No abstract available.
Colorectal Neoplasms*

BACKGROUND: The aging of the patient population is one of rhe most important factirs influencing health care delivery. Currently 5% of the Korean population is elderly, defined as older than 65years of age, with this group projected to increase to 13.1% by the year 2021. Cardiovascular disease is the leading cause of death and of disability in the elderly age group. mong them, coronary heart disease is the most importane. METHOD: Study population composed of 216 patients who were admittied to the hospital with first acute myocardial infarction and they were divided into two groups according to the age(older than 65 years of age vs younger). Clonical features, risk factors of coronary heart disease, in-hospital outcome and complication were compared in elderly patients and others group. Results : 1) The risk factors of coronary heart disease is similar to younger patients but pattern of chest pain is less typical than younger patients. 2) Clinical presentation of elderly patients is similar to younger patients except Killip class on admission.(1.66vs 1.91,P=0.04) 3) In-hospital mortality of elderly patients in higher than younger patients. In addition to an increased incidence of death, recurrent ischemia, stroke, AV block, ventricular arrythmia, pulmonary edema occured more frequently with advanced age. 4) Especially in the thrombolytic therapy group, in-hospital death, reinfarction and recurrent ischemia is higher than primary PTCA group in elderly patients. CONCLUSIONS: Diagnosis of acute chest pain is difficult in elderly patients and in-hospital mortality and morbidity is higher than in younger patients. Thus more accurate diagnosis and discriminative therapeutic modality is needed.
Aged ; Aging ; Arrhythmias, Cardiac ; Atrioventricular Block ; Cardiovascular Diseases ; Cause of Death ; Chest Pain ; Coronary Disease ; Delivery of Health Care ; Diagnosis ; Hospital Mortality ; Humans ; Incidence ; Ischemia ; Myocardial Infarction* ; Pulmonary Edema ; Risk Factors ; Stroke ; Thrombolytic Therapy

Duplication of the alimentary tract is an unusual congenital anomaly which may occur at any level, from the oral cavity to the rectum. Gastric duplication cyst is quite rare and most of them are presented in infancy with the sypmtoms of vomiting, abdominal pain, weight loss, gastrointestinal bleeding resulting from partial or complete obstruction. Some cases have not been diagnosed until adult when duplication cyst is not large enough to cause acute obstruction in infancy. Our case is more unusual in the aspect of its presence in adult and its nature resembles huge pancreatic pseudocyst. A 18-year man came to our hospital with complaint of epigastric pain for three days. A gastrofiberoscopy revealed a round protruding mass with smooth surface of normal mucosa at the fundus and computed tomography of the abdomen revealed the presence of 6.0 X 6.0 cm sized cystic mass between posterior wall of stomach and pancreas, and another 2.0 x 2.0 cm sized mass in ant. wall of stomach, which were regarded as mutiple pancreatic pseudocysts in perigastric region. Endoscopic retrograde cholangiopancreatography did not disclose any pancreatic ductal abnormality or communication with the cyst. Endoscopic ultrasonography showed anechoic cystic mass under 3rd layer of stomach wall, which was removed by surgical resection. Postoperative pathologic examination disclosed multiple gastric duplications.
Abdomen ; Abdominal Pain ; Adult ; Ants ; Cholangiopancreatography, Endoscopic Retrograde ; Endosonography ; Hemorrhage ; Humans ; Mouth ; Mucous Membrane ; Pancreas ; Pancreatic Ducts ; Pancreatic Pseudocyst* ; Rectum ; Stomach ; Vomiting ; Weight Loss

Carcinoma of the gallbladder is relatively rare malignancy usually found in an elderly, predominantly female population. Histologically, adenocarcinoma predominate, with only 10% to 15% being of other varieties(small cell carcinoma and others). Small cell carcinoma of the gallbladder is a rare lesion and predominantly a disease of older women with clinical history of stones. These tumors show an aggressive clinical course and death usually occurs with in a few months of the diagnosis. The diagnosis of small cell carcinoma should be based on cell morphology, histologic pattern and immunohistochemical study. Correct diagnosis is important not only because these tumors give rise to endocrine syndromes, but also because the chemotherapeutic approach to small cell carcinoma differs from that for adenocarcinoma.
Adenocarcinoma ; Aged ; Carcinoma, Small Cell* ; Diagnosis ; Female ; Gallbladder* ; Humans

The extension of infiltrating gastric cancer through the gastrocolic ligament into the transverse colon appears to be relatively common, but metastases from the ileocecal valve to the sigmoid colon are rare conditions and have been reported in only a few cases. Although direct invasion of tumor cells into the transverse colon and peritoneal dis-semination through the entire colon was a main cause of colon metastasis of gastric cancer, variable other causes were divided, by method of invasion to other organ. There are a few description for endoscopic finding of metastatic colon cancer. A 45-year-old man was admitted to our hospital because of epigastric discomfort and pain for 3 months ago. He was confirmed to have diffuse infiltrating adenocarcinoma (Borrman type IV) by gastro-duodenoscopy, endoscopic ultrasonography, and diagnosed as the colonic invasion by the colonoscopy and biopsy. We report a case of advanced gastric cancer with colon metastasis and review its pathogenetics and endoscopic characteristics from relevant literature.
Adenocarcinoma ; Biopsy ; Colon* ; Colon, Sigmoid ; Colon, Transverse ; Colonic Neoplasms ; Colonoscopy ; Endosonography ; Humans ; Ileocecal Valve ; Ligaments ; Middle Aged ; Neoplasm Metastasis* ; Stomach Neoplasms*

