PURPOSE: To determine the value of magnetic resonance imaging(MR) and magnetic resonance angiography(MRA) inassessing collateral vessels of moyamoya disease. MATERIALS AND METHODS: Twenty-four patients with moyamoyadisease who underwent MR, 3D TOF MRA, and conventional angiography participated in this study. Two radiologistsworking independently and with no knowledge of the angiographic findings, interpreted the MR and MRA images. Todetermine the presence of parenchymal and leptomeningeal collaterals(48 hemispheres) and transdural collaterals(38hemispheres in 19 patients were depicted by angiography of the external carotid), the findings were compared withthose of angiography. RESULTS: Parenchymal, leptomeningeal, and transdural collaterals were depicted byconventional angiography in 34(71%), 32(67%), and 11(29%) hemispheres respectively. The sensitivity andspecificity of MR/MRA for collateral vessels were 79.1/ 88.1% for parenchymal collaterals, 72.1/ 88.1% forleptomeningeal collaterals, and 0.1/18.1% for transdural collaterals, respectively. Respective sensitivity andspecificity of MR/MRA were 88.94/94.1% for leptomeningeal collaterals, and 18.93/55.1% for transdural collaterals,when the prominent posterior cerebral and external carotid artery were regarded as secondary signs ofleptomeningeal and transdural collateral vessels. CONCLUSION: In moyamoya disease, MR and MRA are useful imagingmodalities for the assessment of collateral vessels. The prominent posterior cerebral artery and external carotidartery can be useful secondary signs of leptomeningeal and transdural collateral vessels.
Angiography* ; Carotid Artery, External ; Cerebral Angiography ; Humans ; Moyamoya Disease* ; Posterior Cerebral Artery

OBJECTIVE: This study was performed to determine the anatomical landmarks and optimal dissection points of the facial nerve (FN) and the hypoglossal nerve (HGN) in the submandibular region to provide guidance for hypoglossal-facial nerve anastomosis (HFNA). METHODS: Twenty-nine specimens were obtained from 15 formalin-fixed adult cadavers. Distances were measured based on the mastoid process tip (MPT), common carotid artery bifurcation (CCAB), and the digastric muscle posterior belly (DMPB). RESULTS: The shortest distance from the MPT to the stylomastoid foramen was 14.1+/-2.9 mm. The distance from the MPT to the FN origin was 8.6+/-2.8 mm anteriorly and 5.9+/-2.8 mm superiorly. The distance from the CCAB to the crossing point of the HGN and the internal carotid artery was 18.5+/-6.7 mm, and that to the crossing point of the HGN and the external carotid artery was 15.1+/-5.7 mm. The distance from the CCAB to the HGN bifurcation was 26.6+/-7.5 mm. The distance from the digastric groove to the HGN, which was found under the DMPB, was about 35.8+/-5.7 mm. The distance from the digastric groove to the HGN, which was found under the DMPB, corresponded to about 65.5% of the whole length of the DMPB. CONCLUSION: This study provides useful information regarding the morphometric anatomy of the submandibular region, and the presented morphological data on the nerves and surrounding structures will aid in understanding the anatomical structures more accurately to prevent complications of HFNA.
Adult ; Cadaver ; Carotid Artery, Common ; Carotid Artery, External ; Carotid Artery, Internal ; Facial Nerve ; Humans ; Hypoglossal Nerve ; Mastoid ; Muscles

No abstract available.
Breast Neoplasms* ; Breast* ; Diagnosis*

PURPOSE: This study was conducted to improve the Korean influenza management system and to determine the status of influenza vaccination in some community health centers through a survey of the officers in charge of influenza vaccination. METHODS: The authors conducted a questionnaire survey by e-mail for the officers in charge of influenza vaccination of 8 community health centers in Daegu-si, 5 community health centers in Ulsan-si and 25 community health centers in Gyeongsangbuk-do. The authors developed a questionnaire including selection methods of the influenza vaccination objects, results of influenza vaccination in 2002, problems of influenza vaccination, the population within the respondents`jurisdiction and so on. RESULTS: The proportion of influenza vaccination at community health centers among all residents in the 2002-2003 influenza season was 3.8% in Daegu-si, 14.8% in Ulsan-si, 15.1% in urban Gyeongsangbuk-do and 24.9% in rural Gyeongsangbuk-do. The proportion of influenza vaccination at community health centers among priority cases for vaccination was 12.9% in Daegu-si, 43.1% in Ulsan-si, 39.3% in urban Gyeongsangbuk and 41.6% in rural Gyeongsangbuk-do. The officers in charge of influenza vaccination stated that the problems of influenza vaccination were deficiencies in preparatory examination such as manpower shortage. Twenty-five persons stated as a problem that influenza vaccinations conducted in the hospitals were hardly reported, and fifteen of these clarified that this was due to hospital indifference. CONCLUSIONS: The authors examined all community health centers of Daegu-si, Ulsan-si, and Gyeongsangbuk-do, and investigated the vaccination states and problems that health officers were dealing with. Therefore, this study is meaningful with its basic data for the management of domestic influenza vaccination.
Community Health Centers* ; Electronic Mail ; Gyeongsangbuk-do ; Humans ; Influenza, Human* ; Seasons ; Vaccination* ; Surveys and Questionnaires

