PURPOSE: The purpose of this study was to investigate the influencing factors on externalized and internalized problem behaviors among high school students. METHODS: The subjects for this study were 707 students in two high schools in K province. The data were collected during the period from October to November, 2014 by use of questionnaires. The instruments used were the Korean Youth Self-report, Daily Hassles Questionnaire, State-Trait Anger Expression Inventory, and Ego Resiliency Scale. The data were analyzed using SPSS. RESULTS: Significant predictors to explain externalized problem behaviors comprised anger-out, anger-in, anger-control, relation with parents, daily stress, and religion. It was found that these factors explained 46% of externalized problem behavior. Ego resiliency, anger-in, daily stress, gender, relation with parent, and anger-out were significant predictors to explain internalized problem behaviors. It was found that these factors explained 45% of internalized problem behaviors. CONCLUSION: This study suggests that the influencing factors on problem behaviors differ from externalized and internalized problem behaviors. So these findings will provide the basic data to develop a program that is differentiated by problem behavior type.
Adolescent* ; Anger ; Ego ; Humans ; Parents ; Problem Behavior* ; Stress, Psychological

PURPOSE: This study was conducted to examine the mediating effect of meaning in life on the relationship between social connectedness and depression among middle-aged women.METHODS: A descriptive correlational design was employed. One hundred and forty-two middle-aged women who visited welfare centers or churches in Seoul and Gyeonggi Province participated in the study. The data were collected from May to June, 2019 and analyzed using descriptive statistics, Pearson's correlation coefficients, and multiple linear regression analyses based on Baron and Kenny criteria.RESULTS: Social connectedness was significantly positively correlated with meaning in life (r=.52, p < .001) and negatively with depression (r=−.53, p < .001). Meaning in life was also significantly negatively correlated with depression (r=−.50, p < .001). Furthermore, meaning in life had a significant mediating effect on the relationship between social connectedness and depression (β=−.31, p < .001).CONCLUSION: Our study findings suggest that meaning in life plays an important role in maintaining mental health and well-being for middle-aged women. Therefore, it is necessary to develop a nursing intervention program that can enhance the meaning in life to promote mental health and well-being.
Depression ; Female ; Gyeonggi-do ; Humans ; Linear Models ; Mental Health ; Negotiating ; Nursing ; Seoul

No abstract available.
Empyema, Subdural* ; Haemophilus influenzae* ; Haemophilus* ; Meningitis*

Purpose: To evaluate the short-term efficacy and safety of latanoprostene bunod 0.024% in patients with primary open-angle glaucoma. Methods: A retrospective study was conducted from September 2022 to September 2023, involving 29 eyes from patients diagnosed with primary open-angle glaucoma. The study analyzed the intraocular pressure (IOP)-lowering effects of latanoprostene bunod 0.024% at 1 and 3 months after administration. Additionally, adverse events reported by patients at each visit were documented. Results: The mean age of patients at the start of treatment was 64.46 years. The baseline IOP was 17.46 ± 4.03 mmHg, which significantly decreased to 15.07 ± 4.23 mmHg (p = 0.002) at 1 month (29 eyes) and 14.93 ± 3.86 mmHg (p = 0.002) at 3 months (28 eyes) after latanoprostene bunod administration. After 1 month, 9 patients reported adverse events, including conjunctival hyperemia (1 eye, 3.5%), itching (2 eyes, 6.9%), foreign body sensation (2 eyes, 6.9%), stinging (2 eyes, 6.9%), ocular pain (2 eyes, 6.9%), and deepening of the upper eyelid sulcus (1 eye, 3.5%). The patient who experienced deepening of the upper eyelid sulcus discontinued treatment. After 3 months, 2 eyes with itching discontinued treatment due to conjunctival allergy. Conclusions Latanoprostene bunod 0.024% demonstrated short-term efficacy in reducing IOP and a manageable safety profile in patients with primary open-angle glaucoma.

