1.Nerve conduction studies of anterior interosseous nerve in healthy adults.
Jae Ho SHIM ; Joong Sun CHON ; Sae Il CHUN ; Jung Soon SHIN
Journal of the Korean Academy of Rehabilitation Medicine 1991;15(4):465-470
No abstract available.
Adult*
;
Humans
;
Neural Conduction*
2.A Case of Effusive-Constrictive Pericarditis in and Infant Treated by Pericardiectomy.
Gee Nam SUN ; Suk Gee KIM ; Min Ho KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1999;32(10):935-938
Effusive-constrictive pericarditis is a very rare disease in infants but has high motality rates when not treated. There were some reports of pericardial constriction associated with intrapericardial abscess that led to pericardiectomy. The patient was admitted due to fever, cyanosis, and abdominal distension. We treated the patient with antibiotics and pericardiostomy but the symtoms did not improved, therefore, pericardiectomy was perfomed immediately. The patient with effusive-constrictive pericarditis was immediately relief on the symptoms and the treatment was successful.
Abscess
;
Anti-Bacterial Agents
;
Constriction
;
Cyanosis
;
Fever
;
Humans
;
Infant*
;
Pericardial Window Techniques
;
Pericardiectomy*
;
Pericarditis*
;
Pericarditis, Constrictive
;
Pericardium
;
Rare Diseases
3.Endoscopic Resection of a Giant Esophageal Lipoma Causing Sudden Choking.
Dong Ho JO ; Hyung Ku CHON ; Sun Ho WOO ; Tae Hyeon KIM
The Korean Journal of Gastroenterology 2016;68(4):210-213
Most esophageal lipomas are discovered incidentally and are small and asymptomatic. However, large (>4 cm) lipomas may cause various symptoms, including dysphagia, regurgitation, or epigastric discomfort. We present a 45-year-old woman with intermittent sudden choking and globus pharyngeus. Upper gastrointestinal endoscopy and endoscopic ultrasound revealed an approximately 10.0×1.5 cm pedunculated subepithelial tumor in the upper esophagus, identified as the cause of her symptoms. A thoracic computed tomography scan revealed a fat attenuated longitudinal mass along the upper esophagus, suggestive of a lipoma. Endoscopic resection of the lesion was performed with a detachable snare to relieve her symptoms, and the pathologic findings were consistent with a lipoma.
Airway Obstruction*
;
Deglutition Disorders
;
Endoscopy
;
Endoscopy, Gastrointestinal
;
Esophagus
;
Female
;
Humans
;
Lipoma*
;
Middle Aged
;
SNARE Proteins
;
Ultrasonography
4.Arthroscopic Treatment of Tibia Intercondylar Eminence Comminuted Fracture Used Number 5-nonabsobable Suture Material.
Je Gyun CHON ; Ho Hyeong PARK ; Chol SONG ; Jae Cheol PARK ; Doo Hoon SUN ; Myung Sang MOON
Journal of the Korean Knee Society 2004;16(2):175-180
PURPOSE: To evaluate effect of modified arthroscopic pull-out suture technique which used number 5-nonabsorbable suture material for tibia intercondylar eminence comminuted fractures. MATERIALS AND METHODS: There were 21 cases of tibia intercondylar emimence fracture which arthroscopic treated at our hospital between 1999 and 2004. However the study population only included 12 cases in which a number 5-nonabsorbable suture material (Ethibond No. 5) was used for tibia intercondylar eminence comminuted fractures and minimum 1-year follow-up has gone. The average follow-up period was 18.5 months (range, 12 to 42 months). Lachman test and KT-2000 athrometer test were evaluated at the pre-and post-operation. Clinical results of all patients were evaluated with the Meyers and Mckeever 's criteria. RESULTS: In all 12 cases, the normal range of motion and sports activities were recovered at the final follow-up. When tested for anterior instability with KT-2000 arthrometer, there were no different between normal knee and operated knee. Clinical results by Meyers and Mckeever's criteria were excellent in 10 patients and good in 2 patients. CONCLUSION: We obtained early mobilization and stable fixation in modified arthroscopic pullout suture technique for tibia intercondylar eminence comminuted fractures. Patients can early return to his job. This technique seems to be one of the effective operative techniques for treatment of tibia intercondylar eminence comminuted fractures.
