1.The Efficacy of Vaginal Fluid B-hGC Levels for Detecting Premature Rupture of Membranes.
Korean Journal of Perinatology 1998;9(4):415-420
Premature rupture of membranes(PROM) means the rupture of amniotic membranes at any time prior to labor during the gestational period. The dilemma of correctly diagnosing rupture of the fetal membranes is well known as the consequences of management based on an incorrect diagnosis. This study was undertaken to determine if the measurement of B-hCG levels in the vaginal fluid is useful for the diagnosis of premature rupture of membranes. HCG is synthesized and secreted by the placental syncytiotrophoblast and it is normally found in amniotic fluid, maternal urine and blood. We used B-hCG for diagnosis of PROM to exclude the cross reaction with other hormones. After irrigating the posterior vaginal fornix with 3 ml of sterile saline and obtaining vaginal washings, we measured B-hCG levels. The groups were classified normal group(group I), confirmed PROM group(group II ), and suspicious PROM group(groupIII) during the third trimester. The median and 95% confidence intervals(CIS) of vaginal fluid B-hCG in each group(normal, confirmed PROM, suspicious PROM group) were 30.99mIU/ml(range: 0.32-209.89mIU/ml), 188.61mIU/ml(range: 9.65-2095.00mIU/ml), 69.63mIU/ml(range 4.76-349.56mIU/ml). There was significant difference between normal and confirmed PROM group(p<0.05), sensitivity was 95.00%, specificity 80.00%, positive predictive value 82.60%, negative predictive value 94.12%, and accuracy 87.50%, using threshold value of 60mIU/ml. There was significant difference between normal and suspicious PROM group(p<0.05) but the result of the B-hCG was not used in the obstetric decision. In terms of these results, the B-hCG level in vaginal fluid is a useful marker of PROM during the third trimester. A new technic is proposed to confirm the diagnosis of rupture of the membranes based on the introduction of B-hCG in vaginal fluid.
Amnion
;
Amniotic Fluid
;
Cross Reactions
;
Diagnosis
;
Extraembryonic Membranes
;
Female
;
Humans
;
Membranes*
;
Pregnancy
;
Pregnancy Trimester, Third
;
Rupture*
;
Sensitivity and Specificity
;
Trophoblasts
2.The role of cartilage canals to the initial osteogenesis of ossification centers of the talus in the human fetus.
Kang Suk KOH ; Baik Yoon KIM ; Jae Rhyong YOON
Korean Journal of Physical Anthropology 1993;6(1):47-71
No abstract available.
Cartilage*
;
Fetus*
;
Humans*
;
Osteogenesis*
;
Talus*
3.Relations of Self-Esteem with Paranoia in Healthy Controls, Individuals at Ultra-High Risk for Psychosis and with Recent Onset Schizophrenia.
Hui Woo YOON ; Yun Young SONG ; Jee In KANG ; Suk Kyoon AN
Korean Journal of Schizophrenia Research 2013;16(2):86-92
OBJECTIVES: Some emotional components, such as self-esteem, depression and anxiety, have been reported to be associated with paranoia in non-clinical population and schizophrenia patients. The aim of this study was to investigate the correlation between self-esteem and paranoia in healthy controls, in ultra-high risk for psychosis and schizophrenia patients. METHODS: 34 subjects with recent onset schizophrenia, 36 subjects with ultra-high risk for psychosis, and 44 healthy volunteers participated in this study. A detailed assessment was made of the paranoia, self-esteem, depression, and anxiety. RESULTS: In all three groups, there were a negative correlation between paranoia and self-esteem, and positive correlations between paranoia and depression and anxiety. In healthy control, lower self-esteem showed a trend to predict higher paranoia, and in ultra-high risk for psychosis, this trend tern on statistically significant level, and in recent onset schizophrenia group, this correlation was disappeared. CONCLUSION: The individual who have lower self-esteem showed higher paranoia tendency under delusional level, but after formation of persecutory delusion, the tendency was disappeared. This result supports the hypothesis that persecutory delusions are a defense against negative affective process.
Animals
;
Anxiety
;
Charadriiformes
;
Delusions
;
Depression
;
Healthy Volunteers
;
Humans
;
Paranoid Disorders*
;
Psychotic Disorders*
;
Schizophrenia*
4.A Case Report of Osteoid Osteoma
Eun Woo LEE ; Sae Yoon KANG ; Sae Il SUK
The Journal of the Korean Orthopaedic Association 1969;4(3):65-68
A case of osteold osteoma was presented because of its rarity in number particularly in localization of tumor, that is, subperiosteal in position. Also we could treat the patient successfully by surgical intervention and the removed specimen preserved beautifully all the character and contour of the tumor grossly and microsoopically.
Humans
;
Osteoma
;
Osteoma, Osteoid
5.A Clinical Study of 44 Hip Fractures
Sae Yoon KANG ; Eun Yong LEE ; Se Il SUK
The Journal of the Korean Orthopaedic Association 1970;5(2):49-54
This is to present 44 cases of hip fractures, of these 28 being fractures of femoral neck and the remainder, intertrochanteric, which were treated at the Department of Orthopedic Surgery, Seoul National University Hospital for four years and 8 months from Jan. 1965 to Aug. 1969. 1. There were 33 males. and 11 females in the series. 26 cases(59.1) were over 51 years of age. 2. The femoral neck fractures were treated by means of Smith Petersen nailing in 16 cases, modified Girdlestone hip arthroplasty in 3 cases, Austin-Moore hip prosthesis in 6 cases and other methods in 3 cases. 3. Modified Girdlestone hip arthroplasty could be a treatment of choice for femoral neck fracture requiring hip arthroplasty for those unsuitable for extensive surgery. 4. The intertrochanteric fractures of femur except for 3 unstable fractures were treated successfully with the Smith-Petersen nail and plate, following anatomical reduction of fracture. In 3 unstable fractures, satisfactory stabilization and internal fixation was obtained by the method of medial displacement of proximal part of distal fragment of fracture.