Gastrointestinal stromal tumor (GIST) were previously known as smooth muscle tumor like leiomyoma or leiomyosarcoma. Most of them were histologically spindle cell tumors, usually of mesenchymal origin. Stromal tumors account for about 1% to 2% of gastric malignant tumor, and the most important characteristics is their indolent, slow-growing nature, rendering most common definitions of malignancy invalid and inapplicable. The tumors are generally found deep within the stroma and submucosa, and only about half have an intragastric component, detectable by radiography, endoscopy or endoscopic ultra-sonography (EUS). Especially EUS is a valuable technique for diagnosing GIST. We experienced a 35-year-old female patient who complained right upper quadrant pain. She was diagnosed as subserosal stromal tumor by gastrofiberscopy, EUS, abdominal CT and operation. We report a case of gastric subserosal stromal tumor with a review of relevant literatures.
Adult ; Endoscopy ; Female ; Gastrointestinal Stromal Tumors ; Humans ; Leiomyoma ; Leiomyosarcoma ; Radiography ; Smooth Muscle Tumor ; Stomach* ; Tomography, X-Ray Computed

Menetrier's disease is a rare, characterized by the presence of large rugal folds involving part or all of the stomach. Patients with hypertrophic gastropathy often have distressing abdominal symptoms, weight loss, and edema due to gastric protem loss. A 64 year old male patient was admitted with the chief complaint of epigastric discomfort. Endoscopic, radiologic and histologic examination, revealed characteristic findings of Menetrier's disease. A case of Menetrier's disease is reported with a brief review of literature.
Edema ; Gastritis, Hypertrophic* ; Humans ; Male ; Middle Aged ; Stomach ; Weight Loss

In this study, the effects of corn peptide consumption on plasma lipid profiles were investigated in high cholesterol dietfed rats. Male Sprague-Dawley rats (n = 21) were fed with corn peptide-free (control) diet, diets containing 2% or 5% corn peptide for 5 weeks. Hypercholesterolemia was induced by adding 1% cholesterol and 0.5% cholic acid to all diets. No difference was found in food intake and body weight gain among groups. The corn peptide treated groups showed significant improvement in the plasma level of HDL-cholesterol (p < 0.05) compared to the control group, while the plasma total cholesterol and LDL-cholesterol were not affected. 5% corn peptide supplemented diet reduced plasma level of triglycerides (p < 0.05). The atherogenic index was decreased in the corn peptide treated groups. These results suggest that consumption of corn peptide may lead to an amelioration of metabolic syndrome as well as a reduction of cardiovascular disease and hyperlipidemia through increasing the level of HDL-cholesterol, and decreasing the level of triglycerides in plasma.
Animals ; Body Weight ; Cardiovascular Diseases ; Cholesterol ; Cholic Acid ; Diet ; Eating ; Humans ; Hypercholesterolemia ; Hyperlipidemias ; Male ; Plasma* ; Rats* ; Rats, Sprague-Dawley ; Triglycerides ; Zea mays*

Stenosing papillitis is a descriptive term for an anatomic deformity of the Ampulla of Vater due to chronic inflammation and fibrosis, which is characterized by narrowing of the lower end of the bile and pancreatic duct, and by clinical symptoms resembling pancreticobiliary disease. Duodenoscopic finding of "stenosing papillitis" usually shows edema, erythema, and laceration on Ampulla of Vater, but endoscopic finding such as polypoid mass is rare. We recently experienced one case of polypoid stenosing papillitis and report with a review of relevant literatures A 54-year-old man was admitted to our hospital because of chronic right upper abdominal pain for 2 years. Duodenoscopy re-vealed a polypoid mass with erythemaous color change on Ampulla of Vater, which was endoscopically resected by using a polypectomy snare, and pathologic examination showed chronic inflammation and fibrosis.
Abdominal Pain ; Ampulla of Vater* ; Bile ; Congenital Abnormalities ; Duodenoscopy ; Edema ; Erythema ; Fibrosis ; Humans ; Inflammation ; Lacerations ; Middle Aged ; Pancreatic Ducts ; Papilledema* ; SNARE Proteins

Malignant melanomas are common metastatic lesions in the gastrointestinal tract. There are some descriptions for endoscopic findings but few reports on the endoscopic ultrasonographic findings of metastatic malignant melanomas in the stomach. A 67-year-old woman was admitted due to indigestion persisting for 1 month. She had a 3x4 cm sized black pigmented skin lesion on her left foot. An abdominal ultrasonography and CT scan revealed multiple variable sized round lesions in the liver, suggesting metastatic lesions. An endoscopy revealed multiple, elevated lesions with central ulcerations and a star shaped black pigmentation around the ulcer mound on the antrum of the stomach, as well as huge ulcers with black pigmented bases on the upper body. An endoscopic ultrasonography determined that the depths of the elevated lesions on the antrum were 1imited to the mucosal layer and that huge ulcers on the upper body were invading the serosa simultaneously. The skin lesion was diagnosed as a malignant melanoma and the stomach lesion were also confirmed to be metastatic malignant melanomas. The case of malignant melanomas that metastased to the stomach and had unusual endoscopic ultrasonographic findings is herein reported.
Aged ; Dyspepsia ; Endoscopy ; Endosonography ; Female ; Foot ; Gastrointestinal Tract ; Humans ; Liver ; Melanoma* ; Neoplasm Metastasis ; Pigmentation ; Serous Membrane ; Skin ; Stomach* ; Tomography, X-Ray Computed ; Ulcer ; Ultrasonography