1.Clinieal Study of the Stomach Cancer diagnosed by Endoscopy.
Ki Heon LEE ; Duk Jae SUN ; Duck LIMB
Korean Journal of Gastrointestinal Endoscopy 1983;3(1):40-45
Gastrofiberscopic findings under direct vision were analysed in 248 patients who were diagnosed as gastric cancer from Feb. 1980 to March 1983 in Department of internal Medicine, Kang Nam Sacred Heart Hospital, Hallym Medical College, Seoul, Korea. (continue...)
Endoscopy*
;
Heart
;
Humans
;
Internal Medicine
;
Korea
;
Seoul
;
Stomach Neoplasms*
;
Stomach*
2.Gram negative peritonitis in CAPD clinical manifestaions and outcomes.
Sang Koo LEE ; Dong Cheol HAN ; Min Sun PARK ; Seung Duk HWANG ; Hi Bahl LEE
Korean Journal of Nephrology 1992;11(3):279-285
No abstract available.
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
3.Flow Cytometric Analysis of DNA patterns in Carcinoma of the Uterine Cervix.
Sang Tag EUM ; Chang Soo PARK ; Sun Young KANG ; Duk Soo BAE ; Je Ho LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):342-349
OBJECTIVE: Flow cytometric deoxyribonucleic acid (DNA) content analysis has been shown to be of prognostic importance in some cancers. In this study, DNA patterns obtained by flow cytometry in patients with cervical cancer have been shown to be related to a prognostic importance in cervical carcinoma. METHODS AND MATERIALS: We retrospectively reviewed 59 cervical cancer patients who admitted to the department of obstetrics and gynecology, Samsung Medical Center firom January 1995 to May 1997. RESULTS: A total of 59 archival paraffin-embedded blocks were proc 42.4 percent were found to be DNA content aneuploid (DNA-A) and 57.6 percent DNA content diploid (DNA-D). The S-phase fraction was significantly increased with stage. The incidences of aneuploid and relative DNA index were not significantly increased with the stage(P=0.280) and age of patients(P=0.088). The results had no significant differences between the squamous cell carcinoma and adenocarcinoma, and no relationship between the groups with keratinizing cell type and nonkeratinizing type(P=0.409). The DNA ploidy patterns were not significantly correlated with metastasis to lymph node(P=0.179), tumor size(P=0.109), invasion depth(P=0.361) and recurrent group(P=0.285). High S-phase fraction had a tendency to correlate with the invasion depth(P=0,011), size(P=0.027), lymph node metastasis(P=0.039) and recurence(P=0.099) of cervical cancer. CONCLUSION: Flow cytometric DNA content analysis is being used more frequently in the management of different malignant tumors. Our study shows that DNA content analysis may not serve as an important biological indicator in determining the prognosis in cervical carcinoma, but High S-phase fraction has been connected with more aggressive tumors.
Adenocarcinoma
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Aneuploidy
;
Carcinoma, Squamous Cell
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Cervix Uteri*
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Diploidy
;
DNA*
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Female
;
Flow Cytometry
;
Gynecology
;
Humans
;
Incidence
;
Lymph Nodes
;
Neoplasm Metastasis
;
Obstetrics
;
Ploidies
;
Prognosis
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Retrospective Studies
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Uterine Cervical Neoplasms
4.Six Cases of Congenital Absence of the Vagina Managed by McIndoe Operation.
Sung Duk CHO ; Hye Sun JUN ; Chung No LEE ; In Hyun KIM ; Jae Young AHN
Korean Journal of Obstetrics and Gynecology 1997;40(1):223-228
Mullerian agenesis or dysgenesis, rare developmental anomaly presenting as primary amenorrhea, is characterized by absence of vagina and absence or rudimentary development of the uterus. Anatomic anomalies of the axial skeleton and kindney often accompany this psychologically devatating condition. There are various methods of surgical treatment for congenital absence of the vagina. The six cases reviewed in this paper were all treated with McIndoe technique. All of 6 women experienced satisfactory sexual activity and were satisfied with vaginal depth following vaginal creation using a split thickness skin graft technique. Despite the existence of several alternative methods, the McIndoe technique is a relatively simple and highly successful procedure and hence is still prefered by many surgeons.
Amenorrhea
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Female
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Humans
;
Sexual Behavior
;
Skeleton
;
Skin
;
Transplants
;
Uterus
;
Vagina*
5.Fractors Influencing the Results of Operative Treatment of Tibial Plateau Fractures
Hyoun Oh CHO ; Kyung Duk KWAK ; Sung Do CHO ; Sun Il LEE
The Journal of the Korean Orthopaedic Association 1990;25(6):1657-1664
Fractures of the tibial plateau involve a major weight-bearing joint, Thus, to achieve good joint function one must strive to achieve joint congruity, axial alignment, stability, and a satisfactory range of motion. Present operative treatment of tibial plateau fractures utilizes the principles of anatomical reduction, elevation of the plateau en masse, bone grafting of the defect in the metaphysis, stable internal fixation and early joint motion. Authors reviewed the 45 tibial plateau fractures operatively treated at Dong-Kang Hospital from Jan. 1983 to Dec. 1988 and analyzed the possible factors that could influence the results. Factors that may adversely affect the results were 1) old female. 2) Hohl Type VI, 3) delayed operation, 4) inadequate reduction, 5) no bone graft, 6) meniscectomy, 7) cruciate ligament injury, and 8) delayed exercise.
