2.Drug Eluting Stents in Infrapopliteal Arterial Disease: A Pilot Safety Study in an Asian Population.
Karthikeyan DAMODHARAN ; Ankur PATEL ; Farah Gillan IRANI ; Mark Christiaan BURGMANS ; Apoorva GOGNA ; Kiang Hiong TAY ; Richard Hg LO ; Chow Wei TOO ; Sum LEONG ; Nanda VENKATANARASIMHA ; Shaun CHAN ; Hlaing Hlaing WIN ; Chandramohan SIVANATHAN ; Bien Soo TAN
Annals of the Academy of Medicine, Singapore 2017;46(4):155-159
3.Perfluorobutane contrast-enhanced ultrasonography: a new standard for ultrasonography-guided thermal ablation of sonographically occult liver tumours?
Haiyuan SHI ; Yi-Ting ONG ; Apoorva GOGNA ; Nanda VENKATANARASIMHA ; Sarat Kumar SANAMANDRA ; Sum LEONG ; Farah Gillan IRANI ; Richard Hoau Gong LO ; Chow Wei TOO
Singapore medical journal 2021;62(10):546-553
INTRODUCTION:
Image-guided thermal ablation, preferably with ultrasonography (US), is increasingly used for treatment of small liver tumours. Perfluorobutane-contrast-enhanced US (pCEUS) is a promising tool that may allow for targeting of tumours that are otherwise imperceptible on greyscale US. Although pCEUS has been reported to be effective, the literature has been limited outside of Japan and South Korea. We aimed to provide data that supports the use of pCEUS in the thermal ablation of sonographically occult liver tumours.
METHODS:
We conducted a retrospective single-centre study of 35 consecutive patients who underwent pCEUS-guided ablation of 48 liver tumours with a median size of 1.2 cm. Periprocedural, one-month post-treatment and relevant follow-up imaging studies were reviewed. Electronic records were also obtained, with long-term follow-up data of 12-28 months being available for 32 patients.
RESULTS:
36 (75%) tumours that were imperceptible on greyscale US became visible with pCEUS. Overall, complete tumour ablation at one month was 89%. 1 (3%) patient developed a major complication following treatment, while 6 (17%) had minor post-treatment complaints. The local tumour progression rate was 17%, with a median time of 14 months.
CONCLUSION
pCEUS has a role in US-guided thermal ablation of liver tumours, offering a high technical success rate that is comparable to reported data. Additional benefits may include improved procedural time and freedom from ionising radiation.