Arthroscopy
;
Early Ambulation
;
Follow-Up Studies
;
Fractures, Comminuted*
;
Humans
;
Knee
;
Reference Values
;
Sports
;
Suture Techniques
;
Sutures*
;
Tibia*
5.A Latent Autoimmune Diabetes in Adults Patient Manifesting Severe Musculoskeletal Complications.
In Ho YANG ; Sun Hee LEE ; Sang Ouk CHIN ; Suk CHON
Journal of Bone Metabolism 2014;21(4):283-289
Patients with diabetes have many different kinds of complications involving multiple organs, but those involving the musculoskeletal system are relatively uncommon. Diabetic muscle infarction (DMI) is a rare, painful, and potentially serious condition in patients with poorly controlled diabetes mellitus. A 35-year-old man diagnosed with type 2 diabetes eight years ago, visited with severe muscle pain in the right anteromedial thigh without any event of trauma. He had been treated with metformin, but his glycemic control was very poor with a glycated hemoglobin of 14.5%. Evaluation of his painful thigh lesion did not reveal any evidence of infection or vasculitis, but the magnetic resonance imaging and bone scan showed findings of DMI at vastus medialis muscle and an insufficiency fracture at the right medial tibial condyle. He was diagnosed with retinopathy, neuropathy and microalbuminuria but not macrovascular complications. We also diagnosed his diabetes as latent autoimmune diabetes in adults (LADA) based on his low C-peptide level, positive anti-glutamic acid decarboxylase (GAD) antibody and early onset diabetes. Instead of antibiotics, bed rest, analgesics and strict blood glucose control with multiple daily insulin injections led to symptom improvement. This is an unusual case of a young man with LADA experiencing severe musculoskeletal complication of DMI and insufficiency fracture. If a poorly controlled diabetic patient appears to have unaccounted soft tissue pain, musculoskeletal complications such as DMI associated with hyperglycemia should be considered.
Adult*
;
Analgesics
;
Anti-Bacterial Agents
;
Bed Rest
;
Blood Glucose
;
C-Peptide
;
Diabetes Mellitus
;
Diabetes Mellitus, Type 1*
;
Fractures, Stress
;
Hemoglobin A, Glycosylated
;
Humans
;
Hyperglycemia
;
Infarction
;
Insulin
;
Magnetic Resonance Imaging
;
Metformin
;
Musculoskeletal System
;
Myalgia
;
Nociceptive Pain
;
Quadriceps Muscle
;
Thigh
;
Vasculitis
6.Central Venous Catheter Induced Thrombotic Obstruction of the Superior Vena Cava.
Gee Nam SUN ; Min Ho KIM ; Ja Hong KUH ; Jung Koo JO
The Korean Journal of Thoracic and Cardiovascular Surgery 1999;32(9):858-861
Central venous catheterization through subclavian vein has been used for central venous pressure monitoring, hyperalimentation, and fluid therapy. Its complications are air embolism, infection, vascular injury, pneumothorax, hemothorax and thrombosis that is the most serious complication. At the department of Thoracic and Cardiovascular surgery Chonbuk University Hospital, authors experienced superior vena cava syndrome due to thrombosis of the superior vena cava, internal jugular (left), subclavian(left), and innominate vein. Patients was a 21 years old female who had central venous catheterization through subclavian vein for hyperalimentation and fluid therapy because of enterocutaneous fistula. Thrombectomy on superior vena cava was performed, and pre and postoperative anticoagulation therapy was given. Symptoms were relieved after operation. From the venography, performed 6 weeks after the operation, restenosis was seen at the thrombectomy site of the superior vena cava. S anticoagulant and conservative treatment were done that symptoms relieved by the development of collateral venous channel.
