1.Overview of Roles for Non-cardiac Natriuretic Peptides: Roles in Neural, Endocrine and Immune Systmes.
Kyung Woo CHO ; Suhn Hee KIM ; Sung Joo KIM
Journal of Korean Society of Endocrinology 2000;15(6):760-778
No Abstract Available.
Natriuretic Peptides*
2.Renal and hormonal effects of lithium chloride.
Nam Jin PARK ; Suhn Hee KIM ; Kyung Woo CHO
Journal of Korean Society of Endocrinology 1992;7(3):251-259
No abstract available.
Lithium Chloride*
;
Lithium*
4.Nephron heterogeneity of renin release in spontaneously hypetensive rats.
Young Jin CHOI ; Suhn Hee KIM ; Une KIM ; Kyung Woo CHO
Journal of Korean Society of Endocrinology 1991;6(4):314-319
No abstract available.
Animals
;
Nephrons*
;
Population Characteristics*
;
Rats*
;
Renin*
5.Effects of chronic cold exposure on renal function and atrial natriuretic peptide content.
Hyang KIM ; Chang Won KANG ; Sang Hun HAN ; Suhn Hee KIM ; Kyung Woo CHO
Journal of Korean Society of Endocrinology 1993;8(2):134-140
No abstract available.
7.Nephron heterogeneity in response to TMB-S in spontaneouslyhypertensive rats.
Sung Jin KIM ; Kyung Hwan SEUL ; Kyung Woo CHO ; Suhn Hee KIM ; Dong Soo PARK
Journal of Korean Society of Endocrinology 1992;7(3):260-266
No abstract available.
Animals
;
Nephrons*
;
Population Characteristics*
;
Rats*
8.Effect of adenosine analogues on the plasma renin concentration in spontaneously hypertensive rats.
In Soon PARK ; Chang Won KANG ; Suhn Hee KIM ; Kyung Woo CHO
Journal of Korean Society of Endocrinology 1993;8(1):42-50
No abstract available.
Adenosine*
;
Plasma*
;
Rats, Inbred SHR*
;
Renin*
9.Roles of Calcium in Regulation of ANP Secretion.
Kyung Woo CHO ; Wen Jin FU ; Jin HUA ; Suhn Hee KIM
Korean Journal of Nephrology 2001;20(5):737-748
No abstract available.
10.Effects of angiotensin peptides on colonic motility in rats
Gi Won HA ; Jong Hun KIM ; Suhn Hee KIM
Annals of Coloproctology 2023;39(3):267-274
Purpose:
Renin-angiotensin system (RAS) is involved in the pathophysiology of colonic inflammation. The aim of this study was to investigate whether small angiotensins (Angs) peptides play a role in the regulation of colonic motility and their roles are modulated in colitis.
Methods:
Experimental colitis was induced by an intake of 5% dextran sulfate sodium (DSS) dissolved in tap water for 7 days in Sprague-Dawley rats. After sacrifice, plasma hormone concentrations and messenger RNAs (mRNAs) for RAS were measured. Functional analysis of colonic motility in response to Angs peptides was performed using Taenia coli.
Results:
DSS-treated colon showed an increased necrosis with massive infiltration of inflammatory cells. The mRNA level of colonic angiotensin II receptor type 2 (AT2R) in DSS-treated rats was higher than that in control rats whereas the mRNA levels of angiotensin II converting enzyme (ACE), ACE2, AT1R, AT4R, and Mars receptor were not different from those in control rats. Ang III, Ang IV, and Ang-(1-9) (1, 3 μM) increased the frequency of basal colonic motility. Ang-(1-7) did not cause any significant changes in frequency and amplitude of basal motility. The order of potency for an increased frequency of basal motility seems to be Ang II>>Ang IV>Ang III=Ang-(1-9). The increased frequency of basal motility by Ang-(1-9) but not Ang IV was significantly enhanced in DSS-treated rat colon.
Conclusion
In conclusion, these data suggest that small Angs peptides are partly involved in the pathophysiological regulation of colonic motility in experimental colitis.
Result Analysis
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