No abstract available.
Humans ; Lung Diseases*

No abstract available.
Humans ; Lung Diseases*

No abstract available.
Classification* ; Lung Diseases*

PURPOSE: The purpose of this study was to describe hospital nurses' knowledge and beliefs about hand hygiene and to identify the relationships between knowledge and beliefs. METHODS: Data were collected from 232 nurses working in four university hospitals and were analyzed using SPSS/WIN 20.0 program. RESULTS: The mean score of knowledge of hand hygiene was 8.1. The mean scores of behavioral, normative, and control belief about hand hygiene were 2.3, 2.5, and -0.7, respectively. Knowledge was correlated with educational level (p=.013) and experience of hand hygiene campaign (p=.018). The behavioral belief was correlated with age (p<.001) and career (p=.002). The normative belief was correlated with work department (p=.007). The control belief was correlated with educational level (p=.043) and experience of being monitored on hand hygiene (p=.010). The subjects who believed that head nurses, charge nurses, and colleagues practiced better hand hygiene had higher behavioral and normative belief scores than those who did not. There were no significant relationships between knowledge and beliefs. CONCLUSION: There is a need to improve knowledge of hand hygiene in hospital nurses. This study provides information for developing strategies to strengthen beliefs about hand hygiene.
Hand ; Hand Hygiene ; Hospitals, University ; Infection Control ; Nursing, Supervisory

No abstract available.

No abstract available.
Drug Therapy* ; Lung Neoplasms* ; Lung*

BACKGROUND: Interleukin-18 (IL-18) is one of the principal inducers of interferon-gamma (IFN-gamma) in lymphocytes. MATERIALS AND METHODS: The effect of IL-18 on the expression of chemokine IP-10(CXCL10) mRNA in C57BL/6 mouse peritoneal macrophages was studied by using Northern blot analysis, enzyme linked immunosobent assay and electrophoretic mobility shift assay. RESULTS: IL-18 was determined to exert no direct effect on the expression of IP-10(CXCL10) mRNA. However, IL-18 pretreatment was determined to play a cooperative role in the synergistic induction of LPS-induced IP-10(CXCL10) mRNA expression. The effect associated with IL-18 pretreatment with regard to the synergistic induction of LPS-induced IP-10 (CXCL10) mRNA expression was detected after 16 hr of IL-18 pretreatment, administered prior to LPS stimulation. The pattern of NF-kB binding activity during IL-18 pretreatment with LPS stimulation was found to coincide with the expression of IP-10(CXCL10) mRNA. CONCLUSION: Although IL-18 alone exerts no direct effect on the expression of chemokine IP-10(CXCL10), a definite period of IL-18 pretreatment induces the synergistic expression of LPS-induced IP-10(CXCL10) mRNA. NF-kB activation is a component of this synergistic effect of IL-18 pretreatment. These results provide useful information, which may facilitate the elucidation of the action mechanisms underlying IL-18 effect on the expression of IP-10(CXCL10) mRNA.
Animals ; Blotting, Northern ; Electrophoretic Mobility Shift Assay ; Interferon-gamma ; Interleukin-18* ; Lymphocytes ; Macrophages, Peritoneal ; Mice ; NF-kappa B ; RNA, Messenger* ; Up-Regulation*

We herein describe two cases of sudoriparous angioma consisting of increased number of eccrine sweat glands associated with angiomatous vascular channels. Case 1 is a 16 year-old girl developing two, painful and tender cavernous hemangiomas which sweated whenever compressed. These were located on her left gluteal area since early childhood. The biopsy specimen revealed an increased number of cystically dilated eccrine glands in the mid-dermis in addition to vascular components in the lower dermis. Case 2 is a five year-old girl manifesting non-tender, slightly hyperhidrotic nevus flammeus-like eruption on her left suprapopliteal area since birth, the biapsy apecimen of which revealed an increased number of eccrine glands admixed with capillary hemangioma in the mid-dermis.
Adolescent ; Biopsy ; Dermis ; Eccrine Glands ; Female ; Hemangioma* ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Humans ; Nevus ; Parturition ; Sweat ; Sweat Glands

