sulfuric acid and phosphoric acid, 24 (group 2 GC) were prepared at galvanostatic mode in calcium glycerophosphate and calcium acetate and 24 (group 3 CMP (Calcium Metaphosphate) Coating were prepared at galvanostatic mode in 0.25M sulfuric acid and phosphoric acid followed by CMP coating. Rest of 24 (control group were as a control group of RBM surface. Bone tissue responses were evaluated by resonance frequency analysis (RFA) that were undertaken at 2, 4 and 6 weeks after implant placement in the mandible of mini-pig. Group 1 SP (anodized with sulfuric acid and phosphoric acid implants) demonstrated slightly stronger bone responses than control Group RBM. Group 2 GC (anodized surface with calcium glycerophosphate and calcium acetate implants) demonstrated no difference which were compared with control group. Group 3 GMP (anodized and CMP coated implants) demonstrated slightly stronger and faster bone responses than any other implants. But, all observation result of RFA showed no significant differences between experimental groups with various surface type. Histomorphometric evaluation demonstrated significantly higher bone-to-implant contact for group 2 GC. Significantly more bone formation was found inside threaded area for group 2 GC. It was concluded that group 2 GC (anodized surface with calcium glycerophosphate and calcium acetate implants) showed more effects on the bone tissue responses than RBM surface in initial period of implantation. In addition, CMP showed a tendency to promote bone tissue responses.]]>
Acetates ; Bone and Bones ; Calcium ; Calcium Compounds ; Glycerophosphates ; Mandible ; Osseointegration ; Osteogenesis ; Phosphoric Acids ; Sulfur ; Sulfuric Acids ; Titanium

A 25 year and 7 month old man patient who had Angle's class II division 2 malocclusion combined with anterior crowding of upper & lower part was treated by bioprogressive mechanism. After setting out objectives through the use of V. T. O., we programmed a sequence of mechanic. The possible objectives of treatment in the class II division 2 malocclusion can be listed as follows. 1) Relief of crowding & irregularities. 2) Relief of anterior gingival trauma & correction of interincisal inclination. 3) Correction of buccal segment relationship We'd applied the class II intermaxillary elastics, Quad helix, utility arch wire and sectional arch wire in order to achieve anticipated objectives. As compared with pre & post treatment cephalogram, the result accomplished by this mechanics showed to us that interincisal angle was improved and favorable molar relationship was achieved.
Crowding ; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination ; Humans ; Malocclusion* ; Mechanics ; Molar

Although surgery is the mainstay of local treatment for skin cancer, definitive radiation therapy (RT) has been also applied for patients who are unable to tolerate surgery. Definitive RT regimens usually consist of daily treatment for 4–7 weeks. Such protracted daily RT regimens, however, would not be feasible for non-compliant patients or patients who are unable to make multiple daily trips for weeks. Without treatment, however, skin cancers can continuously progress and cause distressing symptoms. A cyclical hypofractionated RT (QUAD Shot: 14 Gy in 4 fractions, twice-daily treatments with 6 hours interval on 2 consecutive days) can be a practical RT regimen for those patients. In this report, we present the successful treatment course of repeated QUAD Shots in a 79-year-old patient with neglected skin cancer that was disfiguring his face yet declined definitive surgery and protracted RT. We also evaluated and compared biologically equivalent doses between QUAD Shots and conventionally fractionated protracted RT regimens.
Aged ; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination ; Humans ; Skin Neoplasms ; Skin

OBJECTIVEThe purpose of the study was to investigate the prevalence of oral malodor in a group of health cohorts in Chengdu, China by using different diagnostic methods.

METHODSVolatile sulfur compounds (VSCs) level was evaluated by using Halimeter. The organoleptic score and tongue coating index were also evaluated. A questionnaire interview was conducted at the same time.

RESULTSThere were 21.61% subjects whose oral VSCs level were more than 300 ppb. No significant difference was found between male and female for the VSCs values. The subjects with malodor (score > or = 6) evaluated by organoleptic score were 28.91%, and the difference between the male and female was significant (P < 0.05). Further, a significant correlation could be detected between the VSCs level, organoleptic score and tongue coating index (P < 0.05).

