One hundred and forty-five specimens of positive bacteriology, obtained from patients admitted to the Orthopedic Department of Seoul National University Hospital during the period from January, 1970 to March, 1973, were reviewed with respect to their causative microorganisms and antibiotic sensitivity. The results were also compared with reports previously published from the same department. Following observations were made: 1. The identified microorganisms were of 9 species. Of these, the coagulase positive and negative Staphylococcus continues to be the most frequent offender occupying 62.1% of the total. 2. Of the Staphylococcus, the penicillin-resistant strains were proved in 84.6% of the series, a significant increase over the previous reports. 3. The Streptococcus, formerly the second-most frequent causative organism, occupied only 4.0% of the total suggesting a marked decrease in incidence over the last decade. 4. On the other hand, the Pseudomonas occupied 11.7% of the total when mixed infections are included and together with other Gram-negative bacilli revealed a remarkable increase in incidence during the same period.
Bacteriology ; Coagulase ; Coinfection ; Criminals ; Hand ; Humans ; Incidence ; Orthopedics ; Pseudomonas ; Seoul ; Staphylococcus ; Streptococcus

Infection is one of the most serious complications following total hip replacement arthroplasty. Many modifications of procedures have been advocated in order to reduce the rate of infection with varying success. Incorporation of antibiotic to bone cement is one such approach. However, there still remains some reluctancy to adopt this method on account of dubious antibiotic effect at the expense of weakening of physical properties. Possible emergence of resistant organisms and hypersensitivity are additional drawbacks to be considered. The present experiments were undertaken to study the effectiveness of antibacterial activity of cement-antibiotic admixtures in vitro and in vivo as well as change of physical properties produced by the incorporation. As conclusions, antibiotic-mixed bone cements have evident effects on growth of inoculated organisms sensitive to added antibiotics whereas cured bone cement itself has been proved not to have any antibacterial activity. The leaching of antibiotics occurs fairly soon, the great majority of the amount within several days. The rest shows slow, delayed leaching over period of three weeks. The weakening of physical properties was not so significant to forbid the application. Resistance to tensile and bending stress was more reduced than that to compression stress. The mixing of two antibiotics(Cephaloridine and Gentamicin powder) together to bone cement revealed double-edged effectiveness to either of gram-positive or negative organisms without any significant illeffects on hardness of cured cement, It is suggested that mixture of two antibiotics to bone cement renders broader blind coverage to unknown causative micro-organisms of postoperative deep infection of total hip replacement arthroplasty.
Anti-Bacterial Agents ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Bone Cements ; Gentamicins ; Hardness ; Hypersensitivity ; In Vitro Techniques ; Methods ; Microbial Viability ; Polymethyl Methacrylate

The giant cell tumor is a primary. neoplasm of bone characterized histollogically by a vascularized network of plumpish or ovoid stromal cells heavily interposed with multinucleated giant cells. The majority of cases occur in patients between 20 and 40 years old and in the long tubular bones, particuarly in proximity to the epiphysis. A rare case of giant cell tumor involving the patella was recently experienced by authors. Case summary with brief review of reference is presented.
Epiphyses ; Giant Cell Tumors ; Giant Cells ; Humans ; Patella ; Stromal Cells

No abstract available.
Hemorrhage*

No abstract available.
Osteogenesis Imperfecta* ; Osteogenesis* ; Osteotomy*

PURPOSE: To evaluate the optimal pulse sequences in the detection of erosions and for the discrimination of theeffusion from pannus. MATERIALS AND METHODS: MR studies were performed in thirteen patients with clinical diagnosis of rheumatoid arthritis. We used a 1.5T MR unit with single or dual 3 inch coil. We compared coronal images at the same location, obtained with pulse sequences of T2, T2 with fat saturation, and postcontrast T1 with fat suppression. Erosions were assessed by comparing the count of the numbers of erosions depending on each imaging method. A four point scoring systems was used for the comparison of conspicuitof lesion. RESULTS: T2WI with fat suppression and postcontreat T1WI with fat suppresison were better than conventional T2WI in the detection of erosions. The pannus had a heterogeneous signal on T2WI, some of which were enhanced after the intravenous injection of MR contrast a gents. CONCLUSION: We suggest that the fat suppression TIWI with enhacnement or the fat suppression T2WI were better than conventional T2WI for detecting both bone erosion and pannus. The postcontrast MR imaging may often be helpul in distinguishing pannus from the effusion.
Arthritis, Rheumatoid* ; Diagnosis ; Discrimination (Psychology) ; Humans ; Injections, Intravenous ; Magnetic Resonance Imaging* ; Wrist*

No abstract available.
Diagnosis* ; Magnetic Resonance Imaging* ; Spondylitis*

Rickets is a syndrome, characterised pathophysiologically by a failure of normal mineralization of bone and epiphyseal cartilage and clinically by skeletal deformity in growing children. The four principal causes of rickets are; vitamin D deficency, renal tubular insufficiency, chronic renal insufficiency, and hypophosphatasia. Of these, vitamin D resistant rickets may result from primary defect in function of the renal tubular reabsorption for phosphorus, later accompsnied with secondary hyperparathyroidism. We experiened a rare case of hypophosphstemic vitamin D resistant rickets accompanied with secondary hyperparathyroidism in adolescence.
Adolescent ; Child ; Congenital Abnormalities ; Familial Hypophosphatemic Rickets ; Growth Plate ; Humans ; Hyperparathyroidism, Secondary ; Hypophosphatasia ; Miners ; Phosphorus ; Renal Insufficiency, Chronic ; Rickets ; Vitamin D ; Vitamins

No abstract available.
Humerus*

Craniometaphyseal Dysplasia is characterized by hyperostosis of craniofacial bones, with compression of cranial nerves at the foramina, and by changes in the metaphyses of long bones. The changes in long bones resemble to some degree those seen in pyle's disease, but have cretain differences and significant cranial abnormalities with which differential diagnosis could be made with certainty. An interesting and unusual patient diagnosed Craniometaphyseal Dysplasia was recently experienced by authors. The case report with brief review of literstures in presented.
Cranial Nerves ; Diagnosis, Differential ; Humans ; Hyperostosis