1.Relations of Self-Esteem with Paranoia in Healthy Controls, Individuals at Ultra-High Risk for Psychosis and with Recent Onset Schizophrenia.
Hui Woo YOON ; Yun Young SONG ; Jee In KANG ; Suk Kyoon AN
Korean Journal of Schizophrenia Research 2013;16(2):86-92
OBJECTIVES: Some emotional components, such as self-esteem, depression and anxiety, have been reported to be associated with paranoia in non-clinical population and schizophrenia patients. The aim of this study was to investigate the correlation between self-esteem and paranoia in healthy controls, in ultra-high risk for psychosis and schizophrenia patients. METHODS: 34 subjects with recent onset schizophrenia, 36 subjects with ultra-high risk for psychosis, and 44 healthy volunteers participated in this study. A detailed assessment was made of the paranoia, self-esteem, depression, and anxiety. RESULTS: In all three groups, there were a negative correlation between paranoia and self-esteem, and positive correlations between paranoia and depression and anxiety. In healthy control, lower self-esteem showed a trend to predict higher paranoia, and in ultra-high risk for psychosis, this trend tern on statistically significant level, and in recent onset schizophrenia group, this correlation was disappeared. CONCLUSION: The individual who have lower self-esteem showed higher paranoia tendency under delusional level, but after formation of persecutory delusion, the tendency was disappeared. This result supports the hypothesis that persecutory delusions are a defense against negative affective process.
Animals
;
Anxiety
;
Charadriiformes
;
Delusions
;
Depression
;
Healthy Volunteers
;
Humans
;
Paranoid Disorders*
;
Psychotic Disorders*
;
Schizophrenia*
2.Appropriateness of the Use of Navigation System in Total Knee Arthroplasty
Suk Han JUNG ; Myung Rae CHO ; Suk-Kyoon SONG
Clinics in Orthopedic Surgery 2020;12(3):324-329
Background:
The aim of this study was to evaluate the difference between the planned and verified actual values in total knee arthroplasty (TKA) performed using a navigation system.
Methods:
Sixty patients who underwent primary TKA for knee pain from March 2018 to July 2018 were included in this study.All patients underwent TKA using the latest version of a computer navigation system (Kick ver. 2.6). All TKA procedures were performed by the same surgeon. The appropriateness of the use of navigation system in each of the several steps during the operation was investigated. Implant size was assessed using a preoperative template and after registration of landmarks with the navigation system. Intraoperative measurement was conducted using a femoral sizing implant apparatus. The difference between the planned value based on the navigation system and the actual cutting value was investigated. Intraoperatively confirmed hip-knee-ankle angle was also compared to the angle measured at postoperative 3 months.
Results:
The average time spent on the registration process was 242 seconds (range, 205–345 seconds). Intraoperative femoral component size tended to be smaller than the size recommended by the navigation system. A significant difference between the planned distal femoral cutting level (9.08 ± 0.40 mm) and the verified actual cutting level (9.87 ± 1.39 mm) was identified (p < 0.05).The difference between the planned lateral and medial tibial resection levels (10.12 ± 0.34 mm and 4.47 ± 2.17 mm, respectively) and the verified actual lateral and medial tibial resection levels (9.07 ± 1.45 mm and 3.48 ± 2.00 mm, respectively) was statistically significant. Distal femoral cutting angle in sagittal plane was significantly different but femoral and tibial cutting angles showed no significant difference between the planned and verified values. At full extension, the average coronal alignment of the implant recorded after insertion of the actual implant using the navigation system was 0.23° ± 0.51° varus and showed no significant difference from the alignment measured at postoperative 3 months (0.45° ± 0.58°).
Conclusions
When performing navigation-assisted TKA, surgeons should aware that frequent errors can occur on the femoral cutting level, tibial cutting level, and implant sizing despite its reported advantage in defining the mechanical limb axis.
3.Postoperative Pain and Epithelial Wound Healing in Epi-LASIK With and Without an Epithelial Sheet Preservation.
