To know wheter the injury of the ligament may induce the meniscal tear, we statistically analyzed the incidence of meniscal tear with χ2 in cases of fresh and old(more than 3 months since injury) ligament injury in 419 joints of 407 adults who had been treated during the time between early 1984 and the end of 1992 in St. Mary's Hospital. The results were as follows: 1. The meniscal tear occurred more frequently in old ligament tear(44/70, 62.9%) than in fresh ligament tear(7/26, 26.9%) in cases of isolated ACL tear(P=0.062). 2. There was no significant difference between the old(10/34, 29.4%) and the fresh tear(24/96, 25.0%) in the combined ACL tear(P=0.615). 3. Overall ACL tear patients showed higher incidence of meniscal tear in the old ligament tear(54/1-4, 51.9%) than in the fresh ligament tear(31/122, 25.4%)(P=0.000). 4. The frequency of meniscal tear was very low in the isolated PCL tear(fresh tear: 0/14, old tear:1/17, 5.9%). In cases of combined PCL tear the incidence was rather higher in the fresh tear(11/33, 33.3%) than in the old tear(2/30, 6.7%)(P=0.015). 5. Overall PCL tear patients showed higher incidence of meniscal tear in the fresh ligament tear(11/47, 23.4%) than in the old ligament tear(3/47, 6.4%)(P=0.020). 6. The meniscal tear occurred more frequently in the ACL tear than in the PCL tear in both isolated(ACL : 85/96, 53.1%, PCL : 1/31, 3.2%) and overall ACL or PLC tear group(ACL : 85/226, 37.6%, PCL : 14/16.7%)(P=0.000). 7. The meniscal tear occurred less frequently in the isolated clootgeral ligament tear(9/94, 9.6%) than in the isolated cruciate ligament tear(52/127, 40.9%)(P=0.000). 8. The incidence of tear between the medial and the lateral meniscus showed no statistically significantly difference(P=0.215). From these results it would be suggested that the ACL tear, especially isolated tear may induce meniscal tear. On the other hand there was no statistically significant relationship between the incidence of meniscal tear and those of either PCL tear or collateral ligament tear.
Adult ; Collateral Ligaments ; Hand ; Humans ; Incidence ; Joints ; Ligaments ; Menisci, Tibial ; Tears

The objective of this study was to explore the psychosocial factors such as life events, coping styles and family relationships in middle-aged depressed women. This study was designed to compare how different variables relate to depression in two different test groups: a depressed patient group and a normal group. The Beck Depression Inventory(BDI), The Ways of Coping Checklist, Interpersonal Support Evaluation List(ISEL), Family Environment Scale were administered to 116 depressed patients and 113 normal persons between the ages of 35 and 64. The results were as follows 1) The highest stress was marital stress(n=42, 36.2%) in patient group and family stress(n=44, 38.9%) in normal group, respectively. 2) There were significant differences between patient group and normal group in BDI scores (t=15.94, p<.0001), lift events(t=4.73, p<.0001), active coping(t=6.29, p<.0001), social support(t=7.20, p<.0001), and family relationship(t=5.75, p<.0001) except for passive coping(t=0.93, p=.35). 3) In depressed patient group, BDI scores had a significantly positive correlation with the scores of the life event(r=.24, p<.01) and negative correlation with active coping(r= -.22, p<01), social support(r=-.35, p<.001) and family relationships(r=-.30, p<.001). 4) In depressed patient group, multiple regression analysis showed that social support(12.3%, beta=-.281, T=-3.162, P=.002), lift events(5.1%, beta=.279, T=3.195, F=.002), and active coping(3.5%, beta=-.204, T=-2.225, F=.028) had predictability on the BDI scores and the total predictability was 20.9%. 5) Stress experienced in family relationships were highest in life events and there was a lack of consistency(in the BDI scores ol the coping styles). Social support was the most important factor and there were no significant differences between the two groups in family relationships.
Checklist ; Depression ; Family Relations* ; Female ; Humans ; Psychology

