1.Factors related to Quality of Life of Patients with Failed Back Surgery Syndrome
Journal of Korean Academy of Fundamental Nursing 2021;28(3):311-319
Purpose:
This study was done to investigate factors related to quality of life of patients with failed back surgery syndrome.
Methods:
One hundred and eighty four patients were recruited from a hospital pain clinic. Data were collected from March 12 to April 9, 2018 using structured questionnaires which included questions about quality of life, hope, and family support. Data analysis was done with descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficient, and stepwise multiple regression analysis with SPSS version 25.0.
Results:
The factors related to quality of life were hope, family support, and frequency of pain. These three factors accounted for 53.1% of the total variance in quality of life.
Conclusion
In order to increase quality of life of patients with failed back surgery syndrome, it is necessary to design intervention programs that effectively manage hope, family support, and frequency of pain.
2.Characterization of Severe Acute Respiratory Syndrome Coronavirus 2Stability in Multiple Water Matrices
Young Jae LEE ; Je Hyoung KIM ; Byeong-Sun CHOI ; Jang-Hoon CHOI ; Young-Il JEONG
Journal of Korean Medical Science 2020;35(36):e330-
The advent of the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates a thorough study of the stability and transmissibility in the environment. We characterized the stability of SARS-CoV-2 in three water matrices: fresh, tap, and seawater. The minimum infective dose of SARS-CoV-2 in Vero cells was confirmed to be 10 3 PFU/mL. The stability of SARS-CoV-2 varied according to the water matrix: infective SARSCoV-2 was undetectable after treatment with fresh water and seawater, but remained detectable for 2 days in tap water, when starting with an initial concentration of 10 4 PFU/mL. When the starting concentration was increased to 10 5 PFU/mL, a similar trend was observed. In addition, viral RNA persisted longer than infectious virus in all water matrices. This study was conducted in stagnant water containing a significantly high titer of virus, thus, human-to-human transmission of SARS-CoV-2 through the actual aquatic environment is expected to be rare.
3.Effect of Korean red ginseng on the levels of serum p24 antigen, ?-microglobulin, and CD4+T cell counts in HIV infected patients treated with AZT(I).
Young Keol CHO ; Young Bong KIM ; Byung Sun CHOI ; Young Sik JANG ; Young Oh SHIN ; Yoo Kyum KIM
Journal of the Korean Society for Microbiology 1993;28(5):409-417
No abstract available.
Cell Count*
;
HIV*
;
Humans
;
Panax*
4.Two Cases of Murine Typhus.
Seung LEE ; Gi Bum SHUR ; Jeung Hoon LEE ; Jang Kyu PARK ; Sun Young KIM
Korean Journal of Dermatology 1989;27(2):211-216
We report two cases of murine typhus diagnosed by indirect immunofluorescent test. The patients showed cardinal symptoms and signs such as fever and chill, general myalgia, intractable headache and typical rash. Laboratory values and histopathologic findings were compatible with murine typhus. The oral administration of doxycycline improved dramatically the clinical manifestations of the two CCLSPS.
Administration, Oral
;
Doxycycline
;
Exanthema
;
Fever
;
Headache Disorders
;
Humans
;
Myalgia
;
Typhus, Endemic Flea-Borne*
5.Genetic Variants of Thromobomodulin Gene as Risk Factors for Myocardial Infarction.
Hyun Young PARK ; Youngmi KIM ; Hyuck Moon KWON ; Sun Ha JEE ; Seung Yeon CHO ; Yangsoo JANG
Korean Circulation Journal 2000;30(6):702-715
Thrombomodulin (TM) is thrombin receptor present on the luminal surface of endothelial cells. Because the thrombin-TM complex acts as an anticoagulant, the functional variants or deficiency of TM may lead to increment of thrombotic tendency. In this study, we screened the genetic variants of the TM gene in patients with myocardial infarction (MI) and analyzed the genotype to elucidate the effects of genetic variations of TM gene on the development of the MI. We screened a promoter region and coding sequence of the TM gene using single strand conformation polymorphism-heteroduplex analysis and identified three common genetic variants: those were TM G-33A, TM Ala455Val, and TM C1922T. The genotype frequencies were investigated in the patients with MI (n=234) and control subjects (n=291) by the method of allele-specific oligomer hybridization. The frequencies of mutant genotypes (TM -33A, TM 455Val, and TM 1922T) were higher in patient group compared to the control subjects in males while there were no significant differences in females. In the multiple logistic regression analysis, TM 455Val and TM 1922T alleles were independent risk factors for MI (OR[95% CI: 1.799[1.125-2.878] p=0.014 and 5.624[1.019-31.025], p=0.048, respectively) in males. However, the genetic variations were not independent risk factors for MI in females. There were significant linkage disequilibriums among three genetic variants. These linkage disequilibriums explain the similar effects of three genetic variants on the development of MI. To investigate the effect of the TM G-33A mutation on TM promoter activity, the two TM promoter constructs (pTM-355 and pTM-125, bearing TM -33G or TM -33A) containing of firefly luciferase gene were transfected into HepG2, BAE, and CHO cells. The promoter activities were higher in the promoter constructs with TM -33G compared to the constructs with TM -33A in pTM-355. These results suggest the possibility of the positive predisposing effect of TM -33A allele on MI in males. The functional study for TM Ala455Val and TM C1922T should be followed to elucidate the genotype effects of these mutations on the development of MI. In this study, we identified three genetic variants of TM gene and showed the significant associations between genetic variants and MI in males. These results proposed that TM gene is an attractive candidate for genetic risk factor for MI in Koreans.
