We report a case of Winkelmann granuloma in a 63-year-old man. nstopathological findings of the biopsy specimens from the lesions of the ear, finger and iliac crest area were compatible with Winkelmann granuloma. Winkelmann granuloma is a rare disorder showing an association with systemic immunoreactive disorders. Although our patient did not have any definite systemic disease, he had characteristic clinical and histopathological findings of Winkelmann granuloma, arthralgia, an elevated erythrocyte sedimentation rate, positivity to the rheumatoid factor and antinuclear antibodies. Therefore, we believed that he was strongly suspected to have an unclassifiable systemic immunoreactive disease.
Antibodies, Antinuclear ; Arthralgia ; Biopsy ; Blood Sedimentation ; Ear ; Fingers ; Granuloma* ; Humans ; Middle Aged ; Rheumatoid Factor

No abstract available.
Osteochondritis ; Osteochondritis Dissecans

We report a case of histiocytoid hemangioma (angiolymphoid hyperplasia with eosinophilia) in a 60 year-old female patient who was effectively treated with dapsone. The therapeutic effect of dapsone may support the hypothesis that immunologically mediated reactive process plays a role in the pathogenesis of histiocytoid hemangioma.
Dapsone* ; Female ; Hemangioma* ; Humans ; Hyperplasia* ; Middle Aged

This study investigated the stress of community residents in Kwang-Ju and Chonnam areas by using the General Health Questionnaire(GHQ-60) as a instrument of stress measurement. The number of subject were 445 residents who lived in three areas (large city, middle city, and rural area) and they were individually interviewed in March, 1994. The result of study showed that the degrees of stress measured by GHQ-60 were statistically significant in the residents' area, age. sex variables: (a) the residents in middle city among three area had the highest level of stress: (b) the resident who were more than 60 in age had the highest level of stress: (c) the female resident had more stress than male residents: (d) particularly, the residents who were more than 60 years old in the middle city had the highest level of stress. Further, the results of factor analysis showed that there were three factors of social dysfunction, depression and anxiety, and psychosomatic symptom. The social dysfunction factor was statistically significant in both age and resident area variables. The depression and anxiety factor was statistically significant in the residents' area, age. sex variables. The psychosomatic symptom factor was statistically significant in both age and sex variables. The study suggested that they should give a special attention to solve the old people's stress because stress was closely related to residents age.
Anxiety ; Depression ; Factor Analysis, Statistical ; Female ; Gwangju ; Humans ; Jeollanam-do ; Male ; Mass Screening* ; Middle Aged ; Surveys and Questionnaires*

BACKGROUND: Actinic granuloma is an annular inflammatory reaction that develops in skin that has had long-term sun-exposure. OBJECTIVES: The purposes of this study were aimed to characterize the clinical and histopathologic features of actinic granuloma. METHODS: Examinations were performed on eight patients with actinic granuloma regarding the age, sex, duration, clinical morphology, distribution, associated diseases, and treatment and course. Histo-pathologic studies of ten specimens obtained from eight patients were performed with special stains, such as Verhoeff-van Gieson, Gomori-Methenamin silver and alcian blue.
Actins* ; Alcian Blue ; Coloring Agents ; Granuloma* ; Humans ; Silver ; Skin

Infection-induced panniculitis develops either through direct inoculation or as a manifestation of sepsis. However, it has rarely been considered as a disease entity within broader context of panniculitis. Moreover, panniculitis associated with a cardiac abscess without the evidence of sepsis has not been reported. We describe a case of infection-induced panniculitis associated with a cardiac abscess. We suggest that infection should be considered as a potentially important etiology of panniculitis, especially in the case of immunosuppression, and in such a case, meticulous efforts should be done to find the focus of infection.
Abscess* ; Immunosuppression ; Panniculitis* ; Sepsis

Severe skin reactions complicating tumor necrosis factor-alpha (TNF-α) antagonist therapy were somewhat reported in adults. We report a case of 24-month-old boy with refractory Kawasaki disease who developed toxic epidermal necrolysis (TEN) after one dose of 5mg/kg infliximab. The patient responded to intravenous hydrocortisone and was able to discharge without any other serious complications. The clinicians should be aware of the potential for severe skin reactions from the use of TNF-α antagonists in children.

Purpose: This study was done to investigate knowledge of intravenous practice for infection prevention and compliance, empowerment, and organizational culture awareness regarding infection control, and to identify influencing effects regarding compliance with intravenous practice for infection prevention among nurses working in small and medium-sized hospitals. Methods: A cross-sectional descriptive survey was conducted with a sample of 136 nurses working in small and medium-sized hospitals. Data were collected using self-administered questionnaires. For data analysis, descriptive statistics, independent t-tests, one-way ANOVA, Pearson correlations and a stepwise multiple regression were performed using IBM SPSS 23.0. Results: There was a significant correlation between compliance with intravenous practice for infection prevention and knowledge (r=.34, p<.001), and between compliance with intravenous practice for infection prevention and organizational culture awareness of infection control (r=.41, p<.001). Moreover, the factors influencing compliance with intravenous practice for infection prevention were organizational culture awareness of infection control (β=.35, p<.001) and knowledge of intravenous practice for infection prevention (β=.27, p=.001). These variables explained 22.7% of compliance with intravenous practice for infection prevention. Conclusion It is necessary to an organizational culture that emphasizes infection prevention through regular monitoring and feedback and to develop regular education and training programs based on current guidelines.

Severe skin reactions complicating tumor necrosis factor-alpha (TNF-α) antagonist therapy were somewhat reported in adults. We report a case of 24-month-old boy with refractory Kawasaki disease who developed toxic epidermal necrolysis (TEN) after one dose of 5mg/kg infliximab. The patient responded to intravenous hydrocortisone and was able to discharge without any other serious complications. The clinicians should be aware of the potential for severe skin reactions from the use of TNF-α antagonists in children.

Purpose: This study investigated patient safety culture, safety knowledge, incident reporting attitude, and safety nursing activities, and determined the factors influencing nurses’ safety nursing activities at a nationally designated infectious disease hospital. Methods: A cross-sectional descriptive survey was conducted with 169 nurses. Data analysis, including descriptive statistics, independent t-tests, one-way ANOVA, Pearson’s correlations, and hierarchical multiple regression analysis, were performed using SPSS 26.0. Results: Factors influencing safety nursing activities included patient safety culture (β=.26, t=2.39, p=.018), safety knowledge (β=.25, t=2.67, p=.009), and mild severity (β=.17, t=2.52, p=.013). These variables explained 31.0% of the safety nursing activities. Conclusion Therefore, it is necessary to establish an organizational culture that emphasizes patient safety by establishing safety management regulations for quarantined patients and provision of education on patient safety for employees to empower them to respond to emerging infectious diseases. Additionally, it is essential to operate given the patient’s severity and to increase knowledge about patient safety through regular education based on quarantine facilities and environmental management regulations.