to twenty-five years. 4. In the 14 patients, three complained of low back pain, five of ipsilateral knee pain and six of ipsilateral hip pain. 5. The lower back pain due to malposition was relieved in all cases except ankylosing spondylitis, and the pain in ipsilateral knee was also relived in all cases after hip arthroplasty. 6. The average Harris score of the fifteen hips before arthroplasty and after was 50.1 and 88.1.
Ankylosis ; Arthritis ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Hip ; Humans ; Knee ; Low Back Pain ; Osteoarthritis ; Spondylitis, Ankylosing

The Cronkhite-Canada syndrome is a rare, non-neoplastic, non-hereditary condition which consists of gastrointestinal polyposis associated with alopecia, onychodystrophy and hyperpigmentation of the skin. It usually encountered with severe diarrhea, weight loss and other malabsorption symptoms. The etiology of the condition is unknown. Usually, this syndrome is associated with a poor prognosis due to the effect of malabsorption and generalized debility. We report a case of this syndrome showing unusually rapid improvement after 3-month following only conservative treatment. To our knowledge, this is the first case report of Cronkhite-Canada syndrome in the Karean dermatologic literature.
Alopecia ; Diarrhea ; Hyperpigmentation ; Intestinal Polyposis* ; Prognosis ; Skin ; Weight Loss

No abstract available.
Mediastinitis*

A complex syndrome, later called as Prader-Willi syndrome, was first described in 1956 by Prader et al, and Zellweger and Schneider characterized this syndrome as hypogonadism, hypotonia, hypomentia and boesty. It is not rare in western countries and more than 400 cases have been reported until 1983. But our interest arose because of our recent experience of diffuse noncirrhotic fibrosis of the liver in a 6 year-old boy who had the clinical features of Prader-Willi syndrome. The core of liver showed destruction of most of the hepatic lobules, particularly of the acinar zone 3, and replacement bt diffuse fibrosis. The remaining liver cells underwent fatty change, and the overall changes resembled chronic sclerosing hyaline disease of the alcoholic type. Inflammation was negligible. This particular case suggests that the severe fatty change of liver could result in irreversible damage to the hepatocytes and progressive fibrosis.

Seventeen cases of paralytic strabismus secondary to abducens nerve palsy were treated with an injection of Botulinum Toxin A(Oculinum(R)) into the medial rectus muscle under the electromyographic control. All 17 cases, including 3 cases of bilateral abducens palsy, were followed up for 6 months to 23 months after the initial injection, there were no systemic side effects. The etiologic factors follow up deviation angle, dosage and complications were analyzed In the Thirteen cases of Oculinum(R) injection in antagonistic medial rectus muscle, the mean correction of preinjection deviation was 48.7%; the four cases who underwent both Jensen's operation and Oculinum(R) injection obtained 64.6%. The most common complication was ptosis which developed in 15 cases(64.7%) with a dosage of 2.75 u or above. From this study. we concluded that Oculinum(R) chemodenervation was effective in the acute case of abducens palsy without the anterior segment ischemia and systemic side effects.
Abducens Nerve Diseases* ; Abducens Nerve* ; Botulinum Toxins* ; Electromyography ; Follow-Up Studies ; Ischemia ; Nerve Block ; Paralysis ; Strabismus

BACKGROUND: Preservation of antigen determinants while retaining morphological detail is prerequisite for high quality immunohistochemistry. Conventional formalin fixation and paraffin embedding procedures are useful in preserving tissue architecture and cytologic detail. However, they destroy the antigenicity of many proteins is tissue samples. On the other hand, fresh frozen section preserve the antigenicity of most proteins, but vield poor morphological preservation. OBJECTIVE: The purpose of this study is to evaluate the AMeX method as to the ability to preserve both antigenicity and morphologic details of the skin basement membrane zone so that precise localization of antigens can be attained in immunohistochemistry. METHODS: Tissues were fixed in acetone at -20degrees C over night, then cleared in methyl benzoate and xylene, consecutively, and embedded in ordinary paraffin at 58-60degrees C. Sections made from this paraffinembedded tissue were stained with hematoxylin and eosin for a morphologic study and immunolabelled with antibodies against major basement membrane antigens to evaluate antigenic preservation. The staining intensity and preservation of the morphology by the AMeX method were compared with conventional formalin processed tissues and frozen tissues. RESULTS: Morphological preservation of the AMeX method-processed sections was good throughout the epidermis, basement membrane, and dermis, and as good as that of routinely formalin-fixed paraffin-embedded sections. Frozen sections usually revealed revealed various degrees of damage by ice crystal formation throughout the epidermis to the dermis. The AMeX method-processed sections showed better or same antigenic preservation comparing the frozen sections when the sections were immunolabelled with specific monoclonal antibodies. But, when the sections were immunolabelled with patient's sera, the AMex method showed less antigenic preservation than the frozed sections. The anti-type IV collagen monoclonal antibody exhibited immunoreactivity only conventional formalin-fixed paraffin-embedded skin sections, but the intensity of the staining was weaker than the AMeX processed sections and the frozen sections. CONCLUSION: The AMeX method can be utilized for the demonstration of skin basement membrane antigens and is superior to the fresh-frozen method in that the histologic figures are more distinct and antigencity can be preserved for a long time.
Acetone* ; Antibodies ; Antibodies, Monoclonal ; Basement Membrane* ; Benzoates* ; Collagen ; Dermis ; Eosine Yellowish-(YS) ; Epidermis ; Formaldehyde ; Frozen Sections ; Hand ; Hematoxylin ; Ice ; Immunohistochemistry ; Paraffin ; Paraffin Embedding ; Skin* ; Xylenes*

No abstract available.
Animals ; Liver* ; Pancreas* ; Rats* ; Vitamin A* ; Vitamins*

Oculopharyngeal muscular dystrophy, one of the variants of chronic progressive external ophthalmoplegia, is a disorder characterized by progressive bilateral ptosis, immobility of the eyes and dysphagia. We have experienced a 46-year-old woman complaining of bilateral ptosis, mild dysphagia and immobility of the eyes. Oculopharyngeal muscular dystrophy was confirmed by clinical, electromyographic and histopathologic examination. Therefore, we report a case of oculopharyngeal muscular dystrophy with review of literatures.
Deglutition Disorders ; Female ; Humans ; Middle Aged ; Muscular Dystrophy, Oculopharyngeal* ; Ophthalmoplegia, Chronic Progressive External