In the livestock field, human body sterilizer is one of the methods used to prevent the spread of contagious animal diseases. Disinfection methods include spraying disinfectants, irradiating ultraviolet rays, and generating anions using photocatalysts; however, their effectiveness remains to be clarified. Therefore, in this study, we aimed to verify the pathogen-killing efficacy of the human body sterilizer and propose improvements. Experiments were conducted using a disinfectant spraying model and an ultraviolet single and ultraviolet-photocatalyst composite model. In the bactericidal experiment using Salmonella Typhimurium, the killing effect recorded in both hard and organic conditions did not exceed the standard value. The disinfectant spraying model showed a relatively high effect on the mannequin’s shoulders and arms. Meanwhile, in the virucidal experiment using low pathogenic avian influenza, the killing effect observed in both hard and organic conditions did not exceed the standard value, and no significant difference was observed between the models by site. Notably, the disinfectant spraying model showed a tendency to increase pathogen reduction with increasing exposure time in both bacterial and viral experiments. Human body sterilizer has limitations such as damage from drug exposure, short periods of physical exposure, and the lack of their own disinfection function. Given the current challenges in manufacturing an ideal human body sterilizer, supplementary measures should be implemented to prevent the spread of pathogens by farm entrants. These measures include efficiently utilizing shoe disinfectants, which are crucial in pathogen prevention, and providing disposable clothing.

In the livestock field, human body sterilizer is one of the methods used to prevent the spread of contagious animal diseases. Disinfection methods include spraying disinfectants, irradiating ultraviolet rays, and generating anions using photocatalysts; however, their effectiveness remains to be clarified. Therefore, in this study, we aimed to verify the pathogen-killing efficacy of the human body sterilizer and propose improvements. Experiments were conducted using a disinfectant spraying model and an ultraviolet single and ultraviolet-photocatalyst composite model. In the bactericidal experiment using Salmonella Typhimurium, the killing effect recorded in both hard and organic conditions did not exceed the standard value. The disinfectant spraying model showed a relatively high effect on the mannequin’s shoulders and arms. Meanwhile, in the virucidal experiment using low pathogenic avian influenza, the killing effect observed in both hard and organic conditions did not exceed the standard value, and no significant difference was observed between the models by site. Notably, the disinfectant spraying model showed a tendency to increase pathogen reduction with increasing exposure time in both bacterial and viral experiments. Human body sterilizer has limitations such as damage from drug exposure, short periods of physical exposure, and the lack of their own disinfection function. Given the current challenges in manufacturing an ideal human body sterilizer, supplementary measures should be implemented to prevent the spread of pathogens by farm entrants. These measures include efficiently utilizing shoe disinfectants, which are crucial in pathogen prevention, and providing disposable clothing.

In the livestock field, human body sterilizer is one of the methods used to prevent the spread of contagious animal diseases. Disinfection methods include spraying disinfectants, irradiating ultraviolet rays, and generating anions using photocatalysts; however, their effectiveness remains to be clarified. Therefore, in this study, we aimed to verify the pathogen-killing efficacy of the human body sterilizer and propose improvements. Experiments were conducted using a disinfectant spraying model and an ultraviolet single and ultraviolet-photocatalyst composite model. In the bactericidal experiment using Salmonella Typhimurium, the killing effect recorded in both hard and organic conditions did not exceed the standard value. The disinfectant spraying model showed a relatively high effect on the mannequin’s shoulders and arms. Meanwhile, in the virucidal experiment using low pathogenic avian influenza, the killing effect observed in both hard and organic conditions did not exceed the standard value, and no significant difference was observed between the models by site. Notably, the disinfectant spraying model showed a tendency to increase pathogen reduction with increasing exposure time in both bacterial and viral experiments. Human body sterilizer has limitations such as damage from drug exposure, short periods of physical exposure, and the lack of their own disinfection function. Given the current challenges in manufacturing an ideal human body sterilizer, supplementary measures should be implemented to prevent the spread of pathogens by farm entrants. These measures include efficiently utilizing shoe disinfectants, which are crucial in pathogen prevention, and providing disposable clothing.

In the livestock field, human body sterilizer is one of the methods used to prevent the spread of contagious animal diseases. Disinfection methods include spraying disinfectants, irradiating ultraviolet rays, and generating anions using photocatalysts; however, their effectiveness remains to be clarified. Therefore, in this study, we aimed to verify the pathogen-killing efficacy of the human body sterilizer and propose improvements. Experiments were conducted using a disinfectant spraying model and an ultraviolet single and ultraviolet-photocatalyst composite model. In the bactericidal experiment using Salmonella Typhimurium, the killing effect recorded in both hard and organic conditions did not exceed the standard value. The disinfectant spraying model showed a relatively high effect on the mannequin’s shoulders and arms. Meanwhile, in the virucidal experiment using low pathogenic avian influenza, the killing effect observed in both hard and organic conditions did not exceed the standard value, and no significant difference was observed between the models by site. Notably, the disinfectant spraying model showed a tendency to increase pathogen reduction with increasing exposure time in both bacterial and viral experiments. Human body sterilizer has limitations such as damage from drug exposure, short periods of physical exposure, and the lack of their own disinfection function. Given the current challenges in manufacturing an ideal human body sterilizer, supplementary measures should be implemented to prevent the spread of pathogens by farm entrants. These measures include efficiently utilizing shoe disinfectants, which are crucial in pathogen prevention, and providing disposable clothing.