CONCLUSIONThe study indicates that nearly one of fourth people suffer from oral malodor. Malodor has significant correlation with tongue coating, so cleaning of tongue dorsum is very important to reduce oral malodor.

Adult ; China ; epidemiology ; Female ; Halitosis ; epidemiology ; Humans ; Male ; Mouth ; Multivariate Analysis ; Prevalence ; Smell ; Sulfides ; analysis ; Sulfur Compounds ; analysis ; Surveys and Questionnaires

Oral malodor may cause a significant social or psychological handicap to those suffering from it. Oral malodor has been correlated with the concentration of volatile sulfur compounds (VSC) produced in the oral cavity. Specific bacteria identified in the production of VSC have been reported and many of these bacteria are commonly suspected periodontal pathogens. The aim of this study was to estimate the change of the VSC concentration after periodontal treatment. Twenty subjects with probing depth (PD) > or =5mm (experimental group) and 20 subjects with PD <5mm (control group) participated. VSC concentration measurement was made with gas chromatography. VSC concentration was measured at pre-treatment, 2 weeks after scaling and 1 month after periodontal treatment(root planning and flap operation). Maximum probing depth and bleeding on probing(BOP) were also examed at pretreatment and 1 month after periodontal treatment. The conclusions were as follow: 1. In the experimental group VSC concentration and CH3SH/H2S ratio were higher than control group. (p<0.05) 2. Both VSC concentration and CH3SH/H2S ratio showed decrease after periodontal treatment. But only CH3SH/H2S ratio after 1 month periodontal treatment was statistically significantly different from pre-treatment. (p<0.05) 3. CH3SH/H2S ratio tended to be on increase according to maximum probing depth and bleeding on probing. Periodontal disease could be a factor that caused oral malodor and oral malodor could be decreased after periodontal treatment.
Bacteria ; Chromatography, Gas ; Hemorrhage ; Mouth ; Periodontal Diseases ; Sulfur Compounds ; Sulfur*

PURPOSE: This study evaluated the adhesion of 10-MDP containing self-etch and self-adhesive resin cements to dentin with and without the use of etch-and-rinse technique. MATERIALS AND METHODS: Human third molars (N=180) were randomly divided into 6 groups (n=30 per group). Conventional (Panavia F2.0, Kuraray-PAN) and self-adhesive resin cements (Clearfil SA, Kuraray-CSA) were bonded to dentin surfaces either after application of 3-step etch-and-rinse (35% H3PO4 + ED Primer) or two-step self-etch adhesive resin (Clearfil SE Bond). Specimens were subjected to shear bond strength test using the universal testing machine (0.5 mm/min). The failure types were analyzed using a stereomicroscope and quality of hybrid layer was observed under a scanning electron microscope. The data (MPa) were analyzed using two-way ANOVA and Tukey's tests (alpha=.05). RESULTS: Overall, PAN adhesive cement showed significantly higher mean bond strength (12.5 +/- 2.3 - 14.1 +/- 2.4 MPa) than CSA cement (9.3 +/- 1.4 - 13.9 +/- 1.9 MPa) (P<.001). Adhesive failures were more frequent in CSA cement groups when used in conjunction with two-step self-adhesive (68%) or no adhesive at all (66%). Hybrid layer quality was inferior in CSA compared to PAN cement in all conditions. CONCLUSION: In clinical situations where bonding to dentin substrate is crucial, both conventional and self-adhesive resin cements based on 10-MDP can benefit from etch-and-rinse technique to achieve better quality of adhesion in the early clinical period.
Adhesives ; Aluminum Compounds ; Calcium Compounds ; Chimera ; Collodion ; Dentin ; Electrons ; Humans ; Molar, Third ; Resin Cements ; Sulfur Compounds

