1.A Case of Conjunctival Intraepithelial Neoplasia(CIN) Misdiagnosed as Atypical Pterygium.
Do Hyung LEE ; Jeung Hun JANG ; Jae Yoon OH ; Jae Suk KIM
Journal of the Korean Ophthalmological Society 2000;41(12):2750-2754
No Abstract Available.
Pterygium*
2.Effect of metabolic shock induced by 2-deoxy-D-glucose on the murine immune response.
Yang Suk KIM ; Seon Il JANG ; Shee Eun LEE ; Bok Soo LEE ; Hun Taeg CHUNG
Korean Journal of Immunology 1993;15(1):37-43
No abstract available.
Deoxyglucose*
;
Shock*
3.Microcystic Meningioma: Case Report.
Hyeun Sung KIM ; Suk Jung JANG ; Seong Hun JEONG
Journal of Korean Neurosurgical Society 1998;27(9):1271-1276
Microcystic meningioma, a distinct morphological variant of meningiomas, is histologically characterized by a vacuolated appearance with multiple cystic spaces lined by vacuolated or stellate-shaped tumor cells. This unusual variant was originally described by Masson, who labeled it "humid". The clinical and morphological findings point toward a benign course. And these unusual morphological variants of meningioma are potentially curable tumor. But there is no definitive method for preoperatively differentiating microcystic meningioma from the malignant glioma. We report a case of microcystic meningioma occurring in the left frontal area of 74 year old woman, with malignant clinical nature.
Aged
;
Female
;
Glioma
;
Humans
;
Meningioma*
4.Partial Pediculectomy for Spondylolisthesis with Radicular Pain Combined with Severe Osteoporosis.
Myoung Jin PARK ; Ho SHIN ; Ha Young CHO ; Seung Myoung LEE ; Seong Hun JEONG ; Jin Kyu SONG ; Suk Jung JANG
Journal of Korean Neurosurgical Society 2000;29(1):51-57
No abstract available.
Osteoporosis*
;
Spondylolisthesis*
5.Analysis for Circumstantial Factors in Onset of Subarachnoid Hemorrhage.
Hyeun Sung KIM ; Suk Jung JANG ; Seong Hun JEONG
Journal of Korean Neurosurgical Society 1998;27(7):939-946
Seasonal and climatic variations have been linked to the occurrence of some types of cerebrovascular disease. However, the conditions that lead to intracranial aneurysm rupture are not known. The purpose of the present study was to determine whether predisposing factors are more related to intracranial aneurysm rupture and to determine relation of the stressful condition to intracranial aneurysm rupture. In order to determine the predisposing factors, the authors have examined the relationship between seasonal variation and predisposing factors of cerebral aneurysm. The author investigated activities of the patients and events as well as diurnal and seasonal variations in the onset of subarachnoid hemorrhage(SAH) in 336 consecutive patients. The results showed that the onset of SAH was associated with working in 11.0%, defecation and/or urination in 8.3%, sleeping in 6.9% and 4.2% walking. Hypertensive patients in aneurysmal rupture was 36.0%. Subarachnoid hemorrhage occurred during stressful events in 36.3% of the patients, during nonstreneous events in 34.8% and during rest or sleep in 9.8%. The activities or events preceding subarachnoid hemorrhage were not known in the remaining 18.8%. Men were more likely to have suffered their hemorrhages during stressful events than women(47% vs 30%). Peak times of intracranial aneurysm rupture usually occurred from 6 to 11 A.M.(36.0%) and from 4 to 6 P.M.(20.5%). The seasonal variation of the onset of SAH showed the incidence to be slightly higher in winter than in any other seasons. We concluded that the occurrence of subarachnoid hemorrhage display seasonal and diurnal variation. And the precipitation of aneurysmal rupture have two important factors; increased arterial blood pressure and decreased cerebrospinal fluid pressure around the aneurysm. Also, the onset of the subarachnoid hemorrhage is related to the physiological circadian periodicity of blood pressure, climatic change and stressful events.
