1.Diagnostic Value of Computed Tomography in Acetabular Fracture.
Sun Yong KIM ; Bok Hwan PARK ; Joo Chul IHN
Yeungnam University Journal of Medicine 1988;5(1):43-48
We retrospectively analyzed 22 patients pelvic CT, in whom the acetabular fracture were suspected in plain film. And compared and analyzed the computed tomogram findings and plain radiographic findings. The results were as follows. CT enables better evaluation of shape, extent, and degree of separation of fragment. CT was helpful in detecting the combined fracture and soft tissue injuries. CT showed intraarticular loose bodies, which were invisible on plain film. In patients with pelvic trauma, no necessary changing position during CT examination. CT was useful demonstrates the remnant of intraarticular osseous fragment and adequacy of reduction after surgery.
Acetabulum*
;
Humans
;
Retrospective Studies
;
Soft Tissue Injuries
2.The Clinical Study of Transient Synovitis of the Hip Joint in Children
Sun Ho LEE ; Hyung Jip CHOI ; Bong Joo PARK
The Journal of the Korean Orthopaedic Association 1984;19(5):819-824
Transient synovitis of the hip joint in children was first described by Lovett and More in 1892and is the commonest cause of painful hip in children. It is characterized by pain and limp of acute onset, generally shart-lived, unassociated with structural changes in the femoral capital epiphysis demonstrable roentgenographically.. The pathology is of interest, not because it is a disabling condition, but because of the difficulties in differentiating it from more serious disease of the hip such as Legg-Calve-Perthes disease, tuberculosis, osteomyelitis and etc. The 76 cases so diagnosed at the Han-II hospital from 1974 to 1983 were reviewed and reported as follows; 1. There was probably associated with predisposing factors such as infection, and trauma. 2. The diagnostic criteria were clinical symptoms, laboratory and radiological findings. 3. The treatment was bed rest, skin traction on the affected leg, non-weight bearing, antibiotics, sedatives and in a few cases, INH was administrated for the prevention of the tuberculosis. 4. Four hips among them revealed later as Legg-Calve-Perthes disease and tuberculous arthritis of the hip joint.
Anti-Bacterial Agents
;
Arthritis
;
Bed Rest
;
Causality
;
Child
;
Clinical Study
;
Epiphyses
;
Hip Joint
;
Hip
;
Humans
;
Hypnotics and Sedatives
;
Leg
;
Legg-Calve-Perthes Disease
;
Osteomyelitis
;
Pathology
;
Skin
;
Synovitis
;
Traction
;
Tuberculosis
3.Benefits of a Cholecystostomy and Review of 1000 Consecutive Laparoscopic Cholecystectomies.
Lee Ho JOO ; Byung Sun CHO ; Joo Seung PARK
Journal of the Korean Surgical Society 1998;54(1):101-108
The laparoscopic cholecystectomy, performed for the first time in France in 1987, has been accepted as in many countries the method of choice when performing a cholecystectomy. The trend toward minimally invasive surgery has prompted general surgeons to try it instead of open cholecystectomy. We performed 1000 laparoscopic cholecystectomies at the Department of General Surgery of Eulji Medical College Hospital from January 1992 to April 1997. The outcome data have been analyzed retrospectively. Moreover, we have compared the case histories of 13 patients who received cholecystostomy with those of 43 patient who did not. We also present preliminary results for an interval laparoscopic cholecystectomy which was a preceded by percutaneous cholecystostomy. The results are as follows: 1) The mean age was 54.3 years ranging from 17 to 86; there were 402 males and 598 females. 2) Of the 1000 patients, 123 patients (12.3%) had a history of abdominal surgery. 3) More than half of the patients(560 patients, 56.0%) underwent operations within 6 months of the onset of symptoms. 4) A preoperative endoscopic retrograde cholecystoscopy was performed on 220 patients (22.0%), and of these, 93 patients received endoscopic sphincterotomies because of bile duct stones. 5) The majority of patients(744 patients, 74.4%) had laparoscopic cholecystectomies which lasted 40 minutes or less. 6) More than half (54%) of the removed gallbladders showed grade II inflammation. 7) Drains were used in 142 patients (14.2%). 8) Postoperative complications were encountered in 48 patients (4.8%). 9) Postoperative oral intake was resumed within 24 hours in most patients. 10) Most patients(854 patients, 85.4%) were discharged within 3 days of the operation. 11) The pathologic diagnosis was chronic nonspecific inflammation in most cases (823 cases, 82.3%). 12) The most common microorganism in the bile was E. coli. 13) Patients who received a cholecystostomy had many benefits: a shorter operation time, a low rate of open cholecystectomy, early oral intake. 14) For the 1160 patients who underwent a cholecystectomy during the same period, the rate of open cholecystectomy was 13.8%.