Purpose: To evaluate the short-term efficacy and safety of latanoprostene bunod 0.024% in patients with primary open-angle glaucoma. Methods: A retrospective study was conducted from September 2022 to September 2023, involving 29 eyes from patients diagnosed with primary open-angle glaucoma. The study analyzed the intraocular pressure (IOP)-lowering effects of latanoprostene bunod 0.024% at 1 and 3 months after administration. Additionally, adverse events reported by patients at each visit were documented. Results: The mean age of patients at the start of treatment was 64.46 years. The baseline IOP was 17.46 ± 4.03 mmHg, which significantly decreased to 15.07 ± 4.23 mmHg (p = 0.002) at 1 month (29 eyes) and 14.93 ± 3.86 mmHg (p = 0.002) at 3 months (28 eyes) after latanoprostene bunod administration. After 1 month, 9 patients reported adverse events, including conjunctival hyperemia (1 eye, 3.5%), itching (2 eyes, 6.9%), foreign body sensation (2 eyes, 6.9%), stinging (2 eyes, 6.9%), ocular pain (2 eyes, 6.9%), and deepening of the upper eyelid sulcus (1 eye, 3.5%). The patient who experienced deepening of the upper eyelid sulcus discontinued treatment. After 3 months, 2 eyes with itching discontinued treatment due to conjunctival allergy. Conclusions Latanoprostene bunod 0.024% demonstrated short-term efficacy in reducing IOP and a manageable safety profile in patients with primary open-angle glaucoma.

Purpose: To evaluate the short-term efficacy and safety of latanoprostene bunod 0.024% in patients with primary open-angle glaucoma. Methods: A retrospective study was conducted from September 2022 to September 2023, involving 29 eyes from patients diagnosed with primary open-angle glaucoma. The study analyzed the intraocular pressure (IOP)-lowering effects of latanoprostene bunod 0.024% at 1 and 3 months after administration. Additionally, adverse events reported by patients at each visit were documented. Results: The mean age of patients at the start of treatment was 64.46 years. The baseline IOP was 17.46 ± 4.03 mmHg, which significantly decreased to 15.07 ± 4.23 mmHg (p = 0.002) at 1 month (29 eyes) and 14.93 ± 3.86 mmHg (p = 0.002) at 3 months (28 eyes) after latanoprostene bunod administration. After 1 month, 9 patients reported adverse events, including conjunctival hyperemia (1 eye, 3.5%), itching (2 eyes, 6.9%), foreign body sensation (2 eyes, 6.9%), stinging (2 eyes, 6.9%), ocular pain (2 eyes, 6.9%), and deepening of the upper eyelid sulcus (1 eye, 3.5%). The patient who experienced deepening of the upper eyelid sulcus discontinued treatment. After 3 months, 2 eyes with itching discontinued treatment due to conjunctival allergy. Conclusions Latanoprostene bunod 0.024% demonstrated short-term efficacy in reducing IOP and a manageable safety profile in patients with primary open-angle glaucoma.

Purpose: To assess the effectiveness of an automated screening program that diagnoses horizontal strabismus using machine learning based on ocular deviation data captured by the wearable eyetracker, Tobii pro glasses 2 (TPG2). Methods: The TPG2 which locates the pupil center to measure ocular movement was used. In normal adults wearing TPG2, horizontal ocular deviation was induced by covering the left eye and applying prisms of varying strengths (2, 3, 4, 5, 6, 8, 10, 12, 15, 20, 25, 30, 35, and 40 PD base-in and out) to the right eye. TPG2 automatically recorded ocular deviation before and after prism induction generating 28 types of ocular deviation sets. From each set, 20 X-axis values before and after ocular deviation were randomly extracted using an oversampling technique creating a total of 61,600 ocular deviation sets. For training, 56,000 sets were used and 5,600 were evaluated for sensitivity, specificity, and area under the curve (AUC). Results: Eleven normal adults (5 males) participated with a mean age of 34.8 ± 7.37 years. Based on an 8 PD threshold, deviations of 8 PD or less demonstrated a sensitivity of 1.0, a specificity of 0.95, and an AUC of 0.97. When categorized into three groups based on 8 PD and 20 PD thresholds, the results were: sensitivity of 0.90 and specificity of 0.95 for ≤ 8 PD; sensitivity of 0.60 and specificity of 1.00 for 8-20 PD; sensitivity of 1.00 and specificity of 0.88 for > 20 PD. Conclusions The machine learning program developed using induced ocular deviations measured with prisms and TPG2 shows promise for use in future strabismus screening tests.