PURPOSE: To access the usefulness of magnetic resonance(MR) in the evaluation of orbital blowout fracture. MATERIALS AND METHODS: Fourteen patients with orbital blow out fractures diagnosed by plain radiography(n = 8) or computed tomography(CT)(n = 6) were examined with MR. Twenty blowout fractures including six patients with two lesions were presented and the fracture site of the orbit was the medial wall in 11 cases and the orbital floor innine cases. MR images in nine cases of six patients could be compared with CT scans. On MR images, were trospectively evaluated the presence of fracture, herniation of orbital fat, abnormality of extraocular muscle, intraorbital hematoma and intrasinus hemorrhage. In nine cases we also compared these findings with CT scans. RESULTS: Eighteen orbital blowout fractures with fat herniation could be diagnosed on MR images. In only nine of these 18 cases, the fracture itself could be seen on MR images as a disruption of the orbital wall, which produce a signal void. But two blow out fractures without orbital fat herniation, seen on CT, were not detected on MRimages. Twenty abnormalities of extraocular muscle in 18 cases were depicted on MR images. There were nosignificant differences between MR and CT in the evaluation of orbital fat herniation and extraocular muscle abnormality ; however, in one case oblique sagittal MR images provided more useful information about the status ofthe inferior rectus muscle. Intraorbital hematoma was detected by MR in three patients. We were able to establish the presence of intraorbital hematoma by using the different signal intensities from fat or muscle on T1- and/or T2-weighted images. MR was found to be superior to CT in one case of intraorbital hematoma because of the iso-density of hematoma compared to muscle. MR also detected intrasinus hemorrhage which on T1-weighted images revealed high signal intensity in ten cases. MR was more valuable in demonstrating intrasinus hemorrhage in onecase where a CT scan showed only hypodense fluid. CONCLUSION: MR is a useful diagnostic modality in the evaluation of orbital blowout fracture with orbital fat herniation. Compared with CT, it also provides more valuable information about associated extraocular muscle abnormality, subacute hemorrhage in the orbit and paranasal sinus.
Hematoma ; Hemorrhage ; Humans ; Orbit* ; Tomography, X-Ray Computed

OBJECTIVES: Even though several epidemiological studies have observed positive associations between blood lead levels and homocysteine, no study has examined whether this association differs by the levels of micronutrients, such as folate, vitamin B6, and vitamin B12, which are involved in the metabolism of homocysteine. In this study, we examined the interactions between micronutrients and blood lead on homocysteine levels. METHODS: This study was performed with 4089 adults aged > or =20 years old in the US general population using the National Health and Nutrition Examination Survey 2003-2004. RESULTS: There were significant or marginally significant interactions between micronutrients and blood lead levels on mean homocysteine levels. Positive associations between blood lead and homocysteine were clearly observed among subjects with low levels of folate or low vitamin B6 (p-trend <0.01, respectively). However, in the case of vitamin B12, there was a stronger positive association between blood lead and homocysteine among subjects with high levels of vitamin B12, compared to those with low levels of vitamin B12. In fact, the levels of homocysteine were already high among subjects low in vitamin B12, irrespective of blood lead levels. When we used hyperhomocysteinemia (homocysteine>15 micromol/L) as the outcome, there were similar patterns of interaction, though p-values for each interaction failed to reach statistical significance. CONCLUSIONS: In the current study, the association between blood lead and homocysteine differed based on the levels of folate, vitamin B6, or vitamin B12 present in the blood. It may be important to keep sufficient levels of these micronutrients to prevent the possible harmful effects of lead exposure on homocysteine levels.
Adult ; Aged ; Female ; Folic Acid/blood ; Homocysteine/*blood ; Humans ; Lead/*blood ; Male ; Micronutrients/*blood ; Middle Aged ; Nutrition Surveys ; Odds Ratio ; United States ; Vitamin B 12/blood ; Vitamin B 6/blood

In this study we present a case of an angiocentric T-cell lymphoma (ACTL) which involve the esophagus. A 37-year-old male was admitted with dysphagia, odynophagia, and weight loss for 3 months. Two months before his admission, he had undergone on endoscopy with a biopsy. The first endoscopic findings revealed a large ulcerative lesion on the esophagus, although there had been no evidence of lymphoma upon microscopic examination. On the follow up endoscopic examination, this ulcerative lesion revealed progressive and destructive change. Histopathology of the third biopsied specimens showed large atypical lymphocyte infiltrates with angiocentric and angioinvasive features. Immunohistochemical studies revealed that the atypical (large) lymphocytes had T-cell phenotypes (CD3+, CD5+, and CD43+) and contained few reactive B-cells (CD20+), We assume that this is the first case of ACTL involving the esophagus and larynx.
Adult ; B-Lymphocytes ; Biopsy ; Deglutition Disorders ; Endoscopy ; Esophagus* ; Follow-Up Studies ; Humans ; Larynx ; Lymphocytes ; Lymphoma ; Lymphoma, T-Cell* ; Male ; Phenotype ; T-Lymphocytes* ; Ulcer ; Weight Loss

