1.Video-assisted thoracic surgery versus open thoracotomy for non-small cell lung cancer: Systematic review of matched case control studies
Sundui-Yanjmaa L ; Tuvshinbayar E ; Nyamaa D ; Ganzorig B ; Ganbat O ; Orgilmaa R
Innovation 2020;14(2):56-61
Introduction:
The introduction of minimally invasive surgery has revolutionized multiple
disciplines of surgical practice.
Objectives:
This meta-analysis of matched case control studies aimed to compare the
perioperative outcomes of video-assisted thoracic surgery (VATS) with open thoracotomy for
patients with early-stage non-small cell lung cancer (NSCLC).
Methods:
We searched from PubMed and Embase electronic database and revealed seven
relevant studies. Endpoints included perioperative mortality and morbidity, postoperative
complications and duration of hospitalization. Two investigators (L.S and D.N) independently
reviewed each retrieved article. The values of RR and 95% CI were estimated. We used the fixed
and random-effects models to estimate the size of the treatment benefit.
Results:
Results indicate that perioperative mortality was similar between VATS and open
thoracotomy (RR-0.62(95%CI 0.39-0.98). However, patients who underwent VATS were found to
have fewer overall complications (RR-0.68(95%CI 0.59-0.78), and patients who underwent VATS
had a significantly shorter length of hospitalization compared with those who underwent open
thoracotomy (MD= -2.98(95%CI-4.09:-1.87)).
Conclusions
The present meta-analysis demonstrated superior perioperative outcomes for
patients who underwent VATS, including overall complication rates and duration of hospitalization.
Therefore, our study suggests that VATS should be performed widely to treat patients with lung
cancer in the future.