OBJECTIVE:To observe clinical efficacy and ADR of Houttuynia cordata eye drops combined with Olopatadine eye drops in the treatment of allergic conjunctivitis. METHODS:160 eyes with allergic conjunctivitis were randomly divided into observation group and control group,with 80 eyes in each group. The control group was given olopatadine eye drops,and observa-tion group was additionally given H. cordata eye drops(medication interval>10 min)on the basis of control group. Both groups were treated for 14 days. Symptoms and signs of 2 groups were observed and scored before treatment and 14 d after treatment. Ef-fective rates of 2 groups were calculated,and the occurrance of ADR was observed. RESULTS:Compared with before treatment, symptoms and sings score of 2 groups were decreased,with statistical significance (P<0.01 or P<0.05);the decrease of two score in observation group were more significant than in control group,with statistical significance (P<0.05);effective rates of control group and observation group were 37.50%and 77.50%,with statistical significance(P<0.05). CONCLUSIONS:H. corda-ta eye drops combined with olopatadine eye drops can ameliorate clinical symptoms and signs of allergic conjunctivitis patients sig-nificantly,and improve therapeutic efficacies without obvious ADR.

Objective:To investigate the effect of upper limb pillow position on hemodynamic and safety of patients undergoing cerebellopontine angle tumor resection.Methods:Eighty-four patients receiving cerebellopontine angle tumor resection in our hospital from January 2016 to December 2019 were randomly divided into the experimental group (42 cases) and the control group (42 cases). Patients in the control group were placed in routine upper limb position, while patients in the experimental group were placed in upper limb pillow position. The data including systolic pressure, diastolic pressure, heart rate, saturation of blood oxygen were recorded on admission of operation room, completing placing body position, 30 minutes and 60 minutes after operation and after finishing the operation. The numbness/soreness of upper limbs and pressure injury rate was compared between the experimental group and the control group.Results:The rate of numbness/soreness of upper limbs were 2.4% (1/42) in the experimental group, 19.1%(8/42) in the control group, the differences were statistically significant ( χ2 value was 6.098, P<0.05). The stage 1 pressure injury were 2 cases in the experimental group, stage 1 and 2 pressure injury were 6 cases and 2 cases, respectively in the control group, the differences were statically significant ( Z value was 2.039, P<0.05). Conclusion:Upper limb pillow position of the operation side can reduce postoperative complication of patients undergoing cerebellopontine angle tumor resection, but will not increase the risk of abnormal hemodynamic fluctuation.

Objective To evaluate the clinical effect of endoscopic sphineterotomy (EST) and endoscopic sphincterotomy associated with traditional Chinese medicine in the treatment of intrahepafic duct stones.Methods Eighty patients with common bile duet stones and intrahepatic duct stone were randomly divided into a treatment group and a control group.EST associated with traditional Chinese medicine was performed in the treatment group,and EST only was used in the control group.Clinical effects were observed.Results Common bile Duet stone clearance was achieved in 94% patients in the treatment group,contrasting 88% in the control group.There was no significant difference between them (P＞0.05).While intrahepatic duct stone clearance was 74% and 28% respectively in the treatment group and the control group,showing significant difference (P＜0.05).Conclusion It is a good way that endoscopic sphincterotomy associated with traditional Chinese medicine treating intrahepatic duct stones.

Objective To investigate the clinical value of PCR method for rapid screening Salmonella/Shigella in health physical examination .Methods A total of 3256 cases who were taken health physical examination from July 2011 to June 2015 ,were select-ed as the research object .Real-time fluorescence quantitative PCR method and the culture method were used for detecting Salmonel-la/Shigella ,and two methods were compared on their strengths and weaknesses for screening Salmonella/Shigella .Results A total of 46 cases with Salmonella were detected by PCR ,and the ratio was 1 .41% ;41 cases with Salmonella were detected by traditional culture method ,and the ratio was 1 .26% .39 cases with Shigella were detected by PCR and ,the ratio was 1 .20% ;32 cases were de-tected by traditional culture method ,and the ratio was 0 .98% .The difference was statistically significant (P<0 .05) .Sensitivity and specificity of PCR to detect Salmonella were 100 .00% and 99 .84% ,respectively ,and sensitivity and specificity of PCR to detect Shigella were 100 .00% and 99 .78% ,respectively .The PCR method is better than the traditional culture method concerning man-power ,processing time ,and satisfaction of test-takers ,and the cost of PCR method is significantly higher than that of traditional culture ,with a significant difference (P<0 .05) .PCR method contains high technology and has strong objectivity .Conclusion Real time fluorescent quantitative PCR method ,with high efficiency ,can be employed well for screening intestinal tract pathogenic bacte-ria ,improve the detection rate and accuracy for detecting Shigella and Salmonella ,and save time and energy as well .