Authors performed the chordectomy using Blair, Byars and Glenn-Anderson method, the urethroplasty with Denis-Browne-Crawford method and one-stage repair of hypospadia with Allen-Spence method. The following results are obtained from 40 cases of urethroplasty and 10 cases of one-stage repair of hypospadia which were done in the Department of Urology, Busan National Univ. Hospital during recent 7 yrs (71~77). The results were as follows : 1. The most common age group of hypospadia was observed in 11-20 year old (40.0 %) and that of less than 5 year old was only 12.0 %. 2. The most common type of hypospadia was observed in ponoscrotal type (26.0 %) while the hypospadia without chordee was 2.0 %. 3. The most common anomaly associated with hypospadia was cryptorchism (40.0 %). 4. Average of the period of postoperative hospitalization was 9.5 days in chordectomy. 10.8 days in urethroplasty and 10.2 days in one-stage repair of hypospadia. The interval between chordectomy and urethroplasty was 13.9 months. 5. Average of the period of postoperative urethral catheterization was 7.6 days in chordectomy, 3.2 days in urethroplasty and 7.5 days in one-stage repair of hypospadia. 6. The postoperative complications were 2 cases of persistent chordee in Blair method, 1 case of fistula and 3 cases of stricture in Denis-Drowne-Crawford urethroplasty and 2 cases of fistula in one-stage repair of hypospadia. The success rate was 91.9 % in Blair method. 100 % in Byars method and Glenn-Anderson method, 90.0 % in Denis-Browne-Crawford urethroplasty and 80.0 % in one stage repair of hypospadia.
Busan ; Child, Preschool ; Constriction, Pathologic ; Cryptorchidism ; Female ; Fistula ; Hospitalization ; Humans ; Hypospadias* ; Male ; Postoperative Complications ; Urinary Catheterization ; Urinary Catheters ; Urology

In this investigation, the bladder of guinea pig was longitudinally mounted in the muscle chamber and contracted by electrical field stimulation(EFS). It was purposed to elucidate the physiological significance of prostaglandin(PG) on the neurotransmitter release from nerve ending. 1. The inhibitory response of 5 x 0.0000001 g/ml atropine was significant only by high frequency (p<0.05) However. the curve of frequency-response were shifted to left upward by 5 x 0.00000001 g/ml phentolamine, it were not significant. Because the contraction was completely abolished by 0.00000001 and 0.0000001g/ml tetrodotoxin, it was evident that the responses to electrical stimulation are entirely due to nerve mediated excitation. 2. The curve of frequency-response were significantly shifted to left upward by 5x 0.00000001 and 5x0.0000001 g/ml arachidonic acid(p<0.05). Though the contraction were inhibited by 5x0.0000001g/ml atropine it was not significant. 3. The curves of frequency-response showed dose-response relation by 5x 0.00000001, 5 x0.000000001 and 5x 0.0000000001g/ml PGE2. The contraction was significant only by high frequency in 5x0.0000000001g/ml PGE. and the frequency-response curves were significant in varying frequencies in 5x0.000000001and 5x0.00000001g/ml PGE2(p<0.05). 4. Although the contraction was found by 5x0.0001g/ml aspirin, the curves of frequency-response were not significant. The contraction by 5x 0.0001g/ml aspirin and 5x0.000001/ml arachidonic acid was not significant too.
Animals ; Arachidonic Acid ; Aspirin ; Atropine ; Dinoprostone ; Electric Stimulation ; Guinea Pigs ; Nerve Endings ; Neurotransmitter Agents ; Phentolamine ; Prostaglandins E ; Tetrodotoxin ; Urinary Bladder

The authors carried out the cystoplasty by regeneration to a 24 year-old female of tuberculous contracted bladder with artificial bladder. The artificial bladder was prepared by using nobecutane-sprayed paper, which was designed by repetition of Nobecutane spraying and drying. The artificial bladder was subjected to a crucial incision on the dome and a No. 10 porous catheter was inserted from the urethra into the bladder. The artificial bladder was sutured with the original incised one with a margin of 1 Cm using 3-0 chromic catgut. The authors observed for 2 months postoperatively. The following results were obtained. 1. The artificial bladder fell off completely in the bladder in 34 days after the cystoplasty, which was extirpated transurethrally. 2. The bladder capacity was about 30 cc before the operation. Following the cystoplasty, it increased up to 180-220 cc by the 50th postoperative day, and the frequency of urination was 8 times in day and 3 times in night.
Catgut ; Catheters ; Female ; Humans ; Regeneration ; Thiram ; Urethra ; Urinary Bladder* ; Urination ; Young Adult

