No absteact available.
Dermatitis, Atopic* ; Diagnosis*

No abstract available.
Adolescent* ; Humans ; Intention* ; Smoke* ; Smoking Cessation* ; Smoking*

DNA flow cytometric analysis was performed on paraffin-embedded tissue from 10 cases of squamous cell eareinoma (SCC) and 10 cases of basal cell carcinoma(BCC). These results were applicable to do a better prognosis in BCC than SCC. In 10 cases of SCC, the DNA index was 1.34 and aneuploidy was identified in 9. In 10 cases of BCC, the DNA index was 1.30 and aneuploidy was identified in 6.
Aneuploidy ; Carcinoma, Basal Cell* ; Carcinoma, Squamous Cell* ; DNA* ; Flow Cytometry* ; Prognosis ; Skin*

No abstract available.
Colitis, Ulcerative* ; Sweet Syndrome* ; Ulcer*

BACKGROUND: Calcinosis cutis may occur when connective tissue is abnormal (dystrophic), or where calcium or phosphate levels in the blood are high(metastatic); alternatively, there may be no obvious underlying cause(idiopathic). The exact incidence of calcinosis cutis in dermatologic patients is not well-kniown and the pathomechanism of it remains to be elucidated. OBJECTIVE: This study was performed to analyze the incidence, clinical and histopathological features of calcinosis cutis. METHODS: We studied 72 patients with calcinosis cutis who visited our department between January 1985 and December 1996. The patients were classified into 3 types (dystrophic, metastatic, and idiopathic) and were analyzed clinically and histopathologically. Results : The results were summerized as follows; 1. There were 60 cases(83.3%) and 12 cases(16.7%) of the dystrophic and idiopathic types, respectively but the metastatic type was not observed. The frequency of dystrophic calcification in individual disorders was 88.2% in pseudoxanthoma elasticum, 66.7% in trichilemmal cyst and dermatomyositis, and 64.6% in pilomatrichoma. 2. In the idiopathic type, it was common in females aged over 50 years and the mean duration of lesions was 2.8+/-2.0 years. The predilection site was the flank(5 cases) and most of the lesions(7 cases) showed skin-colored nodules 3. Histopathologically, calcified material of the idiopathic type was located predominently in the dermis(10 cases) and was present as large masses surrounded by a foreign body reaction. 4. In the dystrophic type, calcified deposits were noted predominently within the shadow cells of pilomatricoma, in the degenerated elastic fibers of pseudoxanthoma elasticum, and in the keratinized area of basal cell carcinoma, squamous cell carcinoma, trichilemmal cyst, and epidermal cyst. Foreign body reactions with giant cells and mononuclear cell infiltrations were often found around large deposits of calcium. Conclusion : The incidence of calcinosis cutis in dermatologic patients is relatively low, but a variety of disorders can be associated with cutaneous calcification. Therefore, dermatologists should be familiar with the different forms of cutaneous calcification and the dermatoses that manifest them.
Calcinosis* ; Calcium ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Connective Tissue ; Dermatomyositis ; Elastic Tissue ; Epidermal Cyst ; Female ; Foreign Bodies ; Foreign-Body Reaction ; Giant Cells ; Humans ; Incidence ; Pilomatrixoma ; Pseudoxanthoma Elasticum ; Skin Diseases

Plasmid vectors with either RSV or CMV promoter are frequently used for DNA- mediated immunization due to the availability in commercial. Consequently, influence of the vector constituents, such as promoter, enhancer and transcription termination signal etc. on vaccination efficiency is not studied extensively. As an initial attempt to develop an efficient vector system for DNA-rnediated immunization, influence of promoter for antigen gene expression on vaccination efficiency has been analyzed. Initially, plasmids with either B-actin or muscle creatine kinase (MCK) promoter were constructed from the plasmid with prototype CMV promoter. In addition, ovalbumin (OVA) antigen gene has been cloned into each vectors to generate the plasmid vectors with different promoters for induction of the anti-OVA immune responses. Antigen protein expression in antigen gene transfected mouse muscle myoblast cells showed that the level from MCK promoter containing plasmid was slightly higher than those from either CMV or B-actin promoter containing plasmids. Also, the same plasmid turned out to be slightly more efficient than other plasmids in antibody imrnune response induction in vivo, when they were applied both through intramuscularly and intradermally. These results suggest that the commonly used CMV promoter containing plasmid vector could be further modified to develop an efficient vector for DNA-mediated immunization.
Animals ; Clone Cells ; Creatine Kinase, MM Form ; Gene Expression ; Immunization ; Mice ; Myoblasts ; Ovalbumin ; Plasmids* ; Vaccination*