PURPOSE: This study was aimed to evaluate the efficacy of an eye-tracking system, in terms of the amount of decentration. Comparison was made between two LASIK groups operated with and without the use of eye-tracking system. METHODS: An eye-tracking system was used in 41 eyes(Group 1) and patient fixation alone without an eye-tracking system in 41 eyes(Group 2). Corneal topography(Humphrey ATLAS(TM) Corneal Topography System; Zeiss Humphrey Systems, Dublin, California, U.S.A.) was performed before surgery and 3 months postoperatively. The amount of ablation decentration was measured on the difference map obtained from the axial map. RESULTS: The mean +/-SD of decentration was 0.38 +/-0.23 mm in group 1, and 0.49 +/-0.24 mm in group 2(p=0.047). The amount of decentration was graded as follows: grade I(<0.5 mm); Grade II(0.5~1.0 mm); Grade III(>1.0 mm). Grade I, there was a significantly less decentration in group 1(p=0.037). For grade II, however, there was no significant difference between the two groups(p=0.766). CONCLUSIONS: Using eye-tracking system alone may not be effective in decreasing moderate decentration. Good fixation of the patients seemed to be as effective as an eye tracking system in achieving good ablation centration.
California ; Corneal Topography ; Humans ; Keratomileusis, Laser In Situ*

No abstract available.

No abstract available.
Mandibular Condyle

Objective: To investigate the dental phenotypes and treatment modalities (TxMod) in Korean patients with Parry–Romberg syndrome (PRS) using longitudinal data. Methods: The samples consisted of 10 PRS patients, who were treated and/or followed-up at Seoul National University Dental Hospital between 1998 and 2019. Using a novel PRS severity index based on the numbers of the atrophy-involved area and asymmetry-involved item, we classified them into mild (n = 3), moderate (n = 2), and severe (n = 5). Dental phenotypes, including congenitally missing tooth (Con-Missing-Tooth), microdontia, tooth with short root (Short-Root), tooth with dilacerated root, and delayed eruption/impacted tooth, were investigated along with Tx-Mod. Results: The side of occurrence of all dental phenotypes showed 100% concordance with the side of PRS involvement. The most two common dental phenotypes were Con-MissingTooth and Short-Root (n = 29 and n = 17 in six patients). The sums of the average number of Con-Missing-Tooth and Short-Root increased from mild PRS to moderate PRS and severe PRS cases (1.0, 6.0, and 6.2). In terms of TxMod, growth observation due to mild atrophy, fixed orthodontic treatment, and grafting were used for mild PRS cases. Tx-Mod for moderate PRS cases involved growth observation for surgery due to an early age at the initial visit. For severe PRS cases, diverse Tx-Mod combinations including unilateral functional appliance, fixed orthodontic treatment, growth observation, grafting, and orthognathic surgery were used. Conclusions The novel PRS severity index may be useful to provide primary data for individualized diagnosis and treatment planning for PRS patients.

Allergic response to common environmental agents has been regarded as a main pathogenetic mechanism of bronchial asthma. However, allergic sensitization (atopy) can not be detected in a siginificant number of adult asthmatic patients. The etiology of nonatopic asthma has not yet been defined. To evaluate the possible involvement of autoimmune response against bronchial mucosa in the pathogenesis of nonatopic asthma, we performed indirect immunofluorescence staining of fresh frozen human bronchial mucosa tissue using serum samples from patients with atopic and nonatopic asthma, healthy controls, and patients with systemic lupus erythematosus. On immunostaining, circulating IgG autoantibodies against bronchial mucosa were detected in 2 (9.1%) of 22 patients with nonatopic asthma and in none of 22 patients with atopic asthma and of 22 healthy controls. IgG autoantibodies from the two patients with nonatopic asthma predominantly stained the cytoplasmic membrane of basal cells in bronchial epithelium. Serum samples from 10 patients with systemic lupus erythematosus immunostained the nucleus of epithelial cells in whole layer of bronchial epithelium. This study showed the presence of circulating IgG autoantibodies against the bronchial epithelial cell in a small portion of patients with nonatopic asthma. Further studies may be necessary to evaluate the possible involvement of autoimmune mechanism in the pathogenesis of nonatopic asthma.
Asthma/immunology* ; Autoantibodies/immunology* ; Autoantibodies/blood ; Bronchi/immunology* ; Epithelial Cells/immunology ; Human ; Immunity, Mucosal/immunology ; Respiratory Mucosa/immunology*

