1.Analysis to the Therapeutic Effect of Acupuncture for Restoring Consciousness and Inducing Resuscitation in Promoting Revival of Coma for the Patient of Diffuse Axonal Injury
Xuedong SUN ; Shushen LIU ; Zhuangzhi LI
International Journal of Traditional Chinese Medicine 2009;31(4):341-342
Objective To investigate the therapeutic effect of acupuncture for restoring consciousness and inducing resuscitation in promoting revival of coma for the patient of diffuse axonal injury(DAI). Methods 60 cases of DAI (GCS≤ 8) were randomly recurited into a control group and a treatment group. The control group was treated by routine treatment, while the treatment group was treated with acupuncture on the basis of routine treatment .The improving rate of consciousness at the two months of treatment was compared between the two group, and the prognosis was evaluated according to GOS scores. Results The revival rate in the treatment group was 86.7%, higher than that of 60.0% in the control group (P<0.05). The revival time in the treatment group was shorter than the control group (X2=5.45、 t= 8.051, P<0.05 ) .Conclusion The integrated therapy of acupuncture for restoring consciousness and inducing resuscitation and western medicine can promote the effect of coma revival and improve life condition for the patient of DAI.
2.Predictive value of early gastric cancer model for disease progression in high-risk pop-ulations
Sun SHUSHEN ; Song RUI ; Li XUE ; Lv HONGMIN
Chinese Journal of Clinical Oncology 2024;51(5):231-235
Objective:To assess the value of a model based on helicobacter pylori(Hp)status and peripheral blood levels of pepsinogen Ⅰ(PGⅠ),PGⅡ,and gastrin-17(G-17)for predicting disease progression in high-risk populations for gastric cancer.Methods:Retrospective se-lection of clinical data from 126 high-risk individuals for gastric cancer who underwent PGⅠ,PGⅡ,G-17,and C14 urea breath tests and gastro-scopy tissue biopsy at Tianjin University Jinnan Hospital from January 2023 to January 2024,Based on pathological biopsy results using gast-ric cancer tissues obtained by gastroscopy,the high-risk population for gastric cancer was assigned into normal control,precancerous lesion,and early gastric cancer groups.The diagnostic efficacies of PGⅠ,PGⅡ,G-17,C14 urea breath,and other indicators in each patient group were determined,and a predictive model was constructed.Results:The HP-positivity rate(82.35%)and PGⅡ level(22.73 ng/mL)in the early gastric cancer group were higher than those in the precancerous lesion and control groups.The PGI level(51.36 ng/mL)was lower in early gastric cancer than in precancerous lesions and control tissues.The G-17 level(5.17 pmol/L)was lower in the precancerous lesion group than in the control and early gastric cancer groups(P<0.05).Combined use of PGⅠ、PGⅡ、G-17and Hp,the area under curve(AUC)can reach 0.899,a sensitivity of 94.12%,and a specificity of 95.65%,making these factors ideal diagnostic tools for gastric cancer.According to the prediction model,the threshold for precancerous lesions was 10 points,and the critical value for early cancer was 19 points.Conclu-sions:Implementation of the C14 urea breath test combined with PGⅠ,PGⅡ,and G-17 detection in high-risk populations for gastric cancer can help monitor disease progression in high-risk populations for gastric cancer.