1.Digital Vascular Cold Reactions in Korean Farmers during Finger Immersion in Cold Water.
Journal of the Japanese Association of Rural Medicine 1997;46(4):665-678
We investigated the cold reaction of fingers in cold water as a criterion of peripheral resistance to frostbite in order to obtain elementary data to improve farmers' health. Experiments were carried out on 81 farmers and 64 urbanites at 20±2°C, 55±5% RH with sitting position on the floor. The finger skin temperatures of the subjects were measured while the left middle finger of each subject was immersed in cold water or 0°C for 30 minutes and recorded once every one minute with the thermistor. We also compiled statistics on the following items: mean finger skin temperature (MST), finger skin temperature at initial rising after immersion (TFR), time for the appearance of initial rising after immersion (TTR), cold resistance index (RI), etc. The results were as follows RI was higher in farmers than in urbanites, but there was no significant difference between the two groups. In men, RI was lower in farmers than in urbanites, but there was no significant difference between the two groups. By contrast, in women, TFR and RI were significantly higher in farmers than in urbanites. MST was significantly higer in women than in men, but RI was no statistically significant difference. By age, the men in their 30's showed significantly the highest MST and the shortest TFR. RI was significantly higher in the men in their 30's than others. In women, however, the difference in RI was of no statistical significance. By region, MST was the highest in Seoul dwellers. RI was the highest in Okku dwellers, but there was no statistically significant difference among regions.
These results indicated that farmers tended to be higher than urbanites in cold resistance index.
2.Correlations among Physiques, Physical Fitness and Digital Vascular Hunting Reaction during Finger Immersion in Cold Water in Farmers.
Journal of the Japanese Association of Rural Medicine 1999;48(1):1-12
To collect the basic data for the health management of Korean farmers, we investigated physique factors, physical fitness, and cold resistance (by digital vascular hunting reaction during finger immersion in cold water), and examined their correlations in 74 subjects. In men, the stronger the digital vascular hunting reaction was the higher the physical fitness levels. For women, however, the motility of those who showed stronger digital vascular hunting reactions appeared worse. The correlation between physique and hunting reaction appeared weak in men but in women the hunting reaction of obese subjects was stronger than that of slender subjects. Agewise, men in their 30s, 40s and 50s who were short and slim appeared to have better cold-resistance. The men in their 60s who were broad-hipped had better cold-resistance, and the relation between physical fitness and hunting reaction appeared to be negative. In contrast, the women in their 30s whose subcutaneous fat was thinner showed positive hunting reaction, but in their 40s and 50s the correlation among physique, physical fitness, and hunting reaction appeared rather weak. The body fat content in the women aged 60 to 69 was high compared to that in other age groups. Among them, those who had less fat and better physical fitness showed more favorable hunting reactions.
3.Pelvic Drainage Following Radical Hysterectomy with Pelvic Lymphadenectomy for Cervical Cancer: Is it Necessary? .
Jin JEONG ; Kung Hun KIM ; Ho Sun CHOI
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(3):251-257
OBJECTIVES: This study was to determine whether drainage after radical hysterectomy and bilateral pelvic lymphadenectomy can reduce the risk of postoperative morbidity as compared with no drainage. METHODS: 165 patients with stage Ia2 to Ilb underwent radical hysterectomy and bilateral pelvic lymphadenectomy between January 1995 and May 1997, and those medical records were analyzed, Closed suction drains were placed in group I (n 102), not in group II (n 67). All surgeries were perforrned by the same surgeon in a uniform method. RESULTS: The characteristics of two groups were similar for mean age, preoperative weight, total protein, serum albumin, tumor cell histology, invasion depth, and tumor stage. There was no difference in mean operation time in two groups. But mean estimated blood loss was more in group I than group lI(p<0.05), Postoperative ileus and postoperative stay was similar in both groups. The incidence of pelvic lymphocyst and febrile morbidity in two groups were comparable with 17% in group I and 27% in poup II, but not statistically significant(p>0.05). Rehospitalization rate was higher in group I than in group II. CONCLUSION: Pelvic drainage didn't reduce the postoperative febrile morbidity and lymphocyst formation. Therefore the author could not find any necessity to perform the drainage following radical hysterectomy and pelvic lymphadenectomy.
Drainage*
;
Humans
;
Hysterectomy*
;
Ileus
;
Incidence
;
Lymph Node Excision*
;
Medical Records
;
Serum Albumin
;
Suction
;
Uterine Cervical Neoplasms*
4.Inhibitory Effect of Tetrandrine on Extracellular Matrix Deposition in Rat Hepatic Fibrosis.