Aneurysm
;
Arterial Pressure
;
Blood Pressure
;
Causality
;
Cerebrospinal Fluid Pressure
;
Defecation
;
Hemorrhage
;
Humans
;
Incidence
;
Intracranial Aneurysm
;
Life Change Events
;
Male
;
Periodicity
;
Rupture
;
Seasons
;
Subarachnoid Hemorrhage*
;
Urination
;
Walking
6.Effect of the Mixture of Thrombin Powder and Gelfoam Powder on Control of Exposed Cancellous Bone Bleeding.
Sung Wan PARK ; Ha Young CHO ; Seung Myoung LEE ; Seong Hun JEONG ; Jin Kyu SONG ; Suk Jung JANG ; Ho SHIN
Journal of Korean Neurosurgical Society 2000;29(5):664-667
No abstract available.
Gelatin Sponge, Absorbable*
;
Hemorrhage*
;
Thrombin*
7.Urinary NMP22 and BTA tests as screening markers for bladder transitional cell carcinoma.
Soo Youn LEE ; Eun Suk KANG ; Ki Sook HONG ; Bong Suk SHIM ; Ok Kyoung KIM ; Hae Soo KU ; Jung Soo LEE ; Suk Hun JANG
Korean Journal of Clinical Pathology 2000;20(4):372-378
BACKGROUND: Urinary bladder cancer has been diagnosed by urine cytology and cystoscopy with biopsy. Recently, in vitro noninvasive diagnostic tests, measuring urinary nuclear matrix protein22(NMP22) and bladder tumor antigen(BTA), were introduced. We analyzed the usefulness of the NMP22 and BTA tests for diagnosing bladder cancer and compared those with voided urine cytology. MATERIALS AND METHODS: Single voided urine specimens were obtained from 27 patients with bladder cancer and 23 healthy volunteers. The urine specimens were assayed by enzyme immunoassay(NMP22, Matrietech(R), Newton, MA.) and latex immunoassay(BTA, Bard, USA). Urine cytology was performed in patients with bladder cancer. RESULTS: Mean urinary NMP22 level of patients with bladder cancer(144.6 U/mL) was significantly higher than those of normal controls(2.9 U/mL, P<0.01). The sensitivities were 89% and 74% for NMP22 and BTA tests, respectively, compared with 41% for voided urine cytology. The sensitivities of NMP22 and BTA tests were 88%, 63% at grade 1(G1), 82%, 73% at G2, and 100%, 88% at G3, respectively(P<0.01; NMP22, P=0.580; BTA). According to tumor stage, the sensitivities of NMP22 and BTA tests were both 79% at superficial, and 100% and 69% at invasive cancer, respectively(P=0.110; NMP22, P=0.678; BTA). The sensitivities of urine NMP22 and BTA tests combined with urine cytology were both 96%. In following of transitional cell carcinoma patients, agreement between urine cytology and BTA test was 75%(24/32). Among the various urologic disease, false positive rate for BTA test was 17%(8/47). CONCLUSION: Urinary NMP22 and BTA tests were more sensitive than voided urine cytology regardless of tumor grade and stage, so these noninvasive and simple tests can be used as screening tests for urinary bladder transitional cell carcinoma.
Biopsy
;
Carcinoma, Transitional Cell*
;
Cystoscopy
;
Diagnostic Tests, Routine
;
Healthy Volunteers
;
Humans
;
Latex
;
Mass Screening*
;
Nuclear Matrix
;
Urinary Bladder Neoplasms
;
Urinary Bladder*
;
Urologic Diseases
8.A case of cytomegalovirus colitis in immunocompetent patient.
Kyung Ha SONG ; Jong Hun LEE ; Jin Suk JANG ; Sung Hun MUN ; Se Jun JANG ; Myung Hwan RHO ; Sang Young HAN ; Suk Lyul CHOI ; Woo Won SHIN ; Tae Ho PARK ; Moo Hyun KIM ; Mee Suk RHO ; Kyung Hee KIM
Korean Journal of Medicine 2002;62(2):218-222
Cytomegalovirus (CMV) infection is more frequent in immunocompromised patients those with acquired immunodeficiency syndrome (AIDS), malignant disease, steroid therapy. However, CMV can infect a healthy person who has normal immunity. Most cases of CMV infections are due to reactivation of latent virus. We report a case of cytomegalovirus colitis in a 73 years old woman who has congestive heart failure with normal immunity. Sigmidoscopy reveals cobble stone like mucosa and deep ulceration. CMV infection produces a cytomegalic cell containing a intranuclear inclusion, which is surrounded by clear halo in Hematoxylin-Eosin stain. Immunohistochemical stain for CMV reveals focal positive in cytoplasm and in nuclei of large cells. We diagnosed CMV colitis with histopathologic finding and immunohistochemistry through sigmoidoscopic mucosal biopsy.