Extramedullary plasmacytoma of the gallbladder is extremely rare. A review of the literature in English revealed only one case, involving a patient with initial extramedullary plasmacytoma of the maxillary sinus. In this report, we describe the case of a 63-year-old man with surgically confirmed extramedullary plasmacytoma confined to the gallbladder. At ultrasonography and computed tomography, diffuse and uniform thickening of the gallbladder wall without evidence of surrounding tissue infiltration was depicted.
Gallbladder* ; Humans ; Maxillary Sinus ; Middle Aged ; Plasmacytoma* ; Ultrasonography

BACKGROUND: This study was performed to evaluate the effect of group intervention by primary care physicians on the changes of drinking behaviors in Korean heavy drinkers. METHODS: A total of 32 male heavy drinkers participated in group intervention by family physicians of Chungnam National University Hospital. Initially, they were assessed for general characteristics, family function and drinking characteristics prior to the intervention conducted 4 times (about 40 minutes/each session). Reassessment on their drinking frequencies (times/week), drinking amounts (drinks/drinking day) and Alcohol Use Disorders Identification Test (AUDIT) score was achieved at directly, at 12 weeks and at 1 year after intervention. RESULTS: The mean drinking frequency was significantly (P < 0.01) decreased from 5.2 +/- 1.7 before to 3.5 +/- 2.4 at directly, 3.9 +/- 2.3 at 12 weeks and 4.0 +/- 2.3 at 1 year after intervention. The mean drinking amounts were significantly (P < 0.01) decreased from 17.0 +/- 16.5 before to 11.0 +/- 16.9 at directly, 14.2 +/- 17.8 at 12 weeks and 13.9 +/- 17.8 at 1 year after intervention. The mean AUDIT score was significantly (P < 0.01) decreased from 29.4 +/- 5.8 before to 19.1 +/- 11.0 at directly, 21.8 +/- 9.1 at 12 weeks and 23.0 +/- 9.4 at 1 year after intervention. The number of heavy drinkers and binge drinkers were significantly (P < 0.05) decreased from 32 (100%) and 32 (100%) before to 20 (62.5%) and 22 (68.8%) at directly, 23 (71.9%) and 24 (75.0%) at 12 weeks, and 22 (68.8%) and 19 (59.4%) at 1 year after intervention. CONCLUSION: It is suggested that group intervention by family physicians may be effective on the improvement of drinking behavior at 12 weeks and 1 year after the intervention in heavy drinkers.
Drinking ; Drinking Behavior ; Family Characteristics ; Follow-Up Studies ; Humans ; Male ; Physicians, Family ; Physicians, Primary Care ; Primary Health Care

PURPOSE: To determine the usefulness of transrectal ultrasound (TRUS) and to compare TRUS with intravenousurography (IVU) in the evaluation of distal ureteral calculi. MATERIALS AND METHODS: TRUS and IVU were perfomed in 24 patients with distal ureteral calculi. Using TRUS, we evaluated the presence and size of calculus, type of ureteral jet at the affected site and diameter of ureter proximal to calculus, and using IVU evaluated the presence and size of calculus, degree of ureteral obstruction, and degree of hydroureter. TRUS and IVU findings, were compared. RESULTS: In each patient, TRUS detected calculus of the distal ureter ; in only 18cases (75%),were the calculi demonstrated with IVU. In 18 cases where calculi were detected by both modalities, average calculus size was 4.5 X 3.0mm (longest and shortest dimensions) by IVU, and 6.1 X 3.7 mm by TRUS. Betwee TRUS and IVU(p<0.05) there was a statistically significant difference in the longest dimension of calculi. Color Doppler imaging revealed three patterns of ureteral jets in TRUS : normal periodic jet (7 cases) ; continuous low-levelflow (8 cases) ; and no detectable jet (9 cases). There was a positive correlation between type of ureteral jetson TRUS and between degree of obstruction on IVU (r=0.59, p<0.05). There was, however, no significant correlation between diameter of ureter proximal to calculus on TRUS and degree of hydroureter on IVU (r=0.32, p>0.05). CONCLUSION: TRUS appears to be a useful adjunctive method for the evaluation of distal ureteral calculus.
Calculi ; Humans ; Ultrasonography* ; Ureter* ; Ureteral Calculi* ; Ureteral Obstruction ; Urography*