Lipocortin represents a family of similar Ca++ depentent phospholipid-binding proteins capable of blocking the activity of phospholipase A2 (PLA2) in vitro. Generally, these proteins are believed to inhibit the release of arachidonic acid from photopholipids and the formation of lipid mediators such as prostaglandin, leukotriene, and platelet activating factor. Lipocortin 1, initially identified as a glucocorticoid- responsive protein in macrophages and neutrophils has been implicated in transmembrane signal transduction during growth factor-mediated cell proliferation and transformation. To define the synthesis and its regulation, we investigated the expression of lipocortin 1 in both the mRNA and protein level in U937 cell line in the presence of several differentiation factors. The results were as follows. 1. The expression of lipocortin 1 and its mRNA was increased during TPA-induced differentiation of U937 cells to maximum of 2-fold and 5-fold respectively. Both the protein and mRNA levels decreased after 48 hours. 2. With the treatment with IFN-gamma, the expression of CD16 was increased. However, the protein and mRNA levels of lipocortin 1 were, not changed significantly. 3. Neither the dexamethasone or hydrocortisone have any effects on the expression of lipocortin 1 in both TPA-differentiated and undifferentiated U937 cells. The results from this study would give a light on defining the functional role of lipocortin 1 in macro-moncycle cell lineage and possibly some informative clues for the pathogenic mechanisms of the inflammatory diseases.
Annexin A1* ; Annexins* ; Arachidonic Acid ; Cell Lineage ; Cell Proliferation ; Dexamethasone ; Humans ; Hydrocortisone ; Macrophages ; Neutrophils ; Phospholipases A2 ; Platelet Activating Factor ; RNA, Messenger ; Signal Transduction ; U937 Cells*

True cysts of the pancreas are rare, and enterogeous (duplication) cysts are extremely rare. We describe a case of enterogenous cyst of the pancreas located in the retroperitoneum, in which homogenous low attenua-tion, multiloculation, internal septation and cyst wall calcification were noted.
Pancreas*

The aim of this study was to investigate the perception of students, their parents, and nutrition teachers regarding environment-friendly foods (EFF) and the satisfaction with school meals at elementary schools. Questionnaires were sent to nutrition teachers at five elementary schools located in the Jindo area, Jeonnam province, and were distributed to students and their parents. A total of 351 questionnaires from students and 334 from parents were collected from March to April, 2013. In addition, 43 nutrition teachers/dietitians working at elementary schools in the Jindo area responded to questionnaires. Nutrition teachers primarily recognized the classification and certification standards of EFF, and verified the certification mark of EFF when they purchased foods. However, 13.4% of students and 38.6% of parents replied as 'know well' regarding the classification and certification standards of EFF and they verified the mark of EFF less often than the nutrition teachers (p < 0.001). Most of the nutrition teachers and parents indicated 'safety' as the main advantage of EFF. The students and parents were satisfied with EFF at home and school meals because of the safety and favorable effect on health. The results showed that EFF compromised 20~40% of monthly food costs for 51.1% of nutrition teachers. The overall score for satisfaction with school meals for students was 3.88 based on a 5-point Likert scale; however, that of the parents was 3.72. The nutrition teachers realized that the parents were more interested in EFF and satisfied with EFF than the students. The major barriers to using EFF in school meals were 'lack of information about EFF' and 'unstable supply.' Therefore, the above results suggested that there should be improvement in the supply of EFF to include more EFF in school meals and efforts should be made to provide students and parents with more information for understanding EFF.
Certification ; Humans ; Imidazoles ; Meals ; Nitro Compounds ; Parents ; Surveys and Questionnaires

