No abstract available.
Primary Myelofibrosis*

Actinomycosis is an oppoturnistic infection of actinomyces, which are relatively avirulent endogenous oral commensals. After trauma or infection, they breach the normally protective mucosal barriers to invade adjacent soft tissue structures. Lesions routinely contain other bacteria, the normal resident flora at the site of primary infection, which act synergistically with actinomyces species to provoke this unique infection, which range from an acute suppurative process to a chronic fibrotic process. According to epidemic studies about pelvic actinomycosis, it should be significantly related to IUD(intrauterine device). It is accounted that IUD cause chronic intrauterine infection, tissue injury and act as nucleus for parasitic infestation. Here we present a case of pelvic actinomycosis related to IUD with brief review of the concerned literature.
Actinomyces ; Actinomycosis* ; Bacteria

Hemorrhagic complications associated with aspirin use occur primarily at skin or gastrointestinal sites but can occasionally occur in the central nervous system. In particular, spontaneous spinal epidural hemorrhage (SSEH) associated with aspirin is very rare. We report a case of low-dose (100 mg daily) aspirin-related SSEH that was successfully treated with medical management. Our case indicates that low-dose aspirin could induce SSEH and that conservative treatment with close observation and repeated imaging studies should be considered in cases with neurological improvement or mild deficits.
Aspirin ; Central Nervous System ; Hematoma ; Hematoma, Epidural, Spinal ; Skin

No abstract available.
Lung* ; Pneumonia*

Subdural empyema is a fulminating, purulent, bacterial infection located between the dura and arachnoidal membrane. Early diagnosis, adequate antibiotic therapy and surgical treatment played important roles in the successful management of subdural empyema. Subdural empyema can develop secondary to sinusitis, otitis media, meningitis, trauma or craniotomy. Subdural empyema in infants commonly develops secondary to infected subdural effusion associated with purulent meningitis. The incidence of this complication of meningitis in infants is approximately 2%. We report a case of subdural empyema concomitant with bilateral subdural effusion, which was successfully treated with surgical intervention and antibiotic therapy.
Arachnoid ; Bacterial Infections ; Craniotomy ; Early Diagnosis ; Empyema, Subdural* ; Humans ; Incidence ; Infant* ; Membranes ; Meningitis* ; Otitis Media ; Sinusitis ; Subdural Effusion*

No abstract available.
HL-60 Cells* ; Humans

No abstract available.
Kidney Transplantation*

No abstract available.
Appendix* ; Fetus*

The variations of the occipital sinus were studied in 50 Korean adult cadavers. The morphology of the sinus was classified into 5 types accordingo to its number and the connection with the marginal sinus. These results were compared with the data of the occipital sinus of bones (Sir and Chung, 1907). And the opening of the occipital sinus in the confluens sinuum was observed. 1. A single small occipital sinus was found in 40%. Single occiital sinus with two large marginal sinuses was observed in 8%. The single sinus with a left marginal sinus (6%) and with a right marginal sinus(4%) were present. Double occipital sinuses were observed in 10% of the cadavers. No occipital sinus was discernible in 32%. 2. There were 39 openings of the occipital sinus including the double sinuses. The occipital sinuses communicated with the confluence sinuum in 35 cases (89.7%), with the straight sinus in 5.1% and with the right or left transverse sinus in 1 case, respectively. The openings in the confluens sinuum were found on the left side(51.3%), on the right side (10.3%) and in the center(28.2%). 3. The diameters of the occipital sinus were variable according to the connection with the sigmoid sinus. 4. The difference was found between the data of the morphological types of the occipital sinus that were studied in cadavers and in dry bones.
Adult* ; Cadaver ; Colon, Sigmoid ; Humans

BACKGROUND: Ultraviolet B (UVB) radiation is a major harmful environmental factor causing cutaneous changes such as sunburn, skin aging and skin cancer. Excessive UVB irradiation induces apoptosis of keratinocytes through several molecular pathways. However, the precise molecular mechanisms have been underinvestigated. OBJECTIVE: The purpose of this study was to investigate expression levels of apoptosis-related genes in UVB- irradiated HaCaT ketratinocyte cell lines. METHODS: Cells were irradiated by UVB at various doses (0, 100, 200 and 400 mJ/cm2). Expression levels of caspases, Bax, Bcl2, and Bcl-XL were confirmed by RT-PCR analysis and western blotting. RESULTS: Expression of cytochrome C was increased followed by activation of caspase-3, 8 and 9 in UVB-irradiated HaCaT cells. Furthermore, the expression of Bcl-XL was decreased from UVB 200 mJ/cm2 and Bcl2 was decreased weakly from UVB 400 mJ/cm2, implying that the expression of Bcl-XL is more sensitive to UVB. Interestingly, the down-regulation of Bcl-XL may be mediated by proteasome dependent pathways. CONCLUSION: Excessive UVB-irradiated HaCaT cells undergo apoptotic cell death following activation of caspases; degradation of Bcl-XL is particularly sensitive to UVB.
Apoptosis ; Caspase 3 ; Caspases ; Cell Death ; Cytochromes c ; Down-Regulation ; Keratinocytes ; Proteasome Endopeptidase Complex ; Skin Aging ; Skin Neoplasms ; Sunburn