Arthroplasty
;
Clinical Study
;
Female
;
Femoral Neck Fractures
;
Femur
;
Femur Neck
;
Hip Fractures
;
Hip Prosthesis
;
Hip
;
Humans
;
Male
;
Methods
;
Orthopedics
;
Seoul
6.Anesthesia for ambulatory pediatric patients.
Jung Soo YOON ; Tae Hoon KANG ; Hong Suk YANG
The Korean Journal of Critical Care Medicine 1993;8(1):53-58
No abstract available.
Anesthesia*
;
Humans
7.Acute Neuropathic Joint in Diabetic Foot: Plain Radiographic Findings.
Heung Sik KANG ; Yong Kyu YOON ; Dae Young YOON ; Jung Suk SIM ; Chu Wan KIRN
Journal of the Korean Radiological Society 1994;30(5):929-933
PURPOSE: To determine the plain film findings of acute neuropathic joint in diabetic foot. MATERIALS AND METHODS: Acute neuropathic joint in diabetic foot was considered when fragmentation of the articular ends of bone and subluxation of the affected joint developed within eight weeks after clinical onset of diabetic gangrene. Eight toes of six diabetics were satisfactory to our criteria. We analyzed plain radiographic findings of the affected joint and soft tissue, interval changes in follow-up radiographs, and deformities after healing. RESULTS: The time interval between clinical onset of gangrene and bone destruction ranged from 2 weeks to 4 weeks(mean 2.6 weeks). Plain radiographs showed fragmentation of the articular ends, subluxation, and soft tissue swelling of the metatarsophalangeal joint or interphalangeal joint. The significant feature of these patients was rapid progression of the lesions. Clinically, all patients had diabetic gangrene in affected toes, however, there was no evidence of osteomyelitis in our series. Amputation was done in 2 cases, and lesions in 3 of the remaining 4 cases were repaired spontaneously with regression of gangrene, leaving radiological residua such as pointed-end, tapered-end, and ball and socket deformity. CONCLUSION: Rapid disorganization of the joint with associated evidence of soft tissue gangrene in plain radiograph is believed to be valuable for the diagnosis of diabetic osteoarthropathy.
Amputation
;
Congenital Abnormalities
;
Diabetic Foot*
;
Diagnosis
;
Follow-Up Studies
;
Gangrene
;
Humans
;
Joints*
;
Metatarsophalangeal Joint
;
Osteomyelitis
;
Toes
8.Regulation mechanisms of inflammatory response induced by Fc? stimulation in human monocytes and monocytic cell line, thp1.
Kang Soon YOON ; Suk Ran YOON ; Choong Eun LEE ; Hyung Soon KIM ; Kwang Ho PYUN
Korean Journal of Immunology 1993;15(2):163-171
No abstract available.
Cell Line*
;
Humans*
;
Monocytes*
9.Congenital Fiber Type Disproportion Myopathy: A case report .
Sung Hye PARK ; Kwang Kuk KIM ; Suk Yoon KANG ; Shin Kwang KANG
Korean Journal of Pathology 1999;33(4):303-306
Authors report a typical case of congenital fiber type disproportion (CFTD) with unique clinicopathologic characteristics. The patient was a 13-year-old boy who presented with weakness of lower extremities, especially proximal muscle, since his infancy. He has suffered from severe scoliosis which got worse since the age of 12. He showed mild dysarthria, high arched palate, and fish face. All routine laboratory data were within normal limits. EMG findings suggested myopathy. The muscle biopsy revealed fiber type disproportion with type 1 predominance. While most of the type 1 myofibers were atrophic or normal in size, the type 2 fibers showed universal hypertrophy. The difference of mean diameter between the larger and the smaller fibers was 27.9%. The patient's clinicopathologic settings fulfilled the criteria of CFTD.
Adolescent
;
Biopsy
;
Dysarthria
;
Humans
;
Hypertrophy
;
Lower Extremity
;
Male
;
Muscular Diseases*
;
Myopathies, Structural, Congenital*
;
Palate
;
Scoliosis
10.Immunoblot observation of antigenic protein fractions in Paragonimus westermani reacting with human patients sera.
Sung Hwan KIM ; Yoon KONG ; Suk Il KIM ; Shin Yong KANG ; Seung Yull CHO
The Korean Journal of Parasitology 1988;26(4):239-243
: In order to observe the antigenic fractions in saline extract of adult Paragonimus westermani, proteins in the crude extract were separated by sodium dodecyl sulfate-polyacylamide gel electrophoresis (SDS-PAGE) in reducing conditions. The separated protein fractions were transferred to nitrocellulose paper on which 20 sera from human paragonimiasis were reacted and immunoblotted. Out of 15 stained protein bands in SDS-PAGE, 7 reacted with the sera. Of 14 reacted bands, 30 kilodalton(kDa) band was the most frequently reacted (95%) and was a strong antigen. Protein bands of 23 and 46 kDa were also strong antigens. Bands of over 150 kDa, 120 kDa, 92 kDa, 86 kDa, 74 kDa, 62 kDa, 51 kDa, 32 kDa, 28 kDa, 16.5 kDa and 15.5 kDa were also reactive but their frequencies of the reaction were variable.
parasitology-helminth-trematoda
;
Paragonimus westermani
;
immunology
;
antigen
;
electrophoresis