Brachiocephalic Veins
;
Catheterization, Central Venous
;
Central Venous Catheters*
;
Central Venous Pressure
;
Embolism, Air
;
Female
;
Fluid Therapy
;
Hemothorax
;
Humans
;
Intestinal Fistula
;
Jeollabuk-do
;
Phlebography
;
Pneumothorax
;
Subclavian Vein
;
Superior Vena Cava Syndrome
;
Thrombectomy
;
Thrombosis
;
Vascular System Injuries
;
Vena Cava, Superior*
;
Young Adult
7.Short term results of Minimally Invasive TKA.
In Soo SONG ; Ho Hyeong PARK ; Je Gyun CHON ; Seung Ki KIM
Journal of the Korean Knee Society 2006;18(1):26-31
PURPOSE: To compare the radiologic and clinical results of patients who had primary total knee arthroplasty(TKA) with 3 different arthrotomy technique: quadriceps-sparing approach(group Ia), minimal incisional approach(group Ib), conventional parapatellar approach(group II). MATERIAL AND METHODS: We assessed 114 patients(142 knees) treated between December 2003 and March 2005(minimal follow-up was one year). Group Ia, Ib and II consisted of 24 patients(32 knees), 23 patients(30 knees) and 67 patients(80 knees). The evaluation included radiologic alignment, skin incision, tourniquet time, blood loss, ambulatory ability and knee score of Hospital for special surgery(HSS). RESULTS: Group Ia and Ib had the results that indicate increased range of motion, shorter length of hospital stay, less skin incision and more tourniquet time. There were no differences between the groups in radiologic alignment, blood loss, and HSS score. CONCLUSION: Although total knee arthroplasty using a minimal incision may provide some early advantages, minimal incision can impede a surgeon's visual field and may influence component alignment. Therefore, these minimal incision approaches should be performed in limited patients with strict indication.
Arthroplasty
;
Follow-Up Studies
;
Humans
;
Knee
;
Length of Stay
;
Range of Motion, Articular
;
Skin
;
Tourniquets
;
Visual Fields
8.Colchicine Derivatives Allows Prolonged Survival of Cardiac Allograft in the Rat.
Young Hak KIM ; Hyung Chang LEE ; Won Sang CHUNG ; Jung Ho KANG ; Hyuck KIM ; Sun Ho CHON ; Sung Ho SHINN
The Korean Journal of Thoracic and Cardiovascular Surgery 2005;38(9):595-600
BACKGROUND: Colchicine with its immunosupressive properties has been used with beneficial effects in autoimmune disease, such as Gout, etc. Whether colchicine, by virtue of the above property, could attenuate the process of cardiac allograft rejection in the rats is investigated in this report. MATERIAL AND METHOD: We compared the untreated group (Control, n=6), Cyclosporin A group (10 mg/kg, daily, n=20), and Colchicine derivative group (Colchicine 40 microgram/kg, n=20) of cardiac allografts in the rats. RESULT: In the untreated control group (n=6), all of 6 rats showed rejection within 3 weeks after cardiac allograft. In the cyclosporin A group (n=20), cyclosporin A (10 mg daily oral dose) was administered at a 10 mg daily oral dose and promoted long-term survival (over 100 days). The cyclosporin A group had one mortality at the 18th post-operative day due to infection. Furthermore, in the Colchicine derivatives group (n=20) with a daily IP (Intra Peritoneum) dose (40 ug/kg/day), we observed long-term survival.(>100 days), except for one rat that died of an anesthetic problem (respiratory failure) at the 9th post-operative day. CONCLUSION: Experiments have also been performed to evaluate whether the effect of colchicine derivatives allowed prolonged survival of cardiac allografts compared with the cyclosporin A administration group in the rats.
