No abstract available.
Carcinoma in Situ* ; Cervix Uteri* ; Epithelium* ; Female

No abstract available.
Abdominal Pain*

Epicanthoplasty was performed in 98 patients with the epicanthal fold. Epicanthal fold was classified into three categories-minimal degree, moderate degree, severe degree-according to its severity. In accurate anatomic dissection in medial canthal area, the pathologic mechanism of the formation of the epicanthal fold, I think, are not only the redundancy of skin, but also the early downward insertion of the preseptal and pretarsal portion of orbicularis oculi muscle. A new surgical technique is described for the correction of the epicanthal fold. The procedure is simple to perform and uniformly gives good results.
Humans ; Skin

The DNA ploidy using fresh tissues from 304 cervial cancer were analyzed by flow cytometry in order to evaluate the correlation between DNA ploidy patterns and prognostic factors of uterine cervical cancer. There were l67 diploid cases(55%) and 137 aneuploid(45%). No significant correlation was noted in stage, age and lymph node metastases between diploid and aneuploid tumor. But S-phase fraction and DNA index were higher slightly in cases of lymph node metastases cornpaired to non-metastases. This results suggest that the DNA ploidy cannot be used as an independent prognostic fac- tor, but further evaluation will be needed in order to conclude definite relationship between prognoseic factor and S-phase fraction or DNA index.
Aneuploidy ; Diploidy ; DNA* ; Flow Cytometry ; Lymph Nodes ; Neoplasm Metastasis ; Ploidies ; Uterine Cervical Neoplasms*

Recently, the oncogene and tumor suppressor gene have been recognized as important factors that is contribute to conversion and progression from normal cell to cnacer one. In the current study, expression rates of c-erbB-2 and p53 oncoprotein were analysed in biopsy tissues of uterine cervix to learn whether the expression rates of p53 and c-erbB-2 were related with prognostic factors. The c-erbB-2 and p53 expression rates of group with invasive cervical carcinoma versus control group were 53.6% vs 17.7% and 51.4% vs 9.7%, respectively. There was stastically significant elevation of e-erbB-2 and p53 oncogene expression in patients with invasive cervical carcinoma(p < 0.01). In comparison of invasive cervical carcinoma with CIN, there were stastically significant differences in p53 expression rates(51.4% vs 28.9%) and c-erbB-2 expression rates(53.6% vs 20.2%) and co-expression rates(31.1% vs 6.8%)(p < 0.01). Also in CIN patients, CIN III group showed statistically significant elevation than CIN I and CIN II group(p < 0.01). Among histologic cell types, the expression rate of p53 was higher in sqamous cell carcinoma than in adenocarcinoma. Except for the expression rate of p53 according to histologic cell type, no statistical difference in expression rates of c-erbB-2 and p53 were found according to age, clinical stage, lymph node metastasis in invasive cervical carcinoma(p > 0.05). In conlcusion, c-erbB-2 and p53 oncoprotein are thought to be possible factors in the carcinogenesis of cervical carcinoma and correlate with progression of it. But continuous analysis and follow up of 5 year survival are desirable to determine the role as prognostic factor and correlation with prognostic factors.
Adenocarcinoma ; Biopsy ; Carcinogenesis ; Cervical Intraepithelial Neoplasia* ; Cervix Uteri ; Female ; Follow-Up Studies ; Genes, Tumor Suppressor ; Humans ; Lymph Nodes ; Neoplasm Metastasis ; Oncogenes*

Monostotic Fibrous dysplasia is a relatively rare condition. Three such conditions are experienced at the Dept. of Orthopedic Surgery, Han-II Hospital during the period of September 1970 to June 1972. Two of three cases were involing shaft of left and right tibia respectively, one of which was complicated by pathologic fracture. The third case was on greater trochanter of right femur. All of three cases were treated with curertage and bone graft. Excllent results were obtained.
Femur ; Fibrous Dysplasia of Bone ; Fibrous Dysplasia, Monostotic ; Fractures, Spontaneous ; Orthopedics ; Tibia ; Transplants

Mesenchymal Chondrcsarcoma is a rare malignant tumor originally described by Lichtenstein and Bernstein in 1959. Since the original description, several other reports of this tumor have been published, bringing the total numbers of cases in the literature to about Sixty-five. We report a case of Mesenchymal Chondrosarcoma in an 11-year-old boy who complained of a palpable mass in the region of the left iliac crest.
Child ; Chondrosarcoma, Mesenchymal ; Humans ; Male

The author list should be corrected.