Sang Kyoon KIM ; Jong Suk SONG ; Hyo Myung KIM
Journal of the Korean Ophthalmological Society 2008;49(12):1894-1900
PURPOSE: To investigate the influence of preservation of an epithelial sheet in Epi-LASIK on postoperative pain and epithelial wound healing time. METHODS: This prospective study included 34 eyes of 17 patients with myopia who received Epi-LASIK. An epithelial flap was created using the epikeratome (Centurion SES, Norwood Abbey EyeCare, Australia). After the stroma was ablated using the MEL 80 (Carl Zeiss Meditec. Germany) excimer laser, the epithelial sheet was replaced on the stromal bed in one randomly selected eye of each patient, and removed in the contralateral eye. The pain scores at postoperative day 0, 1, 2, 5 and the numbers of days for the complete epithelial wound healing were compared between the sheet-preserved and the sheet-removed eyes. At 1 month postoperative, uncorrected visual acuity (UCVA), refractive error and corneal haze were also compared. RESULTS: Pain scores on the day of operation were lower in sheet-preserved group and statistically significant (p=0.01). On postoperative day 1, 2, and 5, pain scores did not reach statistical significance (p=0.24, 0.08, 0.56, respectively). The mean epithelial healing time was 4.88+/-0.93 days for the flap-preserved eyes and 4.29+/-0.77 days for the flap-removed eyes, which showed statistical significance (p=0.01). No significant difference was noted between the 2 groups for mean UCVA, corneal haze and refractive error at 1 month postoperative. CONCLUSIONS: A preserved epithelial sheet reduced early postoperative pain but did not accelerate epithelial wound-healing rate.
Eye
;
Humans
;
Lasers, Excimer
;
Myopia
;
Pain, Postoperative
;
Prospective Studies
;
Refractive Errors
;
Visual Acuity
;
Wound Healing
4.Emotional Dysregulation, Attributional Bias, Neurocognitive Impairment in Individuals at Ultra-High Risk for Psychosis and with Schizophrenia : Its Association with Paranoia.
Nam Wook KIM ; Yun Young SONG ; Jin Young PARK ; Seo Yeon BAEK ; Jee In KANG ; Eun LEE ; Suk Kyoon AN
Korean Journal of Schizophrenia Research 2014;17(2):63-71
OBJECTIVES: Paranoia is a complex phenomenon, affected by a number of factors such as depression, trait anxiety, and attributional bias in schizophrenia. The aim of this study was to explore whether paranoia within continuum of clinical and subclinical states is associated with emotional dysregulation, attributional bias and neurocognitive impairment in whole individuals of normal controls, ultra-high risk (UHR) for psychosis and schizophrenia. METHODS: 101 normal controls, 50 participants at UHR for psychosis, and 49 schizophrenia patients were recruited. All subjects were asked to complete self-reported paranoia scale and emotional dysregulation scales including Rosenberg's self-esteem, Spielberg's state-trait anxiety inventory and Beck depression inventory. The attributional style was assessed by Ambiguous Intentions Hostility Questionnaire (AIHQ). Participants were also requested to complete the comprehensive neurocognitive battery. RESULTS: Multiple linear regression analysis showed that paranoia were found to be associated with emotional dysregulation (state anxiety, trait anxiety and depression), composite blaming bias in ambiguous situation, impairment of attention and working memory in whole participants [F (9, 190)=34.85, p<0.001, adjusted R2=0.61]. CONCLUSION: The main findings suggest that paranoia is a complex affective and cognitive structure that may be associated with emotional dysregulation, blaming bias and attention and working memory impairment in clinical and non-clinical paranoia.
