1.A Case of Rhinocerebral Mucormycosis in a Diabetic Woman.
Ho Sun JANG ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Annals of Dermatology 1991;3(2):145-152
We report a case of rhinocerebral mucormycosis in a 63-year-old female with a 1-year history of poorly controlled diabetes mellitus. She had black necrotic ulcers on the hard palate, bloody nasal discharge, swelling of the left side of her face, left blepharoptosis, proptosis, and conjunctival injection. Histopathological examination of the palatal lesion showed large, nonseptate, right-angled branching fungal hyphae in the dermis, and Rhizopus species was isolated on Sabouraud's agar media. The patient was treated with a combination of amphotericin B and surgical debridements but died of asphyxia one month after admission. This is a relatively uncommon, opportunistic infection occurring in a diabetic woman, and only several cases are reported in the Korean literature up to date.
Agar
;
Amphotericin B
;
Asphyxia
;
Blepharoptosis
;
Debridement
;
Dermis
;
Diabetes Mellitus
;
Exophthalmos
;
Female
;
Humans
;
Hyphae
;
Middle Aged
;
Mucormycosis*
;
Opportunistic Infections
;
Palate, Hard
;
Rhizopus
;
Ulcer
2.Clinical and Epidemiologic Studies on Childhood Asthma.
Youn Mo AHN ; Sun Ho LEE ; Ha Baik LEE ; Hahng LEE
Journal of the Korean Pediatric Society 1990;33(5):632-641
No abstract available.
Asthma*
;
Epidemiologic Studies*
3.Clinical Efficacy and Tolerability of Terbinafine 1% Cream in Patients with Pityriasis Versicolor.
Ho Sun JANG ; Hyun Tae LEE ; Cheon Gi KIM ; Kyung Sool KWON ; Tae Ahn CHUNG
Annals of Dermatology 1996;8(3):169-176
No abstract available.
Humans
;
Pityriasis*
;
Tinea Versicolor*
;
Treatment Outcome*
4.Efficacy of Intra-Aortic Balloon Pump in Postcardiotomy Cardiogenic Shock.
Jee Won CHANG ; Sun Kyung MIN ; Tae Hee WON ; Jae Ho AHN
The Korean Journal of Thoracic and Cardiovascular Surgery 2002;35(6):449-453
BACKGROUND: Intra-aortic balloon pump (IABP)is well known for its hemodynamic benefit but still has its own complications.Proper use of IABP is the best way t o obt ai n maximum benefit with low complication rate. MATERIALS AND METHOD: Twenty one(men 10,female 11) patients were included in this study among the 100 consecutive adult cardiac surgery patients in our hospital.Eighteen(85.7%)were ischemic heart disease patients.They all received IABP therapy due to postcardiotomy cardiogenic shock according to the well-known indications.Their preoperative conditions,intraoperative factors including hemodynamics, postoperative conditions and IABP-related complications were analyzed. RESULT: Nineteen patients(90.5%)were successfully weaned from IABP.There were 2 patients of operative death and the mortality rate was 9.5%.Duration of IABP use was 40.7+/-24.3 hours.There were 2 cases(9.5%)of IABP-related vascular complications that required surgical intervention. CONCLUSION: We concluded that IABP could be used effectively and safely for postcardiotomy cardiogenic shock patients with low complication rate.
Adult
;
Hemodynamics
;
Humans
;
Mortality
;
Myocardial Ischemia
;
Shock, Cardiogenic*
;
Thoracic Surgery
5.A Study on the Role of Bacteria in the Pathogenesis of Confluent and Reticulated Papillomatosis.
Hyun Tae LEE ; Tae Ahn CHUNG ; Kyung Sool KWON ; Ho Sun JANG ; Chang Keun OH
Korean Journal of Dermatology 1998;36(1):78-85
BACKGROUND: The pathogenesis of confluent and reticulated papillomatosis(CRP) is still unknown, although many theories have been suggested. It is stressed that abnormal host response to colonization of pityrosporum orbiculare might play a role in the pathogenesis of CRP, but is not completely understood. Frequently, we have observed bacterial colonies in the stratum corneum and, especially, within the hair follicles from biopsy specimens of patients with CRP. In addition, successful treatment for CRP with minocycline, a derivative of tetracyclines, has been reported continuously. OBJECTIVE: The purpose of this study was to document the possible association of bacterial factors in the pathogenesis of CRP and to elucidate the effectiveness of minocycline. METHODS: We performed Brown and Brenn gram staining in 12 biopsy specimens, bacterial cultures, identification of microorganisms and antibiotics sensitivity testing including minocycline. We administered oral minocycline with an initial dose of 100mg per day for 1 to 3 months and a maintenance dose 50mg per day for I to 2 months, then evaluated the response of treatment. RESULTS: 1. On Brown and Brenn staining, the gram positive bacterial colonies that stained dark bluish or nearly black were observed within the infundibulum of hair follicles in 10 out of 12 biopsy specimens(83.3%) and on the keratotic invagination of stratum corneum in 11 out of 12 biopsy specimens(91.7%). 2. Histological features of regions where bacterial colonies were observed showed, hyperkeratosis and keratotic invagination on the stratum corneum in all cases. Hyperkeratosis(66.7%), parakeratosis(16.7%), inflammatory cell infiltration(25.0%), perifollicular fibrosis(33.3%), and abnormal keratin in sebaceous ducts(50.0%) were shown in hair follicles. 3. In anaerobic cultures, no bacteria was grown. In aerobic cultures, staphylococcus species were identified in 6 cases, streptococcus viridans in one case, sternotrophomonas maltophilia in one case. In the susceptibiliity test, minocycline was sensitive in 7 from 8 cases. 4. The therapeutic response to minocycline was observed within one month in all cases, and the time to clear the lesions was 1/2 month in 2 cases, 1 month in 4 cases, 2 months in 5 cases, 3 months in one case, respectively. CONCLUSION: Form these results, we suggest that bacterial factors may play an important role in the pathogenesis of CRP and that the action mechanism of minocycline in the treatment of CRP may be due to antibacterial effects.
