1.Efficacy of Dairy Free Diet and 6-Food Elimination Diet as Initial Therapy for Pediatric Eosinophilic Esophagitis: A Retrospective Single-Center Study
Jonathan WONG ; Sue GOODINE ; Kate SAMELA ; Katherine S VANCE ; Beth CHATFIELD ; Zhu WANG ; Wael N SAYEJ
Pediatric Gastroenterology, Hepatology & Nutrition 2020;23(1):79-88
12 weeks) were 81.8%, 50.0%, and 55.1% for DFD, and 68.8%, 50.0%, and 40.0% for SFED. Response based on age ( < 6, 6–12, and >12 years) were 59.3%, 42.9%, and 67.5% for DFD, and 36.4%, 58.8%, and 72.7% for SFED. In patients treated with DFD, concomitant proton pump inhibitor (PPI) administration resulted in improved outcomes (p=0.0177). Bivariate regression analysis showed that PPI with diet is the only predictor of response (p=0.0491), however, there were no significant predictors on multiple regression analysis.CONCLUSION: DFD and SFED are effective first line therapies for EoE. DFD should be tried first before extensive elimination diets. Concomitant therapy with PPI's may be helpful.]]>
Child
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Connecticut
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Diet
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Endoscopy
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Eosinophilic Esophagitis
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Eosinophils
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Humans
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Male
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Proton Pump Inhibitors
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Proton Pumps
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Retrospective Studies