Bile
;
Bile Ducts
;
Cholecystectomy
;
Cholecystectomy, Laparoscopic*
;
Cholecystostomy*
;
Diagnosis
;
Female
;
France
;
Gallbladder
;
Humans
;
Inflammation
;
Male
;
Postoperative Complications
;
Retrospective Studies
;
Sphincterotomy, Endoscopic
;
Surgical Procedures, Minimally Invasive
4.Factors Influencing Physical Activity among Community-dwelling Older Adults with Type 2 Diabetes: A Path Analysis.
Sun Joo JANG ; Hyunju PARK ; Hyunjung KIM ; Sun Ju CHANG
Journal of Korean Academy of Nursing 2015;45(3):329-336
PURPOSE: The purpose of the study was to identify factors influencing physical activity among community-dwelling older adults with type 2 diabetes. The study design was based on the Theory of Triadic Influence. METHODS: A total of 242 older adults with type 2 diabetes participated in this study. Six variables related to physical activity in older adults, including self-efficacy, social normative belief, attitudes, intention, experience, and level of physical activity, were measured using reliable instruments. Data were analyzed using descriptive statistics, Pearson's correlation analyses, and a path analysis. RESULTS: The mean physical activity score was 104.2, range from zero to 381.21. The path analysis showed that self-efficacy had the greatest total effect on physical activity. Also, experience had direct and total effects on physical activity as well as mediated the paths of social normative beliefs to attitudes and intention to physical activity. These factors accounted for 10% of the total variance, and the fit indices of the model satisfied the criteria of fitness. CONCLUSION: The findings of the study reveal the important role of self-efficacy and past experience in physical activity in older adults with type 2 diabetes.
Aged
;
Aged, 80 and over
;
Attitude
;
Diabetes Mellitus, Type 2/*physiopathology/psychology
;
Female
;
Humans
;
Male
;
Motor Activity/*physiology
;
Personal Satisfaction
;
Residence Characteristics
;
Self Efficacy
;
Surveys and Questionnaires
5.A case of multiple endobronchial hamartomas.
Sung Kyu PARK ; Kyoung Joo RHEE ; Mee Ja PARK ; Sun Young KIM
Tuberculosis and Respiratory Diseases 1992;39(1):83-88
No abstract available.
Hamartoma*
6.Regulation of TNF - alpha Gene Expression in Human Fetal Astrocytes.
Hye Myung RYU ; Joo Young PARK ; Sun Ju CHOI ; Hyun Sook PARK ; Choon Myung KOH
Journal of Bacteriology and Virology 2001;31(3):291-297
Tumor necrosis factor-n (TNF - alpha) involved in the pathogenesis of multiple sclerosis and contribute to the degeneration of oligodendrocytes as well as neurons. TNF - alpha is produced by miocroglia and astrocytes, which also produce hormones and cytokines that influence its biological activity. Astrocytes, the major glial cells in the CNS, are capable of producing TNF - alpha at both the mRNA and protein levels in response to interleukine-1 (IL-1) or TNF - alpha. Two immunosuppressive cytokines, transforming growth factor - beta (TGF - beta) and IL-10, have been shown to influence glial cell function. TGF - beta can modulate the activity of glial cells by inhibiting interferon-gamma (IFN - gamma) induced expression of class II major histocompatibility complex (MHC) molecules on astrocytes and microglia. To explore the role of astrocytes in the production of TNF - alpha, astrocytes were pretreated with IL-10 or TGF - beta and then stimulated with IL-1p to determine their effects on TNF - alpha production. The secretion of TNF - alpha by human fetal astrocytes was markedly inhibited by TGF - beta at a low concentration. In contrast IL-10 had no effect on TNF - alpha mRNA level. These results show that TGF - beta may regulate the expression of TNF - alpha in activated human fetal astrocytes.
