No abstract available.
Glaucoma* ; Manometry* ; Mass Screening*

The authors experienced a case of pulmonary alveolar proteinosis. A 58-year-old woman presented with 6 months duration of cough sputum and multiple patch mottled densities in both lung fields. Major histologic finding was filling of the alveoli by Periodic-Acid-Schiff-positive proteinaceous material with maintenance of normal alveolar architecture. Osseous metaplasia was seen in the alveolar space, focally. Ultrastructural study revealed numerous lamellar bodies in alveolar spaces. The immunohistochemical study using antibody to surfactant apoprotein revealed positive reaction in proteinaceous material.
Female ; Humans

PURPOSE: The purpose of this study was to identify effects of an obesity control program including rhythmical dance exercise, on body composition, knowledge about obesity, life habits and self-esteem among obese elementary school children. This program included obesity related health education and counseling based on behavior modification once a week, 1 hour-rhythmical dance class once a week and 40-minute jump rope classes twice a week for 8 weeks. METHOD: There were 29 students with obesity in the experimental and 28 in the control group. Participated was voluntary. The data were collected from April 16 to July 6 2007. chi-square-test, Fisher's exact test, paired t-test and t-test were used to analyze the data. RESULTS: Students in the experimental group showed significantly lower fat mass (t=-2.16, p=.036) and percent body fat (t=-2.93, p=.005) and significantly higher muscle mass (t=2.05, p=.045) and lean body mass (t=2.71, p=.009) than those in the control group. Knowledge of obesity increased significantly and eating habits changed significantly. But difference in exercise habits and self-esteem were not significant. CONCLUSION: This study provides evidence that an 8 week-obesity control program including rhythmical dance exercise is effective in decreasing body fat, increasing muscle mass and increasing knowledge of obesity in children who are obese.
Adipose Tissue ; Behavior Therapy ; Body Composition ; Child ; Counseling ; Eating ; Health Education ; Humans ; Muscles ; Obesity

Purpose: This study is aimed to identify the influence of nurses’ anger management ability, resilience, and self-compassion on their nursing work performance. Methods: The study included 220 nurses from 5 hospitals in Gyeonggi-do who consented to participate. Data were collected from July 20 to August 20, 2019. It was conducted that Descriptive analysis, t-test, Pearson's correlation coefficient, multiple regression, ANOVA, and Scheffétest using SPSS 25.0 program.Result: The nurses' work performance showed positive correlations with anger management ability, resilience, and self-compassion. Factors affecting the work performance of nurses were resilience (β=.46, p<.001), total work experience (β=.22, p=.014), current department work experience (β=.17, p=.009), anger management ability (β=.13, p=.026), and the overall explanatory power of these factors was 54.6%. Conclusion This study showed that resilience, total work experience, current work experience, and anger management ability were important variables that influence the work performance of nurses. To enhance the nursing performance of clinical nurses, it is necessary to develop and implement training programs that enhance resilience and educational programs that help them manage their anger management ability.

Purpose: This study is aimed to identify the influence of nurses’ anger management ability, resilience, and self-compassion on their nursing work performance. Methods: The study included 220 nurses from 5 hospitals in Gyeonggi-do who consented to participate. Data were collected from July 20 to August 20, 2019. It was conducted that Descriptive analysis, t-test, Pearson's correlation coefficient, multiple regression, ANOVA, and Scheffétest using SPSS 25.0 program.Result: The nurses' work performance showed positive correlations with anger management ability, resilience, and self-compassion. Factors affecting the work performance of nurses were resilience (β=.46, p<.001), total work experience (β=.22, p=.014), current department work experience (β=.17, p=.009), anger management ability (β=.13, p=.026), and the overall explanatory power of these factors was 54.6%. Conclusion This study showed that resilience, total work experience, current work experience, and anger management ability were important variables that influence the work performance of nurses. To enhance the nursing performance of clinical nurses, it is necessary to develop and implement training programs that enhance resilience and educational programs that help them manage their anger management ability.

The recent prevalence of syphilis has known to be increased progressively throughout the world, since middle of 1950. In Korea, current trend of increased syphilic infection has became a major public health problem. The authors selected sero-positive patients, among the outpaients of department of dermatology, urology, OB & GY, and physical examination, and performed statistical analysis of this sero-positive patients. Results are as following; 1) Of the 2,007 patients taken physical examination, 30 patient(1.49%) were reactive to VDRL. 2) 0.71% of the total out patients of the dermatologic dcpartment were sero-positive. Annual ratio of the syphilitic patient were increased progressively. 3) Ratio of the syphilitic patients to the total outpatients of OB & GY department was 0.55% and somewhat increased since 1976. 4) In the age distribution, the third decade shared 51.8% of the total sero-positive patients 5) In the sexual ratio. male:female=l: l. 62 in the total sero-positive patients. (male:female=l: 1.06 in the dermatologic department.) 6) In the stage distribution, latent syphilis patients were 59.14% of the total syphilitic patients.
Age Distribution ; Dermatology ; Female ; Humans ; Korea ; Outpatients ; Physical Examination ; Prevalence ; Public Health ; Syphilis ; Syphilis, Latent ; Urology

Magnetic resonance images frequently demonstrate asymmetrical mucosal volume in the nasal area of asymptomatic patients. To further evaluate this phenomenon, sequential MR examinations of the nasal cavity and paranasal sinuses were performed three to four times during a 3 to 8 hours period in ten normal volunteers. The study demonstrated that the mucosal volume changes alternated from side to side during this period in eight volunteers. Changes were also observed within the ethmoid sinuses, nasal septum and nasolacrimal ducts. Awareness of MR findings of nasal cycle may reduce the likehood of inflammatory disease being confused with normal physiologic changes, and also may provide another method in the study of this physiologic phenomenon.
Ethmoid Sinus ; Healthy Volunteers ; Humans ; Methods ; Nasal Cavity ; Nasal Septum ; Nasolacrimal Duct ; Paranasal Sinuses ; Volunteers

