The purpose of this study was to provide quantitative data describing the effect of rapid palatal expansion (RPE) on nasal airway resistance (NAR). RPE is an orthopedic procedure which is commonly used to widen the maxilla in skeletal Class III patients. 18 subjects (9 males and 9 females, mean age: 10 years 7 months) were selected from the Orthodontics in Yongdong Severance Hospital. Recordings of NAR were taken by active anterior method prior to expansion, immediately after desired maximum expansion, and after approximately 3 months and 6 months, and 1 year. All data was recorded and statistically processed with the SPSS program of IBM PC system. The results are as followings: 1. The average initial NAR of the subjects was 3.84cm H2O/LPS (SD +/- 1.34). It was greater than the average NAR of the normal subjects. 2. Among 18 subjects, 9 subjects showed reduction of NAR and 9 subjects showed no specific change of NAR after expansion. 3. An average reduction in NAR after immediately expansion was statistically significant at the 0.05 level. 4. The reduction appeared stable throughout the post treatment observation period of 1 year after expansion. From these results, it was suggested that RPE is a useful method to reduce NAR.
Airway Resistance* ; Female ; Humans ; Male ; Maxilla ; Orthodontics ; Orthopedic Procedures ; Rhinomanometry*

No abstract available.

The role of surgical wire in the bone and joint surgery is very important. To get a maximum effect of the surgical wiring, the orthopaedic surgeon should not only select appropriate wire diameter but also apply adequate wiring technique. When strong fixation is required, wire loops are frequently untrustworthy. These are due to insufficient caliber or inadequate technique of wire thightening and/or twisting. The theoretical background for effective wiring technique and useful diameter in cerclage wiring is poor. Ultimate stress and stress at breaking point of different diameter of the wire was higher in 16G than 18G or 21G. Twist knot was stronger than knot twist. Wire holder was more effect than tensioner(york). Tension tightening with twist knot by wire holder have been found most suitable for internal fixation by surgical wire.
Joints

Postoperative total blindness was seen in a 48 year old male who had a laparotomy for traumatic perforation of intestine. General inhalation anesthesia of ether-oxygen-mask with semiclosed system was applied after initial ketamine administration. This unhappy ocular complication could be occur secondary to excessive prolonged external compression to eyeballs with mask or/and prolonged postoperative hypotension.
Anesthesia, General* ; Anesthesia, Inhalation ; Blindness* ; Humans ; Hypotension ; Intestines ; Ketamine ; Laparotomy ; Male ; Masks

Liposarcoma is one of the most common soft tissue sarcomas that occurs in adults and is currently divided into five main subgroups: well-differentiated, myxoid, round cell, pleomorphic, and dedifferentiated. Primary mesenteric liposarcoma is extremely rare, and the treatment strategy is surgical resection with a wide free margin, often followed by radiation and adjuvant chemotherapy if distant metastasis is not detected. A 73-year-old male patient presented with lower abdominal distension. Abdominal CT scan revealed a large homogeneously enhancing mass lesion abutting the sigmoid colon and urinary bladder. At laparotomy, the solid mass measured 28x26x12 cm in size, was well-demarcated, and originated from the mesentery of the middle ileum. It was removed along with some small intestine (ileocecal valve upper 50-150 cm) and ileal mesentery because of adhesion. Histologically, the tumor proved to be pleomorphic liposarcoma. The patient did not undergo any adjuvant treatment following surgery, but he remains disease free until 33 months after surgery. Herein, we report a case of pleomorphic liposarcoma arising from small bowel mesentery.
Aged ; Humans ; Liposarcoma/*diagnosis/pathology/surgery ; Male ; Mesentery/*pathology ; Peritoneal Neoplasms/*diagnosis/pathology/surgery ; Tomography, X-Ray Computed