Won Young CHOI ; Hyo Jeong CHAE ; Sun Kyung LEE
Korean Journal of Pathology 1999;33(5):319-325
No effective therapy has yet developed for liver fibrosis/cirrhosis by directly inhibiting the accumulation of extracellular matrix. This study was undertaken to determine the effect of tetrandrine in rat model of liver fibrosis induced by carborn tetrachloride (CCl4) administration intraorally. Tetrandrine, a calcium channel blocker, is anti-inflammatory constituent of the families Menispermaceae and Ranunculaceae, which have been used as folk remedies in China. Repeated administration of CCl4 for 14 weeks to rats induced liver fibrosis with steatosis. Rats were killed after 4, 8 or 14 weeks of treatment with CCl4, CCl4 tetrandrine (30 mg/kg) or CCl4 tetrandrine (50 mg/kg). The histopathological findings of liver were observed semi-quantitatively by light microscopy and volume percentage of the collagen deposition was determined by image analyzer. Tetrandrine inhibited collagen deposition induced by CCl4 administration, as shown by less severe steatosis and fibrosis and significantly decreased volume percentage of collagen fibers in CCl4 tetrandrine treated animals compared with CCl4 only group. Thus, the administration of tetrandrine holds great promise for treating subjects with liver fibrosis/cirrhosis as a result of chronic hepatic injury.
Animals
;
Calcium Channels
;
Carbon Tetrachloride
;
China
;
Collagen
;
Extracellular Matrix*
;
Fibrosis*
;
Humans
;
Liver
;
Liver Cirrhosis
;
Medicine, Traditional
;
Menispermaceae
;
Microscopy
;
Models, Animal
;
Ranunculaceae
;
Rats*
5.Interstitial Mononuclear Cell Infiltration and its Phenotypes in IgA Nephropathy.
Hyeon Joo JEONG ; Hyunee YIM ; Sun Hee SUNG ; In Joon CHOI
Korean Journal of Pathology 1994;28(5):506-510
To know the correlation between glomerular and tubulointerstitial lesion and to define the characteristics of interstitial inflammatory cell in IgA nephropathy and classified according to WHO classification and graded tubulointerstitial lesion as mild, moderate and severe. Paraffin-embedded 5u sections were stained with UCHL-l, L26 and CD68 antibodies. More than 20 fields were examined in each case under the high power microscopy and the number of positive cells were counted. There was positive correlation between the severity of glomerular and that of tubulointerstitial lesion. The mostcommoninflammatory cells in the interstitiuin were UCHL-l positive cells followed by CD68 and L26 positive cells. As the WHO grade or tubulointerstitial lesion increased, the numbers of positive cells were increased in all three groups. The proportion of UCHL-1 Positive cells were increased in cases with high WHO grade whereas that of L26 positive cells incases with severe tubulointerstitial lesion Proteinuria was correlated with the degree of inflammatory cell infiltration, especially with that of L26 positive cells.
6.Comparison of the Effects of Morphine Versus Morphine Plus Butorphanol in Epidural Anesthesia for Postoperative Analgesia.
Jeong Soon LEE ; Hyo Jeong KIM ; Hwan Yeong CHOI
Korean Journal of Anesthesiology 1999;36(6):979-984
BACKGROUND: Epidural morphine has been commonly used to provide postoperative pain relief, but it has many side effects such as nausea, vomiting, respiratory depression, and pruritus. The purpose of this study was to evaluate the analgesic efficacy and side effects by combination use of epidural morphine and butorphanol. METHODS: Forty five patients were randomly divided into 3 groups. For group I, a bolus of 4.7 ml of saline and 3 mg of morphine were administered. For group II, a bolus of 4.2 ml of saline and 3 mg of morphine and 1 mg of butorphanol were administered. For group III, a bolus of 3.2 ml of saline and 3 mg of morphine and 3 mg of butorphanol were administered. Continuous epidural analgesia were administered for all groups; group I (saline 99.4 ml and morphine 6 mg), group II (saline 98.4 ml, morphine 6 mg, and butorphanol 2 mg), group III (saline 96.4 ml, morphine 6 mg, and butorphanol 6 mg) by two day infuser, 2 ml/hr. We compared the side effects and analgesic effect of the three groups for 2 days. RESULTS: The incidence of pruritus, nausea and vomiting was reduced significantly in the group II and III, but the incidence of somnolence increased in the group III. There were no significant differences in analgesic effect and the other side effects among the three groups. CONCLUSION: Above results suggest that the addition of butorphanol to morphine in epidural infusion reduce the incidence of pruritus, nausea and vomiting, but increase the incidence of somnolence.
Analgesia*
;
Analgesia, Epidural
;
Anesthesia, Epidural*
;
Butorphanol*
;
Humans
;
Incidence
;
Morphine*
;
Nausea
;
Pain, Postoperative
;
Pruritus
;
Respiratory Insufficiency
;
Vomiting
7.Comparison of the Effects of Morphine Versus Morphine Plus Butorphanol in Epidural Anesthesia for Postoperative Analgesia.
