1.Test methods of visual alarm signal for medical alarm systems.
Chinese Journal of Medical Instrumentation 2014;38(3):219-221
This paper introduces several test methods of characteristics of alarm indicator lights which can be used in the medical alarm system to verify the compliance of YY 0709-2009. These methods include the direct measurement of the pulse current supply of the alarm signals, image analysing of a video and reception by photoelectric sensor. After the comparation of the advantages and disadvantages among these methods, this paper proposes a new method of signal reception. This method which used a silicon photocell as the sensor with light filter in its front, and amplified circuit in the output end then used an oscillograph as the reviewer, has resolved the testing difficulties of the flashing signal simulating by LCD, and can be applied to test the alarm indicator lights in any medical electrical equipment.
Clinical Alarms
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Equipment Design
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Signal Processing, Computer-Assisted
2.Wireless human body communication technology.
Journal of Biomedical Engineering 2014;31(6):1389-1393
The Wireless Body Area Network (WBAN) is a key part of the wearable monitoring technologies, which has many communication technologies to choose from, like Bluetooth, ZigBee, Ultra Wideband, and Wireless Human Body Communication (WHBC). As for the WHBC developed in recent years, it is worthy to be further studied. The WHBC has a strong momentum of growth and a natural advantage in the formation of WBAN. In this paper, we first briefly describe the technical background of WHBC, then introduce theoretical model of human-channel communication and digital transmission machine based on human channel. And finally we analyze various of the interference of the WHBC and show the AFH (Adaptive Frequency Hopping) technology which can effectively deal with the interference.
Computer Communication Networks
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Humans
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Models, Theoretical
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Wireless Technology
3.Influence of early rehabilitative exercise in patients with myocardial infarction
Chinese Journal of Tissue Engineering Research 2006;10(24):164-166
BACKGROUND: In treatment of traditional acute myocardial infarction,patients were required to lie on the bed resting for 1-4 weeks. Recently research showed that early rehabilitation exercise in myocardial infarction patients could ameliorate the reservation of cardio function, increase exercise tolerance, augment myocardial hemoperfusion, decrease myocardial ischemia and reduce the anxious and depressive emotion.OBJECTIVE: To observe the influence of early rehabilitation movement on activity of daily living, duration of hospital stay, mean hospitalized cost,incidence rate of arrhythmia and recurrence rate of myocardial infarction in two years.DESIGN: Non-randomized concurrent control analysis.SETTING: Beijing Tiantan Hospital.PARTICIPANTS: Totally 80 patients with acute myocardial infarction,who were hospitalized at Department of Circulation, Beijing Tiantan Hospital from August 2002 to October 2003, were enrolled. They were all at most 70 years old with stable pathogenetic condition. Left ventricular ejection fraction (LVEF) was over 35%. They were not combined with severe hypertension, severe pulmonary disease, nerve and disease of locomotor system.METHODS: The selected cases based on patients' will were assigned into two groups (n=40), ①early rehabilitation group: They were treated with routine drugs, absolute bed rest for 24 hours. At day 2 the head stock was rose about 30°to do passive exercise of extremity joint. At days 3-5, the patients sat on the bed, 3 times per day. At days 6-7,the patients stood at bedside, 3 times per day. At days 8-9, the patients moved joints of extremities at bedside and walked slowly in room. At days 10-14, the patients exercised walking. If there were angina pectoris attacks, serious cardiac arrhythmias or dyspneic respiration, etc., the movement should be suspended or the exercise intensity came back to that in the former stage. ②Absolute bed rest group: The patients were absolute bed rest, and only treated with routine drug without any rehabilitation training.MAIN OUTCOME MEASURES: Barthel index (full mark was 100 points, and < 60 points represented unable self-care) was used to assess activity of daily living of patients. Mean duration of hospital stay, mean hospitalized cost, incidence rate of arrhythmia and recurrence rate of my ocardial infarction in two years were compared between the two groups.RESULTS: A total of 80 patients that conducted the therapy and follow up were involved in the result analysis. ①Mean duration of hospital stay and mean hospitalized cost in the early rehabilitation group were less than those in the absolute bed rest group (17.1 days vs 24.5 days; 9 021.23 yuan vs 12 383.45 yuan; P < 0.05). ②Barthel index: There was insignificant difference before treatment between the two groups. It was significantly higher in the early rehabilitation group than that in the absolute bed rest group before discharge (81.43±13.57,70.68±11.48,P < 0.05). ③Six and seven patients had the onset of arrhythmia in the early rehabilitation group and the absolute bed rest group, respectively. ④Follow-up observation was performed for two years. The recurrence rate of myocardial infarction in the early rehabilitation group (5% ,2/40) was obviously lower than that in the absolute bed rest group (22 %,9/40).CONCLUSION: The early rehabilitation training is of benefit to elevate activity of daily living of myocardial infarction patients, reduce mean duration of hospital stay and mean hospitalized cost and decrease recurrence rate.