Fabry's disease is a rare, inborn error, sex-linked disorder of glycosphingolipid metabolism with death occurring from myocardial or renal involvement at 4th or 5th decades. The primary metabolic defect lies in the deficient tissue activity of the enzyme alpha-galactosidase A which results in progressive accumulation of the specific neutral glycosphingolipids, cerebroside dihexoside(CDH) and cerebroside triihexoside(CTH), within the lysosomes of endothelial, perithelial and smooth muscle cells of the cardiovascular and renal systems predominantly. Clinical manifestations are sequelae of the anatomic and physiologic alterations produced by the progressive deposition of glycosphingolipid in the tissues. We report the first case of successful renal transplantation in a patient with Fabry's disease in Korea. The patient was a 33-year-old male. Fabry's disease was confirmed by measurement of serum alpha- galactosidase level and renal biopsy. Biopsy finding showed lamellar inclusion bodies on electron microscopy. Galactosidase activity was also markedly decreased. He has been well for 49 months.
Adult ; alpha-Galactosidase ; Biopsy ; Fabry Disease* ; Galactosidases ; Humans ; Inclusion Bodies ; Kidney Transplantation* ; Korea ; Lysosomes ; Male ; Metabolism ; Microscopy, Electron ; Myocytes, Smooth Muscle ; Neutral Glycosphingolipids ; Transplantation

Fabry's disease is a rare, inborn error, sex-linked disorder of glycosphingolipid metabolism with death occurring from myocardial or renal involvement at 4th or 5th decades. The primary metabolic defect lies in the deficient tissue activity of the enzyme alpha-galactosidase A which results in progressive accumulation of the specific neutral glycosphingolipids, cerebroside dihexoside(CDH) and cerebroside triihexoside(CTH), within the lysosomes of endothelial, perithelial and smooth muscle cells of the cardiovascular and renal systems predominantly. Clinical manifestations are sequelae of the anatomic and physiologic alterations produced by the progressive deposition of glycosphingolipid in the tissues. We report the first case of successful renal transplantation in a patient with Fabry's disease in Korea. The patient was a 33-year-old male. Fabry's disease was confirmed by measurement of serum alpha- galactosidase level and renal biopsy. Biopsy finding showed lamellar inclusion bodies on electron microscopy. Galactosidase activity was also markedly decreased. He has been well for 49 months.
Adult ; alpha-Galactosidase ; Biopsy ; Fabry Disease* ; Galactosidases ; Humans ; Inclusion Bodies ; Kidney Transplantation* ; Korea ; Lysosomes ; Male ; Metabolism ; Microscopy, Electron ; Myocytes, Smooth Muscle ; Neutral Glycosphingolipids ; Transplantation

The purpose of this study was to estimate the national prevalence of childhood asthma and other allergic diseases in Korea, and to determine potential risk factors for the diseases. Stratified random samples of 42,886 were selected from 34 elementary (6-12 yr olds) and 34 middle schools (12-15 yr olds) nationwide, and 38,955 were in the final analysis. The Korean-translated modified version of the International Study of Asthma and Allergies in Childhood questionnaire was used in this cross-sectional survey. Twelve-month prevalences of the symptoms of asthma, rhinoconjunctivitis, and flexural eczema were 8.7%, 10.5%, 7.3% in 6-12 yr olds, and 8.2%, 10.0%, 3.9% in 12-15 yr olds, respectively. For allergic conjunctivitis, food allergy, and drug allergy, the prevalences in 6-12 yr olds were 11.2%, 6.5%, and 1.5%, respectively. Asthma and flexural eczema decreased significantly with age. Other significant risk factors were also noted. For 6-12 yr-old asthma, adjusted odds ratio (aOR) of body mass index was 1.21 with 95% confidence interval (CI) 1.0-1.48, aOR of passive smoking was 1.37 with 95%CI 1.24-1.51, aOR of carpet use was 1.28 with 95%CI 1.10-1.49. For 6-12 yr-old eczema, aOR of affluence was 1.22 with 95%CI 1.07-1.39. The control of obesity and passive smoking would be the most important preventive measures of allergic diseases.
Adolescence ; Age Distribution ; Asthma/*epidemiology ; Child ; Conjunctivitis, Allergic/*epidemiology ; Drug Hypersensitivity/epidemiology ; Eczema/*epidemiology ; Female ; Food Hypersensitivity/epidemiology ; Human ; Korea/epidemiology ; Male ; Prevalence ; Questionnaires ; Risk Factors ; Sex Distribution