In the livestock field, human body sterilizer is one of the methods used to prevent the spread of contagious animal diseases. Disinfection methods include spraying disinfectants, irradiating ultraviolet rays, and generating anions using photocatalysts; however, their effectiveness remains to be clarified. Therefore, in this study, we aimed to verify the pathogen-killing efficacy of the human body sterilizer and propose improvements. Experiments were conducted using a disinfectant spraying model and an ultraviolet single and ultraviolet-photocatalyst composite model. In the bactericidal experiment using Salmonella Typhimurium, the killing effect recorded in both hard and organic conditions did not exceed the standard value. The disinfectant spraying model showed a relatively high effect on the mannequin’s shoulders and arms. Meanwhile, in the virucidal experiment using low pathogenic avian influenza, the killing effect observed in both hard and organic conditions did not exceed the standard value, and no significant difference was observed between the models by site. Notably, the disinfectant spraying model showed a tendency to increase pathogen reduction with increasing exposure time in both bacterial and viral experiments. Human body sterilizer has limitations such as damage from drug exposure, short periods of physical exposure, and the lack of their own disinfection function. Given the current challenges in manufacturing an ideal human body sterilizer, supplementary measures should be implemented to prevent the spread of pathogens by farm entrants. These measures include efficiently utilizing shoe disinfectants, which are crucial in pathogen prevention, and providing disposable clothing.

Background: A nationwide outbreak of foot-and-mouth disease (FMD) in South Korea caused massive economic losses in 2010. Since then, the Animal and Plant Quarantine Agency (QIA) has enhanced disinfection systems regarding livestock to prevent horizontal transmission of FMD and Avian influenza (AI). Although the amount of disinfectant used continues to increase, cases of FMD and AI have been occurring annually in Korea, except 2012 and 2013. Objectives: This study measured the concentration of the disinfectant to determine why it failed to remove the horizontal transmission despite increased disinfectant use. Methods: Surveys were conducted from February to May 2017, collecting 348 samples from disinfection systems. The samples were analyzed using the Standards of Animal Health Products analysis methods from QIA. Results: Twenty-three facilities used inappropriate or non-approved disinfectants. Nearly all sampled livestock farms and facilities—93.9%—did not properly adjust the disinfectant concentration. The percentage using low concentrations, or where no effective substance was detected, was 46.9%. Furthermore, 13 samples from the official disinfection station did not use effective disinfectant, and—among 72 samples from the disinfection station—88.89% were considered inappropriate concentration, according to the foot-and-mouth disease virus guidelines; considering the AIV guideline, 73.61% were inappropriate concentrations. Inappropriate concentration samples on automatic (90.00%) and semi-automatic (90.90%) disinfection systems showed no significant difference from manual methods (88.24%). Despite this study being conducted during the crisis level, most disinfectants were used inappropriately. Conclusions This may partially explain why horizontal transmission of FMD and AI cannot be effectively prevented despite extensive disinfectant use.

Abstract: These days abattoirs' hygiene of Korea is regulated by Hazzard Analysis Critical Control Point (HACCP). Although 20 years have been left since first HACCP was adjusted in Korea, 12% of abattoirs got inconsistence on evaluations. Food poisoning caused by bacteria feces like pathogenic Escherichia coli and Salmonella has not decreased. These bacteria on meat crosscontaminate at the abattoir. Therefore, field verification of abattoir's critical control point (CCP) and experiments to find alternative ways of the CCP were conducted. The aerobic bacteria were measured before and after high-pressure water based washing process set as CCP in most abattoirs. Four parts of cattle carcasses were selected to apply sponge-swab method. The effects were < 1 log reduction which is not significant. Lactic acid (LC), chlorine dioxide (ClO2 ) and slightly acidic electrolyzed water (SAEW) were used to measure the effect of reducing bacteria on beef by the different time. LC has 1.24–2.02 log reduction for aerobic bacteria. ClO2 has 1.44–1.96 log reduction for aerobic bacteria. SAEW has 1.1–1.91 log reduction for aerobic bacteria. There was significant difference according to concentrations (p < 0.05). This study presents legitimacy for hygiene improvement of CCP by field verification. In addition, chemical disinfectants that can be mechanically applied have better reduction effects of high-pressure washing.

