No abstract available.
Succimer* ; Thymoma*

The previous reports have indicated that both the DMSA scan and the DTPA scan were significantly related with the relative renal function ( RRF) and there was a close relationship between the DMSA scan and the DTPA scan in the evaluation of the RRF We reviewed our experience with 24 cases, in which the DMSA scan and the DTPA scan were performed within 2 weeks from January 1987 to April 1991. The DMSA scan was more reliable than the DTPA scan and the difference of the RRF between right and left side by the DMSA scan was more apparent than that by the DTPA scan. However, in infants, both scans showed the reversed results. Our study suggests that DMSA scan is more reliable than the DTPA scan in the evaluation of the RRF, but both renal scans are inappropriate in infants, especially under the age of 1 months.
Humans ; Hydronephrosis* ; Infant ; Pentetic Acid* ; Succimer*

No abstract available.
Nephritis* ; Positron-Emission Tomography and Computed Tomography* ; Succimer*

PURPOSE: To re-evaluate the morphological and functional recovery of conservative treatment of major renal injuries. MATERIALS AND METHODS: We reviewed 68 patients admitted at our hospital due to major renal injury from Jan. 1991 to Dec. 1996. 33 of the 68 patients(48.5 percent) could be managed conservatively without surgery, All patients underwent follow-up abdominal CT and 12 of the 33 patients underwent DMSA renal scan at more than 3 months after injury. RESULTS: The mean function of the injured kidneys in comparison with contralateral kidney was 88.3 percent in case of normal finding in follow-up abdominal CT scan. CONCLUSIONS: We concluded that DMSA renal scan would be the valuable study for evaluation of the functional recovery of major renal injury.
Follow-Up Studies ; Humans ; Kidney ; Succimer ; Tomography, X-Ray Computed

Ectopic scrotum is extremely rare and refers to the anomalous position of one hemiscrotum along the inguinal canal. Only two cases of ectopic scrotum have been reported in Korea. We experienced a case of unilateral ectopic scrotum with crytorchidism. The penis showed normal in appearence. The ectopic scrotum with cryptorchidism was found on the left inguinal area. And there was left ipsilateral renal agenesis on the ultrasonogram and DMSA renal scanning. We successfully performed scrotoplasty and orchiopexy.
Cryptorchidism* ; Inguinal Canal ; Korea ; Male ; Orchiopexy ; Penis ; Scrotum* ; Succimer ; Ultrasonography

PURPOSE: The aim of this study was to evaluate the clinical usefulness of measurement of beta2 microglobulin (beta2 MG), N-acetyl-beta-D-glucosaminidase (NAG) of spot urine samples as indices of renal tubular damage and microalbumin of spot urine samples as a parameter of glomerular damage in children with vesicoureteral reflux (VUR) or renal defects. METHODS: We studied 91 children with previous UTI. The children were classified as 62 children without VUR and renal defects (group I), 10 children with VUR, without renal defects (group II), and 19 children with VUR and renal defects (group III). Patients having VUR were separated according to the degree of VUR (mild VUR: VUR grade I-III, severe VUR: VUR grade IV-V). Urinary excretion of beta2 microglobulin (beta2 MG), microalbumin, N-acetyl-beta-D-glucosaminidase (NAG), creatinine were measured in samples of morning urine specimens. Children with VUR or renal defects detected by voiding cystourethrography (VCUG) and DMSA renal scan were investigated. RESULTS: Microalbumin/Cr ratio of spot urine was significantly increased in group III compared group I (42.3+/-27.2 mg/gCr vs 25.2+/-10.9 mg/gCr, P<0.05). NAG/Cr ratio of spot urine was significantly increased in group II compared group I (3.70+/-23.4 mg/gCr vs 18.7+/-12.7 mg/gCr, P<0.05). There was no statistically significant difference of beta2 MG/Cr ratio among three groups. CONCLUSION: Urinary microalbumin excretion of morning urine sample may be a simple and reliable clinical indicators for early identification of renal damage in children with VUR and renal defects. Urinary microalbumin excretion may be useful marker to predict the the severity of VUR.
Acetylglucosaminidase ; Child ; Creatinine ; Humans ; Succimer ; Vesico-Ureteral Reflux

