1.Nursing of patients undergoing skin tissue biopsy on head and face
Haiyan CHEN ; Yue ZHENG ; Miaojian WAN ; Fengxian OU ; Sulian YANG ; Peiying FENG
Modern Clinical Nursing 2015;14(9):28-30
Objective To summarize the experience in nursing patients undergoing skin biopsy on head and face . Method One hundred and twenty patients with head facial dermatosis undergoing skin tissue biopsy were nursed from August 2012 to October 2013. Result All operation for biopsy were completed smoothly, with the cure rate at the first phase 100.0%, healing time 5~7 days, averaged (7.0 ± 3.0)d and no complications. Conclusion For those patients having undergone facial skin tissue biopsy, the nursing measures like psychological nursing, health education before operation, preoperative relief of mental disorder, postoperative wound nursing and health education, prevention of complications are critical for their recovery.
2.Clinical and In Vitro Study of Viaminate in Acne
Yintao LI ; Hong CHEN ; Shiyin LI ; Hongqing CHEN ; Weining HUANG ; Miaojian WAN ; Xiangyang SU ; Sulian YANG ; Fengxian OU
Chinese Journal of Dermatology 1994;0(02):-
Objective To investigate the therapeutic effect of oral viaminate(a vitamine A acid derivative)on acne and its effect on the expression of androgen receptor.Methods Two hundred and eigh-teen patients with acne were allocated to treatment group and control group at random:treatment group was treated by oral viaminate;control group was treated by oral minocycline.The treatment lasted for four weeks.The effect of viaminate on the expression of androgen receptor was studied in COLO-16cells in vitro by using Northern blot or Western blot.Results The therapeutic effect of oral viaminate in treatment group was higher than that in control group(P
3.Expression of cathepsin G in photoaged fibroblasts
Yue ZHENG ; Wei LAI ; Xiaojian WAN ; Chun LU ; Fengxian OU ; Sulian YANG ; Jinling YI ; Meirong LI ; Chongxiu YE
Chinese Journal of Medical Aesthetics and Cosmetology 2010;16(3):183-186
Objective To investigate the role of cathepsin G in photoaged fibroblasts. Methods Human fibroblasts were cultured and induced to premature senescence using UVA + MOP methods. Senescence-associated-β-galactosidase (SA-β-gal) stain was used to evaluate the positive rate of aged cells. The mRNA and protein expression of cathepsin G in photoaged fibroblasts were detected by real-time RT-PCR and Western blot techniques. Results Over 98 % induced cells presented a positive SA-β-gal straining. The expression of cathepsin G, detected by Western blot, was increased to (1. 70±0. 028) times of the control. And RT-PCR revealed that the synthesis of cathepsin G mRNA was also up-regulated to 1. 42±0. 09. Conclusion The results of our study demonstrates a significant correlation between photoaged fibroblasts and cathepsin G. The up-regulation of cathepsin G may play an important role in the damages of extracellular matrix and activation of MMPS in photoaged human skin.
4.Effects of music relaxation combined warm paste on reducing hypothermia, stress response and shivering in cesarean section
Min YUAN ; Sulian WAN ; Leilei FEI
Chinese Journal of Modern Nursing 2018;24(3):320-323
Objective To explore the effects of music relaxation imagination training and warm paste on hypothermia, stress response and shivering during cesarean section.Methods A total of 120 maternals who underwent cesarean section in Huai'an Maternal and Child Health-Care Center of Jiangsu Province from March 2016 to April 2017 were selected as the research objects. According to the different nursing method, the maternals were divided into observation group and control group, with 60 cases in each group. The maternals of the control group were given the conventional nursing intervention, on the basis of which the observation group was given music relaxation imagination training combined with warm paste. The axillary temperature, heart rate and the incidence of shivering of all research objects were statistically analyzed.Results The axillary temperature and heart rate in the observation group were stable during caesarean section. However, the decline of axillary temperature and the fluctuation of heart rate in the control group were obvious. The total incidence rate of shivering of the observation group was 6.67%, which was lower than that of the control group (21.67%), and the difference was statistically significant (χ2=5.74,P=0.03).Conclusions Music relaxation imagination training combined with warm paste can reduce hypothermia during cesarean section, and prevent stress response. In addition, it can effectively prevent intraoperative shivering and reduce the degree of shivering.