OBJECTIVE: The objective of this study was to assess the association between women with endometriosis and risk of preterm birth. METHODS: Two reviewers independently determined all prospective cohort study, retrospective cohort study, large population based cohort study, retrospective secondary analysis, and double blinded, multicentric, observational and cohort study, placebo-controlled, randomized clinical trial published using PubMed, Medline, Korea Education and Research Information Service, and Scopus from March 1994 through February 2016 without language restrictions comparing obstetric outcomes women with endometriosis and women without endometriosis. The meta-analysis was performed following the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. Six studies met inclusion criteria, including 50,472 women. Among 50,472 pregnancies, 39,659 had endometriosis and 10,813 had no endometriosis. Meta-analyses were estimated with odds ratios and 95% confidence intervals using random effect analysis according to heterogeneity of studies. RESULTS: Data from six effect sizes from six studies involving 50,472 patients were enrolled. These meta-analyses showed women with endometriosis have an increased risk of preterm birth (odds ratio, 1.473; 95% confidence interval, 1.216 to 1.785). CONCLUSION: These meta-analyses demonstrate women with endometriosis at pregnancy have an increased risk of preterm birth. Therefore, it is worthy for obstetrics to increase the careful inspection in women with endometriosis during pregnancy.
Cohort Studies ; Education ; Endometriosis* ; Female ; Humans ; Information Services ; Korea ; Obstetrics ; Odds Ratio ; Population Characteristics ; Pregnancy ; Premature Birth* ; Prospective Studies ; Retrospective Studies

PURPOSE: This study identified the prevalence of depressive symptoms and explored correlates of depressive symptoms among Korean women care-workers caring older adults living in community. METHODS: A total of 465 participants were recruited for the study. Depressive symptoms was measured by the CES-D10 and distress was assessed using a single question given 5 Likert scale. RESULTS: The prevalence of depressive symptoms and distress among care-workers were 32.5% and 32.0% respectively. Work environment safety, violence exposure experience, work-family conflict, weekly care work time, and poor health status were significantly associated with depressive symptoms. Only violence exposure experience and poor health status were associated with distress. CONCLUSION: Our findings suggest more attention on mental health of care-workers and their risky work condition such as violence.
Adult* ; Depression* ; Exposure to Violence ; Female ; Humans ; Mental Health ; Prevalence ; Violence

Iron-induced oxidative stress has been emphasized in the pathomechanism of Parkinson's disease (PD). Studies on the distribution of iron in the parkinsonian postmortem brain have demonstrated that iron deposition is selectively increased in substantia nigra pars compacta (SNc). This study was done to examine the alteration of nigral iron and ferritin in an animal model of parkinsonism and to understand the role of disturbed iron metabolism as a cause of PD. Hemiparkinsonian model was made by stereotaxically injecting 6-OHDA into the SN of Sprague-Dawley rats. We measured the content and distribution of iron by Perls' staining, and ferritin by immunohistochemical method in the SN. The H & E. cresyl violet, and immunocytochemical stain for glial fibrillary acidic protein, tomato lectin, and cabonic anhydrase-II were done to characterize the exact cell types. Iron content was markedly increased in the hemiparkinsonian model of SNc, not reticulate where normally more iron is distributed. The increased ferritin immunoreactivity was located in the same iron rich area of SNc. The cells with increased iron and ferritin were mainly astrocytes and microglias. 6-OHDA injection into SN resulted in increased free iron and ferritin immunoreactivity, suggesting that iron is important participant in oxidative cell death in PD. We think that increased ferritin in 6 OHDA lesioned SN argues against the hypothesis that decreased ferritin is a prerequisite for the free radical mediated death of nigral neurons in this model.
Animals ; Astrocytes ; Brain ; Cell Death ; Ferritins* ; Glial Fibrillary Acidic Protein ; Iron* ; Lycopersicon esculentum ; Metabolism ; Microglia ; Models, Animal ; Neurons ; Oxidative Stress ; Oxidopamine* ; Parkinson Disease ; Parkinsonian Disorders ; Rats* ; Rats, Sprague-Dawley ; Substantia Nigra ; Viola

PURPOSE: This study examined relationships among stress, stress coping strategies, and somatization in mothers-in-law from multi-cultural families in a rural area. METHODS: Elderly mothers-in-law (n=227) living with foreign daughters-in-law completed a self-reporting questionnaire. Data were collected from April to August 2009. Questions related to stress (Visual Analog Scale, VAS), coping strategies (Coping Strategy Scale) for stress, and somatization (Symptom Check List 90, Revised). SPSS/WIN 12.0 program was used for descriptive analysis, t-test, one-way ANOVA, Pearson correlation, and multiple regression analyses. RESULTS: Subjects had a moderate level of stress (5.03). There were significant differences in stress level according to age, educational level, religion, chronic disease, health status, number of children, agreement of an international marriage of her sons, satisfaction in living with a foreign daughter-in-law, and family conflict. Stress showed a significant positive correlation with offensive coping strategy, passive strategy, and somatization. Stress, offensive coping strategy, and passive coping strategy affected the level of somatization. CONCLUSION: In a family situation involving co-habitation of mother- and foreign daughter-in-law, increased stress experienced by the mother-in-law can lead to increased offensive and passive coping strategies, and increased somatization. More effective means of stress reduction are needed for mothers-in-law from multi-cultural families.
Adaptation, Psychological ; Aged ; Child ; Chronic Disease ; Family Conflict ; Humans ; Marriage ; Somatoform Disorders ; Surveys and Questionnaires

