1.Giant Mullerian Duct Cyst: A Case Report.
Young Yo PARK ; Sun Wha LEE ; Yoo Mie HAN
Journal of the Korean Radiological Society 1995;33(1):143-146
We report a case of giant M llerian duct cyst in a 6 month-old-boy with urinary tract infection. A mass displacing the bladder and prostatic urethra anteriorly was found on the voiding cystourethrogram, and it was a oval shaped retrovesical anechoic cyst on the abdominal ultrasonogram. On MRi, it was a tear-drop shaped cyst of isosignal intensity with a projection toward the prostatic urethra and located in the midline of vesicorectal space. Grossly, the cyst had communication with prostatic urethra and both vas deferenses were drained to the cyst. Pathologically it was confirmed as a M~'llerrian duct cyst lined with squamous epithelium.
Epithelium
;
Magnetic Resonance Imaging
;
Ultrasonography
;
Urethra
;
Urinary Bladder
;
Urinary Tract Infections
;
Vas Deferens
2.A case ileal duplication with intussusception.
Gyoung Wha CHOI ; Gyoung Sun KANG ; Byung Uk PARK ; Wha Mo LEE ; Young Seak JEEN ; Tae Won LEE
Journal of the Korean Pediatric Society 1992;35(4):563-568
No abstract available.
Intussusception*
3.Diagnosis of Neuropathies for CMT1A and HNPP Using the Microsatellite Multiplex PCR System.
Byung Ok CHOI ; Sun Wha PARK ; Jiyoung YUN ; Ki Wha CHUNG
Journal of the Korean Neurological Association 2005;23(6):796-805
BACKGROUND: Tandem duplication of chromosome 17p11.2-p12 including peripheral myelin protein 22 (PMP22) gene is the most frequent cause of Charcot-Marie-Tooth 1A (CMT1A). Patients carrying one extra copy of PMP22 develop CMT1A, whereas the deletion of the 17p11.2-p12 region causes hereditary neuropathy with the liability to pressure palsies (HNPP). In the present study, we established the genotyping methods of 6 microsatellite markers (D17S921, D17S9B, D17S9A, D17S4A, D17S918 and D17S122) within the 17p11.2-p12 regions by the hexaplex PCR for the genetic diagnosis of CMT1A duplication and HNPP deletion. METHODS: We established polymorphic behavior and genotyping methods of 6 microsatellite markers (D17S921, D17S9B, D17S9A, D17S4A, D17S918 and D17S122) within the duplication region. The 6 markers were amplified by hexaplex PCR reaction and analyzed by an automatic sequencing analyzer and genotyper program. RESULTS: The genotype distributions of all markers were not significantly deviated from the Hardy-Weinberg equilibrium (P>or=0.05). When comparing the control group and CMT1A, HNPP patients group by the distribution of allele, there is no significant difference in the 5 locus except in the 1 locus (D17S921) among HNPP patients. The specificity was more than 99.9%. The sensitivity of each CMT1 and HNPP was 56.3% (40/71 pedigrees) and 72.1% (31/43 HNPP pedigrees), respectively. CONCLUSIONS: The error rate for the system may be less than 0.001. According to this study, it is possible to have rapid and exact genetic diagnosis of both CMT1A and HNPP, which may be helpful for the development of personalized therapy according to genetic defects.
Alleles
;
Charcot-Marie-Tooth Disease
;
Diagnosis*
;
Genotype
;
Humans
;
Microsatellite Repeats*
;
Multiplex Polymerase Chain Reaction*
;
Myelin Sheath
;
Paralysis
;
Polymerase Chain Reaction
;
Sensitivity and Specificity
4.Intraductal Papillary Mucinous Neoplasm of the Bile Ducts.
Sun Jin PARK ; Taek Soo KWON ; Sun Hyung JOO ; Youn Wha KIM ; Sang Mok LEE ; Sung Wha HONG
Journal of the Korean Surgical Society 2007;73(3):266-271
Intraductal papillary mucinous neoplasms of the bile ducts (IPMNs-B) are uncommon lesions that are characterized by innumerable papillary fronds that contain fine vascular cores, enriched mucin production and bile duct dilatation. IPMNs-B are histologically similar to intraductal papillary mucinous neoplasms of the pancreas and they are occasionally associated with hepatolithiasis. IPMNs-B are considered to be relatively low-grade malignancy and they merit consideration for aggressive surgery. Thus, early and precise diagnosis is important to maximize patient survival. From July 2002 to March 2006, we identified four patients with IPMNs-B at our hospital. In three patients, intrahepatic or extrahepatic bile duct stones were associated with their condition. Computed tomography and magnetic resonance cholangiography were done in all four cases and this demonstrated marked dilatation of the biliary tree. Endoscopic retrograde cholangiography was done in two cases and a large amount of mucin that was draining from the patulous orifice of the duodenal papilla was seen on endoscopy. However, two cases were initially misdiagnosed as intrahepatic cholangiocarcinoma or choledochal cyst with intrahepatic bile duct stones. All the cases underwent ipsilateral hemihepatectomy with caudate lobectomy. Histologically, one case showed to be adenoma, one case was borderline and two cases were invasive adenocarcinoma.