4.The clinical value of Tei index in the evaluation of left ventricular function of diabetic patients with normal LVEF
Chinese Journal of Primary Medicine and Pharmacy 2013;20(22):3388-3390
Objective To observe the value of myocardial performance index (Tei index) in evaluating the left ventricular function in diabetic patients with normal left ventricular ejection fraction (LVEF),and to investigate its correlation with plasma N-terminal pro-brain natriuretic peptide (NT-proBNP).Methods 96 diabetic patients with normal LVEF were selected as the observation group,50 healthy persons were selected as control group.Left ventricular Tei index was measured by color Doppler ultrasound.The plasma NT-proBNP was detected.Results The Tei index,plasma level of NT-proBNP of the observation group were (0.49 ± 0.11),(397.6 ± 39.4) ng/L,those of the control group were (0.32 ± 0.07),(101.2 ± 18.4) ng/L,the differences between the two groups were statistically significant(t =11.357,1.992,all P < 0.05).There was significant positive correlation between Tei index and plasma NT-proBNP in the observation group(r =0.661,P < 0.05).Conclusion Combined determination of Tei index and plasma NT-proBNP can detect early myocardial damage in patients with diabetes mellitus.
5.Effect of one-time exhaustive exercise on individual' s mood states
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(10):929-931
Objective To study the changes of the mood states at different time point of one-time exhaustive exercise.Methods16 participants were tested by POMS at the moments before,at,after recovery and after recovery 20 min of one-time exhaustive exercise.Results The scores of the 7 subscales got by 4 measures were used for one-way repeated measures analysis of variance.The results were showed that tension subscale scores (F (3.45) =0.335,P>0.05,ES =0.022),anger subscale scores (F(3.45) =3.683,P>0.05,ES =0.197),fatigue subscale scores (F(3.45 =0.863,P>0.05,ES =0.054),depression subscale scores (F(3.45) =1.905,P> 0.05,ES =0.113 ),confusion subscale scores (F( 3.45) =0.601,P > 0.05,ES =0.039 ) and self-esteem subscale scores (F(3.45) =2.804,P > 0.05,ES =0.157 ) had no significant differences,but vigor subscale scores increased significantly (F(3.45) =8.778,P < 0.01,ES =0.369).Conclusion One-time exhaustive exercises enhanced individual' s positive mood states.
6.Approaches to improving the teaching quality of orthopedics in digital and network environment
Chinese Journal of Medical Education Research 2017;16(2):166-169
Based on the digital and network environment, this paper analyzes the problems existing in the teaching of traditional orthopedics in medical colleges and universities, including single teaching form, neglecting the students' practical skills and the phenomenon of students' poor learning initiative. It points out that the orthopedics teaching under the digital and network environment should be integrated through interactive teaching, multimedia teaching, WeChat network teaching, simulation teaching, practice teaching and other teaching forms and should pay attention to the reasonable use of teaching methods, make clear teachers and students' subject status, pay attention to students' learning ability training, so as to improve the teaching quality of orthopedics in medical colleges.
7.Analysis of human intestinal helminth infections in Yancheng City,Jiangsu Province from 2006 to 2015
Chinese Journal of Schistosomiasis Control 2016;28(6):660-663
Objective To investigate the epidemiological trend of human intestinal helminth infections in Yancheng City,Ji?angsu Province from 2006 to 2015,so as to provide the evidence for formulating further control strategies. Methods The sur?veillance data of human intestinal helminth infections were collected and analyzed in Yancheng City from 2006 to 2015. Re?sults From 2006 to 2015,110 746 person?times of residents in Yancheng City were surveyed in Yancheng City,and 1 732 samples were positive of human intestinal helminth infections. The infection rate of human intestinal helminthes was highest in 2006[4.59%(410/8 941)],and lowest in 2013[0.19%(23/12 165)]. The infection rate of human intestinal helminthes was significantly decreased over time(χ2=27.78,P<0.001). The human infection rates of Ascaris lumbricoides,hook worm and Trichuris trichura were all decreased over time(Z=-27.75,-22.23 and-16.17,all P<0.001)from 2006 to 2015,with the re?duction rates of 96.57%,92.31%and 96.47%,respectively. The average EPG of A. lumbricoides,hook worm and T. trichura were 2 534,360 and 154 respectively,and 1 694(97.81%)cases were light infections. Totally 1 174 cases of Enterobius vermic?ularis were found in children under 12 years old,and the cases were decreased over time(χ2 =12.46,P<0.001). Conclu?sions The infection rate of human intestinal helminthes in Yancheng City decreases over time from 2006 to 2015,and the con?trol work is effective. The control work of focus groups and environmental management and health education should be strength?ened in the future.
