1.Serological study to determine the optimum age for measles vaccination in Korea.
Gum Ja LEE ; Kon Hee LEE ; Hae Sun YOON
Journal of the Korean Pediatric Society 1991;34(9):1201-1210
No abstract available.
Korea*
;
Measles*
;
Vaccination*
2.A Case of Malignant Ependymoma.
Ja Wook KOO ; Sun Ho LEE ; In Joon SEOL ; Hahng LEE
Journal of the Korean Pediatric Society 1989;32(1):130-136
No abstract available.
Ependymoma*
3.Rapid Detection of Rifampin Resistant Mycobacterium tuberculosis Using the Line Probe Assay.
Mi Kyoung LEE ; Ae Ja PARK ; Hee Sun JEON
Korean Journal of Clinical Pathology 1997;17(2):269-278
BACKGROUND: Tuberculosis continues to be a major threat to health throughout the world, with an estimated 8 to 10 million new cases and 3 million deaths annually. And control of the disease is further threatened by the emergence of drug resistance. Recent major advances have been made in unravelling the molecular basis of M. tuberculosis resistance to isoniazid, streptomycin, quinolones and rifampin. And rifampin resistance is the useful indicator for the occurance of the multi-drug resistance. Hence, the rapid detection of rifampin resistant strain of M. tuberculosis is the key to have successful anti-tuberculosis therapy. Here we present our experience using PCR and line probe assay (INNO-LiPA) for easy and rapid detection of rifampin resistance of M. tuberculosis. METHODS: Thirty rifampin resistant and twenty susceptible strains of M. tuberculosis were collected from the routine culture and analyzed with INNO-LiPA. And results were compared with conventional antibiotic susceptibility testing. After amplification of the region of the RNA polymerase(rpoB), the amplified product is hybridized with a set of 10 oligonucleotides immobilized onto a membrane strip. From the pattern obtained the presence or not of rifampin resistance M. tuberculosis can be assessed. RESULTS: Ninety three percent of patients who had rifampin resistant strain revealed the multidrug resistance while only two showed resistance to rifampin only. The INNO-LiPA test results were generally agreeable with that of the conventional susceptibility testing(90%). The mutations in codon 531 (absence of 55 probe) were most commonly observed. In 55.2% of the 31 rifampin resistance M. tuberculosis confirmed on mutation by R-probes on the INNO-LiPA strips. CONCLUSIONS: The line probe assay after polymerase chain reaction is a fast and convenient method to detect both presence of M. tuberculosis complex strains and its resistance to rifampin in clinical specimens. We have suggested that detection of rifampin resistance may play a key role in monitoring multi-drug resistance. Consequently, the INNO-LiPA test may constitute an important tool for the control of tuberculosis.
Codon
;
Drug Resistance
;
Drug Resistance, Multiple
;
Humans
;
Isoniazid
;
Membranes
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Oligonucleotides
;
Polymerase Chain Reaction
;
Quinolones
;
Rifampin*
;
RNA
;
Streptomycin
;
Tuberculosis
4.A Study on Food Intake and Family Support in Patients with Coronary Artery Disease.
Sun Ja LEE ; Aee Lee KIM ; Young Hee LEE
Journal of Korean Academy of Adult Nursing 2009;21(1):1-12
PURPOSE: This study was to examine the food intake and family support of patients with Coronary Artery Disease(CAD). METHODS: 90 hospitalized patients who received CAD medical treatment were randomly selected. The food intake frequency and family support instrument were utilized. Collected data was analyzed by SPSS/WIN 14.0: t-test, Chi-square-test and Pearson's correlation coefficient. RESULTS: The mean score of food intake frequency was 5.65(total mean score 97.50) which was relatively healthy food intake based on the CAD treatment guidelines. Undesirable food intake items were fruit, fish, milk etc. The mean score of family support was 2.44(range: 1 - 4). Food intake showed a significant(p < .001) positive correlation with family support. There was significant difference(p < .05) on family support according to exercise. There was significant difference(p < .05) on LDL level, one of the CAD risk factors, between first admission patients and readmission patients. CONCLUSION: These findings suggest that nursing intervention education programs should be developed to appropriately care for CHD patients for needed changes.
Coronary Artery Disease
;
Coronary Vessels
;
Eating
;
Fruit
;
Humans
;
Milk
;
Risk Factors
5.The Study of Creatinine Clearance in Neonates.
Dong Sun HONG ; Moon Ja KIM ; Seung Joo LEE ; Keun LEE
Journal of the Korean Pediatric Society 1987;30(2):139-143
No abstract available.
Creatinine*
;
Humans
;
Infant, Newborn*
6.Case of Chronic Pancreatitis Complicated Pancreatic Ascites and Pleural Effusion.
Gye Ja LEE ; Yong Aee CHUN ; Hey Sun LEE ; Yong Mi HONG ; Young Min AHN
Journal of the Korean Pediatric Society 1987;30(1):108-113
No abstract available.
Ascites*
;
Pancreatitis, Chronic*
;
Pleural Effusion*
7.Reversible aplastic anemia due to eild mushroom: a family case.
Youngzoon JUNG ; Kyung Ja HAN ; Kyo Young LEE ; Sang In SHIM ; Sun Moo KIM ; Jong Wook LEE
Korean Journal of Clinical Pathology 1991;11(3):595-599
No abstract available.
Agaricales*
;
Anemia, Aplastic*
;
Humans
8.Acute monocytic leukemia with P-glycoprotein expression.
Hae Kyung LEE ; Kyung Ja HAN ; Kyo Young LEE ; Sang In SHIM ; Sun Woo KIM
Korean Journal of Clinical Pathology 1991;11(2):409-412
No abstract available.
Leukemia, Monocytic, Acute*
;
P-Glycoprotein*
9.Influence of Nurses' Critical Thinking Disposition and Self-Leadership on Clinical Competency in Medium Sized Hospitals
Journal of Korean Clinical Nursing Research 2018;24(3):336-346
PURPOSE: This study was conducted to identify nurses'critical thinking disposition, self-leadership and clinical competency in small to medium sized hospitals less than 300beds. METHODS: Data were collected using the questionnaire from 227 nurses in Incheon city and Gyeonggi province from March to April, 2017. The data were analyzed using t-test, ANOVA and Scheffé's test to identify differences in critical thinking disposition, self-leadership and clinical competency. Pearson correlation coefficients were used to identify the correlation among the study variables, and multiple regression was used to identify factors contributing to clinical competency. RESULTS: There were significant differences in critical thinking disposition according to age, marital status, clinical career, career in currently working department and education about leadership. Significant differences in self-leadership were identified according to marital status, work position, working department, work type, education about leadership, and turnover intention. Clinical competency was significantly different depending on age, education, monthly income, work position, career in currently working department, work type, education about critical thinking disposition and education about leadership. Clinical competency was positively correlated critical thinking disposition and self-leadership. Critical thinking deposition, monthly income and self-leadership explained 30.1% of clinical competency of nurses working in small to medium sized hospitals. CONCLUSION: The results of this study suggest that we need to improve nurses' critical thinking disposition, self-leadership, and the clinical competency.
Clinical Competence
;
Education
;
Gyeonggi-do
;
Incheon
;
Intention
;
Leadership
;
Marital Status
;
Thinking
10.A case of acute eosinophilic leukemia and trisomy 8.
Jung OH ; Kyung Ja HAN ; SangIn SHIM ; Sun Moo KIM ; Jong Wook LEE ; Dong Jip KIM
Korean Journal of Clinical Pathology 1991;11(1):83-87
No abstract available.
Leukemia, Eosinophilic, Acute*
;
Trisomy*