Molar-incisor malformation (MIM) is a newly reported dental anomaly with molar root deformity and incisor crown defects. MIM-affected teeth may cause severe pain with no apparent tooth caries. Since the affected molars clinically appear normal, radiographs are recommended for accurate diagnosis on the first visit. Since MIM-affected patients are in mixed dentition, timely and appropriate interventions are needed to avoid unnecessary pain and complicated clinical issues. This report was written to describe two patients who had MIM in early mixed dentition and report their 2-year follow-ups.

The purpose of this study was to compare surface hardness between titanium-nitride coated crowns (TiNCs) and stainless steel crowns (SSCs), and to evaluate the corrosion resistance and color sustainability of TiNCs.
Ten TiNCs and 10 SSCs were used for the hardness test. Measurement was performed 30 times for each type of crowns, and the mean values were compared. Metallic raw material plates (before being processed into crowns) of TiNCs and SSCs were prepared for the corrosion resistance test. The total amounts of metal ion releases in the test solution were detected by inductively coupled plasma-optical emission spectrometry. Five TiNCs were subjected to the color sustainability test by applying repetitive brushing forces.
The mean hardness values of TiNC group and SSC group were 395.53 ± 105.90 Hv and 278.70 ± 31.45 Hv respectively. Hardness of TiNCs were significantly higher than that of SSCs. The total amounts of metal ion releases from the materials of TiNCs and SSCs satisfied the criterion in International Organization for Standardization 22674. The results mean that TiNCs and SSCs were not harmful in an acidic environment. The golden coating was stable against the repetitive physical stimulations for a given period time.

Iron deficiency is the most common nutritional deficiency in children and adolescents. Pediatric collagenous gastritis (CG) is a rare gastrointestinal disorder. Abdominal pain associated with iron deficiency anemia (IDA) is a common clinical symptom.We present three cases of pediatric CG diagnosed during the treatment of recurrent IDA. During esophagogastroduodenoscopy (EGD), nodularity of the gastric corpus was observed, which is a characteristic finding in pediatric patients with CG.Although pediatric CG could not be diagnosed by general EGD biopsy and pathological examination, it was diagnosed after suspecting pediatric CG and performing appropriate diagnostic tests. We recommend EGD for pediatric patients with recurrent IDA, especially for those with gastrointestinal symptoms. Moreover, when performing EGD, conducting appropriate examinations for pediatric CG is necessary.

Purpose: To assess the prevalence of dry eye disease (DED) and ocular surface conditions in patients before cataract surgery at a tertiary hospital in South Korea. Methods: This retrospective study included 96 eyes of 96 patients scheduled for cataract surgery from March to June 2023. The primary metrics of DED, including the Symptom Assessment in Dry Eye (SANDE) score, tear film breakup time (TBUT), tear secretion (Schirmer test), and ocular staining score (OSS, Oxford grading), were investigated. The proportion of patients with DED was determined according to the Asia Dry Eye Society (ADES) and revised Korean DED guidelines. Results: The patients’ mean age was 65.9 ± 8.3 years, with a mean SANDE score of 55.6 ± 30.5. The mean TBUT, OSS, and tear secretion were 3.5 ± 1.2 seconds, 1.3 ± 0.8 points, and 7.0 ± 5.4 mm, respectively. Among the patients, 85.4% exhibited a SANDE score of 20 or higher, 99% had a TBUT of < 7 seconds, and 88.4% exhibited one or more points on the OSS. According to the ADES and revised South Korean guidelines, 79.2% and 86.5% of patients were diagnosed with DED, respectively. Furthermore, all 96 patients exhibited at least one abnormal dry eye sign, regardless of symptoms. Conclusions The prevalence of DED in patients before cataract surgery was > 80%, with all patients exhibiting at least one ocular surface abnormality. Therefore, identifying and managing ocular surface abnormalities before cataract surgery is imperative.

Ramucirumab is a vascular endothelial growth factor (VEGF) receptor-2 inhibiting monoclonal antibody for the treatment of gastric cancer, non-small cell lung cancer, colorectal cancer, and hepatocellular carcinoma. Some VEGF inhibitors are known to increase the risk of ischemic stroke; however, their association with ramucirumab remains controversial. To the best of our knowledge, only two cases of ischemic stroke following ramucirumab treatment have been reported worldwide. We herein present the first case of acute cerebral infarction secondary to ramucirumab in Korea.