PURPOSE: The purpose of this study was to analyze the differences in terms of services and cost between CVA without typical diseases (Group I), and CVA with typical diseases (Group II), in their Hospital-based home health care. METHOD: The subjects of this study were 308 CVA patients who used home care nursing during the second phase demonstration project of their hospital-based home health care. Results: The results of the study was as follows 1. Group II had more home visit (15.3/12.7) (p>0.05), and cases of death when home care (16.8/11.4) (p<0.05). 2. Group II needed more services than Group I such as bladder irrigation, skin care, bed sore care, glycerin enema, finger enema, lung care, urine sugar test, monitoring and surveillance of fluid infusion and R.O.M exercise (p<0.05). 3. The variables that showed statistical significance in the regression analysis were family style, OPD visit, level of consciousness, patient's state on termination of home care, and some extend of home health care services (R2=0.373, 0.205). CONCLUSION: Home nursing care needs to be planned by severity in Hospital-based home health care for CVA patients.
Consciousness ; Delivery of Health Care* ; Enema ; Fingers ; Glycerol ; Home Care Services ; Home Nursing ; House Calls ; Humans ; Lung ; Nursing ; Pressure Ulcer ; Skin Care ; Urinary Bladder

PURPOSE: The purpose of this study was to examine the relationship between spiritual well-being, depression, and health status of elderly women in a community for providing the basic data necessary to improve the practice of nursing. METHOD: The participants were 295 elderly women, over 65 years old in Gwangju and Kyongbuk province, Korea. The data were collected between April 15th and June 15, 2003 using a structured questionnaire and were analyzed using SPSS Win 8.0. RESULT: Factors such as religious belief (p< .001), type of religion (p< .001), participation of worship (p< .001), significance of religion (p< .001), education (p=.001), spouse (p=.015), financial supporter (p=.001), and living satisfaction (p< .001) showed a statistically significant relation with spiritual well-being. There was a negative correlation between spiritual well-being and depression (r=-0.32, p< .001), and between health status and depression (r=-0.50, p< .001). However, there was a positive correlation between spiritual well-being and health status (r=0.32, p< .001). CONCLUSION: In order to promote spiritual well-being in elderly women, it is necessary to develop a nursing intervention program classified by the type of religions, followed by studies on the results of proven intervention programs.
Aged* ; Depression* ; Education ; Female ; Financial Support ; Gwangju ; Gyeongsangbuk-do ; Humans ; Korea ; Nursing ; Surveys and Questionnaires ; Religion ; Spouses

PURPOSE: The purpose of this study was to evaluate the factors which are related to the maternal role performance of first-time mother to improve the health of infant. Specifically a basic hypothetical model was developed based on the previous study about a model of social networks. METHOD: The survey was done from January to February in 2001. Total 257 mothers who have four to twelve month old first-time baby was interviewed in five community health center around country(Seoul, Choung-ju, Asan, Cheon-an, Jeju). Finally 247 data was analyzed. Data analysis was done with LISREL 8.20 program for covariance structural analysis. RESULTS: Compared to the hypothetical model, the revised model has become parsimonious and had a better fit to the data(X(2)=167.55(p=.00), X(2)/df=1.48, GFI=0.97, AGFI=0.95, RMR=0.049, NFI=0.98, NNFI=0.99, CN= 222.53). All predictive variables of the maternal role of first-time mother explained 30% of total variance in model. Social network structural characteristics and social network interactional characteristics had significant effect on the emotional support and the information support. And social network interactional characteristics had significant effect on the service support, material support and social companionship support. The service support and social companionship support had significant effect on the maternal role strain. The emotional support and the social companionship support had significant effect on the maternal role of first-time mother. CONCLUSION: As the conclusion of this study, there is in need of the developing the programmes focussed on the social network for the first-time mother.
Chungcheongnam-do ; Community Health Centers ; Humans ; Infant ; Mothers* ; Statistics as Topic

Adolescent ; Adult ; Aged ; Cystitis ; etiology ; prevention & control ; Female ; Hematopoietic Stem Cell Transplantation ; adverse effects ; Hemorrhage ; etiology ; prevention & control ; Humans ; Injections, Intravenous ; Male ; Mesna ; administration & dosage ; therapeutic use ; Middle Aged ; Transplantation Conditioning ; methods ; Young Adult