Bone Transplantation
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Female
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Humans
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Joints
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Ligaments
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Range of Motion, Articular
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Transplants
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Weight-Bearing
6.Histochemical study on the distribution of the carbohydrate in tracheal mucosa of the rat during pre- and postnatal development.
Hyung Duk OH ; Dong Kyun KIM ; Sang Hwa LEE ; Jin Jeong KIM ; Bong Sun KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):798-807
No abstract available.
Animals
;
Mucous Membrane*
;
Rats*
7.A Case of Renal Hypoplasia with Renovascular Hypertension.
Sang Doo LEE ; Jae Hee PARK ; Jae Beom LEE ; Yun Duk YOO ; Byoung Hwa LEE ; Mi Sun LEE
Journal of the Korean Pediatric Society 1995;38(11):1565-1570
No abstract available.
Hypertension, Renovascular*
8.Clinical study on aspergillosis.
Kwang Jae LEE ; Sun Ju LEE ; Je Duk OH ; Jee Sook HAHN ; Yun Woong KO ; Woo Ick YANG
Korean Journal of Infectious Diseases 1991;23(2):73-85
No abstract available.
Aspergillosis*
9.Psychogenic symptoms in patients with noncardiac chest pain.
Young Ho CHANG ; Ji Ho CHOI ; Sang Hyun LEE ; In Ho KWAK ; Sun Duk LEE
Journal of the Korean Academy of Family Medicine 1999;20(12):1784-1793
BACKGROUND: Patients with chest pain are common among outpatients. Several researches shows that chest pain patients can suffer from psychiatric illnesses such as hypochondriasis, depression, anxiety, somatization, panic disorder and so on. This study aims to examine the pschogenic symptoms in patients with noncardiac chest pain METHODS: In this study, the 98 people who have undergone treadmill test for chest pain during the three months from June 1st to September 30 of 1998 were selected, and the 98 patients were asked to respond to the prepared questionnaire and SCL-MPD(symptom check list-minor psychiatric disorders) before they underwent treadmill test. And then, they were classified into two groups. One group consisted of patients with noncardiac chest,pain, and the other group of patients with cardiac chest pain. These two groups were compared in 10 measures, and the compared results were analyzed by t-test. RESULTS: Among the 25 patients with cardiac chest pain, 15 patients were males and 10 patients (38%) were females, and among the 44 patients with noncardiac chest pain, 31 patients (70%) were males, 13 patients (30%) were females. The average age was 47 years old. The average age in patients with noncardiac chest pain was 48, and the 46 for those patients with cardiac chest pain . In the statistical analysis between the patients with cardiac chest pain and those with noncardiac chest pain, significant difference(p<0.005) was shown in the measures such as somatization, depression, phobic anxiety, obsessive-compulsive, neurasthenic, hypochondriacal, anxiety, anger-hostility, interpersonal sensitivity. CONCLUSIONS: As in the analysis the patients with noncardiac chest pain showed significant difference in the symptom check list-minor psychiatric disorder compared to those with cardiac chest pain. We conclude that primary care physician should take more interest in evaluating psychiatric symptoms in patients with noncardiac chest pain.
Anxiety
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Chest Pain*
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Depression
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Exercise Test
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Female
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Humans
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Hypochondriasis
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Male
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Middle Aged
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Outpatients
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Panic Disorder
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Physicians, Primary Care
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Thorax*
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Surveys and Questionnaires
10.Production and Expression of Gro-alpha and RANTES by Peripheral Blood Mononuclear Cells Isolated from Patients with Kawasaki Disease and Measles.
Hee Sun KIM ; Won Duk KIM ; Young Hwan LEE
Journal of Korean Medical Science 2003;18(3):381-386
We investigated whether the production and gene expression of Gro-alpha and RANTES in Kawasaki disease differ in measles. Forty-two samples from 14 patients in different clinical stages of Kawasaki disease, eight samples from 8 patients in the acute stage of measles and seven samples from 7 healthy children were collected. The present study was performed using ELISA and RT-PCR for the productions and gene expression of the chemokines. The production of Gro-alpha was markedly elevated during the acute stage of measles compared with Kawasaki disease. Moreover, the expression of Gro-alpha was increased in every case of measles, but not in Kawasaki disease. The production of RANTES was elevated in the acute stage of both diseases when compared to the healthy control. However, the plasma RANTES level did not change significantly according to the clinical stages of Kawasaki disease. A correlation between the production and gene expression of RANTES and Gro-alpha was not found in Kawasaki disease. These results suggest that Kawasaki disease differs from measles with regard to Gro-alpha production and expression, but not RANTES. Gro-alpha might play an important role in the acute stage of measles, however not in Kawasaki disease. Further studies are needed to clarify the efficacy of Gro-alpha as a marker in measles.
Biological Markers
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Chemokines/blood/*genetics
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Chemotactic Factors/blood/*genetics
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Child
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Child, Preschool
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Comparative Study
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Female
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Gene Expression/immunology
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Human
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Infant
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Intercellular Signaling Peptides and Proteins/blood/*genetics
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Leukocytes, Mononuclear/*physiology
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Male
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Measles/*immunology/physiopathology
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Mucocutaneous Lymph Node Syndrome/*immunology/physiopathology
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RANTES/blood/*genetics
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RNA, Messenger/analysis