Jeong Soon LEE ; Hyo Jeong KIM ; Hwan Yeong CHOI
Korean Journal of Anesthesiology 1999;36(6):979-984
BACKGROUND: Epidural morphine has been commonly used to provide postoperative pain relief, but it has many side effects such as nausea, vomiting, respiratory depression, and pruritus. The purpose of this study was to evaluate the analgesic efficacy and side effects by combination use of epidural morphine and butorphanol. METHODS: Forty five patients were randomly divided into 3 groups. For group I, a bolus of 4.7 ml of saline and 3 mg of morphine were administered. For group II, a bolus of 4.2 ml of saline and 3 mg of morphine and 1 mg of butorphanol were administered. For group III, a bolus of 3.2 ml of saline and 3 mg of morphine and 3 mg of butorphanol were administered. Continuous epidural analgesia were administered for all groups; group I (saline 99.4 ml and morphine 6 mg), group II (saline 98.4 ml, morphine 6 mg, and butorphanol 2 mg), group III (saline 96.4 ml, morphine 6 mg, and butorphanol 6 mg) by two day infuser, 2 ml/hr. We compared the side effects and analgesic effect of the three groups for 2 days. RESULTS: The incidence of pruritus, nausea and vomiting was reduced significantly in the group II and III, but the incidence of somnolence increased in the group III. There were no significant differences in analgesic effect and the other side effects among the three groups. CONCLUSION: Above results suggest that the addition of butorphanol to morphine in epidural infusion reduce the incidence of pruritus, nausea and vomiting, but increase the incidence of somnolence.
Analgesia*
;
Analgesia, Epidural
;
Anesthesia, Epidural*
;
Butorphanol*
;
Humans
;
Incidence
;
Morphine*
;
Nausea
;
Pain, Postoperative
;
Pruritus
;
Respiratory Insufficiency
;
Vomiting
8.A Case of Congenital Nephrotic Syndrome.
Choong Sun KANG ; Chang Hee HWANG ; PyungKil KIM ; Hyeon Joo JEONG ; In Joon CHOI ; Jung Hye CHOI
Journal of the Korean Pediatric Society 1988;31(5):627-634
No abstract available.
Nephrotic Syndrome*
9.Characterization of Severe Acute Respiratory Syndrome Coronavirus 2Stability in Multiple Water Matrices
Young Jae LEE ; Je Hyoung KIM ; Byeong-Sun CHOI ; Jang-Hoon CHOI ; Young-Il JEONG
Journal of Korean Medical Science 2020;35(36):e330-
The advent of the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates a thorough study of the stability and transmissibility in the environment. We characterized the stability of SARS-CoV-2 in three water matrices: fresh, tap, and seawater. The minimum infective dose of SARS-CoV-2 in Vero cells was confirmed to be 10 3 PFU/mL. The stability of SARS-CoV-2 varied according to the water matrix: infective SARSCoV-2 was undetectable after treatment with fresh water and seawater, but remained detectable for 2 days in tap water, when starting with an initial concentration of 10 4 PFU/mL. When the starting concentration was increased to 10 5 PFU/mL, a similar trend was observed. In addition, viral RNA persisted longer than infectious virus in all water matrices. This study was conducted in stagnant water containing a significantly high titer of virus, thus, human-to-human transmission of SARS-CoV-2 through the actual aquatic environment is expected to be rare.
10.Surgical Clip Moved into the Extrahepatic Bile Duct after Laparoscopic Hepatectomy.
Jong Riul LEE ; Jeong Ho HAN ; Sun Jeong CHOI
Journal of the Korean Society of Endoscopic & Laparoscopic Surgeons 2010;13(2):157-159
In the case of using surgical clips for division of the cystic duct during laparoscopiccholecystectomy, surgical clip migration into the common bile duct is known to be an extremely rare complication. However, its mechanism is currently unclear. The incidence of performing laparoscopic hepatectomy has significantly increased in the laparoscopic center of hospitals. Accordingly, the complications associated with using clips in laparoscopic cholecystectomy have increase as well. A 49 year-old female patient underwent laparoscopic left hepatectomy due to left intrahepatic duct stones with cholangitis. We report here on a case of a clip that migrated into the common bile duct and the duct had bile stones. We also review the relevant literature.
Bile
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Bile Ducts, Extrahepatic
;
Cholangitis
;
Cholecystectomy, Laparoscopic
;
Common Bile Duct
;
Cystic Duct
;
Female
;
Hepatectomy
;
Humans
;
Incidence
;
Surgical Instruments