1.28-year old Polycythemia Vera patient presenting with Cerebral Infarction.
Ho Suk OH ; Myung Ju AHN ; Hee Tae KIM ; Woong Soo LEE
Korean Journal of Medicine 2002;62(4):482-483
No abstract available.
Adult*
;
Cerebral Infarction*
;
Humans
;
Polycythemia Vera*
;
Polycythemia*
2.Renal Replacement Therapy in Korea: Insan Memorial Registry 1997.
Korean Journal of Nephrology 1999;18(1):1-15
The status of renal replacement therapy in Korea as follows ; 1) The response rate to questionaire was 57.9% of the 226 hemodialysis centers in Korea and data file was sent in the 62.4% of responder. 2) The number of dialysis center was 226 and the number of hemodialysis machine was 3,507 and annual increasing rate were 8,7%, 14.0%, respectively. 3) The total number of ESRD patients was 20,244 and prevalance and incidence of ESRD were 431.9 and 101.1 patients per million population(ppm). 4) The proportion of renal replacement therapy was hemodialysis(HD) 53.3%, peritoneal dialysis(PD) 17.196, renal transplants(KT) 29.5%. 5) The proportion of long-term and elderly patients was markedly increased comparing 1985 (long term dialysis 20% vs. 2%, over 60 year old patients 26.2% vs. 13.8%. 6) The primary cause of renal disease was diabetic nephropathy 34.09o, chronic glomerulone-phritis 20.8%, hypertensive nephropathy 15.7%. 7) The mean BMI(body mass index,' kg/M)in over 18 year old patients was 20.7+/-2.7 kg/M in the HD and 22.23.0 kg/M in the PD. 71.9M of HD patients and 73.2% of PD were in the normal range (18.5-24.9). 8) The fistula survival rate was 6 month 93.4%, 1 yr 91.7%, 3 yr 87.6%, 5 yr 84.7%. 9) The cause of death were cardiac disease 31.8%, miscellaneous 23.5%, vascular disease 17.2%, infection 14.2%, liver disease 1.2%, social cause 5.9%.
Adolescent
;
Aged
;
Automatic Data Processing
;
Cause of Death
;
Diabetic Nephropathies
;
Dialysis
;
Fistula
;
Heart Diseases
;
Humans
;
Incidence
;
Kidney Failure, Chronic
;
Korea*
;
Liver Diseases
;
Middle Aged
;
Reference Values
;
Renal Dialysis
;
Renal Replacement Therapy*
;
Survival Rate
;
Vascular Diseases
3.The Inhibition of Stress-Induced c-fos Expression by Superior Cervical Ganglion Block in Rat Brain.
Hyun Ju JUNG ; Chong Min PARK ; Dong Suk CHUNG ; Myung Ja AHN ; Hyung Jin BYUN
Korean Journal of Anesthesiology 1997;33(6):1029-1036
BACKGROUND: Using c-fos expression one of the immediate early gene, as a marker of altered neuronal response, we investigated the effect of superior cervical ganglion block (SCGB) exhibiting the same effect of SGB of human on the activity of several brain regions which are considered as located on autonomic neural pathway and neuroendocrine axis in rat. METHOD: The 48 Sprague-Dawley strain rats were divided into 4 groups, as saline/stress (control) group, SCGB/stress (tested) group, saline group, SCGB group. Superior cervical ganglion block was conducted in the SCGB/stress group and SCGB group while saline/stress and saline group were sham operated. After then restraint stress was imposed on the animals of SCGB/stress group and saline/stress group. And 2 hour after injection (saline, SCGB group) or restraint stress (saline/stress, SCGB/stress group), c-fos protein (Fos) was localized by immunocytochemistry. RESULTS: Much stronger Fos immunoreactivity was induced in the several brain region of control group rats compared to other three groups and the numbers of Fos positive cell count of tested group were significantly decreased in paraventricular hypothalamic nucleus (p<0.01), A5 (p<0.01), raphe pallidus (p<0.05), nucleus tractus solitaius (p<0.01) compared to control group. CONCLUSION: This study demonstrate that superior cervical ganglion block attenuates stress induced neuronal activities of paraventricular hypothalamic nucleus, A5, raphe pallidus, nucleus tractus solitarius.