Acquired Immunodeficiency Syndrome
;
Aged
;
Biopsy
;
Colitis*
;
Cytomegalovirus*
;
Cytoplasm
;
Female
;
Heart Failure
;
Humans
;
Immunocompromised Host
;
Immunohistochemistry
;
Intranuclear Inclusion Bodies
;
Mucous Membrane
;
Ulcer
9.Acoustic Rhinometry in Nasal Provocation Test.
Tae Young JANG ; Yeong Seok YUN ; Dong Hak JUNG ; Byung Hun KIM ; Young Jin KIM ; Weon Suk CHOI
Journal of Rhinology 1997;4(2):116-119
A nasal provocation test is the most reliable diagnostic test to confirm allergen in allergic rhinitis. However, there are neither specific objective methods nor a standardized method and interpretation. In 20 normal subjects and 86 allergic rhinitis patients, we applied acoustic rhinometry as a new objective method to assess changes in nasal patency induced by nasal allergen challenge, a procedure which is used for confirming allergic rhinitis. The result shows that a minimal cross-sectional area (MCA) and volume from the nose tip on back to 7 cm (nasal cavity volume) after allergen challenge were significantly decreased in allergic rhinitis patients in comparison with the control subjects. We conclude that acoustic rhinometry can provide a sensitive index for evaluating the results of a nasal provocation test.
Acoustics*
;
Diagnostic Tests, Routine
;
Humans
;
Nasal Provocation Tests*
;
Nose
;
Rhinitis
;
Rhinometry, Acoustic*
10.The Early Change of Posterior Corneal Sureace after LASIK Sugery.
Jeung Hun JANG ; Jae Suk KIM ; Do Hyung LEE
Journal of the Korean Ophthalmological Society 2002;43(12):2401-2406
PURPOSE: To evaluate posterior corneal surface elevation after LASIK in relation to the residual stromal bed thickness and the ablation percentage. METHODS: 363 eyes that underwent LASIK were examined retrospectively. The range of their refractive error was from -1.5 to -10.0 D. We obtained their corneal topography with Orbscan II and pachymetry preoperatively, and at one week, one month, two months, and three months postoperatively. The patients were divided into four groups based on the residual stromal bed thickness: Group I; 145 eyes with less than 250 micrometer, Group II; 129 eyes with 250~300 micrometer, Group III; 79 eyes with 300~350 micrometer, and Group IV; 13 eyes with more than 350 micrometer. We also grouped them based on the ablation percentage per total corneal thickness: Group A; 16 eyes with less than 10%, Group B; 166 eyes with 10~15%, Group C; 149 eyes with 15~25%, and Group D; 35 eyes with more than 25%. RESULTS: The extent of increase in the post-LASIK posterior corneal surface elevation correlates with residual corneal bed thickness and the ablation ratio per total cornea. In contrast, posterior corneal elevation values for Group IV were 0.025+/-0.005 mm preoperatively, 0.038+/-0.007 mm at 1 weeks, 0.037+/-0.010 mm at 1 month, 0.03+/-6 0.012 mm at 2 months, 0.036+/-0.009 mm at 3 months. In Group A, the values at the same times were 0.029+/-0.009 mm, 0.043+/-0.012 mm, 0.039+/-0.013 mm, 0.040+/-0.013 mm, 0.038+/-0.010 mm. CONCLUSIONS: The extent of increase in the post-LASIK posterior corneal surface elevation correlates with residual corneal bed thickness and the ablation ratio. There were no statistically significant changes in postsurgical posterior corneal surface elevation, however, if the residual corneal thickness remained more than 350 micrometer or the ablation percentage was lower than 10%.
Cornea
;
Corneal Topography
;
Humans
;
Keratomileusis, Laser In Situ*
;
Refractive Errors
;
Retrospective Studies