Three cases or urethral diverticulum in the female, one of which is complicated by stone formation, were reported. Although these patients were diagnosed by routine physical examination, further postvoiding films and endosopy studies indicated to know accurate size, location, extension and contents of the diverticulum. The transvaginal diverticulectomy was performed and postoperative complications did not arise.
Diverticulum* ; Female* ; Humans ; Physical Examination ; Postoperative Complications

A case of leiomyoma of the urinary bladder in a 50 year-old woman was reported. The mass covered with normal bladder mucosa was found on the right lateral wall of bladder by cystoscopic examination. The tumor weighing 27 gm. remored through transyesical approach was leiomyoma of bladder wall. The bladder mucosa was within normal limits and no signs of metastasis were noticed 10 months after surgery.
Female ; Humans ; Leiomyoma* ; Middle Aged ; Mucous Membrane ; Neoplasm Metastasis ; Urinary Bladder*

Central pontine myelinolysis (CPM) by complicating rapid correction of severe hyponatremia has been widely reported. Additionally, CPM was occasionally reported among patients with post-liver transplantation, burns, chronic renal failure with dialysis, or other diseases associated with or not associated with other electrolyte changes or hyperosmolarity. However, there have been a few reports of CPM occurring in diabetic patients without documented electrolyte changes. This report is, to the best of our knowledge, the first report of CPM in type 2 diabetic patients without electrolyte changes in Korea. A 40-year-old man with type 2 diabetes mellitus with abruptly developed dysarthria and ataxia was admitted to our facility. He suffered from poor glucose control and multiple diabetic complications. Brain magnetic resonance imaging (MRI) revealed a well-defined bilateral symmetric hyperintense lesion in the central portion of the pons on T2- and diffusion-weighted images, which was consistent with CPM. After the patient's blood glucose and blood pressure normalized, his dysarthria and ataxia improved. Six months after discharge, follow-up MRI showed a persistent, but greatly reduced symmetric lesion in the central pons. It is certainly possible for CPM to be overlooked clinically in diabetic patients, but more cases could be diagnosed if careful attention was paid to this syndrome.
Adult ; Ataxia ; Blood Glucose ; Blood Pressure ; Brain ; Burns ; Diabetes Complications ; Diabetes Mellitus, Type 2 ; Dialysis ; Dysarthria ; Follow-Up Studies ; Glucose ; Humans ; Hyponatremia ; Kidney Failure, Chronic ; Korea ; Magnetic Resonance Imaging ; Myelinolysis, Central Pontine ; Pons ; Transplants

Serotonin syndrome, an adverse drug reaction, is a consequence of excess serotonergic agonism of central nervous system receptors and peripheral serotonergic receptors. Serotonin syndrome has been associated with large numbers of drugs and drug combinations, and serotonin-norepinephrine reuptake inhibitor-induced serotonin syndrome is rare. It is often described as a sign of excess serotonin ranging from tremor in mild cases to delirium, neuromuscular rigidity, and hyperthermia in life-threatening cases. Diagnosis is based on the symptoms and patient's history, and several diagnostic criteria have been developed. We experienced a rare case of fibromyalgia accompanied by tremor, hyperreflexia, spontaneous clonus, muscle rigidity, and diaphoresis after 10 days of single use of duloxetine 30 mg. Only one case of serotonin syndrome resulting from administration of duloxetine has been reported in Korea, however that case resulted from co-administration of fluoxetine. We report here on this case along with a review of the relevant literature.
Central Nervous System ; Delirium ; Diagnosis ; Drug Combinations ; Drug-Related Side Effects and Adverse Reactions ; Duloxetine Hydrochloride* ; Felodipine ; Fever ; Fibromyalgia* ; Fluoxetine ; Humans ; Korea ; Muscle Rigidity ; Reflex, Abnormal ; Serotonin Syndrome* ; Serotonin* ; Tremor