Putrefactive activity within the oral cavity is the principal cause of halitosis. The most common intraoral sites of oral malodor production are tongue, interdental and subgingival areas. The other foci may include faulty restorations, sites of food impaction and abscesses. Periodontal disease frequently involves pathological oral malodor, which is caused mainly by volatile sulfur compounds(VSC), such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide. The purpose of this study is to evaluate the association between oral malodor and periodontal status. Volatile sulfur compounds in mouth air were estimated by portable sulfide monitor(Halimeter(TM)). The results were as follows : 1.The levels of volatile sulfur compounds were significantly greater in a periodontitis group than in a control group(P<0.01). The amounts of VSC in mouth air from patients with periodontal involvement were four times greater than those of the control group. 2.The significant positive correlation was found between VSC concentrations and the number of pocket depth above 4mm(P<0.01), but correlation between VSC concentrations and plaque score was not statistically significant(P>0.05). 3.In the periodontitis group, VSC concentrations of pre-treatment significantly decreased after scaling and root planing(P<0.01). 4.No statistically significant correlation was found between VSC concentrations and sex / age in the periodontitis group. The above results indicate that periodontal disease may play a role as an important factor of oral malodor and deep periodontal pockets are a source of volatile sulfur compounds.
Abscess ; Halitosis ; Humans ; Hydrogen Sulfide ; Mouth ; Periodontal Diseases* ; Periodontal Pocket ; Periodontitis ; Sulfur ; Sulfur Compounds ; Tongue

Halitosis is a very common disease that affects the majority of the population and is characterized by unpleasant odor during expiration. Anaerobic bacteria produce a range of malodorous substances including volatile sulfur compounds. To reduce oral malodor, the amount of oral microorganisms should be managed through brushing, scraping, and use of antibacterial agents. In this study, a mouthwash containing 0.05% cetylpyridinium chloride was tested on 22 candidates with oral malodor for two weeks to confirm oral malodor reduction through the use of antibacterial mouthwashes. Volatile sulfur compound measurements were significantly lower after using the mouthwash than before using it; thus, the mouthwash effectively reduced oral malodor.
Anti-Bacterial Agents ; Bacteria ; Bacteria, Anaerobic ; Cetylpyridinium ; Halitosis ; Mouth ; Mouthwashes ; Odors ; Sterilization ; Sulfur ; Sulfur Compounds

OBJECTIVETo assess the relationship between oral malodor, volatile sulphur compounds (VSCs) levels in the mouth air and periodontal index; the role of tongue in the production of VSCs and halitosis.

METHODS60 periodontitis patients with oral malodor were included. Oral malodor was estimated by organoleptic method (organoleptic rating, OR); VSCs level measurements before and after cleaning the tongue coating were made with a portable sulphide monitor (halimeter), respectively; periodontal probing depth (PD) and the proportion of PD >/= 4 mm sites, bleeding index (BI) and plaque index (PLI) were examined; tongue coating was estimated with thickness (Tt) and area (Ta) on the dorsal surface of tongue.

RESULTSThe correlation was analyzed with Spearman method. There was a significantly positive correlation between OR, VSCs levels and BI, PLI, and Tt, respectively (P < 0.01). OR and VSCs levels was also related with Ta (P < 0.05). There was a weakly correlation between VSCs levels and PD, and the proportion of PD >/= 4 mm sites (r = 0.26, P < 0.05). No correlation between OR and PD, and the proportion of PD >/= 4 mm sites was existed. Reduction of VSCs levels after cleaning tongue coating was statistically significant (t = 10.15, P < 0.01), and also significantly related with thickness and area of tongue coating (P < 0.01).

CONCLUSIONSIn present study, OR and VSCs levels were significantly correlated with gingival inflammation (BI), condition of oral hygiene (PLI), and tongue coating. The relationship between OR, VSCs levels and periodontal probing depth was not found obviously. VSCs levels were significantly reduced after cleaning tongue coating, but the percentage of reduction was less than that of the previous studies.

Dental Plaque Index ; Halitosis ; Humans ; Periodontitis ; Sulfur Compounds

Idod (Immediate Dissolved Oxygen Demand) is a value of the oxygen demand after 15 minute of inoculation by inorganic reducing salts. Industrial development and urban enlargement are bringing water pollution deeply, and industrial waste waters are the source of the inorganic reducing salts. Author investigated the IDOD value change according to the inorganic salts and gained the following results: 1. IDOD value influenced by Na2SO3 is 81.4 ppm. 2. Generally sulfur compounds are highly effecting on IDOD. 3. The nitrite salt had little influence on IDOD.
Industrial Waste ; Oxygen ; Salts* ; Sulfur Compounds ; Water Pollution