BACKGROUND: Burden of acute stroke management is increasing according to aging population and advances in the therapeutic time window. However, reduction of resident numbers by the national policy in addition to the underlying low medical charge and reward gradually leaded to a lower rate of application to neurology department. METHODS: We conducted a nationwide survey from May 29, 2017 through July 11, 2017 to evaluate the real-world working conditions and issues of acute stroke management by stroke neurologists in Korea. Of 100 candidates of stroke professors/specialists, a total of 81 physicians participated the survey comprising 40 questionnaires. RESULTS: Stroke care physicians were suffering from heavy work load of inpatient care, outpatient clinic due to shortage of manpower for caring acute stroke. There were only three hospitals (3.7%) where neurologists independently take lead an endovascular therapy. About 43% of the participants were involving in primary duty for acute stroke management stroke, majority of whom (65.7%) were on by themselves. Participants pointed out that the biggest drawbacks were manpower shortage due to lack of residents, and numerous frequencies of primary duty. Approximately 80% of the participants forecasted a dismal future for stroke field. CONCLUSIONS: With the growing incidence of stroke, there is an emerging need for increasing number of neurologists due to contemporary grave shortage of stroke neurologists. It is necessary to investigate the effective demand forecasting for stroke neurologists for the strategy to improve an unmet quality of stroke care with the awareness and help of government.
Aging ; Ambulatory Care ; Brain Infarction ; Forecasting ; Humans ; Incidence ; Inpatients ; Korea ; Neurology ; Reward ; Stroke

BACKGROUND AND PURPOSE: The absence of acute ischemic lesions in diffusion-weighted imaging (DWI) in transient ischemic attack (TIA) patients makes it difficult to diagnose the true vascular etiologies. Among patients with DWI-negative TIA, we investigated whether the presence of a perfusion-weighted imaging (PWI) abnormality implied a true vascular event by identifying new acute ischemic lesions in follow-up magnetic resonance imaging (MRI) in areas corresponding to the initial PWI abnormality. METHODS: The included patients underwent DWI and PWI within 72 hours of TIA and also follow-up DWI at 3 days after the initial MRI. These patients had visited the emergency room between July 2009 and May 2015. Patients who demonstrated initial DWI lesions were excluded. The initial PWI abnormalities in the corresponding vascular territory were visually classified into three patterns: no abnormality, focal abnormality, and territorial abnormality. RESULTS: No DWI lesions were evident in initial MRI in 345 of the 443 TIA patients. Follow-up DWI was applied to 87 of these 345 DWI-negative TIA patients. Initial PWI abnormalities were significantly associated with follow-up DWI abnormalities: 8 of 43 patients with no PWI abnormalities (18.6%) had new ischemic lesions, whereas 13 of 16 patients with focal perfusion abnormalities (81.2%) had new ischemic lesions in the areas of initial PWI abnormalities [odds ratio (OR)=15.1, 95% confidence interval (CI)=3.6–62.9], and 14 of 28 patients with territorial perfusion abnormalities (50%) had new lesions (OR=3.7, 95% CI=1.2–11.5). CONCLUSIONS: PWI is useful in defining whether or not the transient neurological symptoms in DWI-negative TIA are true vascular events, and will help to improve the understanding of the pathomechanism of TIA.
Emergency Service, Hospital ; Follow-Up Studies ; Humans ; Ischemic Attack, Transient* ; Magnetic Resonance Imaging ; Perfusion

BACKGROUND AND PURPOSE: The primary mechanism underlying paramedian pontine infarction (PPI) is atheroma obliterating the perforators. Here, we encountered a patient with PPI in the post-stenotic area of basilar artery (BA) without a plaque, shown by high-resolution magnetic resonance imaging (HR-MRI). We performed an experiment using a 3D-printed BA model and a particle image velocimetry (PIV) to explore the hemodynamic property of the post-stenotic area and the mechanism of PPI. METHODS: 3D-model of a BA stenosis was reconstructed with silicone compound using a 3D-printer based on the source image of HR-MRI. Working fluid seeded with fluorescence particles was used and the velocity of those particles was measured horizontally and vertically. Furthermore, microtubules were inserted into the posterior aspect of the model to measure the flow rates of perforators (pre-and post-stenotic areas). The flow rates were compared between the microtubules. RESULTS: A recirculating flow was observed from the post-stenotic area in both directions forming a spiral shape. The velocity of the flow in these regions of recirculation was about one-tenth that of the flow in other regions. The location of recirculating flow well corresponded with the area with low-signal intensity at the time-of-flight magnetic resonance angiography and the location of PPI. Finally, the flow rate through the microtubule inserted into the post-stenotic area was significantly decreased comparing to others (P<0.001). CONCLUSIONS: Perforator infarction may be caused by a hemodynamic mechanism altered by stenosis that induces a recirculation flow. 3D-printed modeling and PIV are helpful understanding the hemodynamics of intracranial stenosis.
Basilar Artery ; Constriction, Pathologic ; Fluorescence ; Hemodynamics* ; Humans ; Infarction* ; Magnetic Resonance Angiography ; Magnetic Resonance Imaging ; Microtubules ; Plaque, Atherosclerotic ; Rheology ; Silicon ; Silicones