Allografts*
;
Animals
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Autoimmune Diseases
;
Colchicine*
;
Cyclosporine
;
Gout
;
Mortality
;
Rats*
;
Virtues
9.Experience of Reoperation after Valve Replacement Using Mechanical Heart Valve: 8 cases.
Hyuck KIM ; Hyung Chang LEE ; Jang Seop WEE ; Jung Ho KANG ; Won Sang CHUNG ; Sun Ho CHON ; Chul Bum LEE ; Young Hak KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2005;38(11):783-787
Eight patients underwvnt reoperation after valve replacement surgery with a mechanical valve from January, 1992 to December, 2003. Among the various indications for reoperation, there were 4 patients with paravalvular leakage; 3 patients underwent resuturing of the area of leakage and one patient underwent redo valve replacement. Among the three patients with stenosis due to thrombosis of the valve, 2 patients underwent redo valve replacement and one patient underwent thrombectomy. In one patient, the valve functioned normally, but stenosis was caused by overgrowth of the patient and redo valve replacement was done 123 months later. There was no postoperative mortality or morbidity. After an average of 51 months (2~134 months) of postoperative follow up, the patients were in good condition and were able to maintain a NYHA functional class of I or II. The operative method used, whether it be a redo valve replacement or valve sparing method, depends upon the type of lesion and the anatomic structure.
Constriction, Pathologic
;
Follow-Up Studies
;
Heart Valves*
;
Heart*
;
Humans
;
Mortality
;
Reoperation*
;
Thrombectomy
;
Thrombosis
10.Sorafenib vs. Lenvatinib in advanced hepatocellular carcinoma after atezolizumab/bevacizumab failure: A real-world study
Young Eun CHON ; Dong Yun KIM ; Mina KIM ; Beom Kyung KIM ; Seung Up KIM ; Jun Yong PARK ; Sang Hoon AHN ; Yeonjung HA ; Joo Ho LEE ; Kwan Sik LEE ; Beodeul KANG ; Jung Sun KIM ; Hong Jae CHON ; Do Young KIM
Clinical and Molecular Hepatology 2024;30(3):345-359
Background/Aims:
Atezolizumab plus bevacizumab (ATE+BEV) therapy has become the recommended first-line therapy for patients with unresectable hepatocellular carcinoma (HCC) because of favorable treatment responses. However, there is a lack of data on sequential regimens after ATE+BEV treatment failure. We aimed to investigate the clinical outcomes of patients with advanced HCC who received subsequent systemic therapy for disease progression after ATE+BEV.
Methods:
This multicenter, retrospective study included patients who started second-line systemic treatment with sorafenib or lenvatinib after HCC progressed on ATE+BEV between August 2019 and December 2022. Treatment response was assessed using the Response Evaluation Criteria in Solid Tumors (version 1.1.). Clinical features of the two groups were balanced through propensity score (PS) matching.
Results:
This study enrolled 126 patients, 40 (31.7%) in the lenvatinib group, and 86 (68.3%) in the sorafenib group. The median age was 63 years, and males were predominant (88.1%). In PS-matched cohorts (36 patients in each group), the objective response rate was similar between the lenvatinib- and sorafenib-treated groups (5.6% vs. 8.3%; P=0.643), but the disease control rate was superior in the lenvatinib group (66.7% vs. 22.2%; P<0.001). Despite the superior progression- free survival (PFS) in the lenvatinib group (3.5 vs. 1.8 months, P=0.001), the overall survival (OS, 10.3 vs. 7.5 months, P=0.353) did not differ between the two PS-matched treatment groups.
Conclusions
In second-line therapy for unresectable HCC after ATE+BEV failure, lenvatinib showed better PFS and comparable OS to sorafenib in a real-world setting. Future studies with larger sample sizes and longer follow-ups are needed to optimize second-line treatment.