To study plasma hemoglobin cats were given serial enemas of 0.5 and 0.25% H2O2 with human who1e blood, single enemas of 0.5% H2O2 and single intravenous administration of 0.5% H2O2. Plasma hemoglobin levels were abnormally high in both the serial enema group and the intravenous group, while the plasma hemoglobin level was within normal range in the single enema group. Therefore a single enema of 0.5% H2O2 with human whole blood can be utilized with safety clinically for 60 to 75 minutes to relieve hypoxia.
Animal ; Anoxia/drug therapy* ; Blood* ; Cats ; Comparative Study ; Enema ; Female ; Hemoglobins/analysis* ; Hydrogen Peroxide/administration & dosage* ; Hydrogen Peroxide/therapeutic use ; Injections, Intravenous ; Male