Anti-Bacterial Agents
;
Bacteria*
;
Biopsy
;
Colon
;
Hair Follicle
;
Humans
;
Malassezia
;
Minocycline
;
Papilloma*
;
Staphylococcus
;
Tetracyclines
;
Viridans Streptococci
6.A Case of Idiopathic CD4 + T Lymphocytopenia Associated with Kaposi's Sarcoma.
Hyun Tae LEE ; Ho Sun JANG ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1997;35(1):191-195
Idiopathic CD4+ T lymphocytopenia (ICL) is a new disease entity characterized by depletion of helper T cells apparently without any evidence of HIV infection. We report a case of ICL associated with Kaposis sarcoma (KS) and pneumocystis carinii pneumonia (PCP) in a 34-year old woman. She developed violaceous, protruding masses on scalp, back, both extremities, palms, soles, left. first toe and peritonsillar region for 2 months. These lesions were confirmed as KS by histopathologic findings. Chest X-ray and HRCT findings represented PCP and KS. Absolute deficiency of CD4+ T cell was detected in the count of T cell subsets. Serologic tests for HIV-1, 2 and HTLV I, -II were negative. And she was absent any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells. By CDC criteria, a diagnosis of ICL was made. Because of aggravation of PCP and lung involuement of KS, she died at 22nd day after admission.
Adult
;
Centers for Disease Control and Prevention (U.S.)
;
Diagnosis
;
Extremities
;
Female
;
HIV Infections
;
HIV-1
;
Humans
;
Lung
;
Lymphopenia*
;
Pneumonia, Pneumocystis
;
Sarcoma, Kaposi*
;
Scalp
;
Serologic Tests
;
T-Lymphocyte Subsets
;
T-Lymphocytes
;
T-Lymphocytes, Helper-Inducer
;
T-Lymphocytopenia, Idiopathic CD4-Positive
;
Thorax
;
Toes
7.A Case of Pedunculated Pigmented Eccrine Poroma Combined with Congenital Melanocytic Nevus on the Scalp.
Kyung Hyung SEO ; Ho Sun JANG ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1997;35(1):169-173
It has been generally assum d that eccrine poroma arises from acrosyringium, the epidermal sweat duct unit. Eccrine poroma mainly involves the non hairy surfaces of the skin, but it has also been found on hair-bearing areas. One of the characteristics of this structure is absence of melanocytes and melanin granules arnong its cells. However a complete absence of melanocytes and melanin granules in eccrine poroma is not invariable and a few reports of such an occurrence have been presented. The authors report herein a case of unusual and rare eccrine poroma. The eccrine poroma had melanin pigment and melanocytes, was pedunculated and occurred on the parietal scalp which was the unusual site of involvement. The eccrine poroma was also combined with a pedunculated congenital melanocytic nevus on the supraauricular scalp.
Melanins
;
Melanocytes
;
Nevus, Pigmented*
;
Poroma*
;
Rabeprazole
;
Scalp*
;
Skin
;
Sweat
8.A case of acute febrile neutrophilic dermatosis associated with ulcerative colitis.
Ho Sun JANG ; Jang Soo LEE ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1991;29(4):522-528
No abstract available.
Colitis, Ulcerative*
;
Sweet Syndrome*
;
Ulcer*
9.Clinical and histopathological observation of confluent and reticulated papillomatosis.
Ho Sun JANG ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1991;29(4):471-480
No abstract available.
Papilloma*
10.A Case of Woringer Kolopp Disease Treated with Topical PUVA.
Jae Bong LEE ; Ho Sun JANG ; Chang Keun OH ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1999;37(2):239-243
A 26-year-old Korean man had an erythematous scaly plaque on his right thigh for fifteen years. He was diagnosed with chronic eczema and treated with topical steroid, but no clinical improvement was obtained for 15 years. Laboratory studies including complete blood cell count, urinalysis, liver and renal function test, and peripheral blood smear were normal. A biopsy specimen showed hyperkeratosis, acanthosis, and mononuclear cellular infiltration in the epidermis. These cells had a perinuclear halo and showed a Pautrier's microabscess like configuration. In the dermis, there was a band like infiltration of inflammatory cells. Infiltrates of the epidermis were negative for leukocyte common antigen(CD45) and positive for Pan T cell(CD45RO). He was treated with topical PUVA twice a week for twelve weeks. Clinical and pathological improvements were obtained. We propose PUVA may be a useful therapeutic modality to treat Woringer Kolopp disease.
Adult
;
Biopsy
;
Blood Cell Count
;
Dermis
;
Eczema
;
Epidermis
;
Humans
;
Leukocytes
;
Liver
;
Pagetoid Reticulosis*
;
Thigh
;
Urinalysis