OBJECTIVES: This study was to determine whether drainage after radical hysterectomy and bilateral pelvic lymphadenectomy can reduce the risk of postoperative morbidity as compared with no drainage. METHODS: 165 patients with stage Ia2 to Ilb underwent radical hysterectomy and bilateral pelvic lymphadenectomy between January 1995 and May 1997, and those medical records were analyzed, Closed suction drains were placed in group I (n 102), not in group II (n 67). All surgeries were perforrned by the same surgeon in a uniform method. RESULTS: The characteristics of two groups were similar for mean age, preoperative weight, total protein, serum albumin, tumor cell histology, invasion depth, and tumor stage. There was no difference in mean operation time in two groups. But mean estimated blood loss was more in group I than group lI(p<0.05), Postoperative ileus and postoperative stay was similar in both groups. The incidence of pelvic lymphocyst and febrile morbidity in two groups were comparable with 17% in group I and 27% in poup II, but not statistically significant(p>0.05). Rehospitalization rate was higher in group I than in group II. CONCLUSION: Pelvic drainage didn't reduce the postoperative febrile morbidity and lymphocyst formation. Therefore the author could not find any necessity to perform the drainage following radical hysterectomy and pelvic lymphadenectomy.
Drainage* ; Humans ; Hysterectomy* ; Ileus ; Incidence ; Lymph Node Excision* ; Medical Records ; Serum Albumin ; Suction ; Uterine Cervical Neoplasms*

The clinical role of tumor markers to detect the extent of tumor invasion and recurrence in cervical cancer has been debated. To evaluate the chncal significance of SCC, CEA and TPA as tumor markers in cervical, we studied 744 patients weith cervieal cancer from June 1990 to Mey 1994. The cut-off val ues of SCC, CEA and TPA were 1.5 ng/ml, 4.5 ng/mi and 110 U/I respectively. Followings were the results. 1. The serum concentration and positive rates of SCC before therapy(567 cases) were 3,0+/-7.0ng/ml(40.4%) for stage I,8.7+/-13.9 ng/ml(71.6%) for stage II, 10.8+/-14.7 ng/ml(85.7%) for stage III, 23.9+/-24.3 ng/ml(94.7%) for stage IV, and 13.4+/-19.1 ng/ml(75.0%) for recurrent cancer. It was increased with advancing clinical stage(p<0.01). 2. The seum levels and positive rate of CEA before therapy(627cases) were 3.4+/-4.3 ng/ml (18%) for stage I, 7.1+/-12.3 ng/ml(37.2%) for stage II, 8.4+/-9.6 ng/ml(57.9%) for stage III, 15.4+/-22.2 ng/ml(52.6%) for stage IV, and 10.3+/-16.2 ng/ml(46.4%) for recurrent cancer. It was increased with advancing clinical stage from stage Ito stage III(p<0.01). 3. The serum concentration and positiceive rate of TFA before therapy(301cases) were 51.7+/-53.8 U/l(9.5%) for stage I, 105.3+/-108.8 U/l(32.3%) for stage II, 186.3%+/-159.8 U/l(50%) for stage III, 191.3+/-l06.2 U/I(63.6%) for stage IV, and 135.4+/-117.0 U/l(46.4%) for recurrent cancer. It was increased with advencing clinical stage(p<0.01). 4. In 64 patients{24.2%) with lymph node invasion of 265 patients treated by operation, the mean serum levels of SCC, CEA and TPA were higher than lymph node negative group(p<0.05). 5. The serum levels of SCCand CKA after therepy were 82.8% in sensitivity. 94.3% in specificity, 67.9% in positive predictive value, 97.4% in negative predictive value.
Humans ; Lymph Nodes ; Recurrence ; Sensitivity and Specificity ; Biomarkers, Tumor* ; Uterine Cervical Neoplasms*