PURPOSE: There is no standard targeted therapy for the treatment of triple-negative breast cancer (TNBC). Therefore, its management heavily depends on adjuvant chemotherapy. Using core needle biopsy, this study evaluated the histological factors of TNBC predicting the response to chemotherapy. METHODS: One hundred forty-three TNBC patients who received single-regimen neoadjuvant chemotherapy (NAC) with the combination of doxorubicin, cyclophosphamide, and docetaxel were enrolled. The core needle biopsy specimens acquired before NAC were used to analyze the clinicopathologic variables and overall performance of the predictive model for therapeutic response. RESULTS: Independent predictors of pathologic complete response after NAC were found to be higher number of tumor infiltrating lymphocytes (p=0.007), absence of clear cytoplasm (p=0.008), low necrosis (p=0.018), and high histologic grade (p=0.039). In the receiver operating characteristics curve analysis, the area under curve for the combination of these four variables was 0.777. CONCLUSION: The present study demonstrated that a predictive model using the above four variables can predict therapeutic response to single-regimen NAC with the combination of doxorubicin, cyclophosphamide, and docetaxel in TNBC. Therefore, adding these morphologic variables to clinical and genomic signatures might enhance the ability to predict the therapeutic response to NAC in TNBC.
Area Under Curve ; Biopsy, Large-Core Needle ; Chemotherapy, Adjuvant ; Cyclophosphamide ; Cytoplasm ; Doxorubicin ; Drug Therapy* ; Humans ; Lymphocytes, Tumor-Infiltrating ; Necrosis ; Neoadjuvant Therapy ; ROC Curve ; Treatment Outcome ; Triple Negative Breast Neoplasms*

BACKGROUND AND AIMS: To further understand the relationship between the cagA gene and gastric cancer, the positive rates of the cagA gene in cancer and non-cancer tissues were investigated separately in patients with gastric cancer. METHODS: The cagA gene was detected by PCR and the ureC gene was analyzed as a positive control for the presence of Helicobacter pylori. Each of two endoscopic biopsies were obtained from cancer and non-cancer tissues of 41 patients with gastric cancer. RESULTS: 1) The positive rate of the cagA gene in cancer tissues was 29.3% (12/41), which was significantly lower than that in non-cancer tissues (63.4%). 2) Twelve (29.3%) out of 41 were positive for the cagA gene in both cancer and non-cancer tissues, 14 were positive in only non-cancer tissues, none were positive in only cancer tissues, and 15 (36.6%) were negative in both sites. 3) The ureC gene was negative in cancer tissue in 12 (85.7%) among 14 cases who were cagA gene negative in the cancer tissue but positive in the non-cancer tissue. 4) There was no difference in the positive rate of the cagA gene according to age, stage, site, and pathologic cell type. CONCLUSIONS: These findings indicate that the positive rate of the cagA gene in cancer tissue was lower than that in non-cancer tissues and this might be related to a low infection rate of H. pylori in cancer tissue rather than the presence of cagA negative H. pylori in cancer tissues.
Biopsy ; Helicobacter pylori* ; Helicobacter* ; Humans ; Polymerase Chain Reaction ; Stomach Neoplasms*

BACKGROUND: Ischemic heart disease and cerebrovascular disease are the main causes of death and platelets are responsible for the formation of arterial thrombi. Platelet membrane glycoproteins (GP) associated with coagulation pathway are GPIb/V/IX, GPIa/IIa, and GPIIb/IIIa. We evaluated genotype and allele frequencies of seven platelet glycoprotein genes associated with arterial thrombosis. METHODS: Genomic DNA was isolated from peripheral blood of 300 unrelated Korean and single nucleotide polymorphism of platelet glycoproteins was analyzed. PCR with sequence specific primers was used to investigate GPIa C807T and GPIbalpha VNTR polymorphism. PCR-RFLP (restriction fragment length polymorphism) was used to investigate GPIa G1648A and C2531T, GPIbalpha C524T and T-5C, and GPIIIa T1565C polymorphism. RESULTS: The allele frequencies of GPIa C807T were 807C 0.733, 807T 0.267; GPIa 1648G 0.975, 1648A 0.025; GPIa C2531T, 2531C 1.000, 2531T 0.000; GPIbalpha C524T, 524C 0.927, 524T 0.073; GPIbalpha VNTR, A 0.017, B 0.015, C 0.558, D 0.410; GPIbalpha T-5C, -5T 0.726, -5C 0.274; GPIIIa T1565C, 1565T 0.995, 1565C 0.005. CONCLUSION: The genotype and allele frequencies of GPIa G1648A, GPIbalpha C524T, and GPIIIa T1565C were similar to established data. GPIa 807T and -5T allele of Kozak polymorphism showed low frequency compared with other ethnic group. Allele frequencies of GPIbalpha VNTR A and B alleles were very alike (0.017 vs 0.015). In this study, we firstly evaluated the genotype and allele frequencies of GPIa C2531T and GPIbalpha VNTR, T-5C polymorphisms in Korean population. This study will serve as a basic data for the study of platelet glycoproteins associated with arterial thrombosis in Korean.
Alleles* ; Blood Platelets* ; Cause of Death ; DNA ; Ethnic Groups ; Gene Frequency* ; Genotype* ; Glycoproteins* ; Humans ; Integrin alpha2 ; Integrin beta3 ; Myocardial Ischemia ; Platelet Membrane Glycoproteins ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; Thrombosis*