1.Current Status and Suggested Future Directions of Nutrition Intervention using Healthy School Tuck Shops: the Teenage Perspective
Suhyun OH ; Kirang KIM ; Ji Yun HWANG
Korean Journal of Community Nutrition 2018;23(3):226-233
OBJECTIVES: This study was conducted to investigate the current status and to suggest future directions for health management of teenagers who use healthy school tuck shops to improve teenagers' eating habits while reducing and preventing obesity. METHODS: A total of 29 students (16 middle school students and 13 high school students) took part in the interview for this study, and the interview was conducted for each school's focus group by using qualitative research methodology. RESULTS: The current status of using healthy school tuck shops and suggested future directions were divided into two categories. Personal barriers such as discrepancies between personal perceptions and behaviors and lack of food choice suitable to individual tastes can be solved by rebuilding the operating system to provide intuitive promotion of behavior and customized products through improvements in existing products and new product development. A lack of consistent management from low utilization convenience and difficulty in maintaining a constant purchase price can be handled by establishing a solution to restricted physical access for products, as well as seeking profit by improving distribution costs via continuous cooperation between the school and community. CONCLUSIONS: Continuous funding and a system that reflects the needs and preferences of healthy school tuck shop users should be applied for sustainable operation of healthy school tuck shops to improve teenagers' eating habits.
Adolescent
;
Eating
;
Financial Management
;
Focus Groups
;
Humans
;
Obesity
;
Qualitative Research
2.Current Status and Suggested Future Directions of Nutrition Intervention using Healthy School Tuck Shops: the Teenage Perspective
Suhyun OH ; Kirang KIM ; Ji Yun HWANG
Korean Journal of Community Nutrition 2018;23(3):226-233
OBJECTIVES: This study was conducted to investigate the current status and to suggest future directions for health management of teenagers who use healthy school tuck shops to improve teenagers' eating habits while reducing and preventing obesity. METHODS: A total of 29 students (16 middle school students and 13 high school students) took part in the interview for this study, and the interview was conducted for each school's focus group by using qualitative research methodology. RESULTS: The current status of using healthy school tuck shops and suggested future directions were divided into two categories. Personal barriers such as discrepancies between personal perceptions and behaviors and lack of food choice suitable to individual tastes can be solved by rebuilding the operating system to provide intuitive promotion of behavior and customized products through improvements in existing products and new product development. A lack of consistent management from low utilization convenience and difficulty in maintaining a constant purchase price can be handled by establishing a solution to restricted physical access for products, as well as seeking profit by improving distribution costs via continuous cooperation between the school and community. CONCLUSIONS: Continuous funding and a system that reflects the needs and preferences of healthy school tuck shop users should be applied for sustainable operation of healthy school tuck shops to improve teenagers' eating habits.
Adolescent
;
Eating
;
Financial Management
;
Focus Groups
;
Humans
;
Obesity
;
Qualitative Research
3.Factors Predicting Response to Splenectomy in Patient with Immune Thrombocytopenia Purpura.
Suhyun HWANG ; Yongwon CHOI ; Byounghoon MIN ; Jiwon YANG ; Joonseong PARK
Soonchunhyang Medical Science 2015;21(2):87-90
OBJECTIVE: Splenectomy has been proposed to be the standard therapy for patients with steroid refractory immune thrombocytopenic purpura (ITP). This study aimed to describe valuable factors predicting the effect of splenectomy in patients with ITP. METHODS: A total of 51 adult patients who underwent splenectomy for steroid refractory ITP were evaluated their medical records retrospectively. The response to the treatment was classified on the basis of the platelet count. RESULTS: The responding group included 35 patients (68.8%), the partial-responding group included 4 patients (7.8%), and non-responding group was 12 patients (23.5%). On univariate analysis, the response of splenectomy correlated with only the intravenous immune globulin (IVIG) response (66.7%, P=0.006), but hemolysis, autoantibody, a presence of accessory spleen, the response of steroid were not significantly associated with the effect of splenectomy. On multivariate analysis, the response of IVIG and the amount of platelet transfusion were independent variables of the response of splenectomy. CONCLUSION: Patients with ITP who have good responses to IVIG are likely to have a good or favorable responses to splenectomy.
Adult
;
Hemolysis
;
Humans
;
Immunoglobulins, Intravenous
;
Medical Records
;
Multivariate Analysis
;
Platelet Count
;
Platelet Transfusion
;
Purpura*
;
Purpura, Thrombocytopenic, Idiopathic
;
Retrospective Studies
;
Spleen
;
Splenectomy*
;
Thrombocytopenia*
4.Rupture of a Superior Mesenteric Artery Pseudoaneurysm Presenting with Asymptomatic Anemia.
Joo Sung KIM ; U Ram JIN ; Gil Ho LEE ; SuHyun HWANG ; Yeonkyung LEE ; Kihyun LIM ; Sun Gyo LIM
Korean Journal of Medicine 2015;88(5):560-563
Anemia is a common cause of referrals to gastroenterologists. Only a small number of anemia cases result from vascular abnormalities. Visceral artery aneurysms and pseudoaneurysms are rare forms of vascular disease that have significant potential for rupture, resulting in potentially life-threatening hemorrhaging. We present the case of a 70-year-old female patient with a pseudoaneurysm of the superior mesenteric artery complicated with rupture, who had no abdominal pain and only anemia.
Abdominal Pain
;
Aged
;
Anemia*
;
Aneurysm
;
Aneurysm, False*
;
Arteries
;
Female
;
Humans
;
Mesenteric Artery, Superior*
;
Referral and Consultation
;
Rupture*
;
Vascular Diseases
5.Acute Suppurative Appendicitis Diagnosed by Acute Lower Gastrointestinal Hemorrhage.