PURPOSES: The purposes of this study were to examine knowledge related to child abuse, attitudes toward child abuse, and intention to report child abuse and to identify the predictors of nurses' intention to report child abuse. METHOD: A descriptive-correlational study was conducted. Participants were 171 nurses who worked in the pediatric or emergency rooms in G city. Self-administered questionnaire was used for data collection. Descriptive statistics, t-test or ANOVA, Pearson correlation, and stepwise multiple regression analysis were used for data analysis. RESULTS: Nurses had a limited knowledge related to child abuse. Nurses had negative attitudes toward child discipline, were inclined to punish the abuser, and had positive attitudes about professional responsibility for reporting child abuse. Nurses perceived difficulty in the actual behavior of reporting child abuse. Nurses' intention to report child abuse was predicted by nurses' attitudes to professional responsibility for reporting child abuse. CONCLUSIONS: Based on the findings of this study, educational programs need to be developed, implemented, and evaluated. The conclusion of this study is that supplementary education is needed for multidisciplinary decision making concerning the role of the nurses within the context of child abuse.Implications for nursing practice, education and research are discussed.
Child ; Child Abuse* ; Child* ; Data Collection ; Decision Making ; Education ; Emergency Service, Hospital ; Humans ; Intention* ; Nursing ; Statistics as Topic ; Child Health ; Surveys and Questionnaires

Purpose: The purpose of this study was to construct a model that describes the health related quality of life in working women with preschool children and to verify the goodness of fitness of the model. Methods: The data were collected with a structured self-report questionnaire from 483 working women with preschool children. Results: The modified model showed a reasonable fitness to the data. Social support, job satisfaction, parenting stress, sense of coherence and depression accounted for 78% of the health related quality of life in working women with preschool children. Conclusion This study suggests that the health related quality of life in working women with preschool children can be improved by reducing parenting stress and depression level, and by increasing social support, job satisfaction, and sense of coherence. Depression can also be managed by reducing parenting stress and by increasing job satisfaction and sense of coherence. Based on the results of this study, it is necessary to develop intervention programs to increase the health related quality of life or to decrease depression in working women.

No abstract available.

Glassy cell carcinoma is a histologic subtype of cervical cancer with distinct pathologic features and it has an aggressive biologic course. It was first described by Glucksmann and Cherry in 1956 as a poorly differentiated adenoquamous carcinoma and commented on its poor prognosis, unresponsiveness to traditional modes of therapy, and often associated with pregnancy. The characteristic histologic features are defined as follows: 1) cells with a moderate amount of cytoplasm resembling ground glass, 2) a fairly distinct cell membrane that stains with eosin or PAS, 3) large nuclei with prominent nucleoli. We present two cases of glassy cell carcinoma of the cervix successfullyl treated by neoadjuvant chemotherapy and radical hyterectorny, with a brief review of literatures.
Cell Membrane ; Cervix Uteri* ; Coloring Agents ; Cytoplasm ; Drug Therapy* ; Eosine Yellowish-(YS) ; Female ; Glass ; Hysterectomy* ; Pregnancy ; Prognosis ; Prunus ; Uterine Cervical Neoplasms

No abstract available.
Cough* ; Humans ; Sarcoidosis* ; Skin*

Pigmented squamous cell carcinoma is a very rare malignant, pigmented, epidermal tumor. The rarity of pigmented squamous cell carcinomas may reflect in part their misdiagnosis as other pigmented neoplasms, particularly malignant melanoma. To our knowledge, only five cases have been reported in literature. We recently experienced a case of pigmented squamous cell carcinoma arising from pigmented actinic keratosis in a 77 years old female. Physical examination showed a 0.8 0.6 cm, smooth, dark brown pigmented patch with irregular but sharply defined borders located on the upper left chest. The biopsy specimen showed histologic findings of pigmented actinic keratosis with abundant melanin pigments, which became pigmented squamous cell carcinoma. Most of pigments in the squamous cell carcinoma were contained within the melanocytes along with the neoplastic squamous cells.
Actins* ; Aged ; Biopsy ; Carcinoma, Squamous Cell* ; Diagnostic Errors ; Female ; Humans ; Keratosis, Actinic* ; Melanins ; Melanocytes ; Melanoma ; Physical Examination ; Skin ; Thorax