PURPOSE: Renal size is an important indicator to determine adequate organ growth in children. The aim of this study was to estimate renal size with Technesium-99m dimercaptosuccinic acid (DMSA) scan and propose a simple formula for predicting renal length in normal Korean children. METHODS: This study included 346 children (148 boys and 198 girls; age range, 1 month to 17 years) in whom renal length was measured using the DMSA scan. Patients with anatomical renal abnormalities or acute pyelonephritis were excluded. Children were divided into two groups: 214 children (61.8%) were less than a year old (group 1) and 132 (38.2%) were > or =1 year (group 2). RESULTS: Renal length was larger on the left side than the right side, and there was no significant gender-related difference in renal length. We propose the following formula for renal length based on the analysis of the 346 children in our study: the formula was as follows: 4.682xage (month)0.137, R2=0.780. In group 1, the formula was renal length (cm)=0.127xage (month)+5.144, R2=0.354, and in group 2, the formula was 0.334xage (year)+6.477, R2=0.829. CONCLUSION: It is difficult to establish simple formulae in infants (R2=0.354). Therefore, further studies including relevant variables are needed for this age group. We proposed formulae to estimate renal length in Korean children over 1 year of age by using the DMSA scan.
Child* ; Female ; Humans ; Infant ; Kidney* ; Pyelonephritis ; Radionuclide Imaging* ; Succimer*

The effects on renal function following percutaneous nephrolithotomy(PNL) were investigated on 37 patients. The overall success rate was 76%. The success rate on renal stone(79% ) was better than on upper ureter stone(67% ). The complication rate was much lower on later cases according to the increasing experiences and improved technique. The renal function was evaluated on 15 cases using DMSA renal scan and separate creatinine clearance rate pre-and post-operatively. Fourteen cases out of fifteen cases showed no significant renal functional change statistically. However, only one case who had massive renal bleeding for eight days postoperatively showed about 18% reduction of renal function and which case was considered due to major renal vascular damage during PCN tract creation. Conclusively, PNL seemed to be safer and has lower morbidity rate than surgical removal of stone if carried out by experienced hands.
Creatinine ; Hand ; Hemorrhage ; Humans ; Nephrostomy, Percutaneous* ; Pregnenolone Carbonitrile ; Succimer ; Ureter

PURPOSE: We investigated whether a renal size discrepancy on a renal sonogram (US) in children with febrile urinary tract infection (UTI) was correlated with the presence of cortical defects on their dimercaptosuccinic acid (DMSA) renal scan. METHODS: We examined 911 children who were admitted consecutively to our hospital with their first episode of febrile UTI from March 2001 to September 2014. All enrolled children underwent a US and DMSA scan during admission. According to the US findings, including the renal size discrepancy, data were compared between children with positive and negative DMSA scan results. A positive DMSA scan result was defined as reduced or absent tracer localization and indistinct margins that did not deform the renal contour. RESULTS: Mean renal lengths of the right and left kidneys were larger in children with positive DMSA scan results than in children with negative DMSA scan results (63.2±11.3 mm vs. 58.4±7.8 mm, P<0.001; 64.9±11.2 mm vs. 59.9±7.9 mm, P<0.001; respectively). A significant difference was observed in both renal lengths between children with positive and negative DMSA scan results (4.6±3.8 mm vs. 3.3±2.6 mm, P<0.001). A multiple logistic regression analysis, revealed that a small kidney, cortical thinning, and a renal length discrepancy on US findings were significant factors for predicting the presence of cortical defects on an acute DMSA scan [P=0.028, 95% confidence interval (CI) 1.054–2.547; P=0.004, 95% CI 1.354–4.810; P<0.001, 95% CI 1.077–1.190, respectively]. CONCLUSION: In conclusion, a renal size discrepancy on US findings in children with their first episode of febrile UTI was a helpful tool for predicting the presence of cortical defects on an acute DMSA scan.
Child ; Humans ; Kidney ; Logistic Models ; Pyelonephritis ; Succimer ; Urinary Tract Infections

BACKGROUND: Humans are exposed to mercury via many different routes and in different forms. Studies concerned with the exposure in the general population were done many times in the past. But, the treatment of mercury exposure and mercury intoxication is limited. Therefore, chelators such as birth anti lewistite, 2,3-dimercaptopropanol (BAL), dimercaptopropane-1-sulphonate (DMPS), and dimercaptosuccinic acid (DMSA) were given to patients with acute symptoms resulting from the central nervous system due to confirmed mercury poisoning. In this paper, we reported the effects of oral Vitamin C on mercury excretion. METHODS: This study has been reviewed in the clinical findings of 213 patients aged 30-80 who visited Kosin University Gospel Hospital during 3 months from March to September 2007. We measured hair mercury levels at the initial visit and at 3-4 months after the oral vitamin C (4 g/day) treatment. RESULTS: The number of patients who had initial hair mercury level over 1.5 ppm were 57 patients among 213 patients, and 41 patients rechecked the hair mercury level. Twenty patients who had hair mercury level over 1.5 ppm were treated with oral vitamin C for 3 months and rechecked the hair mercury level and 21 patients without vitamin C treatment. The vitamin treatment group had a hair mercury level that was three times lower than the non-treated group. CONCLUSION: The vitamin C oral treatment significantly decreased the level of hair mercury.
Aged ; Ascorbic Acid ; Central Nervous System ; Chelating Agents ; Dimercaprol ; Hair ; Humans ; Mercury Poisoning ; Parturition ; Succimer ; Vitamins