Cefepime is a fourth-generation cephalosporin, developed in 1994, and is well known for its adverse effects. In 2002, the Food and Drug Administration adjusted the labeling to account for increased risk of seizures, encephalopathy and myoclonus, especially in the setting of renal impairment. Here we present a case of an 86-year-old female, undergoing Cefepime treatment, with encephalopathy mimicking acute stroke.
Aged, 80 and over ; Brain Diseases ; Female ; Humans ; Myoclonus ; Seizures ; Stroke ; United States Food and Drug Administration

The pathophysiology of reversible cerebral vasoconstriction syndrome (RCVS) is not known but coexisting vascular lesion, such as carotid artery and vertebral artery dissection, has been reported. However, RCVS concurrent with anterior cerebral artery dissection has never been reported. We describe a 28-year old patient presenting with anterior cerebral artery dissection with RCVS associated with coughing. This case could support the causality between RCVS and arterial dissection.
Anterior Cerebral Artery ; Carotid Arteries ; Cough ; Headache Disorders, Primary ; Humans ; Vasoconstriction ; Vertebral Artery Dissection