Hereditary angioedema is a rare genetic disease transmitted with a autosomal dominant trait result of a quantitative or functional defect of Cl inhibitor. We report three cases of heriditary angioedema from the same famly respectively the 35-year-old sister, the younger bn)ther of 32, and the younger sister of 20 The older sister died due to her airway being obstructel by acute laryngeal edema, and her you igirbrother and sister experienced recurrent episodes oswelling on the hand and forearm. The ore we examined the two patients serum complement levils to confirm diagnosis. In both, the r;ults showed decreased levels of Cl inhibitor and C4 which are the evidence of hereditary a giedema. The younger sister has been administered danazol (600mg/day) to prevent angioedem or 8 weeks, and we have not yet found a recurrenc of he symptoms. However, well cont ol the dosage of danazol because amenorchea has developec.
Adult ; Angioedema ; Angioedemas, Hereditary* ; Complement System Proteins ; Danazol ; Diagnosis ; Forearm ; Hand ; Humans ; Laryngeal Edema ; Siblings

Hemorrhagic complications associated with aspirin use occur primarily at skin or gastrointestinal sites but can occasionally occur in the central nervous system. In particular, spontaneous spinal epidural hemorrhage (SSEH) associated with aspirin is very rare. We report a case of low-dose (100 mg daily) aspirin-related SSEH that was successfully treated with medical management. Our case indicates that low-dose aspirin could induce SSEH and that conservative treatment with close observation and repeated imaging studies should be considered in cases with neurological improvement or mild deficits.
Aspirin ; Central Nervous System ; Hematoma ; Hematoma, Epidural, Spinal ; Skin

Mucormycosis is a relatively uncommon opportunistic fungal infection that occurs more commonly in patients with immunosuppression and diabets mellitus, particularly those with ketoacidosis. Successful therapy for rhinoorbital mucormycosis requires early diagnosis, correction of predisposing conditions, prompt use of amphotericin B, and aggressive surgical debridement. We experienced a 56-years-old poorly controlled diabetic woman with rhinoorbital mucormycosis that was successfully treated with intraconal amphotericin B irrigation and packing without exenteration.
Abscess* ; Amphotericin B* ; Debridement ; Drainage* ; Early Diagnosis ; Female ; Humans ; Immunosuppression ; Ketosis ; Mucormycosis*

OBJECTIVES: This paper presents the information on the incidence of cancer from the population-based cancer resistry in Kangwha County. Material and METHODS: This investigation is based on Kangwha cancer registry. The data included cases of cancer diagnosed from 1986 through 1992. The diagnosis of cancer was confirmed by a team of physicians and nurses with the medical records kept in the clinics and hospitals based on the diagnostic criteria recommended by WHO. Home visitings were also made to cancer patients confirmed in every 6 months for the follow up and for the collection of relevant information directly from the patients. RESULTS: A total of 992 cancer cases were registered during 1986 - 1992. The age-adjusted cancer incidence rate of all site is 201.7 in men and 110.7 in women. The most common cancer is the stomach cancer in both sexes. The age-adjusted incidence rate of the stomach cancer is 65.9 in men and 25.0 in women per 100,000 population. The lung cancer(33.8) and liver cancer(27.7) are next common cancers in men. The cervical cancer(21.8) and lung cancer(8.4) are next in women. CONCLUSION: The most common cancer is the stomach cancer in both sexes. The annual age-adjusted incidence rate of the stomach cancer is 65.9 in men and 25.0 in women per 100,000 population.
Diagnosis ; Female ; Follow-Up Studies ; House Calls ; Humans ; Incidence* ; Liver ; Lung ; Male ; Medical Records ; Stomach Neoplasms

No abstract available.
Kidney Transplantation*

No abstract available.
Cell Line* ; Humans* ; Monocytes*

Stomach of 34 year old man showed an early stage of the cancer with slight involvement of the superficial part of the inner muscle layer and accompanied with one metastatic lymph node. The cancer is that of medium differentiated adenocarcinoma. There is an heavy infiltration of lymphocytes mixed with histiocytic mononuclear cells and multinucleated giant cells. Some giant cells appear as Langhans' type suggesting phagocytic cells of their origin containing PAS positive materials in the cytoplasma. In other places, they appear as atrophic cancer nests suggesting that these tumor nests were arrested and undergone to regressive cellular process because of the over-whelming immunological pressure by the host.
Male ; Humans ; Neoplasm Metastasis ; Stomach Neoplasms

No abstract available.
Neurofibromatoses* ; Pseudarthrosis* ; Radius*

BACKGROUND: Occupational dermatoses are increasing tendency in Korea. But there were only a few reports about occupational dermatoses in Korean dermatologic literatures. OBJECT: For the effective preventive method and having interest in occupational dermatoses, we have done wide ranged basic study about the occupational dermatoses for 3 years in a semiconductor industry. METHODS: The number of workers of the semiconductor industry was 10,500(male 5,000, female 5,500) and finally the number of analysed patients in this survey was 2,736. A dermatologist attended regularly at the clinic in a semiconductor industry once a week for the duration of 3 years from June 1992 to May 1995. Diagnosis was made by clinical findings and investigation about the working environment. RESULTS: 1. The most common dermatoses are contact dermatitis(14.3%), acne(14.0%), seborrheic dermatitis(7.1%) and tinea pedis(6.9%). Urticaria, hand eczerna, abscess, onychomycosis, t.inea versicol or and chemical burn were also observed frequently. 2. Chemical burn(2.0%), contact dermatitis(1.4%) and acne(0.8%) were the most important occupation related dermatoses in this survey. Hydrofluoric acid(1.4%) was the main cause of chemical burn. The occupationa contact dermatitis and acne in this survey were mainly came from the mask, hood and dust preventing clothes which the workers must wear for 8 hours a day at working place. 3. The other dermatoses related to occupation were hand eczema, trauma, nummular eczema, atopic dermatitis, etc.. CONCLUSION: This study regardless of insufficient inspection equipment was done for a relatively long period in the semiconductor industry. In the future, many studies like this will be reported and the studies will give a model of management of occupational dermatoses in Korea.
Abscess ; Acne Vulgaris ; Burns, Chemical ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Diagnosis ; Dust ; Eczema ; Female ; Hand ; Humans ; Korea ; Masks ; Occupations ; Onychomycosis ; Semiconductors* ; Skin Diseases* ; Tinea ; Urticaria

STUDY DESIGN: Case report. OBJECTIVES: To report a case of cerebellar tumor mimicking cervical spinal disease with neck pain for one year. SUMMARY OF LITERATURE REVIEW: Neck pain is one of the most common symptoms of cervical spinal disease. Neck pain in the cervical spine is usually accompanied by radiculopathic or myelopathic symptoms. Pain aggravated with neck motion is another point of differentiation. However, the differential diagnosis of neck pain is not always easy. MATERIALS AND METHODS: A 47-year-old woman presented with neck pain, without other symptoms of radiculopathy or myelopathy. The neck pain was not position-dependent and had exacerbated 1 week previously. Cervical magnetic resonance imaging (MRI) revealed a brain tumor in the cerebellum. RESULTS: The patient underwent surgical craniotomy and tumor resection. The neck pain improved after surgery. CONCLUSIONS: If neck pain cannot be explained by cervical pathological conditions, the possibility of other causes, including brain pathology, should be considered.
Brain Diseases ; Brain Neoplasms* ; Brain* ; Cerebellar Neoplasms ; Cerebellum ; Craniotomy ; Diagnosis, Differential ; Female ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neck ; Neck Pain ; Radiculopathy ; Spinal Cord Diseases ; Spinal Diseases* ; Spine