Observations were made by viewing 563 syphilics that were diagnos d and treated in the Department of Dermatology at Chon-nam University Hospital, for ten con- secutive years(1968 1977). During this ten-year period, the average percent of syphilitic cases seen was l. 72 of the yearly total outpatients. The yearly number of patients seen during this study period showed no consistent pattern of increase, however, there were particularly large numbers of patients seen in the last few years of the study, this indicating an increase in the trend of syphilis in our area. The large number of latent syphilitic cases (56. 3Y) seen, paticularly in the early latent stage, was reflected in total numbers as being of the greatest percentile And the ratio of early latent cases to primary and secondary cases averaged out to 1. 1: l during the ten-year period In 23. 2 percent of 190 women of child bearing age, pregnancies were terminated ly abortion or stillbirth. Of all cases, 9. 9 percent had other STDs in which the most frequent was scabies. As a follow up only 85 patients (15. 1Pl) underwent serial quantitative evaluation for 12 months or more, 6 of these patients (7M) were identified as serorelapse cases who should be retreated.
Child ; Dermatology ; Evaluation Studies as Topic ; Female ; Follow-Up Studies ; Humans ; Outpatients ; Pregnancy ; Scabies ; Sexually Transmitted Diseases ; Stillbirth ; Syphilis*

Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january, 1991 to March, 1991. The results were as follows; 1) Of the 149 patients, influenza virus were isolated in the 15 cases. 15 isolates were characterized by the WHO Collaborating Center for influenza: 7 cases were very similar to influenza A/Taiwan/1/86 (H1N1), 1 case was A/Beijing/353/89 (H3N2), 7 cases were B/Guangdon-g/55/89. 2) The age of 15 patients who were confirmed by viral isolation was between 11 months to 10 years. 3) The most common clinical symptoms were fever, vomiting, cough, nausea in deceasing order. 4) Of the total 149 patients, Reye syndrome occured in two patients and myositis occured in one: Influenza A/Taiwan/1/86 (H1N1) virus was isolated in one Reye syndrome patient.
Chungcheongnam-do ; Cough ; Fever ; Humans ; Influenza, Human* ; Myositis ; Nausea ; Orthomyxoviridae ; Pediatrics ; Reye Syndrome ; Seoul* ; Vomiting

BACKGROUND: Helicobacter pylori increases production of reactive oxygen species (ROS), which activates inflammatory and carcinogenesis-related signaling pathways in gastric epithelial cells. Therefore, reducing ROS, by upregulating antioxidant enzyme, such as superoxide dismutase (SOD), may be a novel strategy to prevent H. pylori-associated gastric diseases. Astaxanthin is an antioxidant carotenoid that prevents oxidative stress-induced cell injury. The present study was aimed to determine whether H. pylori decreases SOD activity by changing the levels of SOD1/SOD2 and whether astaxanthin prevents changes in SOD levels and activity in H. pylori-infected gastric epithelial AGS cells. METHODS: AGS cells were pre-treated with astaxanthin for 3 hours prior to H. pylori infection and cultured for 1 hour in the presence of H. pylori. SOD levels and activity were assessed by Western blot analysis and a commercial assay kit, respectively. Mitochondrial ROS was determined using MitoSOX fluorescence. RESULTS: H. pylori decreased SOD activity and the SOD2 level, but increased mitochondrial ROS in AGS cells. The SOD1 level was not changed by H. pylori infection. Astaxanthin prevented H. pylori-induced decreases in the SOD2 level and SOD activity and reduced mitochondrial ROS in AGS cells. CONCLUSIONS: Consumption of astaxanthin-rich food may prevent the development of H. pylori-associated gastric disorders by suppressing mitochondrial oxidative stress.
Blotting, Western ; Epithelial Cells ; Fluorescence ; Helicobacter pylori ; Helicobacter ; Oxidative Stress ; Reactive Oxygen Species ; Stomach Diseases ; Superoxide Dismutase ; Superoxides