Alleles
;
Animals
;
CHO Cells
;
Clinical Coding
;
Cricetinae
;
Endothelial Cells
;
Female
;
Fireflies
;
Genetic Variation
;
Genotype
;
Humans
;
Linkage Disequilibrium
;
Logistic Models
;
Luciferases
;
Male
;
Myocardial Infarction*
;
Phenobarbital
;
Promoter Regions, Genetic
;
Receptors, Thrombin
;
Risk Factors*
;
Thrombomodulin
6.Two cases of nasopharyngeal carcinoma in children.
Tae Sun HA ; Chul Ho JANG ; Hee Young SHIN ; Hyo Seop AHN
Journal of the Korean Pediatric Society 1991;34(4):587-593
No abstract available.
Child*
;
Drug Therapy
;
Humans
;
Radiotherapy
7.A case of homocystinuria.
Kang Seo PARK ; Kyu Sun CHOI ; Young Tack JANG ; Hong Cheul LEE ; Chun Hee LEE
Journal of the Korean Pediatric Society 1991;34(4):566-572
No abstract available.
Homocystine
;
Homocystinuria*
8.Analysis of Training Needs with Roles in College & University Foodservice Dietitians.
Myung Sook JANG ; Jin mee LEE ; Sun Young BAEK
Journal of the Korean Dietetic Association 2005;11(4):462-472
College and university foodservice dietitians have to be competent for playing a role as the future food service executive as well as the present foodservice administrator in the promising foodservice industry field. The study conducted a survey to examine training needs corresponding to educational contents for the purpose of helping them acquire a new knowledge related to self-development and duty through educational training. The results of this study suggested that training needs were differed by general characteristics of dietitians, operational characteristics of food services, and training subjects. A future study should develop systematic training strategies for dietitians.
Administrative Personnel
;
Food Services
;
Humans
;
Nutritionists*
9.Psychological Study of Leprosy Patients: III . Ambulatory Patients.
Young Pio KIM ; Kee Yul JANG ; Inn Ki CHUN ; Chang Sung YANG ; Ki Sun KIM
Korean Journal of Dermatology 1983;21(4):367-376
Many factors including social rejection, family problems, loss of educational opportunity, fear, prejudice and ignorance, compound the inherent paychologicaI stress of leprosy. In ligh.t of these problems this present study was undertaken to evaluate the psychologica.l status of 1cprosy patients. The subjects of the present study were 220 patients staying at home and 304 control people living in similar isolated areas to resettlemert villages. A self reprort symptom inventory,, SCL--90 symptom check list 90) was used and the group", were analysed and compand by many factors. The results of this study are follows. -countinue-
Humans
;
Leprosy*
;
Prejudice
;
Social Distance
10.A Clinical Study of 40 Patients with Tsutsugamushi Disease in Chungcheung Province.
Jong Seung LEE ; Jeung Hoon LEE ; Jang Kyu PARK ; Sun Young KIM ; Woo Hyun CHANG
Korean Journal of Dermatology 1989;27(3):272-282
Forty patients(9 male and 31 female) with tsutsugamushi disease were evaluated clinically. The diagnosis of tsutsugamushi disease was confirmed by indirect immunofluoresent test or isolation of causative agent. More than 77% of patients were over 40 years of age. After the incubation period(5 to 13 days, average 8 days) symptoms developed suddenly. The frequent symtoms were fever(100%), chill(100%), headache(100%), rnalaise(97%), and myalgia(95%). On physical exammination the rash, eschar, and lymphadenopathy were found in 97%, 82%, and 67% respectively. Eschar was observed in the trunk, especially axillary, abdominal and inguinal area. Serum transarninase(SGOT snd SGPT) was elevated(89 and 87%). Urinalysis revealed proteinuria in 35%(12/34) and hematuria in 19%(7/36). Chest roentgram and ECG demonstrated abnormalities in 39%(14/36) and 73%(26/36) respectively, The treatment with doxycycline was very effective in all cases.
Diagnosis
;
Doxycycline
;
Electrocardiography
;
Exanthema
;
Hematuria
;
Humans
;
Lymphatic Diseases
;
Male
;
Proteinuria
;
Scrub Typhus*
;
Thorax
;
Urinalysis