Astrocytes*
;
Cytokines
;
Gene Expression*
;
Humans*
;
Interferon-gamma
;
Interleukin-10
;
Major Histocompatibility Complex
;
Microglia
;
Multiple Sclerosis
;
Necrosis
;
Neuroglia
;
Neurons
;
Oligodendroglia
;
RNA, Messenger
;
Transforming Growth Factors
7.Characterization and Distribution of Dendritic Cells and Tissue Macrophages in the Rat Ovary.
Sik YOON ; Yeon Joo CHOI ; Su Young KO ; Sun Mi PARK ; Bong Soo PARK
Korean Journal of Anatomy 1997;30(1):1-14
This study was undertaken to investigate the characterization and distribution patterns of MHC class II positive dendritic cells[DCs] and ED2 positive tissue macrophages throughout the estrous cycle and during pregnancy in the rat ovary. The immunohistochemical characterization of the cells was carried out using the monoclonal antibodies OX6 and ED2 in cryostat-cut sections. DCs were distributed in the theca cell layer of the growing and mature follicles,stroma and corpus luteum. Tissue macrophages were distributed in the theca externa of the growing and mature follicles, stroma and corpus luteum but they were smaller in number than DCs. None of DC and tissue macrophage was found in the ovum, granulosa layer and follicular cavity of the ovarian follicle. However, DCs and tissue macrophages were present in the granulosa layer and follicular cavity in the atretic follicles. Degenerating corpus luteum contained a vast number of OX6 positive cells. On the contrary, fewer tissue macrophages were founcl in the degenerating corpus luteum. More macrophages tended to be observed in the former follicular cavity and theca lutein cell layer than in the granulosa lutein cell layer of the corpus luteum. In stroma,DCs and tissue macrophages were more frequently found around the blood vessels than in the other region, however, DCs were relatively greater in number than tissue macrophages. There was no estrous cycle and pregnancy dependent variation in the numbers and distribution patterns of DCs and tissue macrophages. In conclusion, the rat ovary contains rich networks of MHC class II positive dendritic cells and ED2 positive tissue macrophages. These findings suggest the existence of a well-developed system of immunological surveillance in the rat ovary. The results of this study have potentially important implications for the understanding not only of the ovarian immune system and the pathogenesis of various ovarian diseases but also of various physiologic functions of the ovary.
Animals
;
Antibodies, Monoclonal
;
Blood Vessels
;
Corpus Luteum
;
Dendritic Cells*
;
Estrous Cycle
;
Female
;
Immune System
;
Immunologic Surveillance
;
Luteal Cells
;
Macrophages*
;
Ovarian Diseases
;
Ovarian Follicle
;
Ovary*
;
Ovum
;
Pregnancy
;
Rats*
;
Theca Cells
8.Detection of ras gene mutations in human cancer by PCR-SSCP.
Chul Min KIM ; Joo In PARK ; Chi Duk KANG ; Sun Hee KIM ; Young Hong PARK ; Soo Ja JUNG ; Byung Sun JUNG
Journal of the Korean Cancer Association 1993;25(3):429-444
No abstract available.
Genes, ras*
;
Humans*
9.A Case of Tetrasomy 9P.
