We present the cytologic features of a case of solid and papillary neoplasm of the pancreas. Cytologically, the tumor was composed of a monotonous population of polygonal cells containing eccentrically located round nuclei with one or two distinct small nucleoli and a finely stippled chromatin pattern. The tumor cells were similar to those of the islet cell tumor and showed isolated loosely aggregated and solid sheets or large cell clumps. The large cell clumps revealed a branching papillary structure containing fibrovascular central core, which is characteristic histologic feature of solid and papillary neoplasm of the pancreas. This case was confirmed by tissue examination including histochemical, immunohistochemical and electron microscopical studies. Ultrastructurally, the tumor cells contained a few membrane-bound electron dense granules.
Adenoma, Islet Cell ; Chromatin ; Pancreas ; Urinary Tract*

No abstract available.
Pneumothorax*

No abstract available.
Heart Defects, Congenital* ; Plasma*

No abstract available.

No abstract available.
Animals ; Doxorubicin* ; Rats*

The authors reviewed the patient's charts of 300 patients with ptosis(401 eyes). The patients were classified into congenital and acquired and analyzed patients according to causes and their incidences. Of all patients, 261(86%) were congenital ptosis and the remaining 39 were acquired. The most common type of convenital ptosis was simple one(85%). On the other hand, acquired ptosis composed of mechanical(35.9%) and traumatic (23.1 %) in their incidence. In regarding severity of ptosis, severe form were 72% and 45% in congenital and acquired, respectively. When compared with reports from other countries on their incidence, congenital ptosis was much higher than that of incidence.
Hand ; Humans ; Incidence

PURPOSE: We aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD). METHODS: Our study included 44 pediatric patients who were diagnosed with GD between January 1, 1993, and December 31, 2013, and were available for follow-up, achieving a normalization of thyroid functions (TFs) at the Chonbuk National University Hospital Pediatric Department. We retrospectively analyzed TFs such as tri-iodothyronine (T3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), and thyroid antibody levels at diagnosis. We also examined their family history of thyroid disease, symptoms at presentation, and normalization time for TF after treatment. We divided our clinical series of patients into the following 4 age groups: <7 years old, 7-12 years old, 13-15 years old, and 16-18 years old. RESULTS: At diagnosis, the time of normalization of T3 was significantly shorter in the higher antimicrosomal antibody (AMA) group compared with the lower AMA group (2.53 months vs. 6.18 months) (P<0.05). However, the time of normalization of T3/fT4/TSH had no significant correlations with other variables such as age, sex, a family history of thyroid diseases, thyroglobulin, thyroid-stimulating immunoglobulin, or antithyroglobulin antibody (ATA). CONCLUSION: Higher serological titers of AMA at diagnosis may have prognostic value in the response to initial MMI treatment in pediatric hyperthyroid GD patients.
Adolescent* ; Child* ; Diagnosis ; Follow-Up Studies ; Graves Disease* ; Humans ; Immunoglobulins, Thyroid-Stimulating ; Jeollabuk-do ; Methimazole* ; Retrospective Studies ; Thyroglobulin ; Thyroid Diseases ; Thyroid Gland ; Thyrotropin ; Thyroxine ; Triiodothyronine

PURPOSE: We aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD). METHODS: Our study included 44 pediatric patients who were diagnosed with GD between January 1, 1993, and December 31, 2013, and were available for follow-up, achieving a normalization of thyroid functions (TFs) at the Chonbuk National University Hospital Pediatric Department. We retrospectively analyzed TFs such as tri-iodothyronine (T3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), and thyroid antibody levels at diagnosis. We also examined their family history of thyroid disease, symptoms at presentation, and normalization time for TF after treatment. We divided our clinical series of patients into the following 4 age groups: <7 years old, 7-12 years old, 13-15 years old, and 16-18 years old. RESULTS: At diagnosis, the time of normalization of T3 was significantly shorter in the higher antimicrosomal antibody (AMA) group compared with the lower AMA group (2.53 months vs. 6.18 months) (P<0.05). However, the time of normalization of T3/fT4/TSH had no significant correlations with other variables such as age, sex, a family history of thyroid diseases, thyroglobulin, thyroid-stimulating immunoglobulin, or antithyroglobulin antibody (ATA). CONCLUSION: Higher serological titers of AMA at diagnosis may have prognostic value in the response to initial MMI treatment in pediatric hyperthyroid GD patients.
Adolescent* ; Child* ; Diagnosis ; Follow-Up Studies ; Graves Disease* ; Humans ; Immunoglobulins, Thyroid-Stimulating ; Jeollabuk-do ; Methimazole* ; Retrospective Studies ; Thyroglobulin ; Thyroid Diseases ; Thyroid Gland ; Thyrotropin ; Thyroxine ; Triiodothyronine