Animals
;
Axis, Cervical Vertebra
;
Brain*
;
Cell Count
;
Genes, vif
;
Humans
;
Immunohistochemistry
;
Neural Pathways
;
Neurons
;
Paraventricular Hypothalamic Nucleus
;
Rats*
;
Rats, Sprague-Dawley
;
Solitary Nucleus
;
Superior Cervical Ganglion*
4.Hyperlipidemia in kidney transplant recipients.
Dong Chan JIN ; Suk Ju AHN ; Je Young WOO ; Yong Soo KIM ; Suk Young KIM ; Eui Jin CHOI ; Yoon Sik CHANG ; Young Suk YOON ; Byung Kee BANG
Korean Journal of Nephrology 1993;12(2):156-164
No abstract available.
Hyperlipidemias*
;
Kidney*
;
Transplantation*
5.Effect of immune complex on the cytokine production and host resistance of mice against intracellular bacteria.
Hyun Chul LEE ; Saeng Koo CHO ; Tae Ju HWANG ; In Chol KANG ; Jong Suk OH ; Tae Hew AHN
Korean Journal of Immunology 1993;15(1):11-23
No abstract available.
Animals
;
Antigen-Antibody Complex*
;
Bacteria*
;
Mice*
6.A Case of Fasciolia Liver Abscess with Severe Eosinophilia in a Child.
Jin A JUNG ; Ju Suk LEE ; Kang Mo AHN
Pediatric Allergy and Respiratory Disease 2003;13(3):199-203
A case of child fasciola liver abscess was reported. This case was a. A 5-years-old boy who had a history of fever and abdominal pain for 2 days. There was eosinophilia (15%) and an abdominal ultrasound demonstrated heterogenous hypoechoic mass in the liver. He was diagnosed with bacterial liver abscess and was treated with Unasyn, Amikin, Cefotaxime, and metronidazole. But, the fever did not subside completely and blood eosinophil count was increased to 50%. New hypoechoic lesion in the liver was revealed on the follow-up abdominal ultrasound. Liver biopsy was done and it revealed eosinophil infiltration. Also, there was eosinophil infiltration (20%) in his bone marrow. The serologic test for parasite-specific IgG antibody by micro-ELISA confirmed the diagnosis of Fasciola hepatica infection. He was successfully treated for two days with oral Triclabendazole, 15 mg/kg, daily. Blood eosinophil count was down to 10% and there was no abnormal lesion in the liver on abdominal ultrasound finding.
Abdominal Pain
;
Amikacin
;
Biopsy
;
Bone Marrow
;
Cefotaxime
;
Child*
;
Diagnosis
;
Eosinophilia*
;
Eosinophils
;
Fasciola
;
Fasciola hepatica
;
Fascioliasis
;
Fever
;
Follow-Up Studies
;
Humans
;
Immunoglobulin G
;
Liver Abscess*
;
Liver*
;
Male
;
Metronidazole
;
Serologic Tests
;
Ultrasonography
7.Herpes simplex virus and varicella zoster virus infection in renal transplant recipients.
Sun Ae YOON ; Soo Hun PARK ; Chul Woo YANG ; Suk Ju AHN ; Young Suk YOON ; Byung Kee BANG ; Young Bok KOH
The Journal of the Korean Society for Transplantation 1991;5(1):83-89
No abstract available.
Chickenpox*
;
Herpes Simplex*
;
Herpesvirus 3, Human*
;
Simplexvirus*
;
Transplantation*
8.Herpes simplex virus and varicella zoster virus infection in renal transplant recipients.
Sun Ae YOON ; Soo Hun PARK ; Chul Woo YANG ; Suk Ju AHN ; Young Suk YOON ; Byung Kee BANG ; Young Bok KOH
The Journal of the Korean Society for Transplantation 1991;5(1):83-89
No abstract available.
Chickenpox*
;
Herpes Simplex*
;
Herpesvirus 3, Human*
;
Simplexvirus*
;
Transplantation*
9.Th17 Responses Are Not Induced in Dextran Sodium Sulfate Model of Acute Colitis.