Jeong Hae JOO ; Hong Sun JOO ; Son Sang SEO ; Sook Ja PARK
Journal of the Korean Society of Neonatology 1997;4(1):72-76
Supernumerary isochromosome resulting in autosomal tetrasomy are rare and have been described only for 12P, 18P, and 9P. Tetrasomy 9P, initially described by Ghymer et al, is a rare chromosomal aberration that has been described in 20 patients. Affected subjects show both cytogenetic and ohenotypic variability. Some patients have the abnormal cell line in all cells, but many display tissue limited mosaicism. The phenotype varies in severity from prenatal death to mild developmental delay and minor anomalies. We reported a infant with mild manifestations of tetrasomy 9p with brief review of related literatures.
Cell Line
;
Chromosome Aberrations
;
Cytogenetics
;
Humans
;
Infant
;
Isochromosomes
;
Mosaicism
;
Phenotype
;
Tetrasomy*
10.Diagnostic Value of QT and JT Dispersion in Exercise ECG.
Hui Nam PARK ; Young Hoon KIM ; Sang Weon PARK ; Do Sun LIM ; Chang Gyu PARK ; Hong Seog SEO ; Wan Joo SHIM ; Dong Joo OH ; Young Moo RO
Korean Circulation Journal 1995;25(3):560-567
BACKGROUND: QT dispersion(QTD : QTmax-QTmin) or JT dispersion(JTD:JTmax-JT-min)in 12 leads ECG has been known to reflect regional variations in ventricular repolarization and has been reported to bel one of the marker of regional myocardial ischemia. To evaluate the significance of QTD or JTD of exercise ECG in diagnosis of coronary artery disease, we studied 106 patients(mean age, 56.9 years old, male 63) who were referred for the evaluation of chest pain on exertion. METHOD: Treadmill exercise stress test with modified Bruce protocol and coronary angiography were performed in 106 patients with chest pain on exertion. ST-segment depression by >1.0 mm 0.08 second after J-point during or after exercise in exercise test and >50% stanosis of epicardial artery in coronary angiogram were defined as positive. Of 106 patients, 41 had positive exercise ECG and positive coronary angiogram(true positive, TP), 20 had positive exercise ECG and negative coronary angiogram(false positive, FT), 20 had negative exercise ECG and positive coronary angiogram(faalse negative, FN), and 23 had negative exercise ECG and negative coronary angiogram(true negative, Tn). QT and JT interval in 12 leads were measured at baseline and peakexercise and were corrected for heart rate using Bazett's formula. QTD and JTD were measured by calculation the difference between the maximum QT and mininum QT and that between maximum JT and minumum JT. RESULTS: QTD at baseline for TP(72.8ms)was prolonged compared to Tn(52.2ms,P<0.01), but was not different from that for FT(70.2 ms). At peak exercise, QTD for TP(81.3 msec) was significantly prolonged(p<0.01), while QTD for FP(71.2 msec) was not different from that for TN(56.8 msec). JTD at baseline(78.4 msec) and at peak exercise(88.2 msec) for TP were significantly prolonged compared to those for TN(55.2msec and 55.1msec p<0.01,p<0.01, respectively), but those for FP were not porlonged(77.0msec and 79.0msec, respectively). QTD and JTD at peak exercise were more markedly prolonged in patients with sever stenosis of coronary artery(p=0.053 and p<0.05, repectively) and multivessels diseases(p<0.01, 0<0.05) than those with less severe disease and single vessel disease. Patients with left anterior descending artery lesion had greater QTD and JTD at peak exercise than those with other vessels lesion(p<0.01). In addition to standard criteria with ST segment displacement in exercise EGC, inclusion of exercise induced QTD of more than 60msec increased the sensitivity of exercise ECG from 66.7% to 83.3%, and JTD of more than 70msec increased the specificity from 52% to 76.0%. CONCLUSION: Measurement of QT dispersion and JT dispersion of exercise ECG may be useful method to identify the severity of coronary artery disease and to improve diagnostic accuracy of exercise ECG in coronary artery disease.
Arteries
;
Chest Pain
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease
;
Depression
;
Diagnosis
;
Electrocardiography*
;
Exercise Test
;
Heart Rate
;
Humans
;
Male
;
Myocardial Ischemia
;
Sensitivity and Specificity