Anxiety
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Bias (Epidemiology)*
;
Depression
;
Hostility
;
Humans
;
Intention
;
Linear Models
;
Memory, Short-Term
;
Paranoid Disorders*
;
Psychotic Disorders*
;
Surveys and Questionnaires
;
Schizophrenia*
;
Weights and Measures
6.A Review of Sarcopenia Pathophysiology, Diagnosis, Treatment and Future Direction
Myung-Rae CHO ; Sungho LEE ; Suk-Kyoon SONG
Journal of Korean Medical Science 2022;37(18):e146-
Sarcopenia is a progressive and generalized loss of skeletal muscle mass and function. The prevalence of sarcopenia was reported to be up to 29% in older persons in the community healthcare setting. Sarcopenia diagnosis is confirmed by the presence of low muscle mass plus low muscle strength or low physical performance. Sarcopenia management options include non-pharmacological and pharmacological approaches. Non-pharmacological approaches include resistance exercise and adequate nutrition. Of the two, resistance exercise is the standard non-pharmacological treatment approach for sarcopenia with significant positive evidence. Some dietary approaches such as adequate intake of protein, vitamin D, antioxidant nutrients, and long-chain polyunsaturated fatty acid have been shown to have positive effects against sarcopenia. Currently, no specific drugs have been approved by the Food and Drug Administration for the treatment of sarcopenia. However, several agents, including growth hormone, anabolic or androgenic steroids, selective androgenic receptor modulators, protein anabolic agents, appetite stimulants, myostatin inhibitors, activating II receptor drugs, β-receptor blockers, angiotensin-converting enzyme inhibitors, and troponin activators, are recommended and have been shown to have variable efficacy. Future research should focus on sarcopenia biological pathway and improved diagnostic approaches such as biomarkers for early detection, development of consistently pre-eminent treatment methods for severe sarcopenia patients, and establishing sensitive measures for predicting sarcopenia treatment response.
7.Sleep Disturbance Strongly Related to the Development of Postoperative Delirium in Proximal Femoral Fracture Patients Aged 60 or Older
Myung-Rae CHO ; Suk-Kyoon SONG ; Cheol-Hwan RYU
Hip & Pelvis 2020;32(2):93-98
Purpose:
Post-fracture sleeping disorders can lead to a deterioration of mental and physical health and delay recovery to pre-fracture status. Here, an analysis was conducted to determine if sleep disturbance is a risk factor for delirium in patients older than 60 years of age with surgically treated proximal femoral fractures.
Materials and Methods:
This retrospective study included 316 patients with surgically treated proximal femoral fractures between January 2014 and December 2016; 33 patients were removed from analysis due to exclusion criteria. Confirmation of delirium was made by a neurologist upon consultation for cognitive impairment and sleeping disorders were confirmed by a doctor or nurse based on the Pittsburgh sleep quality index. Potential risk factors other than a sleep disorder (e.g., history of cognitive impairment, medical illness, preoperational levels of albumin and hemoglobin, transfusion) were also analyzed as variables for the development of delirium.
Results:
The sensitivity and specificity of a sleeping disorder as a risk factor for the development of delirium were 0.75 and 0.76, respectively; the positive and negative predictive values were 0.64 and 0.93, respectively. A sleeping disorder was significantly related to the development of the delirium (odds ratio adjusted for age, sex and body mass index was 5.78, P<0.01). In those with a history of cognitive impairment, the adjusted odds ratio for the development of delirium was 6.03 (P<0.01).
Conclusion
Sleeping disorders occurring after a surgically repaired proximal femoral fracture in patients 60 years of age or older could be an independent predictive factor of delirium.
8.Recessive allelic loss in colorectal cancer tissue.
Won Il CHO ; Sung Jin YOO ; Suk Kyoon CHANG ; Seung Nam KIM ; Young Taek SONG ; Jae Hak LEE ; Sang Yong JOO
Journal of the Korean Cancer Association 1993;25(6):848-854
No abstract available.
Colorectal Neoplasms*
;
Loss of Heterozygosity*
9.Relation Among Parameters Determining the Severity of Bronchial Asthma.