PURPOSE: The purpose of this study was to examine the effects of the mental health promotion program based on Positive Psychology for adolescents with problem behavior. METHODS: The study used a nonequivalent control group pretest-posttest design. Eligible participants were first grade students in two high schools in K Province. The inclusion criteria for the study were those with scores in the upper 15% on the Korean Youth Self-Report. A total of 74 participants were assigned to an 8-session program (n=38) or to a control (n=36) group. The outcome variables were psychological well-being, depression, and self-esteem. RESULTS: There were no statistically significant differences in demographic variables or outcome variables, except self-esteem, between the two groups at the baseline. The experimental group had higher mean scores on psychological well-being and self-esteem and a lower mean score on depression. There were significant differences in psychological well-being (t=3.45, p=.001), self-esteem (F=5.45, p=.022), and depression (t=-2.80, p=.007) between the two groups. CONCLUSION: The mental health promotion program based on Positive Psychology was effective in decreasing depression as well as improving psychological well-being and self-esteem for adolescents with problem behavior. This study contributes to suggesting a framework for promoting mental health for high school students with problem behavior.
Adaptation, Psychological ; Adolescent* ; Depression ; Humans ; Mental Health* ; Problem Behavior* ; Program Evaluation ; Psychology* ; Self Concept

PURPOSE: The purpose of this study was to identified the male nurses' encounter in adapting themselves in the hospital settings dominated by the female nurses in number. METHOD: Data were collected through the in-depth interview of 16 male nurses and analysed through the grounded theory methodology. RESULT: The behaviors of male nurses for job-adaptation can be summarized as a series of struggles to consolidate their own ground. They have made tremendous efforts to hold their own ground in the nursing profession composed of a large numbers of female nurses, while they have experienced many difficulties and problems as minorities. They have struggled to adapt themselves professionally through efforts such as; challenging the social and professional barriers, identifying the job identity, empowering themselves through self-development and dedication, expanding their influence among colleagues. In spite of these efforts, they had the perception that nursing is not a lifelong occupation for them. Thus, they had tendency to find outlets of change to occupations. CONCLUSION: A specific strategy is needed to provide an environment that is helpful for males in integrating into and adapting to the nursing profession.

This study evaluated the pharmacokinetic profile and therapeutic efficacy of piroxicam (PX), a long acting non-steroidal anti-inflammatory drug for the treatment of arthritis, following intra-articular (IA) injection in comparison to the pharmacokinetic profile and therapeutic efficacy of PX after intramuscular (IM) injection. In the pharmacokinetic study in rats, systemic exposure and pharmacokinetic parameters of PX after a single IA dose were compared with systemic exposure and pharmacokinetic parameters of PX after administration of the same dose IM (0.6 mg/kg). The anti-inflammatory and analgesic effects of IA PX were evaluated simultaneously in a monoiodoacetate-induced osteoarthritis rat model. The plasma PX concentration rapidly rose following IA injection, and it was comparable to the plasma PX concentration following IM injection, suggesting the rapid efflux of the drug molecule from the joint cavity. However, in the efficacy study, the IA PX administration significantly reduced the knee swelling by reducing the level of prostaglandin E2 in the joint, compared to that following administration of IA vehicle and after administration of the IM PX dose. In addition, we found that the anti-inflammatory and anti-nociceptive efficacies of IA PX were synergistically increased upon co-treatment with hyaluronic acid (HA), a potent agent for the treatment of osteoarthritis, at the weight ratio of 1:1 or 1:2, and these effects were more pronounced than those following administration of HA or PX alone. In conclusion, this study demonstrated the efficacy of the IA use of PX alone and/or in combination with HA in osteoarthritis.
Animals ; Arthritis ; Dinoprostone ; Hyaluronic Acid ; Injections, Intra-Articular ; Joints ; Knee ; Models, Animal ; Osteoarthritis ; Pharmacokinetics* ; Piroxicam* ; Plasma ; Rats*