Leiomyosarcoma of small intestine is an uncommon tumor, comprising less than 20 percent of all primary malignant tumors of small intestine. Duodenal leiomyosarcoma is rare disease which amount to about 20 percent of all small bowel malignancy but potentially curable tumors often diagnosed at an advanced age, so its five-year survival following resection approximates 50% in reported series. Recently, several cases of leiomyosarcomas of duodenum were diagnosed by hypotonic duodenograhy in Korea. We experienced a woman with duodenal leiomyosarcoma that was diagnosed by endoscopic duodenal biopsy and received currative resection of the tumor(Whipple's operation). We report the case with review of the literatures.
Biopsy ; Duodenum ; Endoscopy ; Female ; Humans ; Intestine, Small ; Korea ; Leiomyosarcoma* ; Rare Diseases

Coxiella burnetii(C. burneii)was first recognized as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatosplenomegaly, lymphadenopathy, leukemia, lymphoma, and immunodeficiency and 14 persons who contacted the Q fever patients. The patient's sera were tested for antibodies specific for C. burnetii, using indirct fluorescent antibody techniques (IFA). 1) We serologically confirmed 23 C. burnetii infection. The 23 children with Q fever ranged in age from 0 to 15 years, with mean age of 4 years 11 months. Seventeen were boys and 6 were girls. 2) Characteristic symptoms and signs were fever (9/12 cases), rash (8/14 cases), hepatosplenomegaly (8/8 cases)and lymphadenopathy (14/27 cases). Five cases among 14 asymptomatic cases who contacted Q fever patients showed positive IFA test. One suffered from irregular uterine contraction, 4 weeks after contact with a Q fever patient. 3) There were no history of exposure to domestic animal carriers or contaminated dust, or drinking raw milk except one family. Three attending doctors and her father infected by a patient with Q fever. These suggested the person to person transmission of Q fever in a family and house staffs infected by a patient of Q fever. 4) Q fever (9 cases), acute lymphoblastic leukemia (2 cases), acute myelomonocytic leukemia (1 case), hairy cell leukemia (1case), Kawasaki disease (4 cases) and congenital dyserythropoietic anemia (1 case) showed positive IFA test. 5) Of 9 cases who suffered from lnly Q fever, 7 cases were confirmed hairy cell formation in their peripheral blood. One case was diagnosed as hairy cell leukemia after bone marrow study. Of 7 cases who showed hairy cells, all had hepatomegaly, 6 cases had lymphedenopathy and 5 cases showed splenomegaly. All except 1 case who was not followed cured after treatment. 6) We treated Q fever patients with rifampin and/or ciprofloxacin, and/or tetracyclin (over 8 year-old of age)for 2-4 weeks. One 25 month-old patient with hairy cell leukemia was treated with rifampin, ciprofloxacin and tetracyclin for 4 weeks, and rifampin for 8 months. A pregnant patient was administered with rifampin, and treated with rifampin and ciprofloxacin after delivery. We gave rifampin in one nweborn baby. In conclusion, we suggest that Q fever should be considered in the differential diagnosis of patients with FUO, hepatosplenomegaly and/or immunodeficiency.
Anemia, Dyserythropoietic, Congenital ; Animals, Domestic ; Antibodies ; Bone Marrow ; Child ; Child, Preschool ; Ciprofloxacin ; Coxiella burnetii* ; Coxiella* ; Diagnosis, Differential ; Drinking ; Dust ; Exanthema ; Fathers ; Female ; Fever ; Fever of Unknown Origin ; Fluorescent Antibody Technique ; Hepatomegaly ; Humans ; Internship and Residency ; Leukemia ; Leukemia, Hairy Cell ; Leukemia, Myelomonocytic, Acute ; Lymphatic Diseases ; Lymphoma ; Milk ; Mucocutaneous Lymph Node Syndrome ; Pneumonia ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Prospective Studies ; Q Fever* ; Rifampin ; Splenomegaly ; Uterine Contraction