The purpose of this study was to investigate a possibility of chronic or intermittent bacteremia in patients undergoing orthodontic treatment with fixed orthodontic appliance. Orthodontic patients who had been injured by orthodontic appliances and/or suffered from gingivitis were selected. They had not taken any antibiotics for 1 month. The number of subjects were 21 including 7 males and 14 females. Blood samples of the subjects were cultured and, IgG, IgA and IgM levels in the serum were quantified. The author found following results. 1. No bacterial growth was found in 7-day culture of all the samples. 2. The immunoglobulin levels in serum were confined in normal range. 3. This study could not deny the possibility of transient bacteremia episode undergoing orthodontic treatment.
Anti-Bacterial Agents ; Bacteremia* ; Female ; Gingivitis ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Immunoglobulins ; Male ; Orthodontic Appliances ; Reference Values

OBJECTIVES: The protective effects of estrogen against the development of schizophrenia have been investigated in various perspectives. Previous studies showed patients with earlier age of menarche had later onset of schizophrenia and less frequent admissions. This study was performed to evaluate the effect of the age of menarche on subsequent courses including hospitalizations, suicidal attempts, physical harm to others, and psychotic symptoms in women with schizophrenia. METHODS: Self-report menarche age, onset of psychotic symptoms, and clinical status were collected in a sample of 108 premenopausal women with the diagnosis of schizophrenia. RESULTS: There was significant correlation between the age of menarche and the frequency of admissions (r=.321, p=.006). Also, patients with history of physical harms to others showed later age of menarche than those without (t=2.025, df= 106, p=.045). CONCLUSION: In women with schizophrenia, the age of onset of menarche affects subsequent courses indicated by frequency of admissions and violent behaviors. It is suggested that identifying the age of menarche might be helpful to predict the courses in women with schizophrenia. Further investigations regarding the relationship between estrogen and the courses of schizophrenia in women are needed.
Age of Onset ; Diagnosis ; Estrogens ; Female ; Hospitalization ; Humans ; Menarche* ; Schizophrenia*

OBJECTIVES: The protective effects of estrogen against the development of schizophrenia have been investigated in various perspectives. Previous studies showed patients with earlier age of menarche had later onset of schizophrenia and less frequent admissions. This study was performed to evaluate the effect of the age of menarche on subsequent courses including hospitalizations, suicidal attempts, physical harm to others, and psychotic symptoms in women with schizophrenia. METHODS: Self-report menarche age, onset of psychotic symptoms, and clinical status were collected in a sample of 108 premenopausal women with the diagnosis of schizophrenia. RESULTS: There was significant correlation between the age of menarche and the frequency of admissions (r=.321, p=.006). Also, patients with history of physical harms to others showed later age of menarche than those without (t=2.025, df= 106, p=.045). CONCLUSION: In women with schizophrenia, the age of onset of menarche affects subsequent courses indicated by frequency of admissions and violent behaviors. It is suggested that identifying the age of menarche might be helpful to predict the courses in women with schizophrenia. Further investigations regarding the relationship between estrogen and the courses of schizophrenia in women are needed.
Age of Onset ; Diagnosis ; Estrogens ; Female ; Hospitalization ; Humans ; Menarche* ; Schizophrenia*