Dae ha KIM ; Ju Han LEE ; Dongwoo KIM ; Suhyun HWANG ; Kyuho KANG ; Ja Seol KOO
The Korean Journal of Gastroenterology 2019;73(1):45-49
A 49-year-old man visited the emergency room of Korea University Ansan Hospital with hematochezia starting the day before the visit. Recently, he was on anti-platelet medication due to hypertension. The patient had no definite symptoms other than hematochezia. Digital rectal exam was positive and laboratory tests showed severe anemia. Sigmoidoscopy was initiated and almost no fecal material was observed in the intestinal tract, allowing insertion into the cecum. Active bleeding from the appendiceal opening was noted. On abdominal CT, contrast enhancement was observed at the tip of the appendix. Under suspicion of acute appendicitis, we consulted with a surgeon. The patient underwent appendectomy with partial cecal resection. Pathologic examination revealed a diagnosis of appendix bleeding due to acute suppurative appendicitis. The patient had no further bleeding after surgery and was discharged in a stable state. Careful observation by the endoscopist is necessary for accurate diagnosis of lower gastrointestinal hemorrhage. Appendiceal hemorrhage is very rarely reported, but it has various pathophysiologies. CT scan is useful when appendiceal hemorrhage is confirmed by endoscopic findings. Surgical treatment was needed in almost all cases reported worldwide. If bleeding from the appendix is confirmed, surgical treatment should be considered for both therapeutic and diagnostic purposes.
Anemia
;
Appendectomy
;
Appendicitis*
;
Appendix
;
Cecum
;
Colonoscopy
;
Diagnosis
;
Emergency Service, Hospital
;
Gastrointestinal Hemorrhage*
;
Gyeonggi-do
;
Hemorrhage
;
Humans
;
Hypertension
;
Korea
;
Middle Aged
;
Sigmoidoscopy
;
Tomography, X-Ray Computed
6.Is robot-assisted laparoscopic myomectomy limited in multiple myomas?: a feasibility for ten or more myomas
Hyunkyung KIM ; Suhyun SHIM ; Youngbin HWANG ; Minkyoung KIM ; Hyejin HWANG ; Younjee CHUNG ; Hyun Hee CHO ; Mee Ran KIM
Obstetrics & Gynecology Science 2018;61(1):135-141
OBJECTIVE: To evaluate the feasibility of robot-assisted laparoscopic myomectomy in multiple myomas over 10. METHODS: A retrospective study was conducted for 662 patients who underwent robot-assisted laparoscopic myomectomy and open myomectomy by a single operator in a tertiary university hospital. RESULTS: A total of 30 women underwent removal of 10 or more uterine myomas by robotics and 13 patients were selected for this study. The average number of myomas removed was 13.7 (range 10–20). The maximum diameter of the myomas was 6.8 cm (range 5.0–10.0 cm). The sum of the diameters of each myoma was 34.7 cm (range 20.0–54.5 cm) and the mass of resected myomas for each case was 229.1 g (range 106.8–437.9 g). In no case was the robotic procedure converted into conventional laparoscopy or laparotomy, and all patients recovered without any major complications. In comparison with 13 cases of open myomectomy during the same period, robotic surgery took longer time than open surgery (360.5 vs. 183.8 minutes; P=0.001) but had shorter postoperative hospital days after surgery (mean 2.5 vs. 3.5 days; P=0.003). CONCLUSION: Robot-assisted laparoscopic myomectomy could be an alternative to laparotomic myomectomy for numerous myomas over 10 in number.
Female
;
Humans
;
Laparoscopy
;
Laparotomy
;
Leiomyoma
;
Minimally Invasive Surgical Procedures
;
Myoma
;
Retrospective Studies
;
Robotic Surgical Procedures
;
Robotics
;
Uterine Myomectomy
7.Abnormal Development of Neural Stem Cell Niche in the Dentate Gyrus of Menkes Disease
Sung-kuk CHO ; Suhyun GWON ; Hyun Ah KIM ; Jiwon KIM ; Sung Yoo CHO ; Dong-Eog KIM ; Jong-Hee CHAE ; Dae Hwi PARK ; Yu Kyeong HWANG
International Journal of Stem Cells 2022;15(3):270-282
Background and Objectives:
Menkes disease (MNK) is a rare X-linked recessive disease, caused by mutations in the copper transporting ATP7A gene that is required for copper homeostasis. MNK patients experience various clinical symptoms including neurological defects that are closely related to the prognosis of MNK patients. Neural stem cells (NSCs) in the hippocampal dentate gyrus (DG) produce new neurons throughout life, and defects in DG neurogenesis are often correlated with cognitive and behavioral problems. However, neurodevelopmental defects in the DG during postnatal period in MNK have not been understood yet.
Methods:
and Results: Mottled-brindled (Mo Br/y ) mice (MNK mice) and littermate controls were used in this study. In vivo microCT imaging and immunohistochemistry results demonstrate that blood vasculatures in hippocampus are abnormally decreased in MNK mice. Furthermore, postnatal establishment of NSC population and their neurogenesis are severely compromised in the DG of MNK mice. In addition, in vitro analyses using hippocampal neurosphere culture followed by immunocytochemistry and immunoblotting suggest that neurogenesis from MNK NSCs is also significantly compromised, corresponding to defective neurogenic gene expression in MNK derived neurons.
Conclusions
Our study is the first reports demonstrating that improper expansion of the postnatal NSC population followed by significant reduction of neurogenesis may contribute to neurodevelopmental symptoms in MNK. In conclusion, our results provide new insight into early neurodevelopmental defects in MNK and emphasize the needs for early diagnosis and new therapeutic strategies in the postnatal central nerve system damage of MNK patients.