8.Preliminary research of Er:YAG laser used for pulpotomy of Beagle dogs
Journal of Peking University(Health Sciences) 2016;48(4):714-719
Objective:To investigate the effects of erbium:yttrium aluminium garnet (Er:YAG)laser irradiation on pulp and formation of dentin bridge.The beagle dogs'coronal pulp is amputated by Er:YAG laser.Methods:In the study,24 premolar teeth of two one-year-old Beagle dogs were used.They were divided into 3 groups:bur group,200 mJ laser group,100 mJ laser group.The coronal pulp were removed by traditional bur or 200 mJ/20 Hz or 100 mJ/20 Hz Er:YAG laser.Then,they were dressed with mineral trioxide aggregate (MTA)and sealed with resin.Clinical,radiological and histological ana-lyses were performed 1 day,2 weeks,4 weeks and 8 weeks after treatment.The mobility and gingiva si-tuation were evaluated for clinical evaluation.Periapical films were used for radiological evaluation.The extracted teeth were preserved in 10% formalin.After decalcification,tissue processing,paraffin embed-ding,serial sectioning at 5 μm thickness,staining (Hematoxylin and Eosin,HE),the samples were as-sessed by an independent observer for calcified bridge formation and radicular pulp inflammation.The mean thickness of dental bridge was measured if there was complete dental bridge.Results:Clinical evaluation:there were no signs of fistula or mobility or any abnormal symptoms in Er:YAG laser groups and bur group during the observation period.Radiological evaluation:there were no signs of widened pe-riodontal ligament or root absorption or periapical radiolucency in Er:YAG laser groups and bur group. Histological evaluation:there was no severe inflammation reaction in 200 mJ/20 Hz,100 mJ/20 Hz Er:YAG laser groups and bur group 1 day,2 weeks,4 weeks,8 weeks post-operation in Hematoxylin and Eosin staining.A complete dentin bridge could be observed in 200 mJ/20 Hz,100 mJ/20 Hz Er:YAG laser groups,while no complete dentin bridge in bur group 2 weeks post-operation.Complete dental bridge could be observed in each group 4 and 8 weeks post-operation.The mean thickness of dental bridge 4 weeks post-operation in 200 mJ laser group was 77 μm,100 mJ laser group 87 μm,and bur group 101 μm,and 8 weeks post-operation in 200 mJ laser group was 222 μm,100 mJ laser group 160μm,and bur group 152 μm.Conclusion:The 200 mJ/20 Hz and 100 mJ/20 Hz Er:YAG laser pulpoto-mies show no harm to radicular pulp and can promote the formation of dentin bridge.
9.Proton pump inhibitors and the pathophysiological mechanism of the risk of gastric cancer and its clinical researchs progress
Journal of Chinese Physician 2016;18(8):1268-1271
Proton pump inhibitors as a kind of acid drug are widely used in clinical.However,it is overused all over the world although generally safe and effective.Studies have shown the uncertainty of potential long-term adverse effects,especially the contact with the mechanism of gastric cancer.Clinicians should pay more attention to the potential carcinogenic risk of long-term proton pump inhibitors in treatment.The mechanism of pathophysiology and the clinical researches of proton pump inhibitor-induced gastric neuroendocrine tumors,gastric carcinoma,and gastric cardia cancers are summarized as follows.
10.Association of vitamin D level and severity of diabetic retinopathy and maculopathy
Chinese Journal of Biochemical Pharmaceutics 2016;36(8):141-144
Objective To discuss the association between vitamin D level and the severity of diabetic retinopathy and maculopathy in type 2 diabetes mellitus.Methods 657 patients with type 2 diabetic patients were included in our study and classified into four groups according to their severity of diabetic retinopathy:the non-diabetic retinopathy group(NDR group, n=257) ,the background diabetic retinopathy group(BDR group, n=243), the preproliferative diabetic retinopathy group(PPDR group, n=135) and the proliferative diabetic retinopathy group(PDR group, n=22).The patients were divided into maculopathy(n=563) and non-maculopathy(n=94).Characteristics data were recorded and disease duration, body mass index, blood pressure and other lipid makers were measured and compared among groups.Results Among four diabetic retinopathy groups, 25(OH)D was statistically different (P <0.05), however, compared to diabetic maculopathy group, the level of 25(OH)D in non-maculopathy group was not statistically different.Logistic regression showed that 25(OH)D was significantly associated with the severity ofdiabetic retinopathy(P<0.05), while not with diabetic maculopathy.Conclusion The level of 25 ( OH ) D is closely associated with the severity ofdiabetic retinopathy in patients with type 2 diabetes mellitus, and it might be an important predictor for the severity of diabetic retinopathy.