About 90% of primary gastrointestinal lymphomas originate from the B-cell and less than 10% from the T-cell. In respect of anatomical location, the stomach is the most common site of gastrointestinal lymphomas followed by the ileum, colon, and rectum. However, esophagus and duodenal lymphomas are infrequently involved. Primary T-cell lymphoma of the duodenum is not common and peripheral T-cell lymphoma of the duodenum is very rare. In Korea, there has been no case report of peripheral T-cell lymphoma which simultaneously involved the stomach and duodenum. In this report, we present a case of primary peripheral T-cell lymphoma of the duodenum and stomach. A 63-year-old man was hospitalized complaining of weight loss of 15 kg and dyspepsia for 2 months. Esophagogastroduodenoscopy showed a large annular infiltrative lesion in the descending portion of the duodenum. At the posterior side of the upper body of the stomach, an ill-defined, broad, flat, and infiltrative lesion was also noted. Microscopic examination of the biopsy specimen showed that atypical bizzare lymphocytes infiltrated the mucosa of the duodenum and stomach. The lymphocyte was positive for CD3, CD5 and negative for CD20, CD23, and CD56 by immunohistochemistry. We made a diagnosis of primary peripheral T-cell lymphoma of the stomach and duodenum. We report a case of peripheral T-cell lymphoma of the stomach and duodenum with a review of the literature.
B-Lymphocytes ; Biopsy ; Colon ; Diagnosis ; Duodenum* ; Dyspepsia ; Endoscopy, Digestive System ; Esophagus ; Humans ; Ileum ; Immunohistochemistry ; Korea ; Lymphocytes ; Lymphoma ; Lymphoma, T-Cell ; Lymphoma, T-Cell, Peripheral* ; Middle Aged ; Mucous Membrane ; Rectum ; Stomach* ; T-Lymphocytes ; Weight Loss

In mammals, the ovary proceeds follicular development and atresia during the reproductive cycle. Follicular atresia occurs through apoptosis, programmed cell death (PCD) which is mediated by gene controlling apoptosis and cell cycle. Regulatory genes of apoptosis and cell cycle have previously reported. Recently, the products of bcl-2, bax, Fas, and TNF-a genes were reported to play critical roles in apoptosis, and the products of p21, p27, p57, and p53 genes were known to play many roles in cell cycle. In these genes, bcl-2 is known as a apoptosis inhibitor in the ovary, while p57 which was recently reported to express in the testis and other several organs, is a cyclin dependent kinase inhibitor (CDI). We thought that these genes are associated with follicular development and atresia. Therefore, the present study used a in situ hybridization to examine the expression of these two genes, followed by synthesis of a radioisotope labelled cRNA probes during PMSG-induced follicular development and atresia in the immature rat ovary. Morphological changes were occurred with the manner of 5 days periodicity after PMSG treatment. 1 or 2 days after PMSG treatment, the ovaries have showed growing follicles with antrum and healthy granulosa cells. The ovaries of 3 days after treatment were appeared continuous growing follicles and some degenerating follicles which had thinner granulosa cell layers than growing follicles. But the ovaries of 4 or 5 days have showed degenerating follicles which have pyknotic nuclei and thin distorted granulosa cell layers. These atretic follicles showed positive reaction with DNA end labelling method indicating apoptotic processes. In situ hybridization signals to p57 cRNA probe were expressed in the theca externa cells of the control ovary. In PMSG treated 4 or 5 days ovaries, the atretic follicles have showed stronger signals than 1 or 2 days growing ovarian follicles. But the signals to bcl-2 cRNA probe were expressed in the ovarian theca and interstitial cells including theca basement membrane. And this signals were decreased in the 4 or 5 days atretic follicles and interstitium. According to these data, we suggest that these two genes are associated to follicular development and atresia via individual up- and down regulatory mechanism.
Animals ; Apoptosis ; Basement Membrane ; Cell Cycle ; Cell Death ; Cyclins ; DNA ; Female ; Follicular Atresia* ; Genes, bcl-2 ; Genes, p53 ; Genes, Regulator ; Granulosa Cells ; In Situ Hybridization ; Mammals ; Ovarian Follicle ; Ovary* ; Periodicity ; Phosphotransferases ; Rats* ; RNA, Complementary ; RNA, Messenger* ; Testis ; Theca Cells