Purpose: To assess the prevalence of dry eye disease (DED) and ocular surface conditions in patients before cataract surgery at a tertiary hospital in South Korea. Methods: This retrospective study included 96 eyes of 96 patients scheduled for cataract surgery from March to June 2023. The primary metrics of DED, including the Symptom Assessment in Dry Eye (SANDE) score, tear film breakup time (TBUT), tear secretion (Schirmer test), and ocular staining score (OSS, Oxford grading), were investigated. The proportion of patients with DED was determined according to the Asia Dry Eye Society (ADES) and revised Korean DED guidelines. Results: The patients’ mean age was 65.9 ± 8.3 years, with a mean SANDE score of 55.6 ± 30.5. The mean TBUT, OSS, and tear secretion were 3.5 ± 1.2 seconds, 1.3 ± 0.8 points, and 7.0 ± 5.4 mm, respectively. Among the patients, 85.4% exhibited a SANDE score of 20 or higher, 99% had a TBUT of < 7 seconds, and 88.4% exhibited one or more points on the OSS. According to the ADES and revised South Korean guidelines, 79.2% and 86.5% of patients were diagnosed with DED, respectively. Furthermore, all 96 patients exhibited at least one abnormal dry eye sign, regardless of symptoms. Conclusions The prevalence of DED in patients before cataract surgery was > 80%, with all patients exhibiting at least one ocular surface abnormality. Therefore, identifying and managing ocular surface abnormalities before cataract surgery is imperative.

Ramucirumab is a vascular endothelial growth factor (VEGF) receptor-2 inhibiting monoclonal antibody for the treatment of gastric cancer, non-small cell lung cancer, colorectal cancer, and hepatocellular carcinoma. Some VEGF inhibitors are known to increase the risk of ischemic stroke; however, their association with ramucirumab remains controversial. To the best of our knowledge, only two cases of ischemic stroke following ramucirumab treatment have been reported worldwide. We herein present the first case of acute cerebral infarction secondary to ramucirumab in Korea.

Purpose: To assess the prevalence of dry eye disease (DED) and ocular surface conditions in patients before cataract surgery at a tertiary hospital in South Korea. Methods: This retrospective study included 96 eyes of 96 patients scheduled for cataract surgery from March to June 2023. The primary metrics of DED, including the Symptom Assessment in Dry Eye (SANDE) score, tear film breakup time (TBUT), tear secretion (Schirmer test), and ocular staining score (OSS, Oxford grading), were investigated. The proportion of patients with DED was determined according to the Asia Dry Eye Society (ADES) and revised Korean DED guidelines. Results: The patients’ mean age was 65.9 ± 8.3 years, with a mean SANDE score of 55.6 ± 30.5. The mean TBUT, OSS, and tear secretion were 3.5 ± 1.2 seconds, 1.3 ± 0.8 points, and 7.0 ± 5.4 mm, respectively. Among the patients, 85.4% exhibited a SANDE score of 20 or higher, 99% had a TBUT of < 7 seconds, and 88.4% exhibited one or more points on the OSS. According to the ADES and revised South Korean guidelines, 79.2% and 86.5% of patients were diagnosed with DED, respectively. Furthermore, all 96 patients exhibited at least one abnormal dry eye sign, regardless of symptoms. Conclusions The prevalence of DED in patients before cataract surgery was > 80%, with all patients exhibiting at least one ocular surface abnormality. Therefore, identifying and managing ocular surface abnormalities before cataract surgery is imperative.

Purpose: Proteins are major components of the body and essential nutrients for proper growth and development. However, studies on protein intake in children and adolescents are insufficient. A few previous studies have reported the relationship with growth indicators, but results vary depending on the source of protein. Therefore, the current study investigates the relationship between protein intake and overweight and obesity among children and adolescents in Korea. Methods: Based on the 2014–2019 Korea National Health and Nutrition Examination Survey, 5,567 children and adolescents aged 6–18 years, who participated in a 24-hour dietary recall with information on height and weight, were included in this study. Protein intake was estimated as percentage of total energy (% of energy) and was classified into animal and plant protein according to the food source. Overweight and obesity were defined using the 2017 pediatric and adolescent growth chart. Results: Total protein intake of the subjects was estimated as 14.5% of total energy (animal protein 8.3% and plant protein 6.3%). The group with the highest total protein intake had a higher odds ratio (OR) of overweight/obesity than those with the least protein intake (OR, 1.36, 95% confidence interval (CI), 1.10-1.67, p for trend = 0.003). When classified by food source, the group with the highest animal protein intake had a significantly higher OR of overweight/obesity than subjects with the lowest intake (OR, 1.30, 95% CI, 1.05-1.61, p for trend = 0.016). However, plant protein was not significantly associated with overweight/obesity. Conclusions These findings suggest that a high intake of animal protein in children and adolescents increases the risk of being overweight and obese. In order to develop normal growth and prevent obesity in the future, it is necessary to determine an appropriate protein intake level through nutrition education programs and prospective studies on balanced protein intake.