PURPOSE: The purpose of this study was to identify the factors influencing sexual assertiveness in dating college students. METHODS: With a cross-sectional survey design, 468 college students who have had dating experiences were recruited and answered questionnaires. Data were analyzed using t-test, ANOVA with Scheffe? test, Pearson's correlation coefficients, and multiple regression. RESULTS: The sexual assertiveness of college students showed significant results: positive correlations with self-assertiveness and negative correlations with traditional sexual attitude, gender role stereotypes. Significant predictors of sexual assertiveness were traditional sexual attitude, gender role stereotypes, and self-assertiveness. These variables explained 37% of the variance in sexual assertiveness. CONCLUSION: Findings suggest that it is important to identify and improve communication patterns in relation to sexual assertiveness. There is a need for sex education programs for college students that are relevant and effective.
Assertiveness ; Cross-Sectional Studies ; Gender Identity ; Humans ; Surveys and Questionnaires ; Sex Education

PURPOSE: This study investigates nurses' organizational commitment, internal marketing, and occupational satisfaction depending on their age, martial status, clinical experience and income. METHODS: The subjects of this study were 350 nurses from six hospitals in Jeolla-do. The t-tests were used to analyze the differences in internal marketing, occupational satisfaction, and organizational commitment depending on their age, marital status, career, and income. The relationships among internal marketing, occupational satisfaction, and organizational commitment were analyzed by the path analysis. RESULTS: The results of this study showed that organizational commitment was correlated with age, clinical experiences, and income, but not significantly associated with martial status. Education and training policy, benefit system, and fairness of the internal marketing were influencing factors on occupational satisfaction. These factors were correlated with organizational commitment through occupational satisfaction. CONCLUSION: This study addressed the relationships among nurses' internal marketing, occupational satisfaction, and organizational commitment. Based on the results, it is suggested that hospital organizations introduce more diverse incentive policies to enhance nurses' occupational satisfaction and organizational commitment.
Marital Status ; Marketing ; Motivation

PURPOSE: The purpose of this study was to identify the effects of eating habits, activities of daily living and health behaviors on oral health related-quality of life in elders. METHODS: The sample consisted of 246 people 65 years or older. Data were analyzed using frequency, percentage, average standard deviation, t-test, ANOVA, Scheffe, Pearson Correlation Analysis and Hierarchical Multiple Regression. RESULTS: The control variables such as gender, presence of a spouse, subjective health status, presence of chronic disease and existing number of teeth explained 14% (F=7.76, p<.001) of variance in oral health related-quality of life. The control variables, eating habits, activities of daily living and health behaviors collectively explained 20% of variance in oral health related quality of life. CONCLUSIONS: The factors that influence oral health related quality of life were presence of spouse presence factor, existing number of teeth and health behavior. Therefore, oral health related quality of life of elders requires the development of programs to boost the quality of life, and help the elderly people to maintain existing number of teeth by focusing on the variety of characteristics.
Activities of Daily Living ; Aged ; Chronic Disease ; Eating ; Health Behavior ; Humans ; Oral Health ; Quality of Life ; Spouses ; Tooth

The purpose of this study was to investigate the level of anxiety for the mothers of leukemic children and to provide the fundamental data for the better performance of caring to them. The subject were 292 mothers : 100 mothers whose children had a leukemia, 80 mothers whose children had taken a tonsillectomy, 112 mothers whose children with medical disease except cancer. The data were collected through the state-Trait Anxiety Inventory of Spilberger and analyzed by t-test, ANOVA, Scheffe test. The results were as follows ; 1. The state anxiety mean score of mothers with leukemic children was 54.16. 2. The state anxiety of mothers with leukemic children was higher than that of the rest (F=8.00, P=0.0004). 3. There was no significant difference in anxiety of mothers with leukemic children in relation to leukemic children's and their mother's general characteristics.
Anxiety* ; Child* ; Humans ; Leukemia ; Mothers* ; Tonsillectomy ; Child Health