Adenocarcinoma
;
Adenoma
;
Bile Ducts*
;
Bile Ducts, Extrahepatic
;
Bile Ducts, Intrahepatic
;
Bile*
;
Biliary Tract
;
Cholangiocarcinoma
;
Cholangiography
;
Choledochal Cyst
;
Diagnosis
;
Dilatation
;
Endoscopy
;
Humans
;
Mucins*
;
Pancreas
5.Modified Huches Procedure.
Young Boon PARK ; Wha Sun JUNG
Journal of the Korean Ophthalmological Society 1988;29(5):937-942
The authors performed reconstructive surgery for three cases of extensive upper and lower lid defects using modified Hughes procedure during the past one year. Two cases were upper lid reconstruction for the recurrent sebaceous carcinoma and the upper lid coloboma due to thermal bum. The other one was the adenoid cystic carcinoma of the lower lid. The first stage of this procedure was performed by tarsoconjunctival flap. The second procedure was performed after 6 weeks. This lid sharing technique was excellent for both cosmesis and lid function. All of the three patients have been very happy without any complications such as malposition of the lid margin, lid retraction or blepharoptosis.
Blepharoptosis
;
Carcinoma, Adenoid Cystic
;
Coloboma
;
Humans
6.Functional Obstruction of The Lacrimal Draings System.
Journal of the Korean Ophthalmological Society 1995;36(9):1435-1438
Functional lacrimal obstruction is a rare physiologic dysfunction of the lacrimal drainage system without any mechanical obstruction. Twelve eyes of 9 patients were diagnosed by syringing, dacryacystography, and lacrimal scintigraphy. Normal drainge pattern was noticed in syringing and in the initial film of dacryocystography. However slow or non-functioning drainge was disclosed in the delay film of dacryocystography and lacrimal scintigraphy. The causes of functional problem were facial nerve palsy, trauma and idiopathic. Conjunctivodacryocystorhinostomy was performed in all 12 eyes with satisfactory results.
Drainage
;
Facial Nerve
;
Humans
;
Paralysis
;
Radionuclide Imaging
7.Fibrochondrodysplasia.
Kyung Nam RYU ; Yong Koo PARK ; Yong Girl RHEE ; Sun Wha LEE ; Jae Hoon LIM
Journal of the Korean Radiological Society 1991;27(2):286-288
No abstract available.
8.Intraorbital Dermis-Fat Graft.
Journal of the Korean Ophthalmological Society 1988;29(4):621-637
We studied ten patients who received autogenous dermis-fat implantation in anophthalmic sockets during the last one year. Eight cases were performed after primary enucleation and two cases were used as a secondary implant for socket problems. This technique preserves good fornices and supplies movable implants with little chance of fat atrophy or extrusion.
Atrophy
;
Equipment and Supplies
;
Humans
;
Transplants*
9.A Case of Symmetrical Peripheral Gangrene in Disseminated Intravascular Coagulation.
Mi Jeong KIM ; Seung Hee PARK ; Sun Wha KIM ; Don Hee AHN
Journal of the Korean Pediatric Society 1994;37(11):1620-1623
The symmetrical peripheral gangrene syndrome consists of sudden onset of symmetrical gangrene of the fingers, toes and more raely, the nose, upper lip, ear lobes, or genitalia. There is no evidence of occulusion of large vessels or vasculitis. We experienced a case of symmetrical peripheral gangrene developed in fingers and toes with disseminated intravascular coagulation in 20 day-old permature infant with sepsis by Enterobacter aerogenes. Thereafter, we presented a case with a brief review of the related literatures.
Disseminated Intravascular Coagulation*
;
Ear
;
Enterobacter aerogenes
;
Fingers
;
Gangrene*
;
Genitalia
;
Humans
;
Infant
;
Lip
;
Nose
;
Sepsis
;
Toes
;
Vasculitis
10.A Survey of the Outcome of Childhood Asthma.
Hyung Ja PARK ; Myung Ik LEE ; Sun Wha KIM ; Don Hee AHN ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1987;30(1):55-63
No abstract available.
Asthma*