Sook Young LEE ; Seung June KIM ; Seuk Chan KIM ; Soon Suk KWON ; Young Kyoon KIM ; Kwan Hyoung KIM ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 2000;49(5):585-593
BACKGROUND: International consensus guidelines have recently been developed to improve the assessment and management of asthma. One of the major recommendations of these guidelines is that asthma severity should be assessed through the recognition of key symptoms, such as nocturnal waking, medication requirements, and objective measurements of lung function. Differential classification of asthma severity would lead to major differences in both long term pharmacological management and the treatment of severe exacerbation. METHODS: This study examined the relationship between the symptom score and measurements of FEV1 and PEF when expressed as a percentage of predicted values in asthmatics(n=107). RESULTS: The correlation of FEV1% with PEFR% was highly significant(r=0.83, p<0.01). However, there was agreement in terms of the classification of asthma severity in 76.6% of the paired measurements of FEV1% and PEFR%. Agreement in the classification of asthma severity was also found in 57.1% of the paired analysis of FEV1% and symptom score. 39% of the patients classified as having moderate asthma on the basis of FEV1% recording would be considered to have severe asthma if symptom score alone were used. Low baseline FEV1 and high bronchial responsiveness were associated with a low degree of perception of airway obstruction. CONCLUSION: The relationships between the symptom score, PEFR and FEV1 were generally poor. When assessing asthma severity, age, duration, PC20, and baseline FEV should be considered.
Airway Obstruction
;
Asthma*
;
Classification
;
Consensus
;
Humans
;
Lung
;
Peak Expiratory Flow Rate
10.A Statistical Study on Urolithiasis II.
Hee Yong LEE ; Joon Tong KIM ; Young Kyoon KIM ; Suk Kee JOO ; Hak Song LEE
Korean Journal of Urology 1963;4(1):49-56
A statistical analysis was made on 468 cases of urolithiasis during the period April 1951 to September 1962, and the following data were obtained: 1. The incidence of the patients with the stones was 2.25 percent of total urological outpatients and 25.4 percent of the ward patients. 2. Incidences of urinary calculi are increasing year by year; 3.6 per cent in 1954, 12.8 per cent in 1958, and 20.7 per cent in 1962. 3. The incidence of stones in the upper urinary tract seemed to increase significantly while that of the lower tract did not. The ratio of upper urinary tract calculi over ones in the lower tract (24 : 76 in 1954), reversed with greatly increasing incidence of upper urinary tract calculi (69: 31 in 1962). 4. These stones consisted of renal stone in 14.5 per cent, ureteral stone in 45.6 per cent, bladder stone in 25.6 per cent and urethral stone in 13 per cent. 5. The stones were most commonly found between the ages of 20 to 50. The upper urinary tract calculi were more frequently seen in young adults but in aged and children lower urinary tract calculi were common. 6. The stones were found to occur predominantly in males than in females and the ratio was 5.4 : 1. 7. The upper urinary tract calculi occurred both in the left and right sides with approximately equal frequency. It was estimated that bilateral urinary calculi occurred in 6 per cent of the cases. 8. Multilocations of the stones in the urinary tracts occurred in 7 per cent of the total stones. 9. Seventy-three per cent of the ureteral stones were lodged in the lower ureter. 10. The results of qualitative chemical examination of stones were calcium oxalate in 30.7 per cent, calcium phosphate in 28.5 per cent, apatite in 19.3 per cent, uric acid and calcium phosphate in 9.1 per cent, uric acid and calcium oxalate in 6.8 per cent, uric acid in 3.4 per cent, and carbonate in 2.2 per cent. 11. Three hundred and nine of 468 cases were treated in the clinic. Spontaneous passage occurred in 10.4 per cent, 41.6 per cent were expelled following instrumental manipulation and 18.6 per cent were subjected to surgical intervention.
Calcium
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Calcium Oxalate
;
Calculi
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Carbon
;
Child
;
Female
;
Humans
;
Incidence
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Male
;
Outpatients
;
Statistics as Topic*
;
Ureter
;
Uric Acid
;
Urinary Bladder Calculi
;
Urinary Calculi
;
Urinary Tract
;
Urolithiasis*
;
Young Adult