Many studies for LPS-induced cytokines, chemokines gene expressions have been reported, but results are highly diverse. The dose of LPS used, cell type studied or other technical factors may contribute to the differences. We investigated the cytokine mRNA expressions, interleukin-2 (IL-2), IL-6, IL-10 and IFNr, on thioglycollate (TG) elicited-mouse peritoneal macrophages stimulated with various concentrations, 1 ng/ml, 10 ng/ml, 100 ng/ml, 1 ug/ml and 10 ug/ml, of LPS used by reverse transcription polymerase chain reaction (RT-PCR) and northern blot analysis. TG- elicited peritoneal macrophages expressed IL-6 and IFN-r mRNA in a dose-dependent manner. The expressions of IL-2 and IL-10 mRNA were dose-independent manner. In northern blot analysis, IL-6 mRNA expression was detected only in 10 ug/ml LPS concentration for short stimulation time (0.5 h), while IL-10 mRNAs were expressed evenly in all LPS concentrations. The expression of IL-6 mRNA was sustained until 72 h at 10 ug/ml concentration only, but IL- 10 mRNAs of all cases of LPS concentrations were sustained evenly until then. These results suggest that the concentration of LPS required for cytokine induction must be determined differently from gene to gene types, and although LPS concentration 10 ug/ml has not been used as an ordinary concentration in vitro cytokine study, 10 ug/ml of LPS might be more appropriate concentration in the study of IL-6 expression on mouse peritoneal macrophages.
Animals ; Blotting, Northern ; Chemokines ; Cytokines ; Gene Expression ; Interleukin-10 ; Interleukin-2 ; Interleukin-6 ; Macrophages, Peritoneal* ; Mice* ; Polymerase Chain Reaction ; Reverse Transcription ; RNA, Messenger*

PURPOSE: The Purposes of this study were to examine the effects of Koryo-Sooji-Chim (30minutes * 2times/week * 2weeks) on menstrual pain and menstrual symptoms of female university students with dysmenorrhea. METHOD: The subjects were 22 female students with dysmenorrhea, 12 experimental group, 10 control group, studying at K university in Chungnam province. The data were collected through questionnaires from September 1st to November 30th 2003 were analyzed using descriptive statistics, X2-test, Fisher's exact test and Mann-Whitney test. RESULT: 1. The menstrual pain scores were significantly different between the two groups(U=16.0, p=.001). 2. The menstrual symptom scores were significantly different between the two groups(U=28.5, p=.038). CONCLUSION: These findings showed that Koryo-Sooji-Chim was effective related to menstrual pain and menstrual symptoms of female university students with dysmenorrhea. Koryo-Sooji-Chim during dysmenorrhea could be applied as an effective nursing intervention.
Chungcheongnam-do ; Dysmenorrhea* ; Female ; Female* ; Humans ; Nursing ; Surveys and Questionnaires

Angiogenesis is an essential requirement for development, progression, and metastasis of malignant tumors. Vascular endothelial growth factor (VEGF) is one of the important angiogenic factors. Recently the role of angiogenesis has been known in premalignant lesions. This study was performed to determine whether the angiogenesis and VEGF expression were increased in association with histological grade of cervical intraepithelial neoplasia (CIN) and to see the relationship between the angiogenesis and VEGF. Immunostainings for factor VIII and VEGF were performed on 52 cases of cervical neoplasia (12 cases of CIN I, 11 cases of CIN II, 15 cases of CIN III, 7 cases of microinvasive squamous cell carcinoma, and 7 cases of invasive carcinoma) and 5 cases of normal cervix. The results showed a significant increase of microvessel count from normal cervix through CIN grades to invasive squamous cell cacinoma. VEGF expression was increased in proportion to the CIN grades. There was no significant correlation between microvessel count and VEGF expression. In conclusion, the tumor angiogenesis is an early event in tumorigenesis of uterine cervix. In addition, no significant relationship between the microvessel count and VEGF expression in CIN suggests the possibility of other growth factors affecting mainly angiogenesis of premalignant lesion of uterine cervix.
Angiogenesis Inducing Agents ; Carcinogenesis ; Carcinoma, Squamous Cell ; Cervical Intraepithelial Neoplasia* ; Cervix Uteri ; Factor VIII ; Female ; Intercellular Signaling Peptides and Proteins ; Microvessels ; Neoplasm Metastasis ; Vascular Endothelial Growth Factor A*