Yoon Suk KIM ; Min Ho LEE ; Ahn Seung JU ; Ki Jong RHEE
Immune Network 2011;11(6):416-419
Dextran sodium sulfate (DSS) is a widely used chemical model for inflammatory bowel disease (IBD). It is thought that imbalances in the T helper (Th) cell subsets contribute to IBD. Recent studies suggest that the acute DSS-colitis model is polarized toward a Th1/Th17 profile based on RT-PCR analysis of colonic tissues. In the current study we determined whether colonic Th cells from DSS-colitis mice were skewed toward the Th17 profile. Mice were treated with 5% DSS for 7 days and colonic T cells isolated and examined for production of IFN-gamma (Th1 cell), IL-4 (Th2 cell) and IL-17 (Th17 cell) by intracellular flow cytometry. We found that the percentage of colonic Th17 cells were similar to non-treated controls but the percentage of Th1 cells were elevated in DSS-colitis mice. These results suggest that in the acute DSS-colitis model the colonic Th cells exhibit a Th1 profile and not a Th17 profile.
Animals
;
Colitis
;
Colon
;
Dextrans
;
Flow Cytometry
;
Inflammatory Bowel Diseases
;
Interleukin-17
;
Interleukin-4
;
Mice
;
Models, Chemical
;
Sodium
;
Sulfates
;
T-Lymphocytes
;
Th1 Cells
;
Th17 Cells
10.Phase II Study of Oxaliplatin, 5-fluorouracil, and Leucovorin in Relapsed or Metastatic Colorectal Cancer as Second Line Therapy.
Duk Joo LEE ; Ho Suk OH ; Jung Hye CHOI ; Young Yeul LEE ; In Soon KIM ; Myung Ju AHN
Cancer Research and Treatment 2006;38(4):201-205
PURPOSE: The purpose of the study was to assess the efficacy and safety of biweekly oxaliplatin in combination with leucovorin (LV)-modulated bolus plus infusion of 5-fluorouracil (5-FU) in patients with relapsed or metastatic colorectal cancer (CRC) as a second line therapy. MATERIALS AND METHODS: Between November 2002 and October 2005, 26 patients with histologically confirmed relapsed or metastatic CRC were enrolled. All patients were previously treated with irinotecan-based combination chemotherapy. The chemotherapy regimen consisted of oxaliplatin 85 mg/m2 on day 1; LV 200 mg/m2 on days 1 and 2; and 5-FU 400 mg/m2 bolus IV with 600 mg/m2 with a 22-hour infusion on days 1 and 2 every 2 weeks. RESULTS: The median age of the 26 patients was 50.5 years (range, 31~72). Their metastatic sites included: the liver (42.3%), peritoneum (26.9%), lung (23.1%) and ovary (7.7%). Twenty five patients were evaluated for their response. Four patients achieved partial responses and 15 patients had stable disease. The overall response rate was 16% (95% confidence interval; 1.7~30.3%). The median follow-up duration for the surviving patients was 7.4 months (range, 2.08~21.2). Median overall survival (OS) and 1-year OS rates were 16.7 months and 63.9%, respectively. The most common hematological toxicities were: NCI grade I/II leucopenia (49.3%), grade I/II neutropenia (41%) and grade I/II anemia (65.2%). The main non-hematological toxicities were: grade I/II peripheral neuropathy (16.1% and 21.5%, respectively) and nausea/ vomiting (23.6%/18.5%). There was no life-threatening toxicity. CONCLUSION: The oxaliplatin, 5-FU and LV combination chemotherapy, scheduled as a biweekly protocol, was effective and well tolerated in the treatment of relapsed or metastatic colorectal cancer patients as second line chemotherapy.
Anemia
;
Colorectal Neoplasms*
;
Drug Therapy
;
Drug Therapy, Combination
;
Female
;
Fluorouracil*
;
Follow-Up Studies
;
Humans
;
Leucovorin*
;
Liver
;
Lung
;
Neutropenia
;
Ovary
;
Peripheral Nervous System Diseases
;
Peritoneum
;
Vomiting